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Gut flora probiotic
1.
2. Gut Flora & Probiotic 11
Saira Salmon DipNN, MFNTP
3. Your gut….
• Is teeming with microbes – up to 70% of the
body’s total number
• It is an extremely complex ecosystem
harbouring more than 100
trillion micro-organisms
• There are thought to be
around 30 – 40 different
species of bacteria.
4. Many of these have a symbiotic relationship with us –
and help to keep less beneficial strains at bay.
A healthy gut in an adult human has somewhere in the
region of 2 kg of these bacteria in the gut.
5. They play a vital role in the body – without them
we would not survive.
Sterilise your gut and you die, have good levels
of probiotic bacteria and you thrive!
7. What Role Do They Play?
Beneficial bacteria take part in our digestion and
absorption of food
They produce a number of enzymes to break down
proteins, carbohydrates, fibre and fats
They produce various substances to transport
vitamins, minerals and other nutrients through the
gut wall
8. What Role Do They Play?
They can actively synthesize nutrients such as
K2, many of the B vitamins and some amino
acids
They help chelate heavy metals from our
system.
Help control parasites
9. What Role Do They Play
They play a crucial role in our immune
system, keeping the body’s immunity active.
Around 83% of our immunity is located in the
gut wall.
Beneficial flora imbalance will have an
immediate impact on immune system.
10. How it Starts
We inherit our gut flora from our mother at birth.
As the baby comes through the birth canal it
swallows its first mouthfuls of bacteria, which begin
to inhabit baby’s sterile gut.
Breast feeding continues the process.
It takes about 2 years for a baby’s immune system
to fully develop
11. Dysbiosis
When gut flora is damaged or in imbalance it is
called dysbiosis.
Opportunistic gut microbes including yeast, harmful
bacteria, viruses and parasites
start to take hold.
They can be very difficult to
eradicate once they have moved
in.
13. What Can Damage Gut Flora
Antibiotics Steroids, The Pill
Other drugs Stress
Poor diet Infections
Bottle feeding Old Age
Pollution Radiation
Alcohol Toxic chemicals
Dental work
14. When gut flora is damaged…
• Microbes ie. ‘bad’ bacteria, multiply.
• They can perforate and damage the thin layer
of epithelial cells lining the gut, which then
allows unwanted microbes and toxins to inter
into our bloodstream.
• This is termed ‘leaky gut’ syndrome.
15. Leaky gut
• Causes include:
– poorly digested foods alcohol
– antibiotics or infection painkillers
– heavy metal toxicity smoking
– birth control pills antacids
– chlorinated water food additives
– high homocysteine levels parasites, yeasts food
allergies
• Underactive & constipated bowel will also cause
problems
16. Leaky gut
Consequences
Body has to use whatever routes it can to eliminate toxins.
They initially get taken to liver.
The increased flow leads to blocked detox pathways
All liver functions suffer
Toxins bypass the filtering and go into blood stream.
Get taken:
To lungs -asthma, and other chronic lung conditions
To skin – eczema, rashes and other skin problems
Urine – cystitis, thrush, bedwetting
Through mucous membranes – sinusitis, post nasal
drip, rhinitis, gingivitis, vaginitis, diarrhea/constipation
17. all this – and more – from damaged gut flora
These guys are important!
18. Bowel Bacteria & Health
IBS
A variety of studies have found evidence
of the benefit of using probiotics in the
management of irritable bowel syndrome.
19. Bowel Bacteria & Health
Cholesterol
Some strains of bowel bacteria, including
L. Acidophilus and Bifidobacteria seem to have a
direct action on lowering cholesterol levels.
20. Bowel Bacteria & Health
Colon Cancer
Bowel bacteria have also been linked to
colon cancer.
Many enzyme pathways are influenced eg.
Bifido longum inhibits B-glucuronidase, elevated
levels of which are associated with increased
colon cancer
21. Bowel Bacteria & Health
Autism
People with autistic spectrum disorders
have been shown to have imbalances in gut
bacteria. Research in this field suggests
improving bowel flora levels is an important part
of managing this disorder.
22. Bowel Bacteria & Health
Autism
People with autistic spectrum disorders
have been shown to have imbalances in gut
bacteria. Research in this field suggests
improving bowel flora levels is an important part
of managing this disorder.
23. Bowel Bacteria & Health
Therapeutically
A probiotic is used within a wide range of
therapeutic regimes by practitioners
24. How to Maintain Probiotic Health
Avoid things which damage gut flora
Eat prebiotic foods
Raw chicory root, Jerusalem artichoke, garlic and
leek, asparagus, banana, raw and cooked onion.
25. How to Maintain Probiotic Health
Eat probiotic (fermented) foods
Live yoghurt, Miso, tempeh, sauerkraut, natto
Supplement with a good probiotic
26. Introducing Probiotic 11!
A high potency, broad spectrum probiotic.
11 different strains of friendly bacteria.
Contains almost 12 billion bacteria per serving.
Enteric coated to disperse in the intestines.
In a prebiotic blend to spread and nourish.
27. The Bacteria in Probiotic 11
7 strains of Lactobacillus:
• Lactobacillus acidophilus (acid loving milk
bacteria).
Grown on milk but doesn’t contain it, and helps
break down lactose.
Supports immune system by stimulating production
of regulation T cells
Inhibits patogenic growth in urinary tract
infections by adhering to uro-epithelial cells
28. The Bacteria in Probiotic 11
• L rhamnosus
- may help reduce the incidence of developing
childhood allergies and tooth decay in children
- Increases cell mediated immunity in Chron’s
disease
• L brevis
• L bulgaricus
• L plantarum
• L casei
• L salvarius
29. The Bacteria in Probiotic 11
3 strains of Bifidobacterium:
• Bifidobacterium longum
– creates B vitamins.
• B.bifidum
– significantly improves pain and bowel habits in irritable bowel
syndrome
– Prevents diarrhea that occurs with post-antibiotic overgrowths of C
difficile and Candida albicans
• B.infantis
– Helped improve abdominal pain and discomfort in IBS
– see table on Wikipedia for more information.
30. The Bacteria in Probiotic 11
Streptococcus thermophilus
Used to start fermentation process of
making yoghurt.
Also some interesting research conducted on this – see
Wikipedia for more info.
31. The Bacteria in Probiotic 11
FOS (Fructo Oligo Saccharides )
Prebiotic - food for healthy bacteria
Help to nourish and spread the bacteria
throughout the gut.
32. When to Use Probiotic 11
• Following a course of antibiotics, or a cleanse.
• Before and after hospital treatment
• During preconception & pregnancy
• With confirmed dairy intolerance
• During treatment for candidiasis
33. When to Use Probiotic 11
• During and after a stomach upset
• With those prone to low mood / behavioural
disturbance
• With someone who has regular
colonic irrigation
• Combined with Caprylic Acid for a
week before going on holiday, until
returning home.
34. How to Use Probiotic 11
Take 1-2 capsules daily
with a meal
Each pot last 6 weeks
- 2 months.
35. What Makes Probiotic 11 Special?
One of the most potent probiotics available on
the market
Also unusual to get so many strains in
one supplement – would appeal to
many clinical therapists.
Built in prebiotic
Enteric coated
36. You can buy this product directly from the
company at a wholesale price.
Buy products and become a distributor of NSP
http://www.naturessunshine.com/
• Sponsor's Country: BELARUS
• Sponsor's Account Number (ID): 1007815
Main source of K2 and many B vitamins. Why? These are water soluble and will not stay in body long so will be periods in day when we are deficient. Gut flora provides our own factory of these to release these into our bloodstream all the time.
Naturopaths believe that nearly all disease can be traced back to damaged or abnormal gut flora.
Caesarean births, lack of breast feeding etc all impact on gut flora and immune system. Bottle fed babies acquire a completely different balance of gut flora to those breast fed. Medication, antibiotics etc all affect this as well.
V vulnerable to antibiotics – die first and take weeks to recover giving time for less vulnerable microbes like candida and clostridia to take over. Other drugs – all prescription medications taken on a repeat basis will change the makeup of the gut floraBottle feeding – much higher chance of allergies, eczema, asthma, glue ear etcDental work – most of what he puts into your mouth is toxic to gut flora and will be for weeks afterwards
Behavioural changes in children, failure to thrive
Botschinsky B et al (2011) A review of the evidence available for the use and effectiveness of probiotic drinks and supplements for the treatment of IBS> Int J Probitoics Prebitoics 6:21-33, 2011Moayyedi P et al (2008) The efficacy of probitoics in the therapy of irritable bowel syndrome: a systematic review. E Gut 17Wu (2010) Complementary and Alternataive Medicine Modalities for the Treatment of IBS: Fact or Myths? Gastr Hep 6: 705-711
Grill, J.P. et al (1995) Purification and characterisation of conjugated bile salt hydrolase from Bifidobacterium longum BB536. Appl Environ Microbiol 61:2577–2582Lye, H. et al (2009) The improvement of hypertension by probiotics: Effects on cholesterol, diabetes, rennin and phytoestrogens. Int J Mol Sci 10:3755-3775Oh, C.Y., Lee, W.K. (2000) Cholesterol lowering effect of lactic acid bacteria isolated from the human intestine. Korean J Vet Public Health 24:181-188Ooi, L-G., Liong, M-T. (2010) Cholesterol lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings. Int J Mol Sci 11:2499-2522
Iannitti, T., Palmeieri, B., (2010) Therapeutical use of probiotic formulations in clinical practice. Clin Nutr 1-25Kulkarni, N., Reddy, B.S. (1994) Inhibitory effect of Bifidobacterium longum cultures on the azoxymethane induced aberrant crypt foci formation and faecal bacterial ß-glucuronidase. Proc Soc Expt Biol Med 207: 278-283Rowland, I. (2008) Probiotics and cancer – from in vitro to human studies. Int J Probiotics Prebiotics 3:165-168Tang, Y. et al (2011) The role of short-chain fatty acids in orchestrating two types of programmed cell death in colon cancer. Autophagy 7:235-7
Adams, J. et al (2011) Gastrointestinal flora and gastrointestinal status in children with autism–comparisons to typical children and correlation with autism severity Gastroenterology 11:22Finegold, et al (2010) Pyrosequencing study of fecal microflora of autistic and control children. Anaerobe 16:444-53Garvey, J. (2002) Diet in autism and associated disorders. J Fam Health Care 12:34-38Melmed, R. et al (2000) Metabolic markers and GI symptoms in children with autism and related disorders. J Pediatr Gasteroenterol Nutr 31:31-32
Adams, J. et al (2011) Gastrointestinal flora and gastrointestinal status in children with autism–comparisons to typical children and correlation with autism severity Gastroenterology 11:22Finegold, et al (2010) Pyrosequencing study of fecal microflora of autistic and control children. Anaerobe 16:444-53Garvey, J. (2002) Diet in autism and associated disorders. J Fam Health Care 12:34-38Melmed, R. et al (2000) Metabolic markers and GI symptoms in children with autism and related disorders. J Pediatr Gasteroenterol Nutr 31:31-32
Adams, J. et al (2011) Gastrointestinal flora and gastrointestinal status in children with autism–comparisons to typical children and correlation with autism severity Gastroenterology 11:22Finegold, et al (2010) Pyrosequencing study of fecal microflora of autistic and control children. Anaerobe 16:444-53Garvey, J. (2002) Diet in autism and associated disorders. J Fam Health Care 12:34-38Melmed, R. et al (2000) Metabolic markers and GI symptoms in children with autism and related disorders. J Pediatr Gasteroenterol Nutr 31:31-32
IBS – William 2008Diarrhea – Plummer 2004Whorwell PJ, Altringer L, Morel J et al (July 2006). "Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome". Am. J. Gastroenterol.101 (7): 1581–90. doi:10.1111/j.1572-0241.2006.00734.x. PMID 16863564.
IBS – William 2008Diarrhea – Plummer 2004Whorwell PJ, Altringer L, Morel J et al (July 2006). "Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome". Am. J. Gastroenterol.101 (7): 1581–90. doi:10.1111/j.1572-0241.2006.00734.x. PMID 16863564.