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General Principles of Skin Graft and
Flaps
Presenter;Dr Dagmawi.Geremew,SR2
Moderator;DrYigeremu Kebede(Consultant
General Surgeon,Plastic & Reconstructive Surgeon)
Nov10,2021
Outlines
Anatomic Review
Principles of Skin Grafting
 Introduction
 Classifications & Types
 Indications and Contraindications
 Operative Techniques
 Complications
Prnciples of Flap Surgery
 Introduction
 Applications
 Classification
 Principles
 Complications
Summary
Skin Anatomy
• The largest organ in the human body
• It serves Many functions
Three properties essential for
understanding reconstruction :
• Elasticity
• Extensibility
• Resilience
• Two layers
Blood Supply
“Plastic surgery is a constant battle between
blood supply and beauty.”
Sir Harold Delf Gillies
Angiosome
Principles of Skin Grafting
Introduction
• Graft is something that is removed from the
body, is completely devascularized, and
replaced in another location.
• originated among the Tilemaker caste in India
approximately 3000 years ago.
• a standard option for closing defects that
cannot be closed primarily
Classfication
Autografts
Isograft / Syn graft
Allograft
Xenografts
Composite Grafts
Indications
• Coverage of a skin defect due to many causes
• To cover chronic wounds
• As an adjunct to tissue flap reconstructive techniques.
Contraindications
• Wounds with avascular bed, Infection
• Wounds with deep spaces and exposed structures
Types
Characterstics
Comparison
Graft Take
Phase 1 -Plasmatic / serum imbibition
• Lasts for 24 to 48 hours
• Immediate post graft survival
• A fibrin layer forms
• Diffusion is the route
• Edematous and in anaerobic metabolism
• Adding to pre-graft weight
Phase 2 –Revascularization
• Lasts 2-7days
1Theory of inosculation
2Theory of vascular ingrowth from recipient bed
3Theory of formation of acellular vascular channels
• Signs of perfusion
• Risky period affected by Factors
• The dressing is critical
Phase 3;Maturation
• graft and surrounding tissues remodel and
contract
• 1 year to complete maturation
• Disappearance of immature vessels
Graft contracture
Primary contraction
Secondary contraction
Choice of Selection
The size of the defect to cover,
The anatomic area to reconstruct,
The availability of donor sites and
The anticipated wound contraction
The Degree of Take
Colour Match
Texture
Operative Techniques
• Pre-operative preparation
• Patient optimization
• Treatement of any systemic infection, anemia
and nutritional support
• Treatement of co morbid medical illnesses if
any
Donor site selection
Recipient site preparation
Well vascularized
Free of all necrotic / ischemic tissue,
cellulitis, purulent drainage and
significant edema.
Hemostasis
Low bacterial count
Trimming
Irrigation
Procedure ; Graft harvesting – STSG
Graft harvesting – FTSG
• Scalpel
• marking.
• tumescent technique
• Incision & elevation
• Defatting
• Close donor site
Meshing skin graft
• Expansion
• Prevention
 Graft mesher
 Pie crusting
Graft inset
-STSG
• transferred dermis side down
• Then long bolster sutures are tied
FTSG -Fit
• Immobility
Post – operative Recipient site care
Immobilization
Why
Prevent shearing of the graft
Prevent accumulation of fluid
 Facilitates take phases
How
Compression
Splints or casts
A bolster dressing
Sealants
When First dressing change?
Post – operative Donor site care
more painful
Infection Monitoring
Average 7-10 days to heal
• Wet phase
• Dry phase
• Primary dressings should remain
Functional Recovery
• STSGs remain without glandular function or
hair growth
• hair regrowth 2–3 months after FTSG
• sensitivity of the grafted area after 1 year
• Sensory complaints
• sweat glands reactivate up to 3 months
;Moisturizers
Graft failure
Causes
• Collection
• Instability
• Infection
• Nontake
• Minimized by careful
preparation and early
inspection
Signs
• Persistently white
graft
• Dry black graft
• Mobile
• Loss;partial vs
complete
The Reconstructive Ladder
• A systematic approach
that facilitates decision
making when
reconstructing a defect.
• Progresses from simple
to complex choices
• Reconstructive
“elevator”
• The best solution to a
reconstructive dilemma
Principles of Flap surgery
Introduction
• A unit of tissue transferred from a donor to a
recipient site while maintaining its blood
supply independent of the injured area
• The term flap originated from the Dutch word
“flappe”
• Sushruta Samita, 600 BC
• Vary greatly in complexity
Applications
● When Grafting not amenable
● Replace tissue loss
● restore form and function
● Provide skin coverage through which surgery can be
carried on latter
● Provide padding over bony prominences
● Bring in better blood supply to poorly vascularized bed
● Improve sensation to an area
● Bring in specialized tissue for reconstruction such as
bone or functioning muscle
Classification
complete classification of flaps
■ Circulation: medial
circumflex femoral artery
■ Constituents: gracilis
muscle
■ Contiguity: free flap
■ Construction: antegrade
flow
■ Conditioning: none
■ Conformation: muscle
only
1,Circulation
• Random cutaneous flaps
• Are based on random, nondominant contributions from the
dermal and subdermal plexus.
• L:W ratio of flap is critical for flap survival, & limits their
ability to reliably cover large defects.
• The ratio had to be 1:1, maximum of 1:1.5 for the flap to
survive.
• Even though the source artery is not known, if the ratio is
1:1 the flap survives.
• Reliable first choices for coverage of smaller defects
throughout the body
Axial flaps
• Based on a reliable and anatomically defined vascular
territory,
• Longitudinally oriented within the flap that extends
beyond the base of the flap.
• Preferred for coverage of moderate to large defects.
• Delay procedures are often unnecessary - Axially oriented
circulation
• limitation - limited topographic arc of rotation when
pedicled
• Overcome by microvascular free tissue transfer
2,Composition
 Perforator flap
 Fasciocutaneous flap
 Musculocutaneous flap
 Osseous flap
 Osteomyocutaneous flap
perforator flap
• isolated perforator(s).
• A muscle perforator.
• A septal perforator.
• muscle perforator flap.
DIEP
• septal perforator flap.
RAP
Myocutaneous Flaps
Uses
Functional muscle flap
Sensate Myocutaneous flap
Coverage of complex wounds
Chronic vascular insufficiency
Chronic radiation wounds
Exposed or infected
prosthesis
The disadvantages
39
Arc of Roatation
may prevent successful
flap transposition
Depends on
•The No of Pedicles
•location of the
dominant vascular
pedicle
Safe standard arc of
rotation
Reverse arc of rotation
Fasciocutaneous Flaps
3,Contiguity
• Proximity to the defect
Local Flaps
Regional flaps
Distant flaps
Local Flaps
classified by their mov’t to resurface the defect
Advancement Flaps
● Moved primarily in a straight line from the
donor site to the recipient site.
● No rotational or lateral movement is applied.
● Can be:
○ Single pedicle
○ Bipedicle
○ V-Y/Y-V advancement
Rotational flap
● Semi-circular flap that rotate around a fixed pivot point
● The donor site is closed by sutures or with a skin graft.
● Rotation is facilitated by:
○ back-cutting or
○ excising a Burow’s triangle
Transposition flaps
● square or rectangular flaps which rotated about a pivot
point into an immediately adjacent defect.
● The more the flap is rotated, the shorter the it
becomes.
● Most commonly used in head and neck
● Variations:
○ Rhomboid
○ Z- plasty
Interpolation Flap
● Similar to transposition flap except the
pedicle pass over or under the intervening
tissue
● Pedicle will be divided after revascularization
● Used for large or deep defect where adjacent
local tissue are insufficient
Regional Flaps
Utilized to cover large
defects which require
bulk
1. PMMF 2. DPF
47
Distant Flaps
● Outside the anatomic
region of the defect
● Two types:
○ Direct
○ Free flaps
48
4,Construction (flow)
• Unipedicle
• Bipedicle
• Antegrade
• Retrograde
• Turbocharged
• Supercharged
• Arterialized venous
5,Conditioning
Delayed Flap
Prelaminated Flap
Prefabricated Flap
Sensory Flap
Functional Flap
Tissue Expansion
The Delay phenomenon
A Two Staged procedure to increase survival &
Territory
Important for selected flaps
Standard Delay vs Strategic Delay
Stage 1;Incision or Ligation
Stage 2;Transfer
Mechanism
• Metabolic Changes,Acclimatization
• Depletetion ofvasoconstriction and
prothrombotic substances in the skin flap
• vascular territory expansion by opening
existing choke arteries
• Induction of angiogenesis
• sympatholytic state
6,Conformation
Post operative care
• Pivotal
• Analgesics,Antibiotics,Anticoagulation
• Avoid Pressure,Elevation
• Avoid Motion,Splints but not Circuar Casts
• Avoid weight bearing
• Drains
• Multi disceplinary
Post operative Flap Monitoring
• Mandatory.
• clinical observation.
• Tissue color, warmth & turgor, capillary refill
time
• Doppler ultrasound and tissue oximetry
should also be used when available
56
Principles of Flap
Surgery
Flap Selection
● Discussion
● Step-wise approach
● Size and location of flap
● Accurate Evaluation of the defect
● Angiosome Adherence
● Location
● Evaluation of surrounding defect
● Size of defect
● Functional and aesthetic consideration
57
Flap complicationS
Flap necrosis;Total vs partial
Intrinsic and Extrinsic Cause,Patient factors
Vascular compromise
Complications specific to the donor site
Hematoma,Seroma,SSI
Prevention
1,Judgment
Inadequate
preparation
Inadequate flap
design
Inadequate
knowledge of
anatomy.
2,Technique, and
3,patient management
60
Skin Grafts Vs Flaps
Summary
• Vascular Anatomy is the core Prerequiste for
Reconstruction
• Skin Graft is the Simplest tool
• Flap Is Vascularized Unlike Graft
• Post operative care of Reconstruction sites is
of equivalence with the initial Reconstructive
Process
• Prevention is the best tool to avoid Failure
References
1. Neligan Plastic Surgery 4th Edition Volume 1
2. Grabb and Smith’s Plastic Surgery Eighth Edition
3. Selected Reading In Plastic and Reconstructive
Surgery
4. Handbook Of Plastic Surgery 3rd Edition
5. Arterial Anatomy Of Skin Flaps by George C. Cormack
and B . George H. Lamberty 2nd edition
6. Schwartz’s Principles of Surgery 11th Edition
7. Uptodate 2021 62
Thank You!

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By Dr Dagmawi GeremewGeneral Principles of Skin Graft and Flaps

  • 1. General Principles of Skin Graft and Flaps Presenter;Dr Dagmawi.Geremew,SR2 Moderator;DrYigeremu Kebede(Consultant General Surgeon,Plastic & Reconstructive Surgeon) Nov10,2021
  • 2. Outlines Anatomic Review Principles of Skin Grafting  Introduction  Classifications & Types  Indications and Contraindications  Operative Techniques  Complications Prnciples of Flap Surgery  Introduction  Applications  Classification  Principles  Complications Summary
  • 3. Skin Anatomy • The largest organ in the human body • It serves Many functions Three properties essential for understanding reconstruction : • Elasticity • Extensibility • Resilience • Two layers
  • 4. Blood Supply “Plastic surgery is a constant battle between blood supply and beauty.” Sir Harold Delf Gillies
  • 7. Introduction • Graft is something that is removed from the body, is completely devascularized, and replaced in another location. • originated among the Tilemaker caste in India approximately 3000 years ago. • a standard option for closing defects that cannot be closed primarily
  • 8. Classfication Autografts Isograft / Syn graft Allograft Xenografts Composite Grafts
  • 9. Indications • Coverage of a skin defect due to many causes • To cover chronic wounds • As an adjunct to tissue flap reconstructive techniques. Contraindications • Wounds with avascular bed, Infection • Wounds with deep spaces and exposed structures
  • 10. Types
  • 13. Graft Take Phase 1 -Plasmatic / serum imbibition • Lasts for 24 to 48 hours • Immediate post graft survival • A fibrin layer forms • Diffusion is the route • Edematous and in anaerobic metabolism • Adding to pre-graft weight
  • 14. Phase 2 –Revascularization • Lasts 2-7days 1Theory of inosculation 2Theory of vascular ingrowth from recipient bed 3Theory of formation of acellular vascular channels • Signs of perfusion • Risky period affected by Factors • The dressing is critical
  • 15. Phase 3;Maturation • graft and surrounding tissues remodel and contract • 1 year to complete maturation • Disappearance of immature vessels
  • 17. Choice of Selection The size of the defect to cover, The anatomic area to reconstruct, The availability of donor sites and The anticipated wound contraction The Degree of Take Colour Match Texture
  • 18. Operative Techniques • Pre-operative preparation • Patient optimization • Treatement of any systemic infection, anemia and nutritional support • Treatement of co morbid medical illnesses if any
  • 20. Recipient site preparation Well vascularized Free of all necrotic / ischemic tissue, cellulitis, purulent drainage and significant edema. Hemostasis Low bacterial count Trimming Irrigation
  • 21. Procedure ; Graft harvesting – STSG
  • 22. Graft harvesting – FTSG • Scalpel • marking. • tumescent technique • Incision & elevation • Defatting • Close donor site
  • 23. Meshing skin graft • Expansion • Prevention  Graft mesher  Pie crusting
  • 24. Graft inset -STSG • transferred dermis side down • Then long bolster sutures are tied FTSG -Fit • Immobility
  • 25. Post – operative Recipient site care Immobilization Why Prevent shearing of the graft Prevent accumulation of fluid  Facilitates take phases How Compression Splints or casts A bolster dressing Sealants When First dressing change?
  • 26. Post – operative Donor site care more painful Infection Monitoring Average 7-10 days to heal • Wet phase • Dry phase • Primary dressings should remain
  • 27. Functional Recovery • STSGs remain without glandular function or hair growth • hair regrowth 2–3 months after FTSG • sensitivity of the grafted area after 1 year • Sensory complaints • sweat glands reactivate up to 3 months ;Moisturizers
  • 28. Graft failure Causes • Collection • Instability • Infection • Nontake • Minimized by careful preparation and early inspection Signs • Persistently white graft • Dry black graft • Mobile • Loss;partial vs complete
  • 29. The Reconstructive Ladder • A systematic approach that facilitates decision making when reconstructing a defect. • Progresses from simple to complex choices • Reconstructive “elevator” • The best solution to a reconstructive dilemma
  • 31. Introduction • A unit of tissue transferred from a donor to a recipient site while maintaining its blood supply independent of the injured area • The term flap originated from the Dutch word “flappe” • Sushruta Samita, 600 BC • Vary greatly in complexity
  • 32. Applications ● When Grafting not amenable ● Replace tissue loss ● restore form and function ● Provide skin coverage through which surgery can be carried on latter ● Provide padding over bony prominences ● Bring in better blood supply to poorly vascularized bed ● Improve sensation to an area ● Bring in specialized tissue for reconstruction such as bone or functioning muscle
  • 34. complete classification of flaps ■ Circulation: medial circumflex femoral artery ■ Constituents: gracilis muscle ■ Contiguity: free flap ■ Construction: antegrade flow ■ Conditioning: none ■ Conformation: muscle only
  • 35. 1,Circulation • Random cutaneous flaps • Are based on random, nondominant contributions from the dermal and subdermal plexus. • L:W ratio of flap is critical for flap survival, & limits their ability to reliably cover large defects. • The ratio had to be 1:1, maximum of 1:1.5 for the flap to survive. • Even though the source artery is not known, if the ratio is 1:1 the flap survives. • Reliable first choices for coverage of smaller defects throughout the body
  • 36. Axial flaps • Based on a reliable and anatomically defined vascular territory, • Longitudinally oriented within the flap that extends beyond the base of the flap. • Preferred for coverage of moderate to large defects. • Delay procedures are often unnecessary - Axially oriented circulation • limitation - limited topographic arc of rotation when pedicled • Overcome by microvascular free tissue transfer
  • 37. 2,Composition  Perforator flap  Fasciocutaneous flap  Musculocutaneous flap  Osseous flap  Osteomyocutaneous flap
  • 38. perforator flap • isolated perforator(s). • A muscle perforator. • A septal perforator. • muscle perforator flap. DIEP • septal perforator flap. RAP
  • 39. Myocutaneous Flaps Uses Functional muscle flap Sensate Myocutaneous flap Coverage of complex wounds Chronic vascular insufficiency Chronic radiation wounds Exposed or infected prosthesis The disadvantages 39
  • 40. Arc of Roatation may prevent successful flap transposition Depends on •The No of Pedicles •location of the dominant vascular pedicle Safe standard arc of rotation Reverse arc of rotation
  • 42. 3,Contiguity • Proximity to the defect Local Flaps Regional flaps Distant flaps
  • 43. Local Flaps classified by their mov’t to resurface the defect Advancement Flaps ● Moved primarily in a straight line from the donor site to the recipient site. ● No rotational or lateral movement is applied. ● Can be: ○ Single pedicle ○ Bipedicle ○ V-Y/Y-V advancement
  • 44. Rotational flap ● Semi-circular flap that rotate around a fixed pivot point ● The donor site is closed by sutures or with a skin graft. ● Rotation is facilitated by: ○ back-cutting or ○ excising a Burow’s triangle
  • 45. Transposition flaps ● square or rectangular flaps which rotated about a pivot point into an immediately adjacent defect. ● The more the flap is rotated, the shorter the it becomes. ● Most commonly used in head and neck ● Variations: ○ Rhomboid ○ Z- plasty
  • 46. Interpolation Flap ● Similar to transposition flap except the pedicle pass over or under the intervening tissue ● Pedicle will be divided after revascularization ● Used for large or deep defect where adjacent local tissue are insufficient
  • 47. Regional Flaps Utilized to cover large defects which require bulk 1. PMMF 2. DPF 47
  • 48. Distant Flaps ● Outside the anatomic region of the defect ● Two types: ○ Direct ○ Free flaps 48
  • 49. 4,Construction (flow) • Unipedicle • Bipedicle • Antegrade • Retrograde • Turbocharged • Supercharged • Arterialized venous
  • 50. 5,Conditioning Delayed Flap Prelaminated Flap Prefabricated Flap Sensory Flap Functional Flap Tissue Expansion
  • 51. The Delay phenomenon A Two Staged procedure to increase survival & Territory Important for selected flaps Standard Delay vs Strategic Delay Stage 1;Incision or Ligation Stage 2;Transfer
  • 52. Mechanism • Metabolic Changes,Acclimatization • Depletetion ofvasoconstriction and prothrombotic substances in the skin flap • vascular territory expansion by opening existing choke arteries • Induction of angiogenesis • sympatholytic state
  • 54. Post operative care • Pivotal • Analgesics,Antibiotics,Anticoagulation • Avoid Pressure,Elevation • Avoid Motion,Splints but not Circuar Casts • Avoid weight bearing • Drains • Multi disceplinary
  • 55. Post operative Flap Monitoring • Mandatory. • clinical observation. • Tissue color, warmth & turgor, capillary refill time • Doppler ultrasound and tissue oximetry should also be used when available
  • 57. Flap Selection ● Discussion ● Step-wise approach ● Size and location of flap ● Accurate Evaluation of the defect ● Angiosome Adherence ● Location ● Evaluation of surrounding defect ● Size of defect ● Functional and aesthetic consideration 57
  • 58. Flap complicationS Flap necrosis;Total vs partial Intrinsic and Extrinsic Cause,Patient factors Vascular compromise Complications specific to the donor site Hematoma,Seroma,SSI
  • 61. Summary • Vascular Anatomy is the core Prerequiste for Reconstruction • Skin Graft is the Simplest tool • Flap Is Vascularized Unlike Graft • Post operative care of Reconstruction sites is of equivalence with the initial Reconstructive Process • Prevention is the best tool to avoid Failure
  • 62. References 1. Neligan Plastic Surgery 4th Edition Volume 1 2. Grabb and Smith’s Plastic Surgery Eighth Edition 3. Selected Reading In Plastic and Reconstructive Surgery 4. Handbook Of Plastic Surgery 3rd Edition 5. Arterial Anatomy Of Skin Flaps by George C. Cormack and B . George H. Lamberty 2nd edition 6. Schwartz’s Principles of Surgery 11th Edition 7. Uptodate 2021 62