43 renal pathology
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The document discusses different types of tubulointerstitial diseases including terminology, causes, pathogenesis, and pathology. It describes tubulointerstitial nephritis as inflammation limited to the tubules and interstitium. Causes include infections, drugs, obstruction, immune mechanisms, and idiopathic cases. Acute tubular necrosis is the most common cause of acute kidney injury and results from ischemia or nephrotoxic insults. Chronic kidney disease occurs when glomerular filtration rate falls below 20% and is characterized by prolonged uremic symptoms.
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