1. Università degli Studi di Napoli Facoltà di Medicina e Chirurgia Corso di Laurea per Tecnico della Prevenzione nell’Ambiente e nei Luoghi di Lavoro Corso di Medicina del Lavoro 4 Tossicologia Ambientale ed Occupazionale Docente: Prof. Maurizio Manno

3. A double case of acute chemical poisoning Two workers were found dead in a well where they were burying barrels containing solvents and solid chemical waste from a nearby chemical plant.

4. brain

5. lung

6. lung

13. An unusual winter epidemics: the shoemakers’ polyneuropathy

26. Two interesting cases of selective acute hepato-nephrotoxicity

62. CONCLUSIONS 1. Understanding mechanisms of toxicity may help to clarify the causes and the clinical features of human poisoning. 2. Cases of human poisoning may help to validate mechanistic hypotheses developed in animal models.