Liver cirrhosis is a chronic, progressive disease characterized by diffuse damage to liver cells and the formation of scar tissue. As healthy liver tissue is replaced by scar tissue, the liver loses its normal structure and function. Common causes include chronic hepatitis from alcohol, viruses, and other toxins. Late stage cirrhosis results in liver failure and life-threatening complications such as internal bleeding, infection, and hepatic encephalopathy.

1. Liver Cirrhosis Presented by: Dave Jay S. Manriquez RN.

9. Micronodular cirrhosis:

10. Alcoholic Hepatitis

11. Macronodular Cirrhosis

12. Nutmeg Liver-Cardiac Sclerosis

13. Prevalence of Liver Cirrhosis around the world

14. Normal Liver

15. Cirrhosis

25. Cirrhosis Clinical Features

27. Liver necrosis liver failure Liver fibrosis And scarring

28. Dec.androgen/ Estrogen p. Decrease ADH Dec.met.of CHON And Carb./ Dec.Fat bile Vit.k absop. hyperbilirubinemia Plasma CHON Bilirubin metabolism Bilirubin excretion In urine Clay-colored stool Dark urine jaundice Bleeding tendencies Spider angiomas Testicular atrophy Gyneco mastia Palmar Erythema Loss of Body hair Menstrual changes edema Hypoglycemia Acites Edema

29. Liver fibrosis Portal HPN ascites Anemia Thrombocytopenia leukopenia splenomegaly bleeding hemorrhoids Superficial Abdominal varices Esophageal varices edema infection Delayed Wound healing bleeding

30. Liver failure Inability to Metabolize ammonia Hepatic encephalopathy Confusion to Hepatic coma DEATH Increase serum ammonia Asterexis Respiratory acidosis Alterations In sleep Foul breath

31. Liver Biopsy – Cirrhosis

32. Liver Biopsy – Cirrhosis:

33. MRI Cirrhosis

35. Hepatocellular Carcinoma

37. Thank you and May God be Glorified