dina patho

1. Odontogenic tumor

2. Ameloblastoma.
A, Gross photograph of a mandibular resection specimen.
B, The radiograph of the specimen shows a large radiolucent
defect associated with an inferiorly displaced third molar.

3. Ameloblastoma
large expansile mass of the anterior mandible

5. Ameloblastoma: Destructive radiolucent lesion associated with
root resorption of the anterior teeth.

6. Ameloblastoma (follicular pattern). Multiple islands of odontogenic epithelium demonstrating
peripheral columnar differentiation with reverse polarization. The central zones resemble stellate
reticulum and exhibit foci of cystic degeneration.

7. Ameloblastoma (follicular pattern) . This high power photomicrograph highlights the
peripheral columnar cells exhibiting reverse polarization.

8. Ameloblastoma (plexiform pattern) . large anastomosing cords of
odontogenic epithelium. The high-power view(inset) reveals columnar cells
with reverse polarization.

9. • Ameloblastom a (acanthomatous pattern) Islands of
ameloblastoma demonstrating central squamous differentiation.

10. Ameloblastoma (granular cell variant). Tumor islands exhibiting
cells with prominent granular cytoplasm.

11. Ameloblastoma (desmoplastic variant). Thin cords of ameloblastic
epithelium within a dense fibrous connective tissue stroma.

12. Ameloblastoma (basal cell variant ). Island of hyperchromatic basaloid cells.

13. Unicystic ameloblastoma. A large radiolucency in a 7-year-old boy with displacement of the
developing second molar to the inferior border of the mandible. This was believed to be a
large dentigerous cyst.

15. Unicystic ameloblastoma (luminal type). The cyst is lined by ameloblastic
epithelium showing a hyperchromatic polarized basal layer. The overlying
epithelial cells are loosely cohesive and resemble stellate reticulum.

16. Unicystic ameloblastoma (intraluminal plexiform type). Photomicrograph of
the intraluminal mass arising from the cyst wall in the same patient shown in
The inset shows the intraluminal mass at higher magnification.

17. Unicystic ameloblastoma (mural type). Islands of follicular ameloblastoma
are infiltrating into the fibrous connective tissue wall.

19. Adenomatoid odontogenic tumor. A well circumscribed solid mass can be seen
enveloping the crown of this tooth.

20. Adenomatoid odontogenic tumor (follicular type) . Radiolucent lesion involving an
unerupted mandibular first premolar. Fine snowflake calcifications are present in the
radiolucent area. In contrast to the usual dentigerous cyst. the radiclucency
extends almost to the apex of the tooth.

21. Adenomatoid odontogenic tumor. Low-power view demonstrating a thick
capsule surrounding the tumor.

22. Adenomatoid odontogenic tumor. Higher magnification showing the duct
like epithelial structures. The nuclei of the columnar calls are polarized away
from the central spaces.

23. Calcifying epithelial odontogenic tumor. Honeycombed multilocular radiolucency
containing fine calcifications.

24. Calcifying epithelial odontogenic tumor. Sheets of polyhedral tumor cells with
prominent eosinophilic cytoplasm and intercellular bridging. Pools of
amorphous eosinophilic amyloid are present. Multiple lesegang ring
calcifications are seen in the inset

25. Squamous odontogenic tumor. Lucent defect extending along the roots of
the lateral incisor and first premolar teeth.

26. Squamous odontogenic tumor. Islands of bland appearing squamous epithelium in
a fibrous stroma. Microcyst formation is seen. The inset shows one of the tumor
islands at higher power.

27. Ameloblastic fibroma. Well-defined radiolucent defect associated
with an unerupted second molar.

28. Ameloblastic fibra-odontoma. Radiolucent defect in the ramus containing
small calcificat ions having the radiodensity of tooth structure.

29. Ameloblastic fibroma. long, narrow cords of odontogenic
epithelium in a richly cellular, primitive mesenchymal stroma. Note
the peripheral columnar differentiation (inset).

30. Ameloblastic fibre-odontoma. The soft tissue component of the tumor is
indistinguishable from an ameloblastic fibroma. Developing rudimentary tooth like
structures are shown (inset).

31. Ameloblastic fibrosarcoma. The cellular mesenchymal tissue shows hyperchromatism
and atypical cells.A small island of ameloblastic epithelium is present.

32. Compound odontoma Surgical specimen consisting of more than 20 malformed
tooth like structures.

33. Compound odontoma. Multiple tooth lets preventing the eruption of the
mandibular cuspid.

34. Complex odontoma. This decalcified section shows a disorganized mass of dentin
intermixed with small pools of enamel matrix.

35. Odontogenic fibroma. Apical radiolucent lesion in the incisor and premolar area.

36. Odontogenic fibroma (simple type). Scattered fibroblasts within a collagenous
background. No epithelial rests were found on multiple sections from this tumor.

37. Odontogenic fibroma (World Health Organization [WHO] type. A cellular
fibroblastic lesion containing narrow cords of odontogenic epithelium.

38. Granular cell odontogenic tumor. Radiolucent lesion involving the apical
area of endodontically treated maxillary teeth.

39. Granular cell odontogenic tumor. Sheet of large granular mesenchymal cells
with small nest s of odontogenic epithelium.

40. Odontogenic myxoma of the right mandible.

41. Odontogenic myxoma showing characteristic
multilocularity.

42. Odontogenic myxoma exhibiting typical bland myxoid appearance.

43. Odontogenic fibromyxoma with collagen bundles and residual bony
trabecula (center) evident.

44. Ameloblastic carcinoma. A, Rapidly growing tumor showing prominent labial
expansion of the mandible in the incisor and premolar area. B, The panoramic
radiograph shows irregular destruction of the mandible.

45. Ameloblastic carcinoma. Ameloblastlc epithelium demonstrating hyperchromatism.
pleomorphism, and numerousmitotic figures.

46. Clear cell odontogenic carcinoma. Tumor island demonstrating cells with a clear
cytoplasm. Note the peripheral columnar differentiation.