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How do I approach Infection Outbreak in PICU? Dr Farhan Shaikh Consultant Pediatric Intensivist Internal assessor for Quality Standards Rainbow Children’s Hospital Hyderabad
[object Object],[object Object],“ Acinetobacter outbreak”?
What is an Outbreak? ,[object Object],[object Object],[object Object],Surveillance!
Approach ,[object Object],[object Object],[object Object],[object Object],Management of the outbreak ,[object Object],[object Object],[object Object],[object Object]
Outbreak Investigation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Microbiological aspects ,[object Object],[object Object],[object Object],[object Object]
Case Definition should include.. ,[object Object],[object Object],[object Object],[object Object]
Example of case definitions ,[object Object],[object Object],[object Object]
Patient and Environmental Investigation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
The Action Plan
Patient education  ,[object Object]
Education & Increased Awareness amongst health care workers ,[object Object],[object Object],[object Object]
 
Hand Hygeine: ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
http://www.who.int/gpsc/5may/How_To_HandWash_Poster.pdf © World Health Organization 2009. All rights reserved., and  the 'How to Handrub', URL: http://www.who.int/gpsc/5may/How_To_HandRub_Poster.pdf © World Health Organization 2009. All rights reserved.'
http://www.who.int/gpsc/5may/How_To_HandWash_Poster.pdf © World Health Organization 2009. All rights reserved., and  the 'How to Handrub', URL: http://www.who.int/gpsc/5may/How_To_HandRub_Poster.pdf © World Health Organization 2009. All rights reserved.'
Masks ,[object Object],[object Object],[object Object]
Gowning ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Airline Industry ,[object Object],[object Object],[object Object]
Concept of using “Check list” ,[object Object],[object Object]
Concept of using “Bundles” ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sheet No:     Bundle Criteria Use a single column for each Ventilated patient. Mark the appropriate response in the box. Optimal answer Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7   Prevention of aspiration of contaminated secretions   Elevate head of bed 30-45 degrees                  Ventilator circuit drained before repositioning patient                    Prevention of bacterial colonization of oropharynx, stomach & sinuses   Hand hygiene performed before & after contact with ventilator circuit.      Yes/No               Condensate from ventilator circuit drained every 2-4 hours                  Oral suction devices rinsed after every use & stored in plastic covers                  Unit mouth care policy followed every 2-4 hrs                    
Reason if ventilator circuit condensate not drained D 1: Busy schedule D 2: Did not remember D 3: Bed non-functional Gowns worn before providing care to the patient whenever soiling from respiratory secretions observed                    Ventilator circuits & in-line suction catheters changed only if visibly soiled                  Did the patient develop VAP today as per the defined criteria?   Yes/No               Reason if Head end not elevated N 1: Pt unstable  N 4: Other (Add comment) N 2: Surgical restriction N 3: Raised ICT
Environmental and Infection Control Supports
[object Object],[object Object],[object Object],[object Object],[object Object]
Spaulding categorized the process as.. Critical items: Items entering body or vascular system Must be sterilized  by steam under pressure, dry heat , Or for heat sensitive items ETO  Semicritical :   Items in contact with mucosa or non-intact skin. Disinfection  by a high level disinfectant  (e.g. Gluteraldehyde) Spaulding EH. Chemical disinfection of medical and surgical materials. In: Lawrence C, Block SS, eds.  Disinfection, sterilization, and preservation. Philadelphia: Lea & Febiger, 1968:517-31.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
FUMIGATION ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],William A. Rutala, Ph.D., M.P.H.1,2, David J. Weber, M.D., M.P.H.1,2, and the Healthcare Infection Control Practices Advisory Committee (HICPAC) Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008 .CDC
[object Object],[object Object],[object Object],William A. Rutala, Ph.D., M.P.H.1,2, David J. Weber, M.D., M.P.H.1,2, and the Healthcare Infection Control Practices Advisory Committee (HICPAC) Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008 .CDC
Isolation and Cohorting
Isolation and Cohorting ,[object Object],[object Object]
Transmission based Precautions ,[object Object],[object Object],[object Object],Practical Guidelines for Infection Control in Health Care Facilities. SEARO Regional Publication No. 41 WPRO Regional Publication.WHO.2004
Contact precautions ,[object Object],[object Object],[object Object],[object Object]
Implement standard precautions. ,[object Object],[object Object],[object Object],[object Object]
Implement standard precautions. ,[object Object]
Airborne precautions ,[object Object],[object Object],Practical Guidelines for Infection Control in Health Care Facilities.  SEARO Regional Publication No. 41 WPRO Regional Publication.WHO.2004
Airborne precautions ,[object Object],[object Object],[object Object],[object Object]
Droplet precautions ,[object Object],[object Object],Practical Guidelines for Infection Control in Health Care Facilities. SEARO Regional Publication No. 41 WPRO Regional Publication.WHO.2004
Droplet precautions  ,[object Object],[object Object],[object Object]
Antimicrobial stewardship ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Universal Screening ,[object Object],[object Object],[object Object],[object Object],[object Object],Jane D. Siegel, MD; et al Management of Multidrug-Resistant Organisms In Healthcare  Settings, 2006 CDC
Focused Screening ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Jane D. Siegel, MD; et al Management of Multidrug-Resistant Organisms In Healthcare  Settings, 2006 CDC
[object Object],[object Object],[object Object],[object Object],[object Object]
Decolonization ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Jane D. Siegel, MD; et al Management of Multidrug-Resistant Organisms In Healthcare Settings, 2006 CDC
Scenario
In a 10 bedded PICU, there was an unusual increase incidence of  MRSA found by the Microbiology Dept  Outbreak investigation Screening of the patients  suspected to be part of  Outbreak Surveillance swabs  of Environment Core Competencies Education of pts & visitors Hand hygiene practices Education of Health Care  Workers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Emergency meeting called. Participants:  Infection control team, PICU Consultants, PICU nurse in-charge, Hospital administrator & House keeping
During environmental investigation, the  surveillance swab from ET end of AMBU bag isolated MRSA ,[object Object],[object Object],[object Object],Thorough auditing of whole sterilization & Disinfection procedure was made
[object Object],[object Object],[object Object],Subsequent surveillance swabs from articles did not show the MRSA ,[object Object],[object Object],[object Object]
THUS COMPLETING AUDIT CYCLE Audit: How to do in practice? BMJ 2008;336:1241-5
Administrative support ,[object Object],[object Object],[object Object],[object Object]
The formula to bring change!! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THANK YOU

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approaching infection outbreak in picu

  • 1. How do I approach Infection Outbreak in PICU? Dr Farhan Shaikh Consultant Pediatric Intensivist Internal assessor for Quality Standards Rainbow Children’s Hospital Hyderabad
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  • 17. http://www.who.int/gpsc/5may/How_To_HandWash_Poster.pdf © World Health Organization 2009. All rights reserved., and  the 'How to Handrub', URL: http://www.who.int/gpsc/5may/How_To_HandRub_Poster.pdf © World Health Organization 2009. All rights reserved.'
  • 18. http://www.who.int/gpsc/5may/How_To_HandWash_Poster.pdf © World Health Organization 2009. All rights reserved., and  the 'How to Handrub', URL: http://www.who.int/gpsc/5may/How_To_HandRub_Poster.pdf © World Health Organization 2009. All rights reserved.'
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  • 28. Sheet No:     Bundle Criteria Use a single column for each Ventilated patient. Mark the appropriate response in the box. Optimal answer Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7   Prevention of aspiration of contaminated secretions   Elevate head of bed 30-45 degrees                  Ventilator circuit drained before repositioning patient                    Prevention of bacterial colonization of oropharynx, stomach & sinuses   Hand hygiene performed before & after contact with ventilator circuit.     Yes/No               Condensate from ventilator circuit drained every 2-4 hours                  Oral suction devices rinsed after every use & stored in plastic covers                  Unit mouth care policy followed every 2-4 hrs                   
  • 29. Reason if ventilator circuit condensate not drained D 1: Busy schedule D 2: Did not remember D 3: Bed non-functional Gowns worn before providing care to the patient whenever soiling from respiratory secretions observed                    Ventilator circuits & in-line suction catheters changed only if visibly soiled                  Did the patient develop VAP today as per the defined criteria?   Yes/No               Reason if Head end not elevated N 1: Pt unstable N 4: Other (Add comment) N 2: Surgical restriction N 3: Raised ICT
  • 30. Environmental and Infection Control Supports
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  • 32. Spaulding categorized the process as.. Critical items: Items entering body or vascular system Must be sterilized by steam under pressure, dry heat , Or for heat sensitive items ETO Semicritical : Items in contact with mucosa or non-intact skin. Disinfection by a high level disinfectant (e.g. Gluteraldehyde) Spaulding EH. Chemical disinfection of medical and surgical materials. In: Lawrence C, Block SS, eds. Disinfection, sterilization, and preservation. Philadelphia: Lea & Febiger, 1968:517-31.
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  • 57. THUS COMPLETING AUDIT CYCLE Audit: How to do in practice? BMJ 2008;336:1241-5
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Notes de l'éditeur

  1. E.g. During outbreak of Surgical Site Infection (SSIs) caused by MRSA, a patient who is growing MSSA will be excluded
  2. One of the first task of the investigative team is to develop a working case definition based on the known facts of the outbreak.
  3. Any outbreak investigation must include close inspection of the environment mainly the inanimate objects.
  4. With adequate nursing staff, it is more likely that infection control practices will be given appropriate attention and applied correctly and consistently
  5. More than 30 years ago, Earle H. Spaulding devised a rational approach to disinfection and sterilization of patient-care items and equipment.14 This classification scheme is so clear and logical that it has been retained, refined, and successfully used by infection control professionals and others when planning methods for disinfection or sterilization. 1, 13, 15, 17, 19, 20
  6. Intact skin acts as an effective barrier to most microorganisms; therefore, the sterility of items coming in contact with intact skin is "not critical."
  7. patients should be moved for essential purposes only. If transportation is required, use precautions to minimize the risk of transmission.
  8. MRSA: Cultures of the nares identify most patients with MRSA and peri-rectal and wound cultures can identify additional carriers MDRO-GNB: peri-rectal or rectal swabs alone or in combination with oro-pharyngeal, endotracheal, inguinal, or wound cultures.
  9. Decolonization regimens are not sufficiently effective to warrant routine use. Therefore, most healthcare facilities have limited the use of decolonization to MRSA outbreaks, or other high prevalence situations, especially those affecting special-care units. Several factors limit the utility of this control measure on a widespread basis: 1) identification of candidates for decolonization requires surveillance cultures; 2) candidates receiving decolonization treatment must receive follow-up cultures to ensure eradication; and 3) recolonization with the same strain, initial colonization with a mupirocin-resistant strain, and emergence of resistance to mupirocin during treatment can occur(289, 303, 308-310). HCP implicated in transmission of MRSA are candidates for decolonization and should be treated and culture negative before returning to direct patient care. In contrast, HCP who are colonized with MRSA, but are asymptomatic, and have not been linked epidemiologically to transmission, do not require decolonization.