Dokumen tersebut memberikan informasi mengenai bahaya merokok bagi kesehatan dan lingkungan. Merokok dapat menyebabkan berbagai penyakit serius dan mengancam jiwa, serta mengurangi harapan hidup perokok hingga 10 tahun lebih cepat. Asap rokok juga berbahaya bagi orang lain dan dapat menyebabkan penyakit, sehingga perokok harus menghormati hak orang lain untuk bernafas udara bersih.
4. PROFAIL PEROKOK DI MALAYSIA Dunia (1995) Malaysia (2000) Lelaki 15 tahun keatas 921 juta (80%) 4.08 juta (90%) Perempuan 15 tahun keatas 236 juta (20%) 450 ribu (10%) Keseluruhan 15 tahun keatas 1,157 juta 4.53 juta
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6. PEROKOK MATI PURATA 10 TAHUN AWAL DARIPADA ORANG YANG TIDAK MEROKOK Doll R et al. BMJ . 2004;328:1519–1527. 4 26 59 81 94 100 80 60 40 20 0 40 50 60 70 80 90 100 Physicians Who Smoked Cigarettes Physicians Who Did Not Smoke Cigarettes 10 years 97 91 81 59 24 2 Years % Survival From Age 35
7. KESAN DARIPADA BERHENTI MEROKOK 35-44 60 50 40 Doll R et al. BMJ. 2004;328:1519–1527. 55-64 Years % Survival From Age 45-54 Stopped Age Nonsmokers Cigarette Smokers 35-44
10. ARSENIC Dalam racun semut AMMONIA Dalam pencuci lantai CADMIUM Dalam beteri kereta DDT Racun perosak NAFTALENA Dalam ubat gegat VINIL KLORIDA Untuk buat PVC HIDROGEN SIANIDA Racun untuk buat Kebuk gas
15. Pengharaman Merokok “ Dan belanjalah pada jalan Allah, dan janganlah anda mencampakkan diri ke jalan kebinasaan, dan berbuat baiklah sesungguhnya Allah sangat suka mereka yang melakukan kebaikan” (Surah Al-Baqarah:195).
18. Perbandingan Bahan dalam Asap Aliran Utama dan Asap Aliran Sisi Dadah nikotin Aseton Tar Hidrogen sianid Karbon monoksida Toluen Benzen Anilin Nitrosamin (bahan karsinogen) 2 kali ganda 2-5 kali ganda 3 kali ganda 4-6 kali ganda 5 kali ganda 6-8 kali ganda 10 kali ganda 30 kali ganda 50 kali ganda Asap Aliran Utama vs Asap Aliran Sisi
19. Kesan asap terhadap perokok pasif (Passive smoker) Asap rokok pasif mengakibatkan: 3,000 orang dewasa mati akibat kanser ini setiap tahun disebabkan oleh asap rokok pasif Menghidapi gangguan pernafasan bila terdedah kepada asap rokok Kanak-kanak sehingga usia 18 bulan adalah dua kali lebih mudah sakit jika ibubapa mereka hisap rokok KANSER PARU-PARU BRONKITIS DAN PNEUMONIA
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22. MENGAPA MEROKOK? Mild pleasant stimulation Binds to nACh receptors Increase in dopamine nicotine Positive Reinforcement
29. BERHENTI TANPA SOKONGAN Of the people that try to quit, 70% will try without help (‘Cold Turkey) The majority will relapse in the first week Only 2.5% abstinent at 1-year Of the people that try to quit, 70% will try without help (‘Cold Turkey) The majority will relapse in the first week
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31. PANDUAN “QUIT SMOKING” 1 Buat keputusan untuk berhenti merokok 2 Menetap jangkamasa untuk berhenti merokok 3 Menetapkan tarikh 4 Yakin diri 5 Buat nota peringatan 6 Katakan “aku bukan perokok ” 7 Sentiasa berfikiran positif 8 Dapatkan sokongan 9 Lawan keinginan untuk merokok 10 Gunakan terapi gantian nikotin 11 Dapatkan rawatan lanjut di klinik 12 Rancang kehidupan harian tanpa rokok
Key Point Results from a prospective study of 50 years’ of data published by Doll et al in 2004 demonstrated that, among approximately 35,000 male doctors in the United Kingdom, smoking decreased life expectancy by an average of 10 years in regular smokers versus those who had never smoked. References 1) Doll R, et al. Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ 2004;328:1519 Key Point Among physicians in the United Kingdom, current cigarette smokers died an average of 10 years earlier than lifelong nonsmokers. Background This prospective study by Doll and colleagues used periodically mailed questionnaires to investigate the impact of smoking and of quitting smoking on the overall mortality of 34,439 male doctors in the United Kingdom from 1951 to 2001. Survival curves for percentage survival from age 35 years for male physicians born in 1900–1930 revealed a 10-year shift in overall survival for those who continued smoking cigarettes vs lifelong nonsmokers. This means that, on average, participants who never smoked lived 10 years longer than those who were current smokers. By age 70 years, 81% of lifelong nonsmokers were alive vs 59% of continuing cigarette smokers. A mortality rate of approximately 75% was reached at age 80 years for smokers but was not reached until age 90 years for nonsmokers. Reference 1. Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ . 2004;328:1519–1527.
Key Point Results from a prospective study of 50 years’ of data published by Doll et al in 2004 demonstrated that an increase in life expectancy resulted from quitting smoking regardless of the age at which this happened; however, the sooner a smoker stopped the more significant this effect was. References 1) Doll R, et al. Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ 2004;328:1519 Key Point Although quitting smoking at any age increases life expectancy, quitting at a younger age is most beneficial. Background The prospective study by Doll and colleagues of 34,439 male doctors in the United Kingdom followed from 1951 to 2001 found that quitting smoking, even later in life, improves life expectancy. Smokers who quit at age 60 years gained at least 3 years of life. Quitting at a younger age increased the years of life gained. A smoker who quit at age 50 gained approximately 6 years of life expectancy, and those who quit at age 40 gained about 9 years. Smokers who quit before middle age gained approximately 10 years and had survival curves similar to individuals who had never smoked. Reference 1. Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ . 2004;328:1519–1527.
SOURCE: HCP SLIDE DECK PART 1 SLIDE 19
Key point NRT is available in a variety of formats to suit patient preference
Key Point Varenicline is indicated for smoking cessation in adults. Background Varenicline is indicated for smoking cessation in adults. When prescribing varenicline, physicians also should provide patients with advice and support concerning their attempt at quitting smoking, as smoking cessation therapies appear to be more likely to be successful in conjunction with behavioral interventions. Patients must choose a date to quit smoking and initiate varenicline treatment 1 – 2 weeks before this date. Varenicline should be taken with a full glass of water, with or without food, with titration according to the following schedule: an initial dose of one 0.5 mg tablet once daily for the first 3 days, then one 0.5 mg taken in the morning and one 0.5 mg tablet taken in the evening for the next four days up to day 7. After the first 7 days, the dose should be increased to one 1.0 mg tablet in the morning and one 1.0 mg tablet in the evening. Patients who cannot tolerate varenicline may have the dose lowered temporarily or permanently to 0.5 mg BID. Reference 1. Varenicline Summary of Product Characteristics. Pfizer Ltd, Sandwich, UK. 2006. Varenicline Summary of Product /p 2/¶6,7,9-11;Table Varenicline Summary of Product /p 2/¶6,7,9-11;Table
Key Point The percentage of participants who discontinued treatment due to AEs receiving varenicline treatment was 11.4% vs 9.7% receiving placebo. More study participants who received varenicline treatment experienced nausea (28.6%) compared with those who received placebo. Background Approximately 4000 individuals were exposed to varenicline during clinical trials for up to 1 year (average 84 days). In placebo-controlled trials, the treatment discontinuation rate due to AEs was comparable between treatment groups: 11.4% in patients who received varenicline 1.0 mg twice daily compared with 9.7% in those who received placebo. Reference 1. Varenicline Summary of Product Characteristics. Pfizer Ltd, Sandwich, UK. 2006. Varenicline Summary of Product doc/p.5/¶3,4,5 Varenicline Summary of Product doc/p.5/¶3,4,5 Varenicline Summary of Product doc/p.5 and 6 Table