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Dr lokesh kumar meena
Dept of Radiodignosis MGIMS ,
              Sevagram wardha
Incidence
 Testicular tumors are rare.


 1 – 2 % of all malignant tumors.


 Most common malignancy in men in the 15 to 35 year
 age group.

 Benign lesions represent a greater percentage of cases
 in children than in adults.
CLASSIFICATION
 I.    Primary Neoplasms of Testis.
       A.   Germ Cell Tumor.
       B.   Non-Germ Cell Tumor .

 II.   Secondary Neoplasms.

 III. Paratesticular Tumors.
Germ cell tumors
   1. Seminomas - 40%
                   (a) Classic Typical Seminoma
                   (b) Anaplastic Seminoma
                   (c) Spermatocytic Seminoma
   2. Embryonal Carcinoma - 20 - 25%
   3. Teratoma - 25 - 35%
                 (a) Mature
                 (b) Immature
   4. Choriocarcinoma - 1%
   5. Yolk Sac Tumour
Sex cord/ gonadal stromal tumors (5 to 10% )
 1. Specialized gonadal stromal tumor
        (a)     Leydig cell tumor
        (b)     sertoli cell tumor

   2. Gonadoblastoma

   3.   Miscellaneous Neoplasms
        (a) Carcinoid tumor
        (b) Tumors of ovarian epithelial sub
                                  types
II. SECONDARY NEOPLASMS OF TESTIS
 A.     Reticuloendothelial Neoplasms
 B.     Metastases
III.PARATESTICULAR NEOPLASMS
   A.   Adenomatoid
   B.   Cystadenoma of Epididymis
   C.   Desmoplastic small round cell tumor
   D.   Mesothelioma
   E.   Melanotic neuroectodermal
Classic Seminoma
 82-85% of seminomas
 Mostly men in 30’s
 Rarely occurs in adolescents or infants

 Clear cytoplasm, dense nucleus
 Synctiotrophoblasts in 10-15%
   Elevated B-HCG in 10%
   hCG up to 500 ng/ml
 Lymphocytes in 20%
Seminoma imaging….
 microcalcification
 A large mass in the testes. Mass is markedly
  hypoechoic and inhomogenous with irregular, poorly
  defined margins.
 On color doppler imaging, the mass shows increased
  vascularity and feeding vessels.
 These ultrasound images suggest a diagnosis of Germ
  cell tumour of the testes, probably a seminoma.
Seminoma.
Focal increase in vascular signal with irregular
branching.
Seminoma. (a) right testis demonstrates a hydrocele(arrow), diffuse
microlithiasis (arrowheads), and a homogeneous mass with no definite
normal testicular parenchyma.
(b) Doppler US image shows a generalized increase in testicular vascular
flow
This is another seminoma. On sonograms, a
seminoma is often more homogeneous than
nonseminomatous cancers
This is a seminoma. Sometimes epididymal
invasion can be noted on sonograms.
Non-seminomatous germ cell tumor.

USG shows a focal lesion having a heterogenous
echotexture with solid and cystic components (asterix)
heterogeneous echogenicity, and small cystic areas
Mixed germ cell tumor
 composed of two or more types of germ cell tumour.
  They are considered to be part of non-seminomatous
  germ cell tumours.
 Overall they account for over 10% of all testicular
  cancers
Mixed germ cell tumor

                  Partly solid and
                  partly cystic
                  testicular mass
                  that proved to
                  be a mixed
                  germ cell
                  tumor
Mixed germ cell tumor




Heterogeneous,predominantly hypoechoic mass, with scattered areas of
hypoechogenicity (arrowheads). Normal testicular parenchyma is
compressed peripherally by the tumor and contains diffuse microlithiasis
(arrow).
(b) Doppler US image shows normal peripheral vascularity with absence of
central flow.
This is a mixed germ cell tumor. Testicular cancers
can be ill-defined and subtle.
Malignant teratoma. A well defined hypoechoic
mass (open arrows) with a peripheral focus of
calcification (curved arrow).
Embryonal Carcinoma




Embryonal cell carcinoma with a vascularized tumor
with calcifications
Testicular choriocarcinoma
                Choriocarcinoma in a 16-
                year-old boy who presented
                with enlarged inguinal
                lymph nodes.
                 US image demonstrates a
                mixed solid and cystic mass
                in the left testis
                (arrowheads).
“Testicular choriocarcinoma with cannon-ball
metastases in lung.”
Dilated rete testes can mimic a cystic neoplasm, but
they are usually elongated on orthogonal views and
clearly located in the testicular mediastinum.
Testicular sarcoid can mimic seminoma when it
presents as a solid-appearing testicular mas
Leydig Cell Tumors of the Testis




a 27-year-old man with testicular discomfort. A, Sonogram showing
a homogeneously hypoechoic tumor in the anterior aspect of the
testis.
B, Power Doppler image showing circumferential blood flow around
the tumor.
Lymphoma and leukaemia
 most common metastatic testicular tumours.
 Primary testicular leukaemia is rare, but leukaemic
  infiltration is not uncommon in children. The testis
  may be a site for leukaemic cells during chemotherapy.
 The most frequent sonographic appearance is diffuse
  enlargement with hypoechogenicity. Hypervascularity
  is typical.
 Focal well-marginated masses have been described in
  chronic lymphocytic leukaemia.
left testis is large and hypoechoic compared to
the normal right testis.
Epididymitis.
Image of the testis demonstrates
enlarged, thickened, and heterogeneous epididymis.
Doppler shows an increase in vascular flow.
Testicular torsion
 (a) Longitudinal
 US scan of the right hemiscrotum shows a round
  supratesticular mass (M), which represents an edematous
  spermatic cord. There are several anechoic structures
  (arrowheads) within the mass, which probably represent
  obstructed and dilated lymphatic vessels.
 (b) Bilateral transverse color Doppler images show no
  color flow signals in the right testis, which is enlarged
  and has heterogeneous echogenicity. Reactive hydrocele
  (h) and thickening of the scrotal wall.
Varicocele.
 Multiple sepiginous ,tubular hypoechic structure of
    diameter more then 2mm.
   Generally seen posterior or lateral to the testis.
   More common on left side b/c of longer course of left
    testicular vein.
   Grading on USG (on valsalva)
   Grade 1 : 2-2.5 mm ,grade 2 : 2.5-3mm, grade 3 : 3mm
Varicocele.
Color Doppler demonstrates multiple serpentine
vascular channels within the scrotum, which
become more prominent after Valsalva maneuver.
Orchitis.
 Color Doppler of the scrotum reveals
 -hypoechoic testis with
-markedly increased vascularity,

compared with normal echogenic testis showing
normal vascularity.
Hematocele.
 One week following a direct blow to the scrotum, US
    reveals complex fluid with septation and debris indicative
    of hematocele in the cavity of the tunica vaginalis.
   The scrotal wall is thickened.
   Septations and loculations are common
   Pyocele has a similar appearance.
   Anechoic fluid without septations is characteristic of
    hydrocele .
   Bloody fluid contains low-intensity echoes that often layer.
Testicular
                                      Abscess




testis is swollen and has markedly heterogeneous
echogenicity.
A central complex fluid collection (arrow) was proven to
be an abscess
Spermatocele
 - Found only at the superior pole of the testis adjacent
    to the mediastinum.
   - Oval/round cystic mass with echogenic, often
    layering, fluid.
   - May appear solid if completely filled with echogenic
    fluid.
   - Septations are common.
   - Solitary, with size up to 2-3-cm diameter.
Large cystic extratesticular mass (S) with septations and
debris above the upper pole of the testis (T) is
characteristic for spermatocel
Testicular tumors

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Testicular tumors

  • 1. Dr lokesh kumar meena Dept of Radiodignosis MGIMS , Sevagram wardha
  • 2. Incidence  Testicular tumors are rare.  1 – 2 % of all malignant tumors.  Most common malignancy in men in the 15 to 35 year age group.  Benign lesions represent a greater percentage of cases in children than in adults.
  • 3. CLASSIFICATION  I. Primary Neoplasms of Testis.  A. Germ Cell Tumor.  B. Non-Germ Cell Tumor .  II. Secondary Neoplasms.  III. Paratesticular Tumors.
  • 4. Germ cell tumors  1. Seminomas - 40%  (a) Classic Typical Seminoma  (b) Anaplastic Seminoma  (c) Spermatocytic Seminoma  2. Embryonal Carcinoma - 20 - 25%  3. Teratoma - 25 - 35%  (a) Mature  (b) Immature  4. Choriocarcinoma - 1%  5. Yolk Sac Tumour
  • 5. Sex cord/ gonadal stromal tumors (5 to 10% ) 1. Specialized gonadal stromal tumor (a) Leydig cell tumor (b) sertoli cell tumor 2. Gonadoblastoma 3. Miscellaneous Neoplasms (a) Carcinoid tumor (b) Tumors of ovarian epithelial sub types
  • 6. II. SECONDARY NEOPLASMS OF TESTIS  A. Reticuloendothelial Neoplasms  B. Metastases III.PARATESTICULAR NEOPLASMS  A. Adenomatoid  B. Cystadenoma of Epididymis  C. Desmoplastic small round cell tumor  D. Mesothelioma  E. Melanotic neuroectodermal
  • 7. Classic Seminoma  82-85% of seminomas  Mostly men in 30’s  Rarely occurs in adolescents or infants  Clear cytoplasm, dense nucleus  Synctiotrophoblasts in 10-15%  Elevated B-HCG in 10%  hCG up to 500 ng/ml  Lymphocytes in 20%
  • 8. Seminoma imaging….  microcalcification  A large mass in the testes. Mass is markedly hypoechoic and inhomogenous with irregular, poorly defined margins.  On color doppler imaging, the mass shows increased vascularity and feeding vessels.  These ultrasound images suggest a diagnosis of Germ cell tumour of the testes, probably a seminoma.
  • 9. Seminoma. Focal increase in vascular signal with irregular branching.
  • 10. Seminoma. (a) right testis demonstrates a hydrocele(arrow), diffuse microlithiasis (arrowheads), and a homogeneous mass with no definite normal testicular parenchyma. (b) Doppler US image shows a generalized increase in testicular vascular flow
  • 11. This is another seminoma. On sonograms, a seminoma is often more homogeneous than nonseminomatous cancers
  • 12. This is a seminoma. Sometimes epididymal invasion can be noted on sonograms.
  • 13. Non-seminomatous germ cell tumor. USG shows a focal lesion having a heterogenous echotexture with solid and cystic components (asterix)
  • 14. heterogeneous echogenicity, and small cystic areas
  • 15. Mixed germ cell tumor  composed of two or more types of germ cell tumour. They are considered to be part of non-seminomatous germ cell tumours.  Overall they account for over 10% of all testicular cancers
  • 16. Mixed germ cell tumor Partly solid and partly cystic testicular mass that proved to be a mixed germ cell tumor
  • 17. Mixed germ cell tumor Heterogeneous,predominantly hypoechoic mass, with scattered areas of hypoechogenicity (arrowheads). Normal testicular parenchyma is compressed peripherally by the tumor and contains diffuse microlithiasis (arrow). (b) Doppler US image shows normal peripheral vascularity with absence of central flow.
  • 18.
  • 19. This is a mixed germ cell tumor. Testicular cancers can be ill-defined and subtle.
  • 20. Malignant teratoma. A well defined hypoechoic mass (open arrows) with a peripheral focus of calcification (curved arrow).
  • 21. Embryonal Carcinoma Embryonal cell carcinoma with a vascularized tumor with calcifications
  • 22. Testicular choriocarcinoma Choriocarcinoma in a 16- year-old boy who presented with enlarged inguinal lymph nodes. US image demonstrates a mixed solid and cystic mass in the left testis (arrowheads).
  • 23. “Testicular choriocarcinoma with cannon-ball metastases in lung.”
  • 24. Dilated rete testes can mimic a cystic neoplasm, but they are usually elongated on orthogonal views and clearly located in the testicular mediastinum.
  • 25. Testicular sarcoid can mimic seminoma when it presents as a solid-appearing testicular mas
  • 26. Leydig Cell Tumors of the Testis a 27-year-old man with testicular discomfort. A, Sonogram showing a homogeneously hypoechoic tumor in the anterior aspect of the testis. B, Power Doppler image showing circumferential blood flow around the tumor.
  • 27. Lymphoma and leukaemia  most common metastatic testicular tumours.  Primary testicular leukaemia is rare, but leukaemic infiltration is not uncommon in children. The testis may be a site for leukaemic cells during chemotherapy.  The most frequent sonographic appearance is diffuse enlargement with hypoechogenicity. Hypervascularity is typical.  Focal well-marginated masses have been described in chronic lymphocytic leukaemia.
  • 28. left testis is large and hypoechoic compared to the normal right testis.
  • 29. Epididymitis. Image of the testis demonstrates enlarged, thickened, and heterogeneous epididymis. Doppler shows an increase in vascular flow.
  • 31.  (a) Longitudinal  US scan of the right hemiscrotum shows a round supratesticular mass (M), which represents an edematous spermatic cord. There are several anechoic structures (arrowheads) within the mass, which probably represent obstructed and dilated lymphatic vessels.  (b) Bilateral transverse color Doppler images show no color flow signals in the right testis, which is enlarged and has heterogeneous echogenicity. Reactive hydrocele (h) and thickening of the scrotal wall.
  • 32. Varicocele.  Multiple sepiginous ,tubular hypoechic structure of diameter more then 2mm.  Generally seen posterior or lateral to the testis.  More common on left side b/c of longer course of left testicular vein.  Grading on USG (on valsalva)  Grade 1 : 2-2.5 mm ,grade 2 : 2.5-3mm, grade 3 : 3mm
  • 33. Varicocele. Color Doppler demonstrates multiple serpentine vascular channels within the scrotum, which become more prominent after Valsalva maneuver.
  • 34. Orchitis. Color Doppler of the scrotum reveals -hypoechoic testis with -markedly increased vascularity, compared with normal echogenic testis showing normal vascularity.
  • 35.
  • 36. Hematocele.  One week following a direct blow to the scrotum, US reveals complex fluid with septation and debris indicative of hematocele in the cavity of the tunica vaginalis.  The scrotal wall is thickened.  Septations and loculations are common  Pyocele has a similar appearance.  Anechoic fluid without septations is characteristic of hydrocele .  Bloody fluid contains low-intensity echoes that often layer.
  • 37.
  • 38. Testicular Abscess testis is swollen and has markedly heterogeneous echogenicity. A central complex fluid collection (arrow) was proven to be an abscess
  • 39. Spermatocele  - Found only at the superior pole of the testis adjacent to the mediastinum.  - Oval/round cystic mass with echogenic, often layering, fluid.  - May appear solid if completely filled with echogenic fluid.  - Septations are common.  - Solitary, with size up to 2-3-cm diameter.
  • 40. Large cystic extratesticular mass (S) with septations and debris above the upper pole of the testis (T) is characteristic for spermatocel