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Format
Format
1. Introduction & History
2. Relevant Anatomy, Physiology
3. Aetiology
4. Pathophysiology
5. Pathology
6. Classification
7. Clinical Features
8. Investigations
9. Management
10.Prevention
Introduction & History.
Introduction & History.
• Urethral strictures can result from
inflammatory, ischemic, or traumatic
processes.
• These processes lead to scar tissue
formation; scar tissue contracts and reduces
the caliber of the urethral lumen, causing
resistance to the antegrade flow of urine.
• The term urethral stricture generally refers
to the anterior urethra.
Aetiology
Aetiology
• Idiopathic
• Congenital/ Genetic
• Nutritional Deficiency/excess
• Traumatic
• Infections /Infestation
• Autoimmune
• Neoplastic (Benign/Malignant)
• Degenerative
• Iatrogenic
• Psychosomatic
Aetiology
• traumatic or iatrogenic
• Inflammatory or infectious-
gonococcal urethritis.
• Malignant
• Congenital
• Idiopathic
• Radiation
• Lichen sclerosus
Clinical Features
Clinical Features
• Demography
• Symptoms
• Signs
• Prognosis
• Complications
Demography
Demography
• 200 and 1200 cases per 100 thousand
people,
• dramatically increased within people over
55 years.
Symptoms
• decreased force of stream
• urinary retention
• incomplete emptying
• terminal dribbling,
• intermittency.
• urinary tract infections
History
History
• Similar complaints
• Urethral instrumentation/ operations
• UTIs
Signs
Signs
• Full bladder
• Scars on penis.
Prognosis
Prognosis
• Bad
• Need lifelong dilatations.
Investigations
• Laboratory Studies
– Routine
– Special
• Imaging Studies
• Tissue diagnosis
– Cytology
• FNAC
– Histology
Diagnostic Studies
Imaging Studies
• X-Ray
• USG
• CT
• Angiography
• MRI
• Endoscopy- cystourethroscopy.
• Nuclear scan
Imaging Studies
• Retrograde urethrogram
• Antegrade cystourethrogram
Retrograde urethrogram
Retrograde urethrogram
Retrograde urethrogram
Retrograde urethrogram
Differential Diagnosis
Differential Diagnosis
• BPH
• UTI
• Urolithiasis
Non Operative Therapy
Non Operative Therapy
• No medical therapy to treat urethral
stricture disease,
• However, urinary tract infections (UTIs)
should be adequately treated prior to
surgical intervention
Minimally invasive Therapy
Minimally invasive Therapy
• Urethral dilation
• Internal urethrotomy
• Permanent urethral stents
Operative Therapy
Operative Therapy
Urethroplasty
• Open Reconstruction
• Primary repair
• Free graft repair
• bladder, buccal, or rectal mucosa
• Full-thickness skin graft
• Pedicled skin flaps
• Skin island onlay flaps
• Hairless scrotal island flap
• Skin island tubularized flap
Prevention
BE KIND TO URETHRA
• Urethra is a delicate organ treat it with
kindness.
• Think 100 times before catheterizing.
• Don’t catheterize for dubious reasons
• Choose SPC over urethral catheterization.
Guidelines
• In 2016, the American Urology Association
(AUA) released guidelines for the diagnosis
and treatment of male urethral strictures-
https://emedicine.medscape.com/article/45090
3-guidelines
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Urethral stricture.pptx

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