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Notes de l'éditeur
Figure 3. Pathological Features of Peripheral Blood and Bone Marrow in Patients with Myelofibrosis with Myeloid Metaplasia. Panel A shows myelophthisis of the blood. Immature granulocyte precursors, a nucleated red cell, and teardrop-shaped red cells are visible (Wright-Giemsa, x200). Biopsy specimens of the bone marrow core show stromal stranding and atypical megakaryocytes (Panel B; hematoxylin and eosin, x128), collagen fibrosis on silver-impregnation staining of reticulin (Panel C, x128), and thickening of the bone trabeculae (osteosclerosis) and intramedullary sinusoidal hematopoiesis (Panel D; hematoxylin and eosin, x128).