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NEURO-­‐CELLULITE	
  
  TREATMENT	
  
LIPO-STRESS
              NEURO-LIPOLYSIS STIMULATION
STRESS = the bane of the
century
➥ It upsets:
      ✓ our behavior
      ✓ the body metabolism.

It causes skin reactions:
    ◆ Overreacting skin,

    ◆ Nerve blockage,

    ◆ High blood pressure,

    ◆ Poor elimination,

    ◆ General or localized fat

      storage.
NEURO-COSMETICS
New scientific technology:
   ➥ demonstrates interactions between
      the nervous system and the skin
      through neurotransmitters.


Neurotransmitters:
   ◆ Regulate messages sent from the brain,
   ◆	
  Relay nerve impulse.


Neuro-cosmetics is the perfect partner for
neuro-aesthetics techniques, such as:
     ✓ Acupuncture
     ✓ Acupressure
   ➥ Increase of β-endorphins, pain-killer
      molecules.
LIPO-STRESS
            NEURO-LIPOLYSIS STIMULATION
A new generation slimming treatment.

A DUAL ACTION
● In skin upper layers 

✓ Increases the production of β-endorphins
      → Releases tensions
      → Eases elimination of fat deposits
● In skin deeper layers  
✓Improves the innervation of adipose tissue
       → Relieves congestion of adipocytes

LIPO-STRESS ACTIONS:
   ◆ Relieves painful localized cellulite

   ◆ Decreases stress in body prone to fat retention.
 
IN THE UPPER
LAYERS OF
THE SKIN
RELATIONSHIP BETWEEN SKIN STRESS AND CELLULITE

●   Due to the release of neurotransmitters,
    the skin nervous system controls:

                  ✓ Cell proliferation and differentiation:
                    keratinocytes, adipocytes
                  ✓ Production of neurotransmitters
                  ✓ Activation of immune cells.

                      ➡ BUT stress upsets the fragile balance
                         of the skin neuromodulators:
                      ➪ Eases fat storage
                      ➪ Limits fat release.
SOLUTION: ENDORPHINS TO FEND OFF STRESS

• Endorphins: specific neurotransmitters produced by
  nerve endings and keratinocytes.
➔ ANTI-STRESS, pain-killer effect, feeling of well-being.

• Due to relaxation:
  ✓ Lipogenesis resulting from stress
    decreases
  ✓ Lipolysis is triggered.

 ➠ Cellulite is reduced
 ➠ Orange peel skin is improved.

• You feel better about yourself
  ➔ the downward spiral generated by stress is
     discontinued.
NEUROCOSMETICS: RELEASE OF β-ENDORPHINS

       BETAPHROLINE: new patented neurocosmetic active
       ingredient of plant origin.


• Tephrosia purpurea extract: plant
  native to the tropical regions of
  India, Africa and Sth America.

• BETAPHROLINE stimulates the
  release of ß-endorphins by
  keratinoyctes.
	
  
BETAPHROLINE IN VITRO TEST
     STIMULATION OF THE RELEASE OF ß-ENDORPHINS
                    BY KERATINOCYTES
Test carried out on a culture of human keratinocytes
incubated for 24 hours.




                                         +163%
                                        Increase of
                                       β-endorphins

                                       ➥ANTI-STRESS
                                         ACTION
BETAPHROLINE: STIMULATION OF LIPOLYSIS
• Numerous enzymatic reactions occur
  within adipocytes resulting in:
  ➔ either lipogenesis
  ➔ or lipolysis.


• In vitro tests demonstrate
  the efficacy of
  BETAPHROLINE:

➠ To stimulate lipolysis
➠ To reduce lipogenesis.
BETAPHROLINE: STIMULATION OF cAMP
 • Lipolysis requires a particular messenger: cyclic AMP,
(cAMP) Adenosine Mono Phosphate derived from ATP.

cAMP is stimulated by an enzyme: adenylyl cyclase.



                                           + 85 %
                                        Activation of
                                    ADENYLYL CYCLASE
                                         ➥ Increase
                                          in lipolysis
                                               	
  
BETAPHROLINE: INHIBITION OF LIPOGENESIS
• Lipogenesis is activated in adipocytes by the enzyme
  Glycerol-3-Phosphate Di-Hydrogenase or G3PDH
  ➠ Storage of carbs into triglycerides.


                                   INHIBITION of G3PDH
                                  due to BETAPHROLINE:

                                        -  60 %
                                      ➥ Decrease in
                                       Lipogenesis
                                      ➥ Activation
                                        of lipolysis
AQ-PRESS RELIEVES TENSION POINTS AND
             STIMULATES β-ENDORPHINS

• AQ-PRESS: ACUPRESSURE device using VIBRATIONS
      ➠ Release of ß-endorphins.

• AQ-PRESS provides:
  ✓ a thorough body relaxation
  ✓ a relief of tensions.




• Combined with the LIPO-STRESS
  treatment protocol:

        ➠ EASES THE SLIMMING PROCESS.
 	
  
AQ-PRESS RELIEVES TENSION POINTS AND
     STIMULATES β-ENDORPHINS


               • AQ-PRESS:

                ACUPRESSURE of ACUPUNCTURE
                    points on the body:

               ➔ Restores energy flow
               ➔ Strengthens body metabolism
               ➔ Improves well-being.
ON THE
DEEPER
LAYERS
OF THE SKIN	
  
NERVOUS SYSTEM: NEURON
A neuron has a cell body with profusely branching
extensions extruding from it.
✓ Dendrites →
  receive and convey messages or nerve impulse
  coming from other nerve cells, to the cell body of
  the neuron.
✓ The axon → transmits
  signals (nerve impulse)
  to the other cells of the
  body.

The transmission of nerve
impulse takes place through
different neurotransmitters.
THE DEEP CUTANEOUS NERVOUS SYSTEM
Skin nerves answer to stimuli coming from:
        • Blood circulation
        • Emotional stress.
Due to the production of chemical modulators, they
can process information within the skin regarding:	
  

✓ Vasomotion,
✓ Thermoregulation,
✓ Secretion of glands
  and cells such as
  fibroblasts, adipocytes
✓ Tissue growth and
  differentiation.
THE DEEP CUTANEOUS NERVOUS SYSTEM
• In the skin, neuromodulators such as endorphins are
  produced by:
    ✓ Skin nerve fibers,
    ✓ Keratinocytes,
    ✓ Fibroblasts.

• Keratinocytes, fibroblasts
  and adipocytes CAN
  also synthesize:

    → growth factors.
SKIN GROWTH FACTORS
• Specific proteins that:
  ✓Participate in the
   proliferation of different
   cell types
  ✓Exert numerous functions
   in the development of the
   body.

• Rita Levi-Montalcini won the Nobel Prize in Medicine
  in 1986 for the discovery of the Nerve Growth Factor,
  NGF.
• NGF: the 1st growth factor that has been discovered.
• Since then, various growth factors have been
  identified: the epidermal growth factor (EGF), the fibroblast
  growth factor (FGF), etc.
NGF: NERVE GROWTH FACTOR

• NGF:
  ✓Facilitate the growth of nerve extensions
  ✓ Keep neuron alive
  ✓ Work on ADIPOCYTE functioning.


    They are produced in limited quantities.


         ➤ COMPETITION BETWEEN NEURONS

 ➥ Neurons without NGF stimulation disappear by
   apoptosis or process of programmed cell death.	
  
GROWTH FACTOR AND CELLULITE

• Development of cellulite:
     ✓ Hypertrophy of adipocytes
     ✓ Disruption:
            ◆ of innervation

            ◆ of blood and lymph circulation.



• Cell aging

➥ Causes a decrease of NGF
  synthesis.

➥ Hinders communication
  between cells.
GROWTH FACTOR AND CELLULITE
     NEW PATHWAY IN THE FIGHT AGAINST CELLULITE

Protecting neurons by
NGF helps:

◆   Stimulate lipolysis
◆   Reduce lipogenesis
◆   Prevent tissue hypoxia
    and oxidative stress,
    ➤ which triggers fat
       storage.
GROWTH FACTOR AND CELLULITE
Statement in laboratory:
    • Optimum innervation of the adipose tissue,
    • The more NGF,
           ⇒ the easier the lipolysis process.
GROWTH FACTOR AND CELLULITE
RESULTS:
          ⇒ The NGF is in direct contact with adipocytes: no effect on
lipolysis
          ⇒ Low innervation of the adipose tissue with the NGF
triggers a slight increase in lipolysis: + 32%
          ⇒ Optimal innervation of the adipose tissue with the NGF
triggers a significant increase in lipolysis: +117%




             OPTIMUM INNERVATION RESULTS IN
                   OPTIMAL LIPOLYSIS	
  
GLUTRAPEPTIDE: NEUROPROTECTION & NEUROLIPOLYSIS
 Our research laboratories have developed a new active ingredient
 for NEUROPROTECTION: GLUTRAPEPTIDE derived from biotechnology.
  
 GLUTRAPEPTIDE: NGF-LIKE
        ➤ Activates innervation of adipose tissue
        ➤ Potentializes the neuron answer to the NGF
        ➤ Protects deep nerve endings
        ➤ Stimulates optimum lipolysis by acting on the length of
           nerve fibers (neurite).




      GLUTRAPEPTIDE helps reach optimal innervation characterized
           by an average length of neurite of more than 20%	
  
GLUTRAPEPTIDE: OPTIMIZATION OF LIPOLYSIS
Acting on neurons, GLUTRAPEPTIDE increases:
       ➤ Their survival rate
       ➤ Their metabolic activity
       ➤ Their ability to optimize lipolysis.

                                    GLUTRAPEPTIDE increases
                                    the release of glycerol by
                                                51%	
  
FIRMING EFFECT OF GLUTRAPEPTIDE
IN VIVO TEST:
GLUTRAPEPTIDE potentializes the action of the NGF on:
     ✓ Fibroblast contraction
     ✓ Collagen fibers
          ⇒ IMMEDIATE TIGHTENING EFFECT
          ⇒ LONG TERM EFFECT: FIRMER SKIN WITH MORE TONE

                                            Increase in lipolysis:

                                                - 4 cm in arm
                                                - 6 cm in hip
                                                - 3.5 cm in thigh
                                               circumference



    GLUTRAPEPTIDE improves skin firmness, elasticity and
                density after only 28 days	
  
LIPO-STRESS,
A TREATMENT
FOR CELLULITE
 OF NERVOUS
    ORIGIN	
  
PROFESSIONAL SALON PRODUCTS
HOME CARE PRODUCTS
LIPO-GUM
                        SLIMMING EXFOLIATION
INDICATION
   Quickly eliminates dead cells. Activates microcirculation, provides better
    tissue oxygenation, stimulates the release of β-endorphins.
DIRECTIONS FOR USE
   Apply all over the body and carry out a message using circular
    movements. Rinse with hot towels. See our professional protocol.
INGREDIENTS
 GLUTRAPEPTIDE: stimulates neurolipolysis
 BETAPHROLINE: stimulates the release of β-endorphins

 ELEUTHERO: toning, rich in vitamins B

 WAKAMINE: lightens the skin

 PINEAPPLE: draining

 GRAPEFRUIT: toning, anti-elastase



    PRESENTATION
   Retail: not available
   Professional use: 400-ml pot - Ref. E882
SOLUTION NEUROLYSE

INDICATION
   Strengthens skin neuroprotection, stimulates

  neurolipolysis.
DIRECTIONS FOR USE
   Apply on cellulite areas.

   See professional protocol.




INGREDIENTS
 GLUTRAPEPTIDE: stimulates neurolipolysis
 BETAPHROLINE: stimulates the release of β-endorphins

 PALMARIA PALMATA: vein protector, draining

 SVELTONYL: inhibits phosphodiesterase, draining


    PRESENTATION
   Retail: not available
   Professional use: 500-ml bottle Ref. E883
LIPO-MASSAGE ZEOLITHE
                     THERMO-RELAXING ACTION

INDICATION
   Optimal body relaxation, helps the absorption of
    slimming ingredients due to the warm sensation
    produced upon application.

DIRECTIONS FOR USE
   Perform a relaxing massage to tense areas and knead
    areas with cellulite.


INGREDIENTS
 GREEN TEA: lipolytic
 GUARANA: stimulates lipolysis

 MATE: lipolytic

 PASSIFLORA: vein protector


PRESENTATION
 Retail: not available
 Professional use: 500-ml bottle – Ref. E884
FLUIDE DESTRESS
        STRONG SKIN NEUROPROTECTOR
             INDICATION
            Stimulates anti-stress receptors due to the release of
             β-endorphins.
         DIRECTIONS FOR USE
            Mix DESTRESS FLUID with NEUROLYSIS SERUM in the DESTRESS
             bottle. Give it a lengthy shake. Apply morning and evening
             to cellulite areas. See professional protocol.
             INGREDIENTS
              GLUTRAPEPTIDE: stimulates neurolipolysis
              BETAPHROLINE: stimulates the release of β-endorphins

-             WHITE TEA: lipolytic, anti-inflammatory, antioxidant
              TAMANU OIL: vein protector

              KIMARINE: antioxidant



    PRESENTATION
       Retail: 150-ml bottle - Ref. E879 in box - Ref. E881
       Professional use: 200-ml tube - Ref. E885
NEUROLYSE SERUM
                  STRONG SKIN NEUROPROTECTOR

 INDICATION
 Smoothing effect on unsightly cellulite dimpling.




 DIRECTIONS FOR USE
 Mix DESTRESS FLUID with NEUROLYSE SERUM in the

 DESTRESS bottle. Give it a lengthy shake. Apply
  morning and evening to cellulite areas.

 INGREDIENTS
PALMARIA PALMATA: vein protector, draining
 SVELTONYL: inhibits phosphodiesterase, draining


 PRESENTATION
   Retail: 10-ml bottle - Ref. E880 in box Ref. E881
   Professional use: not available
SALON TREATMENT PROTOCOL
                                              INDICATION
                        A new-generation slimming treatment
                         
          Dual action on neuromodulators, on the surface and deep down
                           Release of relaxing molecules.


                                        DANGER	
  WARNING!	
  
               DO	
  NOT	
  USE	
  THE	
  ELECTRIC	
  BLANKET	
  IN	
  THIS	
  TREATMENT	
  
                 AT	
  THE	
  SAME	
  TIME	
  AS	
  THE	
  ALUMINIUM	
  FOIL	
  SHEET.	
  
               NB.	
  This	
  treatment	
  can	
  be	
  carried	
  out	
  without	
  a	
  shower. 	
  

                             PREPARING THE TREATMENT BED

   WITH AN ELECTRIC BLANKET                                   WITHOUT AN ELECTRIC BLANKET
Open out the blanket and cover it                               Open out the SLIM EXPRESS
    with a plastic sheet E07.                                     ALUMINIUM FOIL E602

        Lay a large towel                                    Lay a large towel to prevent the
         (client comfort)                                   skin from sticking to the sheet and
                                                               reduce the rustle of the sheet
  Lay another plastic sheet E07                                       Lay a plastic sheet E07
   folded in half for the scrub                                     folded in half for the scrub
SALON TREATMENT PROTOCOL
EXFOLIATION
FRONT / BACK
Proceed with a complete scrub of the front of
the body with LIPO-GUM E882.
Make alternating movements until complete
elimination of the product. Shower is not necessary.

Proceed with a scrub on the back.
Once the scrub is over, remove the plastic sheet.


RELEASING TENSIONS
BACK
Using one AQ-PRESS E886
device in each hand,
position them on the
acupuncture points as shown in the diagrams here opposite
and press firmly on the handles to make the devices vibrate.
Each pressure should last at least 10 seconds.
From the feet moving upwards to the shoulders.
SALON TREATMENT PROTOCOL

APPLYING E883 SOLUTION NEUROLYSE
BACK
Apply on the cellulite areas.




THERMO-RELAXING MASSAGE
BACK
Carry out a long massage with
ZEOLITE LIPO-MASSAGE E884 all over the body.
During the massage, add a blob of product regularly
to boost the thermo-heating effect.
Apply a thick layer of ZEOLITE LIPO-MASSAGE E884.

The client turns over. Repeat steps 2, 3 and 4 on the front side.
SALON TREATMENT PROTOCOL
BODY WRAP
Cover the client with the SLIM EXPRESS E602
aluminium sheet or the PLASTIC SHEET E07 for 20min.
Clean the skin with hot towels or a shower.



Reminder: you can use an electric blanket instead of the aluminium sheet.
Danger warning: Do not use the aluminium SLIM EXPRESS (E602) together with he
electric blanket.
In this case, replace with a plastic sheet (E07).



END OF TREATMENT MASSAGE
FRONT / BACK
Apply DESTRESS FLUID E885 all over the body.




                       LENGTH OF TREATMENT = 1HR 15MIN.
                             8-SESSION TREATMENT
                          FREQUENCY = TWICE A WEEK
LIPO-STRESS
                  NEURO-LIPOLYSE STIMULATION
            LIPO-STRESS : A new-generation slimming treatment
                           A DUAL ACTION
 ● In the upper skin layers: BETAPHROLINE

     ✓ Increases the production of β-endorphins
              → Relieves tensions
              → Helps the elimination of fat:	
  stimulation of
Adenylyl cyclase by 85%.

 ● In the deeper skin layers: GLUTRAPEPTIDE
      ✓Improves innervation of adipose tissue
            → Relieves congestion of adipocytes
LIPOLYSIS GENERATED BY NEURONS IS STIMULATED BY 51%

LIPO-STRESS ACTIONS:
     ◆   Relieve painful localized cellulite
     ◆   Decrease stress in body prone to fat retention.
NEURO-­‐CELLULITE	
  	
  
  TREATMENT	
  

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Cellulite behandeling LIPO STRESS

  • 1. NEURO-­‐CELLULITE   TREATMENT  
  • 2. LIPO-STRESS NEURO-LIPOLYSIS STIMULATION STRESS = the bane of the century ➥ It upsets: ✓ our behavior ✓ the body metabolism. It causes skin reactions: ◆ Overreacting skin, ◆ Nerve blockage, ◆ High blood pressure, ◆ Poor elimination, ◆ General or localized fat storage.
  • 3. NEURO-COSMETICS New scientific technology: ➥ demonstrates interactions between the nervous system and the skin through neurotransmitters. Neurotransmitters: ◆ Regulate messages sent from the brain, ◆  Relay nerve impulse. Neuro-cosmetics is the perfect partner for neuro-aesthetics techniques, such as: ✓ Acupuncture ✓ Acupressure ➥ Increase of β-endorphins, pain-killer molecules.
  • 4. LIPO-STRESS NEURO-LIPOLYSIS STIMULATION A new generation slimming treatment. A DUAL ACTION ● In skin upper layers  ✓ Increases the production of β-endorphins → Releases tensions → Eases elimination of fat deposits ● In skin deeper layers   ✓Improves the innervation of adipose tissue → Relieves congestion of adipocytes LIPO-STRESS ACTIONS: ◆ Relieves painful localized cellulite ◆ Decreases stress in body prone to fat retention.
  • 6. RELATIONSHIP BETWEEN SKIN STRESS AND CELLULITE ● Due to the release of neurotransmitters, the skin nervous system controls: ✓ Cell proliferation and differentiation: keratinocytes, adipocytes ✓ Production of neurotransmitters ✓ Activation of immune cells. ➡ BUT stress upsets the fragile balance of the skin neuromodulators: ➪ Eases fat storage ➪ Limits fat release.
  • 7. SOLUTION: ENDORPHINS TO FEND OFF STRESS • Endorphins: specific neurotransmitters produced by nerve endings and keratinocytes. ➔ ANTI-STRESS, pain-killer effect, feeling of well-being. • Due to relaxation: ✓ Lipogenesis resulting from stress decreases ✓ Lipolysis is triggered. ➠ Cellulite is reduced ➠ Orange peel skin is improved. • You feel better about yourself ➔ the downward spiral generated by stress is discontinued.
  • 8. NEUROCOSMETICS: RELEASE OF β-ENDORPHINS BETAPHROLINE: new patented neurocosmetic active ingredient of plant origin. • Tephrosia purpurea extract: plant native to the tropical regions of India, Africa and Sth America. • BETAPHROLINE stimulates the release of ß-endorphins by keratinoyctes.  
  • 9. BETAPHROLINE IN VITRO TEST STIMULATION OF THE RELEASE OF ß-ENDORPHINS BY KERATINOCYTES Test carried out on a culture of human keratinocytes incubated for 24 hours. +163% Increase of β-endorphins ➥ANTI-STRESS ACTION
  • 10. BETAPHROLINE: STIMULATION OF LIPOLYSIS • Numerous enzymatic reactions occur within adipocytes resulting in: ➔ either lipogenesis ➔ or lipolysis. • In vitro tests demonstrate the efficacy of BETAPHROLINE: ➠ To stimulate lipolysis ➠ To reduce lipogenesis.
  • 11. BETAPHROLINE: STIMULATION OF cAMP • Lipolysis requires a particular messenger: cyclic AMP, (cAMP) Adenosine Mono Phosphate derived from ATP. cAMP is stimulated by an enzyme: adenylyl cyclase. + 85 % Activation of ADENYLYL CYCLASE ➥ Increase in lipolysis  
  • 12. BETAPHROLINE: INHIBITION OF LIPOGENESIS • Lipogenesis is activated in adipocytes by the enzyme Glycerol-3-Phosphate Di-Hydrogenase or G3PDH ➠ Storage of carbs into triglycerides. INHIBITION of G3PDH due to BETAPHROLINE: -  60 % ➥ Decrease in Lipogenesis ➥ Activation of lipolysis
  • 13. AQ-PRESS RELIEVES TENSION POINTS AND STIMULATES β-ENDORPHINS • AQ-PRESS: ACUPRESSURE device using VIBRATIONS ➠ Release of ß-endorphins. • AQ-PRESS provides: ✓ a thorough body relaxation ✓ a relief of tensions. • Combined with the LIPO-STRESS treatment protocol: ➠ EASES THE SLIMMING PROCESS.  
  • 14. AQ-PRESS RELIEVES TENSION POINTS AND STIMULATES β-ENDORPHINS • AQ-PRESS: ACUPRESSURE of ACUPUNCTURE points on the body: ➔ Restores energy flow ➔ Strengthens body metabolism ➔ Improves well-being.
  • 16. NERVOUS SYSTEM: NEURON A neuron has a cell body with profusely branching extensions extruding from it. ✓ Dendrites → receive and convey messages or nerve impulse coming from other nerve cells, to the cell body of the neuron. ✓ The axon → transmits signals (nerve impulse) to the other cells of the body. The transmission of nerve impulse takes place through different neurotransmitters.
  • 17. THE DEEP CUTANEOUS NERVOUS SYSTEM Skin nerves answer to stimuli coming from: • Blood circulation • Emotional stress. Due to the production of chemical modulators, they can process information within the skin regarding:   ✓ Vasomotion, ✓ Thermoregulation, ✓ Secretion of glands and cells such as fibroblasts, adipocytes ✓ Tissue growth and differentiation.
  • 18. THE DEEP CUTANEOUS NERVOUS SYSTEM • In the skin, neuromodulators such as endorphins are produced by: ✓ Skin nerve fibers, ✓ Keratinocytes, ✓ Fibroblasts. • Keratinocytes, fibroblasts and adipocytes CAN also synthesize: → growth factors.
  • 19. SKIN GROWTH FACTORS • Specific proteins that: ✓Participate in the proliferation of different cell types ✓Exert numerous functions in the development of the body. • Rita Levi-Montalcini won the Nobel Prize in Medicine in 1986 for the discovery of the Nerve Growth Factor, NGF. • NGF: the 1st growth factor that has been discovered. • Since then, various growth factors have been identified: the epidermal growth factor (EGF), the fibroblast growth factor (FGF), etc.
  • 20. NGF: NERVE GROWTH FACTOR • NGF: ✓Facilitate the growth of nerve extensions ✓ Keep neuron alive ✓ Work on ADIPOCYTE functioning. They are produced in limited quantities. ➤ COMPETITION BETWEEN NEURONS ➥ Neurons without NGF stimulation disappear by apoptosis or process of programmed cell death.  
  • 21. GROWTH FACTOR AND CELLULITE • Development of cellulite: ✓ Hypertrophy of adipocytes ✓ Disruption: ◆ of innervation ◆ of blood and lymph circulation. • Cell aging ➥ Causes a decrease of NGF synthesis. ➥ Hinders communication between cells.
  • 22. GROWTH FACTOR AND CELLULITE NEW PATHWAY IN THE FIGHT AGAINST CELLULITE Protecting neurons by NGF helps: ◆ Stimulate lipolysis ◆ Reduce lipogenesis ◆ Prevent tissue hypoxia and oxidative stress, ➤ which triggers fat storage.
  • 23. GROWTH FACTOR AND CELLULITE Statement in laboratory: • Optimum innervation of the adipose tissue, • The more NGF, ⇒ the easier the lipolysis process.
  • 24. GROWTH FACTOR AND CELLULITE RESULTS: ⇒ The NGF is in direct contact with adipocytes: no effect on lipolysis ⇒ Low innervation of the adipose tissue with the NGF triggers a slight increase in lipolysis: + 32% ⇒ Optimal innervation of the adipose tissue with the NGF triggers a significant increase in lipolysis: +117% OPTIMUM INNERVATION RESULTS IN OPTIMAL LIPOLYSIS  
  • 25. GLUTRAPEPTIDE: NEUROPROTECTION & NEUROLIPOLYSIS Our research laboratories have developed a new active ingredient for NEUROPROTECTION: GLUTRAPEPTIDE derived from biotechnology.   GLUTRAPEPTIDE: NGF-LIKE ➤ Activates innervation of adipose tissue ➤ Potentializes the neuron answer to the NGF ➤ Protects deep nerve endings ➤ Stimulates optimum lipolysis by acting on the length of nerve fibers (neurite). GLUTRAPEPTIDE helps reach optimal innervation characterized by an average length of neurite of more than 20%  
  • 26. GLUTRAPEPTIDE: OPTIMIZATION OF LIPOLYSIS Acting on neurons, GLUTRAPEPTIDE increases: ➤ Their survival rate ➤ Their metabolic activity ➤ Their ability to optimize lipolysis. GLUTRAPEPTIDE increases the release of glycerol by 51%  
  • 27. FIRMING EFFECT OF GLUTRAPEPTIDE IN VIVO TEST: GLUTRAPEPTIDE potentializes the action of the NGF on: ✓ Fibroblast contraction ✓ Collagen fibers ⇒ IMMEDIATE TIGHTENING EFFECT ⇒ LONG TERM EFFECT: FIRMER SKIN WITH MORE TONE Increase in lipolysis: - 4 cm in arm - 6 cm in hip - 3.5 cm in thigh circumference GLUTRAPEPTIDE improves skin firmness, elasticity and density after only 28 days  
  • 31. LIPO-GUM SLIMMING EXFOLIATION INDICATION  Quickly eliminates dead cells. Activates microcirculation, provides better tissue oxygenation, stimulates the release of β-endorphins. DIRECTIONS FOR USE  Apply all over the body and carry out a message using circular movements. Rinse with hot towels. See our professional protocol. INGREDIENTS  GLUTRAPEPTIDE: stimulates neurolipolysis  BETAPHROLINE: stimulates the release of β-endorphins  ELEUTHERO: toning, rich in vitamins B  WAKAMINE: lightens the skin  PINEAPPLE: draining  GRAPEFRUIT: toning, anti-elastase PRESENTATION  Retail: not available  Professional use: 400-ml pot - Ref. E882
  • 32. SOLUTION NEUROLYSE INDICATION  Strengthens skin neuroprotection, stimulates neurolipolysis. DIRECTIONS FOR USE  Apply on cellulite areas.  See professional protocol. INGREDIENTS  GLUTRAPEPTIDE: stimulates neurolipolysis  BETAPHROLINE: stimulates the release of β-endorphins  PALMARIA PALMATA: vein protector, draining  SVELTONYL: inhibits phosphodiesterase, draining PRESENTATION  Retail: not available  Professional use: 500-ml bottle Ref. E883
  • 33. LIPO-MASSAGE ZEOLITHE THERMO-RELAXING ACTION INDICATION  Optimal body relaxation, helps the absorption of slimming ingredients due to the warm sensation produced upon application. DIRECTIONS FOR USE  Perform a relaxing massage to tense areas and knead areas with cellulite. INGREDIENTS  GREEN TEA: lipolytic  GUARANA: stimulates lipolysis  MATE: lipolytic  PASSIFLORA: vein protector PRESENTATION  Retail: not available  Professional use: 500-ml bottle – Ref. E884
  • 34. FLUIDE DESTRESS STRONG SKIN NEUROPROTECTOR INDICATION  Stimulates anti-stress receptors due to the release of β-endorphins. DIRECTIONS FOR USE  Mix DESTRESS FLUID with NEUROLYSIS SERUM in the DESTRESS bottle. Give it a lengthy shake. Apply morning and evening to cellulite areas. See professional protocol. INGREDIENTS  GLUTRAPEPTIDE: stimulates neurolipolysis  BETAPHROLINE: stimulates the release of β-endorphins -  WHITE TEA: lipolytic, anti-inflammatory, antioxidant  TAMANU OIL: vein protector  KIMARINE: antioxidant PRESENTATION  Retail: 150-ml bottle - Ref. E879 in box - Ref. E881  Professional use: 200-ml tube - Ref. E885
  • 35. NEUROLYSE SERUM STRONG SKIN NEUROPROTECTOR INDICATION  Smoothing effect on unsightly cellulite dimpling. DIRECTIONS FOR USE  Mix DESTRESS FLUID with NEUROLYSE SERUM in the DESTRESS bottle. Give it a lengthy shake. Apply morning and evening to cellulite areas. INGREDIENTS PALMARIA PALMATA: vein protector, draining  SVELTONYL: inhibits phosphodiesterase, draining PRESENTATION  Retail: 10-ml bottle - Ref. E880 in box Ref. E881  Professional use: not available
  • 36. SALON TREATMENT PROTOCOL INDICATION A new-generation slimming treatment   Dual action on neuromodulators, on the surface and deep down  Release of relaxing molecules. DANGER  WARNING!   DO  NOT  USE  THE  ELECTRIC  BLANKET  IN  THIS  TREATMENT   AT  THE  SAME  TIME  AS  THE  ALUMINIUM  FOIL  SHEET.   NB.  This  treatment  can  be  carried  out  without  a  shower.   PREPARING THE TREATMENT BED WITH AN ELECTRIC BLANKET WITHOUT AN ELECTRIC BLANKET Open out the blanket and cover it Open out the SLIM EXPRESS with a plastic sheet E07. ALUMINIUM FOIL E602 Lay a large towel Lay a large towel to prevent the (client comfort) skin from sticking to the sheet and reduce the rustle of the sheet Lay another plastic sheet E07 Lay a plastic sheet E07 folded in half for the scrub folded in half for the scrub
  • 37. SALON TREATMENT PROTOCOL EXFOLIATION FRONT / BACK Proceed with a complete scrub of the front of the body with LIPO-GUM E882. Make alternating movements until complete elimination of the product. Shower is not necessary. Proceed with a scrub on the back. Once the scrub is over, remove the plastic sheet. RELEASING TENSIONS BACK Using one AQ-PRESS E886 device in each hand, position them on the acupuncture points as shown in the diagrams here opposite and press firmly on the handles to make the devices vibrate. Each pressure should last at least 10 seconds. From the feet moving upwards to the shoulders.
  • 38. SALON TREATMENT PROTOCOL APPLYING E883 SOLUTION NEUROLYSE BACK Apply on the cellulite areas. THERMO-RELAXING MASSAGE BACK Carry out a long massage with ZEOLITE LIPO-MASSAGE E884 all over the body. During the massage, add a blob of product regularly to boost the thermo-heating effect. Apply a thick layer of ZEOLITE LIPO-MASSAGE E884. The client turns over. Repeat steps 2, 3 and 4 on the front side.
  • 39. SALON TREATMENT PROTOCOL BODY WRAP Cover the client with the SLIM EXPRESS E602 aluminium sheet or the PLASTIC SHEET E07 for 20min. Clean the skin with hot towels or a shower. Reminder: you can use an electric blanket instead of the aluminium sheet. Danger warning: Do not use the aluminium SLIM EXPRESS (E602) together with he electric blanket. In this case, replace with a plastic sheet (E07). END OF TREATMENT MASSAGE FRONT / BACK Apply DESTRESS FLUID E885 all over the body. LENGTH OF TREATMENT = 1HR 15MIN. 8-SESSION TREATMENT FREQUENCY = TWICE A WEEK
  • 40. LIPO-STRESS NEURO-LIPOLYSE STIMULATION LIPO-STRESS : A new-generation slimming treatment A DUAL ACTION ● In the upper skin layers: BETAPHROLINE ✓ Increases the production of β-endorphins → Relieves tensions → Helps the elimination of fat:  stimulation of Adenylyl cyclase by 85%. ● In the deeper skin layers: GLUTRAPEPTIDE ✓Improves innervation of adipose tissue → Relieves congestion of adipocytes LIPOLYSIS GENERATED BY NEURONS IS STIMULATED BY 51% LIPO-STRESS ACTIONS: ◆ Relieve painful localized cellulite ◆ Decrease stress in body prone to fat retention.