2. LIPO-STRESS
NEURO-LIPOLYSIS STIMULATION
STRESS = the bane of the
century
➥ It upsets:
✓ our behavior
✓ the body metabolism.
It causes skin reactions:
◆ Overreacting skin,
◆ Nerve blockage,
◆ High blood pressure,
◆ Poor elimination,
◆ General or localized fat
storage.
3. NEURO-COSMETICS
New scientific technology:
➥ demonstrates interactions between
the nervous system and the skin
through neurotransmitters.
Neurotransmitters:
◆ Regulate messages sent from the brain,
◆
Relay nerve impulse.
Neuro-cosmetics is the perfect partner for
neuro-aesthetics techniques, such as:
✓ Acupuncture
✓ Acupressure
➥ Increase of β-endorphins, pain-killer
molecules.
4. LIPO-STRESS
NEURO-LIPOLYSIS STIMULATION
A new generation slimming treatment.
A DUAL ACTION
● In skin upper layers
✓ Increases the production of β-endorphins
→ Releases tensions
→ Eases elimination of fat deposits
● In skin deeper layers
✓Improves the innervation of adipose tissue
→ Relieves congestion of adipocytes
LIPO-STRESS ACTIONS:
◆ Relieves painful localized cellulite
◆ Decreases stress in body prone to fat retention.
6. RELATIONSHIP BETWEEN SKIN STRESS AND CELLULITE
● Due to the release of neurotransmitters,
the skin nervous system controls:
✓ Cell proliferation and differentiation:
keratinocytes, adipocytes
✓ Production of neurotransmitters
✓ Activation of immune cells.
➡ BUT stress upsets the fragile balance
of the skin neuromodulators:
➪ Eases fat storage
➪ Limits fat release.
7. SOLUTION: ENDORPHINS TO FEND OFF STRESS
• Endorphins: specific neurotransmitters produced by
nerve endings and keratinocytes.
➔ ANTI-STRESS, pain-killer effect, feeling of well-being.
• Due to relaxation:
✓ Lipogenesis resulting from stress
decreases
✓ Lipolysis is triggered.
➠ Cellulite is reduced
➠ Orange peel skin is improved.
• You feel better about yourself
➔ the downward spiral generated by stress is
discontinued.
8. NEUROCOSMETICS: RELEASE OF β-ENDORPHINS
BETAPHROLINE: new patented neurocosmetic active
ingredient of plant origin.
• Tephrosia purpurea extract: plant
native to the tropical regions of
India, Africa and Sth America.
• BETAPHROLINE stimulates the
release of ß-endorphins by
keratinoyctes.
9. BETAPHROLINE IN VITRO TEST
STIMULATION OF THE RELEASE OF ß-ENDORPHINS
BY KERATINOCYTES
Test carried out on a culture of human keratinocytes
incubated for 24 hours.
+163%
Increase of
β-endorphins
➥ANTI-STRESS
ACTION
10. BETAPHROLINE: STIMULATION OF LIPOLYSIS
• Numerous enzymatic reactions occur
within adipocytes resulting in:
➔ either lipogenesis
➔ or lipolysis.
• In vitro tests demonstrate
the efficacy of
BETAPHROLINE:
➠ To stimulate lipolysis
➠ To reduce lipogenesis.
11. BETAPHROLINE: STIMULATION OF cAMP
• Lipolysis requires a particular messenger: cyclic AMP,
(cAMP) Adenosine Mono Phosphate derived from ATP.
cAMP is stimulated by an enzyme: adenylyl cyclase.
+ 85 %
Activation of
ADENYLYL CYCLASE
➥ Increase
in lipolysis
12. BETAPHROLINE: INHIBITION OF LIPOGENESIS
• Lipogenesis is activated in adipocytes by the enzyme
Glycerol-3-Phosphate Di-Hydrogenase or G3PDH
➠ Storage of carbs into triglycerides.
INHIBITION of G3PDH
due to BETAPHROLINE:
- 60 %
➥ Decrease in
Lipogenesis
➥ Activation
of lipolysis
13. AQ-PRESS RELIEVES TENSION POINTS AND
STIMULATES β-ENDORPHINS
• AQ-PRESS: ACUPRESSURE device using VIBRATIONS
➠ Release of ß-endorphins.
• AQ-PRESS provides:
✓ a thorough body relaxation
✓ a relief of tensions.
• Combined with the LIPO-STRESS
treatment protocol:
➠ EASES THE SLIMMING PROCESS.
14. AQ-PRESS RELIEVES TENSION POINTS AND
STIMULATES β-ENDORPHINS
• AQ-PRESS:
ACUPRESSURE of ACUPUNCTURE
points on the body:
➔ Restores energy flow
➔ Strengthens body metabolism
➔ Improves well-being.
16. NERVOUS SYSTEM: NEURON
A neuron has a cell body with profusely branching
extensions extruding from it.
✓ Dendrites →
receive and convey messages or nerve impulse
coming from other nerve cells, to the cell body of
the neuron.
✓ The axon → transmits
signals (nerve impulse)
to the other cells of the
body.
The transmission of nerve
impulse takes place through
different neurotransmitters.
17. THE DEEP CUTANEOUS NERVOUS SYSTEM
Skin nerves answer to stimuli coming from:
• Blood circulation
• Emotional stress.
Due to the production of chemical modulators, they
can process information within the skin regarding:
✓ Vasomotion,
✓ Thermoregulation,
✓ Secretion of glands
and cells such as
fibroblasts, adipocytes
✓ Tissue growth and
differentiation.
18. THE DEEP CUTANEOUS NERVOUS SYSTEM
• In the skin, neuromodulators such as endorphins are
produced by:
✓ Skin nerve fibers,
✓ Keratinocytes,
✓ Fibroblasts.
• Keratinocytes, fibroblasts
and adipocytes CAN
also synthesize:
→ growth factors.
19. SKIN GROWTH FACTORS
• Specific proteins that:
✓Participate in the
proliferation of different
cell types
✓Exert numerous functions
in the development of the
body.
• Rita Levi-Montalcini won the Nobel Prize in Medicine
in 1986 for the discovery of the Nerve Growth Factor,
NGF.
• NGF: the 1st growth factor that has been discovered.
• Since then, various growth factors have been
identified: the epidermal growth factor (EGF), the fibroblast
growth factor (FGF), etc.
20. NGF: NERVE GROWTH FACTOR
• NGF:
✓Facilitate the growth of nerve extensions
✓ Keep neuron alive
✓ Work on ADIPOCYTE functioning.
They are produced in limited quantities.
➤ COMPETITION BETWEEN NEURONS
➥ Neurons without NGF stimulation disappear by
apoptosis or process of programmed cell death.
21. GROWTH FACTOR AND CELLULITE
• Development of cellulite:
✓ Hypertrophy of adipocytes
✓ Disruption:
◆ of innervation
◆ of blood and lymph circulation.
• Cell aging
➥ Causes a decrease of NGF
synthesis.
➥ Hinders communication
between cells.
22. GROWTH FACTOR AND CELLULITE
NEW PATHWAY IN THE FIGHT AGAINST CELLULITE
Protecting neurons by
NGF helps:
◆ Stimulate lipolysis
◆ Reduce lipogenesis
◆ Prevent tissue hypoxia
and oxidative stress,
➤ which triggers fat
storage.
23. GROWTH FACTOR AND CELLULITE
Statement in laboratory:
• Optimum innervation of the adipose tissue,
• The more NGF,
⇒ the easier the lipolysis process.
24. GROWTH FACTOR AND CELLULITE
RESULTS:
⇒ The NGF is in direct contact with adipocytes: no effect on
lipolysis
⇒ Low innervation of the adipose tissue with the NGF
triggers a slight increase in lipolysis: + 32%
⇒ Optimal innervation of the adipose tissue with the NGF
triggers a significant increase in lipolysis: +117%
OPTIMUM INNERVATION RESULTS IN
OPTIMAL LIPOLYSIS
25. GLUTRAPEPTIDE: NEUROPROTECTION & NEUROLIPOLYSIS
Our research laboratories have developed a new active ingredient
for NEUROPROTECTION: GLUTRAPEPTIDE derived from biotechnology.
GLUTRAPEPTIDE: NGF-LIKE
➤ Activates innervation of adipose tissue
➤ Potentializes the neuron answer to the NGF
➤ Protects deep nerve endings
➤ Stimulates optimum lipolysis by acting on the length of
nerve fibers (neurite).
GLUTRAPEPTIDE helps reach optimal innervation characterized
by an average length of neurite of more than 20%
26. GLUTRAPEPTIDE: OPTIMIZATION OF LIPOLYSIS
Acting on neurons, GLUTRAPEPTIDE increases:
➤ Their survival rate
➤ Their metabolic activity
➤ Their ability to optimize lipolysis.
GLUTRAPEPTIDE increases
the release of glycerol by
51%
27. FIRMING EFFECT OF GLUTRAPEPTIDE
IN VIVO TEST:
GLUTRAPEPTIDE potentializes the action of the NGF on:
✓ Fibroblast contraction
✓ Collagen fibers
⇒ IMMEDIATE TIGHTENING EFFECT
⇒ LONG TERM EFFECT: FIRMER SKIN WITH MORE TONE
Increase in lipolysis:
- 4 cm in arm
- 6 cm in hip
- 3.5 cm in thigh
circumference
GLUTRAPEPTIDE improves skin firmness, elasticity and
density after only 28 days
31. LIPO-GUM
SLIMMING EXFOLIATION
INDICATION
Quickly eliminates dead cells. Activates microcirculation, provides better
tissue oxygenation, stimulates the release of β-endorphins.
DIRECTIONS FOR USE
Apply all over the body and carry out a message using circular
movements. Rinse with hot towels. See our professional protocol.
INGREDIENTS
GLUTRAPEPTIDE: stimulates neurolipolysis
BETAPHROLINE: stimulates the release of β-endorphins
ELEUTHERO: toning, rich in vitamins B
WAKAMINE: lightens the skin
PINEAPPLE: draining
GRAPEFRUIT: toning, anti-elastase
PRESENTATION
Retail: not available
Professional use: 400-ml pot - Ref. E882
32. SOLUTION NEUROLYSE
INDICATION
Strengthens skin neuroprotection, stimulates
neurolipolysis.
DIRECTIONS FOR USE
Apply on cellulite areas.
See professional protocol.
INGREDIENTS
GLUTRAPEPTIDE: stimulates neurolipolysis
BETAPHROLINE: stimulates the release of β-endorphins
PALMARIA PALMATA: vein protector, draining
SVELTONYL: inhibits phosphodiesterase, draining
PRESENTATION
Retail: not available
Professional use: 500-ml bottle Ref. E883
33. LIPO-MASSAGE ZEOLITHE
THERMO-RELAXING ACTION
INDICATION
Optimal body relaxation, helps the absorption of
slimming ingredients due to the warm sensation
produced upon application.
DIRECTIONS FOR USE
Perform a relaxing massage to tense areas and knead
areas with cellulite.
INGREDIENTS
GREEN TEA: lipolytic
GUARANA: stimulates lipolysis
MATE: lipolytic
PASSIFLORA: vein protector
PRESENTATION
Retail: not available
Professional use: 500-ml bottle – Ref. E884
34. FLUIDE DESTRESS
STRONG SKIN NEUROPROTECTOR
INDICATION
Stimulates anti-stress receptors due to the release of
β-endorphins.
DIRECTIONS FOR USE
Mix DESTRESS FLUID with NEUROLYSIS SERUM in the DESTRESS
bottle. Give it a lengthy shake. Apply morning and evening
to cellulite areas. See professional protocol.
INGREDIENTS
GLUTRAPEPTIDE: stimulates neurolipolysis
BETAPHROLINE: stimulates the release of β-endorphins
- WHITE TEA: lipolytic, anti-inflammatory, antioxidant
TAMANU OIL: vein protector
KIMARINE: antioxidant
PRESENTATION
Retail: 150-ml bottle - Ref. E879 in box - Ref. E881
Professional use: 200-ml tube - Ref. E885
35. NEUROLYSE SERUM
STRONG SKIN NEUROPROTECTOR
INDICATION
Smoothing effect on unsightly cellulite dimpling.
DIRECTIONS FOR USE
Mix DESTRESS FLUID with NEUROLYSE SERUM in the
DESTRESS bottle. Give it a lengthy shake. Apply
morning and evening to cellulite areas.
INGREDIENTS
PALMARIA PALMATA: vein protector, draining
SVELTONYL: inhibits phosphodiesterase, draining
PRESENTATION
Retail: 10-ml bottle - Ref. E880 in box Ref. E881
Professional use: not available
36. SALON TREATMENT PROTOCOL
INDICATION
A new-generation slimming treatment
Dual action on neuromodulators, on the surface and deep down
Release of relaxing molecules.
DANGER
WARNING!
DO
NOT
USE
THE
ELECTRIC
BLANKET
IN
THIS
TREATMENT
AT
THE
SAME
TIME
AS
THE
ALUMINIUM
FOIL
SHEET.
NB.
This
treatment
can
be
carried
out
without
a
shower.
PREPARING THE TREATMENT BED
WITH AN ELECTRIC BLANKET WITHOUT AN ELECTRIC BLANKET
Open out the blanket and cover it Open out the SLIM EXPRESS
with a plastic sheet E07. ALUMINIUM FOIL E602
Lay a large towel Lay a large towel to prevent the
(client comfort) skin from sticking to the sheet and
reduce the rustle of the sheet
Lay another plastic sheet E07 Lay a plastic sheet E07
folded in half for the scrub folded in half for the scrub
37. SALON TREATMENT PROTOCOL
EXFOLIATION
FRONT / BACK
Proceed with a complete scrub of the front of
the body with LIPO-GUM E882.
Make alternating movements until complete
elimination of the product. Shower is not necessary.
Proceed with a scrub on the back.
Once the scrub is over, remove the plastic sheet.
RELEASING TENSIONS
BACK
Using one AQ-PRESS E886
device in each hand,
position them on the
acupuncture points as shown in the diagrams here opposite
and press firmly on the handles to make the devices vibrate.
Each pressure should last at least 10 seconds.
From the feet moving upwards to the shoulders.
38. SALON TREATMENT PROTOCOL
APPLYING E883 SOLUTION NEUROLYSE
BACK
Apply on the cellulite areas.
THERMO-RELAXING MASSAGE
BACK
Carry out a long massage with
ZEOLITE LIPO-MASSAGE E884 all over the body.
During the massage, add a blob of product regularly
to boost the thermo-heating effect.
Apply a thick layer of ZEOLITE LIPO-MASSAGE E884.
The client turns over. Repeat steps 2, 3 and 4 on the front side.
39. SALON TREATMENT PROTOCOL
BODY WRAP
Cover the client with the SLIM EXPRESS E602
aluminium sheet or the PLASTIC SHEET E07 for 20min.
Clean the skin with hot towels or a shower.
Reminder: you can use an electric blanket instead of the aluminium sheet.
Danger warning: Do not use the aluminium SLIM EXPRESS (E602) together with he
electric blanket.
In this case, replace with a plastic sheet (E07).
END OF TREATMENT MASSAGE
FRONT / BACK
Apply DESTRESS FLUID E885 all over the body.
LENGTH OF TREATMENT = 1HR 15MIN.
8-SESSION TREATMENT
FREQUENCY = TWICE A WEEK
40. LIPO-STRESS
NEURO-LIPOLYSE STIMULATION
LIPO-STRESS : A new-generation slimming treatment
A DUAL ACTION
● In the upper skin layers: BETAPHROLINE
✓ Increases the production of β-endorphins
→ Relieves tensions
→ Helps the elimination of fat:
stimulation of
Adenylyl cyclase by 85%.
● In the deeper skin layers: GLUTRAPEPTIDE
✓Improves innervation of adipose tissue
→ Relieves congestion of adipocytes
LIPOLYSIS GENERATED BY NEURONS IS STIMULATED BY 51%
LIPO-STRESS ACTIONS:
◆ Relieve painful localized cellulite
◆ Decrease stress in body prone to fat retention.