2. • What is osteomyelitis?
• Predisposing factors of osteomyelitis?
• Classification
Clinical features
Radiographic features
• Management of osteomyelitis
• What is Alveolar osteitis?
• Pathogenesis
Clinical features
• Treatment
3. • Osteon: Bone
• Myelitis: Inflammation of the bone marrow
• Acute or chronic inflammatory process in the
medullary spaces or cortical surfaces of the bone
that extends away from the initial site of
involvement
4. Decreased vascularity
or Vitality of bone
• Trauma
• Radiation injury
• Paget’s disease
• Osteoporosis
• Major vessel disease
Impaired host defence
• Immune deficiency state
• Immunosuppression
• Diabetes Mellitus
• Malnutrition
• Extremes of age
Local factors Systemic factors
8. Organism enters the jaw (mandible) blood supply
Medullary infection spreads through marrow spaces
Thrombosis, bone necrosis
Lacunae empty of osteoid filled with neutrophil & bacteria
proliferate in dead tissue
Proliferation of periosteum & sinus formation
Sequestrum separated once removed, new bone is
formed (INVOLUCRUM)
11. • It may be normal in the early stages of the disease, but
after 10-14 days sufficient bone resorption may have
occurred to produce irregular, MOTH-EATEN areas of
radiolucency.
15. C/F
• Age: Children and young adults
• Location: Mandibular premolar and molar
• Bone sclerozing associated with non vital
pulpitic tooth
16. • Increased areas of radiodensity surround the apices
of non-vital mandibular 1st molar
17. C/F
• Age: Adults
• No sex predilection
• Location: Mandible
• Sclerosing around the site of periapical/PD inflammation
• Persistent pain
• No swelling
19. C/F
• Age: Children and young adults.
• Location: Lower border of the mandible.
• No sex predominance.
20. • New periosteal bone formation along the inferior border of
the mandible
• CT image: new periosteal bone growth with onionskin
lamination
21. Essential measures:
Bacterial sampling and
culture
Vigorous (empirical)
antibiotic treatment
Drainage
Analgesic
Specific antibiotics
Debridement
Adjunctive treatment:
Sequestrectomy
Decortication
Resection and
reconstruction for
extensive bone
destruction
Hyperbaric oxygen
For acute osteomyelitis antibiotic treatment for 4-6
wks
For chronic osteomyelitis treatment is carried for
12 wks
22.
23. • Localized inflammation of the bone following:
Failure of blood clot to form in the socket
Premature loss of the clot
Disintegration of the clot
• Common complication following
tooth extraction
24. Food debris Bacteria Saliva
Empty socket
Bone becomes
infected &
necrotic
Inflammatory
reactions in the
adjacent marrow
Localizes it to
the socket wall
Osteomyelitis
Necrotic bone is
separated by
osteoclast
Tiny
sequestra
Proliferation of
granulation tissue from
surrounding vital bone
HEALING
25. • Location: Mandible in posterior areas.
• No sex predilection
• Severe pain
• Radiates to ear and neck
• Foul odor
• Lymphadenopathy
• Trismus
26.
27. • Administration of regional local anesthesia
• Debridement of socket wall
• Irrigate with normal saline
• Antiseptic/analgesic
Alvogel
Zinc oxide/eugenol pack
Chlorhexidine gel
Tetracycline pack
NO drainage.
28. • Chlorhexidine mouth rinses should be done gently.
• Patient should not smoke minimum for 48 hours after
extraction.
• Patient should avoid sucking, spitting or drinking through
the straw.
• Patient should try to maintain good oral hygiene
29. • CAWSON
• J.V. SOAMES & J.C. SOUTHAM
• NEVILLE & DAMM
• GOOGLE for images
Notes de l'éditeur
(a) CT scan (bone windowing) demonstrates a nonexpansile, osteolytic lesion (arrow) within the right mandible. Perimandibular soft-tissue inflammatory change (arrowheads) is also present.
Chronic suppurative osteomyelitis with three sequestra (arrows). Osteolytic as well as sclerotic areas are present.
CT scan reveals an osteolytic lesion (arrow) containing a bony sequestrum (arrowhead) within the left mandibular body.
It is suggested that trauma and infection causes inflammation of the bone marrow which causes release of tissue activators. Plasminogen which is present in the clot is converted into plasmin by the action of tissue activators. Plasmin is a fibrinolytic agent and will dissolve the blood clot. It will also release kinins which will cause severe pain to the patient.