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We have indeed created man in the best shape (Holy Quran) Lecture # 2 Biochemistry Foundation Module November-2010
Growth and reproduction and all other vital process depend on Hundreds of planned chemical reactions called metabolic reactions
Energy is fundamental requirement of living systems   ,[object Object],[object Object],[object Object],[object Object],[object Object]
In living system energy is generated by precise chemical methods ,[object Object],[object Object],[object Object],[object Object]
Bioenergetics (Biochemical thermodynamics) ,[object Object],[object Object]
Sources of Energy In Human cells ,[object Object],[object Object],[object Object],[object Object],[object Object]
Storage of energy in living system ,[object Object],[object Object],[object Object]
Adenosine Triphosphate (ATP) is the most commonly used Energy Storing Molecule Adenine | Ribose_______P Adenosine Monophosphate ~  P  ~  P High Energy  Phosphate Bonds
Capture of Energy as ATP Adenine | Ribose_______P ~ P   ~ P Energy generated by oxidation of food stuffs is utilized for the formation of High- energy phosphate bonds. ADP is converted to ATP
Release of energy by ATP Adenine | Ribose_______P ~ P ~ P Hydrolysis of terminal    Generates 7300 Calories. ATP is Converted to ADP
Release of energy by ATP ,[object Object],[object Object],[object Object]
Release of energy by ATP Adenine | Ribose_______P  ~ P  +  Pi Energy generated is utilized for: 1. Metabolic Reactions. 2. Muscle Contraction. 3. Heat.
An Overview of Energy Storage Adenine | Ribose__P Adenosine Monophosphate Adenine | Ribose__P __P Adenosine Diphosphate Adenine | Ribose__P __P __P Adenosine Triphosphate Catabolism of Nutrients CO2 + H2O Energy
ATP / ADP Cycle Adenine | Ribose — P ~    ~     ATP Adenine | Ribose — P ~     ADP 7300 cal/mol
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Organic molecules  (Nutrients Such as Glucose & Fats)  contain energy, stored in their molecular structure ,[object Object]
Generation and utilization of energy in human tissues is an important concern in medical science  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cellular Respiration is the Main Source of Energy ,[object Object],[object Object]
Cellular respiration is a complex biochemical phenomena backed up by: ,[object Object],[object Object],[object Object],[object Object],[object Object]
To generate energy through Cellular respiration a cell must have:  ,[object Object],[object Object],[object Object],[object Object]
Role of Carbohydrates, Fats, and Proteins Cellular Respiration Carbohydrates Proteins Fats Glucose Amino acids Fatty acids Glycerol CO2  +  H2O  +  ATP (Energy)
Breakdown (Catabolism) of molecules generate the energy to synthesize ATP ,[object Object],[object Object],[object Object],[object Object]
Metabolic Processes Involved In Cell Respiration ,[object Object],[object Object],[object Object]
Two types of Cellular Respiration  ,[object Object],[object Object]
Aerobic Respiration ,[object Object],[object Object],[object Object],[object Object]
Anaerobic Respiration ,[object Object],[object Object],[object Object]
A number of NAD and FAD molecules are reduced by H +  generated during Glycolysis, Oxidation of Fatty acids and Krebs Citric acid Cycle  ,[object Object]
Biological oxidation in the mitochondria is the final and most important step of cellular respiration ,[object Object],[object Object]
Cellular Respiration Glycolysis, Oxidation of Fatty acids and catabolism of Amino acids Citric Acid Cycle NADH FADH2 Biological Oxidation ADP ATP
The Final Stage of Cellular Respiration called Biological Oxidation ,[object Object]
Biological Oxidation ,[object Object],[object Object],[object Object],[object Object],1. 2.

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11.13 (dr. saleem) overview of metabolism & bioenergetics ii oidative phosphorylation & electron transport chain

  • 1. We have indeed created man in the best shape (Holy Quran) Lecture # 2 Biochemistry Foundation Module November-2010
  • 2. Growth and reproduction and all other vital process depend on Hundreds of planned chemical reactions called metabolic reactions
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  • 8. Adenosine Triphosphate (ATP) is the most commonly used Energy Storing Molecule Adenine | Ribose_______P Adenosine Monophosphate ~ P ~ P High Energy Phosphate Bonds
  • 9. Capture of Energy as ATP Adenine | Ribose_______P ~ P ~ P Energy generated by oxidation of food stuffs is utilized for the formation of High- energy phosphate bonds. ADP is converted to ATP
  • 10. Release of energy by ATP Adenine | Ribose_______P ~ P ~ P Hydrolysis of terminal  Generates 7300 Calories. ATP is Converted to ADP
  • 11.
  • 12. Release of energy by ATP Adenine | Ribose_______P ~ P + Pi Energy generated is utilized for: 1. Metabolic Reactions. 2. Muscle Contraction. 3. Heat.
  • 13. An Overview of Energy Storage Adenine | Ribose__P Adenosine Monophosphate Adenine | Ribose__P __P Adenosine Diphosphate Adenine | Ribose__P __P __P Adenosine Triphosphate Catabolism of Nutrients CO2 + H2O Energy
  • 14. ATP / ADP Cycle Adenine | Ribose — P ~  ~  ATP Adenine | Ribose — P ~  ADP 7300 cal/mol
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  • 21. Role of Carbohydrates, Fats, and Proteins Cellular Respiration Carbohydrates Proteins Fats Glucose Amino acids Fatty acids Glycerol CO2 + H2O + ATP (Energy)
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  • 29. Cellular Respiration Glycolysis, Oxidation of Fatty acids and catabolism of Amino acids Citric Acid Cycle NADH FADH2 Biological Oxidation ADP ATP
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  • 31.