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Prevention of tooth loss
and dental pain for
reducing the global
burden of oral diseases
FDI World Dental Congress
Oral Health for an Ageing Population
Poznan, Poland September 7-10, 2016
Susan Hyde, DDS, MPH, PhD
Sophie Dartevelle, DDS
Veronique Dupuis, DDS, PhD
Boipelo P. Mariri, DDS, MS
September 10, 2016
Outline
• Life course approach
• Global burden of oral diseases
– Community-dwelling
– Homebound and long-term care residents
• Disease models, risk assessment
• Effectiveness, cost analysis, and
recommendations for preventive interventions
– Seattle Care Pathway
– Alternative models of care
– Interprofessional opportunities
• Oral health policy
2
Thomson et al.
Community Dent
Oral Epidemiol.
2004
Centers for
Disease Control
and Prevention.
USDHHS 2013.
Life-course Approach to Oral Health
• Caries and periodontal disease are chronic
conditions, highly prevalent, largely irreversible,
and cumulative in nature
– Social inequities follow the life course
– Unconscious bias affects oral health and treatment
• Older adults present with wide-ranging clinical
needs and levels of wellbeing
– Two-thirds of older Americans have multiple chronic
diseases
– Functional limitation decreases the ability for self-
care
– Polarized delivery of dental care during the last year
of life
Chen et al. J Am
Dent Assoc 2013.
Global Burden Untreated Caries = 35%
4Image = http://www.map-menu.com/
47%
20%
21%19% coronal
14% root
Age-standardizedKassebaum et al.
J Dent Res 2015.
Global Burden Severe Periodontitis = 11%
5Image = http://www.map-menu.com/
10%
51%
19%
Aged 65+ yearsKassebaum et al.
J Dent Res 2014.
Global Burden Severe Tooth Loss = 2.3%
6Image = http://www.map-menu.com/
Aged 65+ years
30%
9%
19%
Average
19 teeth
Kassebaum et al.
J Dent Res 2014.
Global Burden Oral Diseases
7Image = http://www.map-menu.com/
Oral Conditions Combined = 15 million DALYs
Average Health Loss = 224 years/100,000 population
Economic Burden = $USD442 billion
Marcenes 2013.
Listl 2015.
Frail Older Adults
• Oral disease estimates of homebound adults
– Poor oral health (79% caries), high unmet need (34%
pain) and preference for in-home dental services (94%)
• Oral disease estimates in long-term care
– 59% of dentate have untreated caries (34% major-
urgent treatment needs), 74% gingivitis
– 50% of edentulous don’t have dentures
• Assessment, daily oral care, and referral
– Assessment = 78% performed by nurses
– Daily oral hygiene = 25% missing products, 16%
received assistance
– Barriers to care = shortage of dental professionals,
complexity of patient and environment, cost of dental
care, insurance status, and low reimbursement
8
MA Dept Pub
Health Office of
Oral Health 2010.
Dharamsi et al. J
Dent Educ 2009.
Coleman and
Watson. J Am
Geriatr Soc 2006.
Ornstein et al. J
Am Geriatr Soc
2015.
Multifactorial Model Dental Caries
9Image = http://www.nap.edu/read/13086/chapter/4
Fisher-Owens et
al. Pediatrics
2007.
Caries Risk
Assessment
Featherstone et al.
J Calif Dent Assoc
2007.
Root Caries
Aged 65+
1100ppm F
Toothpaste
F-Triclosan
Toothpaste
F-ACP
Toothpaste
5000ppm F
Toothpaste
225-900ppm
F Rinse
NaF Varnish Chlorhexi-
dineVarnish
Silver
Diamine F
Prevention 67% 90% 98% MD = -0.18
36%
56-64% MD = -0.67
41-57%
MD = -0.33
72%
Arrest RR = 0.49
52-82%
54-92% MD = -0.24
90%
Cost/Year $36 $48 $72 $365 $64 $7 $12 $1
ACP = amorphous calcium phosphate
Bold = meta-analysis; otherwise randomized clinical trial
MD = mean difference; RR = relative risk
Li 2016, Wierichs 2015, Gluzman 2013, Zhang 2013, Tan 2010.
Root Caries Prevention
Recommendations
• Community-dwelling older adults: triclosan-
fluoride or amorphous calcium phosphate-
fluoride toothpaste
• Frail older adults: 5000ppm fluoride toothpaste
and quarterly-application of
chlorhexidine/fluoride varnish or yearly silver
diamine fluoride is effective to decrease
progression and initiation of root caries
12
Gluzman et al.
Spec Care Dent
2013.
Wierichs et al. J
Dent Res 2015.
Gluzman et al.
Spec Care Dent
2013.
Multifactorial Model Periodontitis
13
Image = https://static-content.springer.com/image/art%3A10.1186%2F1472-6831-15-
S1-S6/MediaObjects/12903_2015_Article_521_Fig2_HTML.jpg
Mariotti and Hefti.
BMC Oral Health
2015.
14Image = https://perioprosthocc.wordpress.com/2015/10/16/periodontal-risk-assessment-pra-in-clinical-case-reviews-and-results/
Periodontal Risk
Assessment
Lang, Tonetti.
Oral Health Prev
Dent 2003.
15
Prophylaxis q3
vs 12 Months
Powered
Toothbrush
Add Interdental
Brushing/Floss
Triclosan
Toothpaste
Chlorhexidine
Rinse
Essential Oils
Rinse
(Listerine)
Plaque Index MD = -0.15 MD = -0.47
(21%)
MD = -0.95
(32%)
MD = -0.47
(22%)
MD = -0.68
(33%)
MD = -0.39
Gingivitis
Index
MD = -0.21 MD = -0.21
(11%)
MD = -0.53
(34%)
MD = -0.27
(22%)
MD = -0.24
(26%)
MD = -0.36
Bleeding
Index
MD = -0.13
(48%)
MD = -0.21
Attachment
Loss Not significant
Tooth Loss
Not significant
Cost/Year $320 $50 $32 $48 $342 $58
Bold = meta-analysis; otherwise randomized clinical trial
MD = mean difference
Periodontitis Prevention:
Effectiveness and Cost Analysis
Van Leeuwen 2014, Yaacob 2014, Poklepovic 2013, Riley 2013, Worthington 2013,
Van Strydonck 2012, Wyatt 2007.
Periodontitis Prevention
Recommendations
• Daily oral hygiene more effective for removing
plaque and preventing gingivitis than periodic
prophylaxis
– Powered toothbrushes, interdental brushes or floss,
triclosan toothpaste, chlorhexidine, and Listerine
provide adjunctive plaque control
– Repeated and tailored oral hygiene instruction is key
• Interventions which reduce plaque and
gingivitis do not translate into preventing
periodontitis or tooth loss
16
Matthews 2014.
Van Leeuwen 2014,
Yaacob 2014,
Poklepovic 2013,
Riley 2013, Van
Strydonck 2012.
Tonetti 2015.
Riley 2013,
Wayatt 2007.
No Dependency Pre Dependency Low Dependency Medium
Dependency
High Dependency
Description Fit, exercises
regularly
Well-controlled
chronic disease
Chronic disease
affects oral
health,
independent
Chronic disease,
ADL dependency,
home-bound
Complex medical
management,
long-term care
Assessment Oral health risk
assessments
Salivary flow Cause of
increasing
dependency
Polypharmacy,
ability to tolerate
treatment
Medical,
pharmacy, diet
assessments
Prevention 1100ppm F paste Powered brush, F
rinse
5000ppm F
paste, F varnish
Recall q3 months,
chlorhexidine
Silver diamine
fluoride
Treatment Full range of
treatment options
Plan easy
maintenance
treatment with
long-term viability
Repair/replace
strategic teeth to
maintain
shortened arch
Maintain
shortened dental
arch, F-releasing
restorations, ART
Palliative care
Communication Oral hygiene
instructions
Oral:systemic
health
connections
↑ dependency =
↑ oral health risk
Health care team,
caregivers
Director of
Nursing, family,
caregivers
.
Pretty et al.
Gerodontology 2014
18
Alternative Models of Care
Small Private Group Practice Large Corporate/Non-Profit
Solo Cooperative Collaborative Interprofessional
Business Model
Practitioner Organization
Mertz, Wides.
Oral Health
Workforce
Research Center
2015.
Interprofessional Opportunities
• Prevention
– Common risk factor approach
• Collaborative care model
– Diabetes toolkit for pharmacy, podiatry, optometry,
and dentistry
• Long-term care
– Increased presence of dental providers
– Training care providers in assessment and daily oral
care
MA Dept Pub
Health Office of
Oral Health 2010.
http://www.cdc.go
v/diabetes/ndep/to
olkits/ppod.html
Image = https://interprofessional.ucsf.edu
Watt. Community
Dent Oral
Epidemiol 2007.
Oral Health Policy Approaches
Watt. Community Dent Oral Epidemiol
2007.
Summary
• Untreated caries, periodontitis, and tooth loss
are prevalent among older adults
– Caries prevention treatments shown to reduce new
lesions
– Periodontitis prevention treatments not shown to
reduce attachment loss or tooth loss
• Assessment, prevention, treatment, and
communication must be provided appropriate to
the level of dependency
– Chronic disease prevention and management can
benefit from interprofessional collaboration
• Evidence-based practice needs to inform oral
health policy
21

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Prevention of tooth loss and dental pain for reducing the global burden of oral disease (Susan Hyde)

  • 1. Prevention of tooth loss and dental pain for reducing the global burden of oral diseases FDI World Dental Congress Oral Health for an Ageing Population Poznan, Poland September 7-10, 2016 Susan Hyde, DDS, MPH, PhD Sophie Dartevelle, DDS Veronique Dupuis, DDS, PhD Boipelo P. Mariri, DDS, MS September 10, 2016
  • 2. Outline • Life course approach • Global burden of oral diseases – Community-dwelling – Homebound and long-term care residents • Disease models, risk assessment • Effectiveness, cost analysis, and recommendations for preventive interventions – Seattle Care Pathway – Alternative models of care – Interprofessional opportunities • Oral health policy 2
  • 3. Thomson et al. Community Dent Oral Epidemiol. 2004 Centers for Disease Control and Prevention. USDHHS 2013. Life-course Approach to Oral Health • Caries and periodontal disease are chronic conditions, highly prevalent, largely irreversible, and cumulative in nature – Social inequities follow the life course – Unconscious bias affects oral health and treatment • Older adults present with wide-ranging clinical needs and levels of wellbeing – Two-thirds of older Americans have multiple chronic diseases – Functional limitation decreases the ability for self- care – Polarized delivery of dental care during the last year of life Chen et al. J Am Dent Assoc 2013.
  • 4. Global Burden Untreated Caries = 35% 4Image = http://www.map-menu.com/ 47% 20% 21%19% coronal 14% root Age-standardizedKassebaum et al. J Dent Res 2015.
  • 5. Global Burden Severe Periodontitis = 11% 5Image = http://www.map-menu.com/ 10% 51% 19% Aged 65+ yearsKassebaum et al. J Dent Res 2014.
  • 6. Global Burden Severe Tooth Loss = 2.3% 6Image = http://www.map-menu.com/ Aged 65+ years 30% 9% 19% Average 19 teeth Kassebaum et al. J Dent Res 2014.
  • 7. Global Burden Oral Diseases 7Image = http://www.map-menu.com/ Oral Conditions Combined = 15 million DALYs Average Health Loss = 224 years/100,000 population Economic Burden = $USD442 billion Marcenes 2013. Listl 2015.
  • 8. Frail Older Adults • Oral disease estimates of homebound adults – Poor oral health (79% caries), high unmet need (34% pain) and preference for in-home dental services (94%) • Oral disease estimates in long-term care – 59% of dentate have untreated caries (34% major- urgent treatment needs), 74% gingivitis – 50% of edentulous don’t have dentures • Assessment, daily oral care, and referral – Assessment = 78% performed by nurses – Daily oral hygiene = 25% missing products, 16% received assistance – Barriers to care = shortage of dental professionals, complexity of patient and environment, cost of dental care, insurance status, and low reimbursement 8 MA Dept Pub Health Office of Oral Health 2010. Dharamsi et al. J Dent Educ 2009. Coleman and Watson. J Am Geriatr Soc 2006. Ornstein et al. J Am Geriatr Soc 2015.
  • 9. Multifactorial Model Dental Caries 9Image = http://www.nap.edu/read/13086/chapter/4 Fisher-Owens et al. Pediatrics 2007.
  • 10. Caries Risk Assessment Featherstone et al. J Calif Dent Assoc 2007.
  • 11. Root Caries Aged 65+ 1100ppm F Toothpaste F-Triclosan Toothpaste F-ACP Toothpaste 5000ppm F Toothpaste 225-900ppm F Rinse NaF Varnish Chlorhexi- dineVarnish Silver Diamine F Prevention 67% 90% 98% MD = -0.18 36% 56-64% MD = -0.67 41-57% MD = -0.33 72% Arrest RR = 0.49 52-82% 54-92% MD = -0.24 90% Cost/Year $36 $48 $72 $365 $64 $7 $12 $1 ACP = amorphous calcium phosphate Bold = meta-analysis; otherwise randomized clinical trial MD = mean difference; RR = relative risk Li 2016, Wierichs 2015, Gluzman 2013, Zhang 2013, Tan 2010.
  • 12. Root Caries Prevention Recommendations • Community-dwelling older adults: triclosan- fluoride or amorphous calcium phosphate- fluoride toothpaste • Frail older adults: 5000ppm fluoride toothpaste and quarterly-application of chlorhexidine/fluoride varnish or yearly silver diamine fluoride is effective to decrease progression and initiation of root caries 12 Gluzman et al. Spec Care Dent 2013. Wierichs et al. J Dent Res 2015. Gluzman et al. Spec Care Dent 2013.
  • 13. Multifactorial Model Periodontitis 13 Image = https://static-content.springer.com/image/art%3A10.1186%2F1472-6831-15- S1-S6/MediaObjects/12903_2015_Article_521_Fig2_HTML.jpg Mariotti and Hefti. BMC Oral Health 2015.
  • 15. 15 Prophylaxis q3 vs 12 Months Powered Toothbrush Add Interdental Brushing/Floss Triclosan Toothpaste Chlorhexidine Rinse Essential Oils Rinse (Listerine) Plaque Index MD = -0.15 MD = -0.47 (21%) MD = -0.95 (32%) MD = -0.47 (22%) MD = -0.68 (33%) MD = -0.39 Gingivitis Index MD = -0.21 MD = -0.21 (11%) MD = -0.53 (34%) MD = -0.27 (22%) MD = -0.24 (26%) MD = -0.36 Bleeding Index MD = -0.13 (48%) MD = -0.21 Attachment Loss Not significant Tooth Loss Not significant Cost/Year $320 $50 $32 $48 $342 $58 Bold = meta-analysis; otherwise randomized clinical trial MD = mean difference Periodontitis Prevention: Effectiveness and Cost Analysis Van Leeuwen 2014, Yaacob 2014, Poklepovic 2013, Riley 2013, Worthington 2013, Van Strydonck 2012, Wyatt 2007.
  • 16. Periodontitis Prevention Recommendations • Daily oral hygiene more effective for removing plaque and preventing gingivitis than periodic prophylaxis – Powered toothbrushes, interdental brushes or floss, triclosan toothpaste, chlorhexidine, and Listerine provide adjunctive plaque control – Repeated and tailored oral hygiene instruction is key • Interventions which reduce plaque and gingivitis do not translate into preventing periodontitis or tooth loss 16 Matthews 2014. Van Leeuwen 2014, Yaacob 2014, Poklepovic 2013, Riley 2013, Van Strydonck 2012. Tonetti 2015. Riley 2013, Wayatt 2007.
  • 17. No Dependency Pre Dependency Low Dependency Medium Dependency High Dependency Description Fit, exercises regularly Well-controlled chronic disease Chronic disease affects oral health, independent Chronic disease, ADL dependency, home-bound Complex medical management, long-term care Assessment Oral health risk assessments Salivary flow Cause of increasing dependency Polypharmacy, ability to tolerate treatment Medical, pharmacy, diet assessments Prevention 1100ppm F paste Powered brush, F rinse 5000ppm F paste, F varnish Recall q3 months, chlorhexidine Silver diamine fluoride Treatment Full range of treatment options Plan easy maintenance treatment with long-term viability Repair/replace strategic teeth to maintain shortened arch Maintain shortened dental arch, F-releasing restorations, ART Palliative care Communication Oral hygiene instructions Oral:systemic health connections ↑ dependency = ↑ oral health risk Health care team, caregivers Director of Nursing, family, caregivers . Pretty et al. Gerodontology 2014
  • 18. 18 Alternative Models of Care Small Private Group Practice Large Corporate/Non-Profit Solo Cooperative Collaborative Interprofessional Business Model Practitioner Organization Mertz, Wides. Oral Health Workforce Research Center 2015.
  • 19. Interprofessional Opportunities • Prevention – Common risk factor approach • Collaborative care model – Diabetes toolkit for pharmacy, podiatry, optometry, and dentistry • Long-term care – Increased presence of dental providers – Training care providers in assessment and daily oral care MA Dept Pub Health Office of Oral Health 2010. http://www.cdc.go v/diabetes/ndep/to olkits/ppod.html Image = https://interprofessional.ucsf.edu Watt. Community Dent Oral Epidemiol 2007.
  • 20. Oral Health Policy Approaches Watt. Community Dent Oral Epidemiol 2007.
  • 21. Summary • Untreated caries, periodontitis, and tooth loss are prevalent among older adults – Caries prevention treatments shown to reduce new lesions – Periodontitis prevention treatments not shown to reduce attachment loss or tooth loss • Assessment, prevention, treatment, and communication must be provided appropriate to the level of dependency – Chronic disease prevention and management can benefit from interprofessional collaboration • Evidence-based practice needs to inform oral health policy 21

Notes de l'éditeur

  1. 25-30 minutes, 2-1/2 hours total, 5 speakers, 25 min discussion