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Credit Suisse First Boston
Global Healthcare Conference
      November 17, 2004
John H. Hammergren,
                Chairman and
            Chief Executive Officer




12/3/2004                     1
Safe Harbor Clause
   Some of the information in this presentation may
   constitute forward-looking statements that are
   subject to various uncertainties. These
   uncertainties could cause actual results to differ
   materially from those projected or implied. The risk
   factors associated with those uncertainties are
   described in the Company’s reports and exhibits
   filed with the Securities and Exchange
   Commission. Financial information is presented
   here in summary form. Full details are provided in
   the Company’s most recent 10-Q report. All of this
   information is available at www.mckesson.com.
12/3/2004                               2
Overview


     Who We Are


     Our View of Healthcare


     How Our Businesses Are Currently
     Performing




12/3/2004                        3
Who We Are




12/3/2004                4
McKesson’s Solutions …
  Building on Distribution Strength


                                          Solutions for
                                        medication safety
  Pharmaceutical & medical-
surgical distribution to all sites
                                                                           Clinical, financial &
                                                                         resource management
                                                                          for hospitals & IDNs




                          Inpatient automation
                                                          Specialty
Retail pharmacy                                        pharmaceuticals
  automation

                                                                                 Disease
                                                                               management
                       Drug cards for
                          seniors
                                                 Pharmaceutical
   12/3/2004                                                      5
                                                  repackaging
Our Business Today



                                                             McKesson
                                  McKesson
              McKesson
                                                        Provider Technologies
                                Medical-
                                Medical-Surgical
            Pharmaceutical
                                                        63% of health systems
                               #1 in primary care
    #1 in U.S., Canada, and
             Mexico
                                                        51% of hospitals with
                                #1 in extended
                                                            200+ beds
                                      care
      Large Rx repackaging
                                                         Leader in clinical,
                                  Total supply
   Leading generics provider
                                                           revenue cycle,
                                solution in acute
      #1 in retail pharmacy                                 and resource
                                       care
           automation                                   management solutions
                                 Private label
    Specialty distribution &                             More “Best in KLAS”
                               product offerings
      patient services for                                products than any
                                Rapid growth in
        manufacturers                                       other vendor
                                physician office
 #1 in medical management                                #1 in robotic hospital
                                pharmaceuticals
  software and services for                              pharmacy dispensing
                                 and equipment
           payors
                                                        #1 in bedside scanning
 #1 in disease management
    for Medicaid agencies
12/3/2004                                           6
Strong, Long-term Customer
Relationships with Market Leaders
             Vanderbilt University Medical Center




 12/3/2004                                     7
FY05 Consolidated Financial
               Results
($ and shares in millions,
                                          Q2                                 Six Months
except EPS)
                                 FY04              FY05                    FY04      FY05


Revenues                     $ 16,810          $ 19,934     19%        $ 33,334     $ 39,121   17%

Gross Profit                        812               735     -9%           1,598       1,587 -1%
 Gross Profit Margin              4.83%             3.69%   (114) bp        4.79%       4.06% (73) bp

Operating Income                    227               129   -43%              479         390 -19%
 Operating Income Margin          1.35%             0.65%    (70) bp        1.44%       1.00% (44) bp

Net Income                         157                86    -45%             312         250 -20%

Diluted EPS                  $     0.53        $     0.29   -45%       $     1.05   $   0.84 -20%

Weighted Average Shares            300               300                     299         300


 12/3/2004                                                             8
Our View of Healthcare




12/3/2004                    9
Trends Driving Healthcare
                   Growth
                   Reduce medical errors                                Payors taking on more risk
                   Adopt clinical protocols/                            Limitations on use of
                                                  Increased
                   evidence-based medicine                              managed care tools
  Focus on
                                                 pressure on            Employer pressures on
quality of care                                     payors              double-digit premium
                                                                        increases



                   Chronic disease                                      Automation to overcome
                                                    Continued
                   management                                           labor shortages
                                                improvements in
 Outpatient and    Case management                                      Electronic claims and
chronic disease                                  operational and
                   Manage high-cost diseases                            eligibility
  management                                      administrative
                   in small populations                                 Online prescription and lab
                                                    efficiency          transmissions
                                                                        Streamlined pre-authorization


                   Biotech pipeline expansion                           Unhappy consumers
                   New drug delivery                                    Better informed consumers
Continued use      mechanisms
 of new drugs,                                    Increased
                   Rapid growth in generics
 but increased                                   consumerism
                   Regulatory pressures on
pricing scrutiny
                   pricing



  12/3/2004                                                        10
Improved U.S. Healthcare
                    by 2010
            Informed clinical
             Informed clinical
                 practice
                  practice

                                      CULTURE
                                      CULTURE
            Interconnection
             Interconnection
                                       CHANGE
                                       CHANGE

            Improved safety
            Improved safety             in the
                                        in the
             and efficiency
             and efficiency
                                      delivery of
                                      delivery of

            Personalized care         healthcare
                                      healthcare
            Personalized care


            Population health
            Population health
               initiatives
                initiatives
12/3/2004                        11
McKesson’s Strategy
 To bring together clinical knowledge, process
   expertise, technology, and the resources of
     a Fortune 16 company to fundamentally
        change the cost and quality of healthcare.

 Create long-term                                Introduce
relationships based    Sell McKesson’s        innovations that
on custom solutions     comprehensive         address emerging
    that deliver            offering             healthcare
   ROI & quality                                 challenges




 12/3/2004                               12
How Our Businesses
            Are Currently Performing




12/3/2004                     13
Pharmaceutical Solutions




12/3/2004                    14
FY05 Financial Results –
            Pharmaceutical Solutions
     ($ in millions)                                  Q2                               Six M onths
                                            FY04            FY05                    FY04        FY05
     Revenues
     U.S. direct distribution & services   $ 9,655         $ 11,638   21%          $ 18,990   $ 22,649 19%
     U.S. sales to customers' warehouses     5,058           6,021    19%           10,222      11,938 17%
      Subtotal                              14,713          17,659    20%           29,212      34,587 18%
     Canada distribution & services          1,070           1,258    18%             2,114      2,510 19%
      Total Pharmaceutical Solutions       $ 15,783        $ 18,917   20%          $ 31,326   $ 37,097 18%


     Gross Profit                              509             432 -15%               1,027          992   -3%
      Gross Profit Margin                     3.22%           2.28% (94) bp           3.28%      2.67% (61) bp


     Operating Expense                         294             287    -2%              553           562   2%


     Operating Profit                          222             151 -32%                487           441   -9%
      Operating Profit Margin                 1.40%           0.80% (60) bp           1.55%      1.19% (36) bp



12/3/2004                                                                     15
Pharmaceutical Solutions
                 Q2 Highlights
     Above market U.S. revenue growth of 20%
            First full quarter of VA business with annualized
            revenues in excess of $3.5B, better than expected
            profitability
            AdvancePCS volume of Caremark implemented in
            August with annualized revenues of $2B
     Continued strong growth in Canada of 18%
     Fewer than expected price increases significantly
     reduces operating profit



12/3/2004                                    16
U.S. Pharmaceutical Distribution
         Environment
     35-year evolution in manufacturer economics
            Historical economics evolved to dependence on
            pharmaceutical price inflation for major source of
            compensation
            Changes underway in healthcare may impact
            pharmaceutical pricing
     Customer pricing model established on inflation-
     based profit opportunities




12/3/2004                                    17
Value of Drug Distribution
Industry
  Booz-Allen study shows $10.5 B in added annual
  expense to replicate distributor network/service
McKesson
  Next day delivery to 23,000 pharmacies with 99.1%
  fill rate
  45,000 SKUs
  129,000 invoices per day
  150,000 contracts involving $20 B in annual
  chargebacks
  >$400 M additional invested over the past 4 years

 12/3/2004                         18
McKesson Pharmaceutical
             Product Flow

                   McK         Customer
                   RDC         Warehouse


 Manufacturer


                                Customer
                               Pharmacies




                    McK
                    DCs


12/3/2004                 19
Progress with Manufacturers
 Collaborative strategy designed to deliver more
 predictable core distribution fees based on value
 provided
 Phase 1: Focus on securing an appropriate level of
 compensation with less product sourcing
        Compensation from largest manufacturers still tied to
        the timing and magnitude of price increases
 Phase 2: Focus on maintaining appropriate
 compensation while gaining predictability by
 reducing dependence on price inflation
 Achieve significant progress by January 1 and
 substantially complete the process by March 31,
 2005 fiscal year end

12/3/2004                                 20
Progress with Manufacturers
  PHASE 1:        APPROPRIATE COMPENSATION
  August 2003 to August 2004

                       % Complete                  Result
                                    New IMAs and CDAs reflect value of
                                    service provided
                          80%
  All companies

                                    Compensation still tied to price
                                    inflation
  Largest companies

 PHASE 2:        PREDICTABLE COMPENSATION
 September 2004 to March 2005

                                                 Result
                       % Complete
                                    New agreements based on FFS
 All companies                      and/or guarantees
                         >80%

 Largest companies        25%       About a dozen remaining

12/3/2004                                      21
Pharmaceutical Distribution
          Margin Drivers
            +                                   -
     2% Cash
     2% Cash
     Discount
      Discount
                                            Sell
                                            Sell                         Margin has
                                           Margin
                                           Margin                        fluctuated
                                                                         very little
      Generics                                                            over the
      Generics
                                                                           past 35
                                                                            years
                                        Operating
                                        Operating
                                        Expenses
                                         Expenses
        Buy
         Buy
       Profit*
       Profit*


            * Buy profit includes spe culative buying, IMA s, FFS
12/3/2004                                                           22
Pharmaceutical Solutions
                Operating Margin
Over the past 15 years, we have experienced
significant changes in the marketplace, price
increases ranging between 1.7% and 8.5%, yet
operating margin has fluctuated little between a
narrow range
European distributors that face entirely different
market factors have similar operating margins



   Operating margin for direct store sales has been
    generally between 2% and 2.5% = 1.5% to 2%
             including warehouse sales
12/3/2004                           23
Improve Existing Customer
                   Profitability
 Improving compliance and efficiency across
 customer base
        Focus on securing prime vendor relationships
        exclusively
        Enforce contract terms (e.g., generic compliance)
        Charge for additional services (e.g. emergency
        shipments, minimum order size, etc.)




12/3/2004                                 24
Medical-Surgical Solutions




12/3/2004                      25
FY05 Financial Results –
            Medical-Surgical Solutions
  ($ in millions)                    Q2                            Six Months
                              FY04         FY05                  FY04      FY05

   Revenues               $     716    $     714             $        1,426   $   1,421
                                                     --                                    --


  Gross Profit                   151          162                    297             321 8%
                                                   7%
    Gross Profit Margin       21.13%       22.69% 156 bp          20.85%          22.57% 172 bp


  Operating Profit                25           18 -31%                   51           46 -10%
    Operating Profit Margin    3.53%        2.45% (108) bp            3.58%        3.24% (34) bp




12/3/2004                                                        26
Medical-Surgical Solutions
                 Q2 Highlights
 Continued strong growth from alternate site
 customers
 Quarter’s results impacted primarily by increased
 litigation reserve
 New 3-year, $150 million agreement with Adventist
 Health includes Optyx state-of-the-art analytical
 service




12/3/2004                          27
McKesson Provider
              Technologies




12/3/2004                 28
FY05 Financial Results –
               Provider Technologies
($ in millions)                            Q2                             Six Months
                                    FY04         FY05                   FY04      FY05
Revenues
  Software & software systems $        67    $      50 -26%         $     113    $     101 -11%
  Services                            217          228                    421          451
                                                         5%                                  7%
  Hardware                             27           26 -7%                 48           52   9%
    Total Provider Technologies $     311    $     304 -2%          $     582    $     604   4%

Gross Profit                           152          141 -7%                274          274   --
  Gross Profit Margin               48.65%       46.48% (217) bp        47.04%       45.42% (162) bp


Operating Profit                        37           19 -48%                42          34 -20%
  Operating Profit Margin           11.95%        6.32% (563) bp         7.20%       5.55% (165) bp




  12/3/2004                                                        29
Provider Technologies
                Q2 Highlights
     Software bookings up strongly
     Revenues reflect continued strong demand for
     clinical solutions but complexity of installations
     Percentage of Completion (POC) is increasing as
     a percent of revenue
     Demand for revenue cycle and resource
     management solutions remains flat
     Government focus on HIT may drive future
     growth opportunities


12/3/2004                              30
Summary




12/3/2004             31
What McKesson Represents
Core pharmaceutical business positioned for
sustained growth with a strategy in place to address
industry evolution
Additional businesses poised to take advantage of
new and expanding opportunities in healthcare
Track record of financial performance
       Consistent annual EPS growth despite challenges
       Increasing cash flow
       Strong balance sheet provides financial flexibility
       Commitment to financial transparency


12/3/2004                                  32
Outlook

FY05 expectation: $2.00 to $2.20 per share
       Pharmaceutical Solutions earnings continue to
       depend on price increases through fiscal year end
       Expectation assumes that volume-weighted U.S.
       pharmaceutical price increases in Q3 and Q4 will
       be within the historical range, and that the
       magnitude of price increases will be comparable to
       the recent past



      Create Value for Suppliers, Customers and
                    Shareholders
12/3/2004                              33
12/3/2004   34

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Credit Suisse First Boston Healthcare Conference

  • 1. Credit Suisse First Boston Global Healthcare Conference November 17, 2004
  • 2. John H. Hammergren, Chairman and Chief Executive Officer 12/3/2004 1
  • 3. Safe Harbor Clause Some of the information in this presentation may constitute forward-looking statements that are subject to various uncertainties. These uncertainties could cause actual results to differ materially from those projected or implied. The risk factors associated with those uncertainties are described in the Company’s reports and exhibits filed with the Securities and Exchange Commission. Financial information is presented here in summary form. Full details are provided in the Company’s most recent 10-Q report. All of this information is available at www.mckesson.com. 12/3/2004 2
  • 4. Overview Who We Are Our View of Healthcare How Our Businesses Are Currently Performing 12/3/2004 3
  • 6. McKesson’s Solutions … Building on Distribution Strength Solutions for medication safety Pharmaceutical & medical- surgical distribution to all sites Clinical, financial & resource management for hospitals & IDNs Inpatient automation Specialty Retail pharmacy pharmaceuticals automation Disease management Drug cards for seniors Pharmaceutical 12/3/2004 5 repackaging
  • 7. Our Business Today McKesson McKesson McKesson Provider Technologies Medical- Medical-Surgical Pharmaceutical 63% of health systems #1 in primary care #1 in U.S., Canada, and Mexico 51% of hospitals with #1 in extended 200+ beds care Large Rx repackaging Leader in clinical, Total supply Leading generics provider revenue cycle, solution in acute #1 in retail pharmacy and resource care automation management solutions Private label Specialty distribution & More “Best in KLAS” product offerings patient services for products than any Rapid growth in manufacturers other vendor physician office #1 in medical management #1 in robotic hospital pharmaceuticals software and services for pharmacy dispensing and equipment payors #1 in bedside scanning #1 in disease management for Medicaid agencies 12/3/2004 6
  • 8. Strong, Long-term Customer Relationships with Market Leaders Vanderbilt University Medical Center 12/3/2004 7
  • 9. FY05 Consolidated Financial Results ($ and shares in millions, Q2 Six Months except EPS) FY04 FY05 FY04 FY05 Revenues $ 16,810 $ 19,934 19% $ 33,334 $ 39,121 17% Gross Profit 812 735 -9% 1,598 1,587 -1% Gross Profit Margin 4.83% 3.69% (114) bp 4.79% 4.06% (73) bp Operating Income 227 129 -43% 479 390 -19% Operating Income Margin 1.35% 0.65% (70) bp 1.44% 1.00% (44) bp Net Income 157 86 -45% 312 250 -20% Diluted EPS $ 0.53 $ 0.29 -45% $ 1.05 $ 0.84 -20% Weighted Average Shares 300 300 299 300 12/3/2004 8
  • 10. Our View of Healthcare 12/3/2004 9
  • 11. Trends Driving Healthcare Growth Reduce medical errors Payors taking on more risk Adopt clinical protocols/ Limitations on use of Increased evidence-based medicine managed care tools Focus on pressure on Employer pressures on quality of care payors double-digit premium increases Chronic disease Automation to overcome Continued management labor shortages improvements in Outpatient and Case management Electronic claims and chronic disease operational and Manage high-cost diseases eligibility management administrative in small populations Online prescription and lab efficiency transmissions Streamlined pre-authorization Biotech pipeline expansion Unhappy consumers New drug delivery Better informed consumers Continued use mechanisms of new drugs, Increased Rapid growth in generics but increased consumerism Regulatory pressures on pricing scrutiny pricing 12/3/2004 10
  • 12. Improved U.S. Healthcare by 2010 Informed clinical Informed clinical practice practice CULTURE CULTURE Interconnection Interconnection CHANGE CHANGE Improved safety Improved safety in the in the and efficiency and efficiency delivery of delivery of Personalized care healthcare healthcare Personalized care Population health Population health initiatives initiatives 12/3/2004 11
  • 13. McKesson’s Strategy To bring together clinical knowledge, process expertise, technology, and the resources of a Fortune 16 company to fundamentally change the cost and quality of healthcare. Create long-term Introduce relationships based Sell McKesson’s innovations that on custom solutions comprehensive address emerging that deliver offering healthcare ROI & quality challenges 12/3/2004 12
  • 14. How Our Businesses Are Currently Performing 12/3/2004 13
  • 16. FY05 Financial Results – Pharmaceutical Solutions ($ in millions) Q2 Six M onths FY04 FY05 FY04 FY05 Revenues U.S. direct distribution & services $ 9,655 $ 11,638 21% $ 18,990 $ 22,649 19% U.S. sales to customers' warehouses 5,058 6,021 19% 10,222 11,938 17% Subtotal 14,713 17,659 20% 29,212 34,587 18% Canada distribution & services 1,070 1,258 18% 2,114 2,510 19% Total Pharmaceutical Solutions $ 15,783 $ 18,917 20% $ 31,326 $ 37,097 18% Gross Profit 509 432 -15% 1,027 992 -3% Gross Profit Margin 3.22% 2.28% (94) bp 3.28% 2.67% (61) bp Operating Expense 294 287 -2% 553 562 2% Operating Profit 222 151 -32% 487 441 -9% Operating Profit Margin 1.40% 0.80% (60) bp 1.55% 1.19% (36) bp 12/3/2004 15
  • 17. Pharmaceutical Solutions Q2 Highlights Above market U.S. revenue growth of 20% First full quarter of VA business with annualized revenues in excess of $3.5B, better than expected profitability AdvancePCS volume of Caremark implemented in August with annualized revenues of $2B Continued strong growth in Canada of 18% Fewer than expected price increases significantly reduces operating profit 12/3/2004 16
  • 18. U.S. Pharmaceutical Distribution Environment 35-year evolution in manufacturer economics Historical economics evolved to dependence on pharmaceutical price inflation for major source of compensation Changes underway in healthcare may impact pharmaceutical pricing Customer pricing model established on inflation- based profit opportunities 12/3/2004 17
  • 19. Value of Drug Distribution Industry Booz-Allen study shows $10.5 B in added annual expense to replicate distributor network/service McKesson Next day delivery to 23,000 pharmacies with 99.1% fill rate 45,000 SKUs 129,000 invoices per day 150,000 contracts involving $20 B in annual chargebacks >$400 M additional invested over the past 4 years 12/3/2004 18
  • 20. McKesson Pharmaceutical Product Flow McK Customer RDC Warehouse Manufacturer Customer Pharmacies McK DCs 12/3/2004 19
  • 21. Progress with Manufacturers Collaborative strategy designed to deliver more predictable core distribution fees based on value provided Phase 1: Focus on securing an appropriate level of compensation with less product sourcing Compensation from largest manufacturers still tied to the timing and magnitude of price increases Phase 2: Focus on maintaining appropriate compensation while gaining predictability by reducing dependence on price inflation Achieve significant progress by January 1 and substantially complete the process by March 31, 2005 fiscal year end 12/3/2004 20
  • 22. Progress with Manufacturers PHASE 1: APPROPRIATE COMPENSATION August 2003 to August 2004 % Complete Result New IMAs and CDAs reflect value of service provided 80% All companies Compensation still tied to price inflation Largest companies PHASE 2: PREDICTABLE COMPENSATION September 2004 to March 2005 Result % Complete New agreements based on FFS All companies and/or guarantees >80% Largest companies 25% About a dozen remaining 12/3/2004 21
  • 23. Pharmaceutical Distribution Margin Drivers + - 2% Cash 2% Cash Discount Discount Sell Sell Margin has Margin Margin fluctuated very little Generics over the Generics past 35 years Operating Operating Expenses Expenses Buy Buy Profit* Profit* * Buy profit includes spe culative buying, IMA s, FFS 12/3/2004 22
  • 24. Pharmaceutical Solutions Operating Margin Over the past 15 years, we have experienced significant changes in the marketplace, price increases ranging between 1.7% and 8.5%, yet operating margin has fluctuated little between a narrow range European distributors that face entirely different market factors have similar operating margins Operating margin for direct store sales has been generally between 2% and 2.5% = 1.5% to 2% including warehouse sales 12/3/2004 23
  • 25. Improve Existing Customer Profitability Improving compliance and efficiency across customer base Focus on securing prime vendor relationships exclusively Enforce contract terms (e.g., generic compliance) Charge for additional services (e.g. emergency shipments, minimum order size, etc.) 12/3/2004 24
  • 27. FY05 Financial Results – Medical-Surgical Solutions ($ in millions) Q2 Six Months FY04 FY05 FY04 FY05 Revenues $ 716 $ 714 $ 1,426 $ 1,421 -- -- Gross Profit 151 162 297 321 8% 7% Gross Profit Margin 21.13% 22.69% 156 bp 20.85% 22.57% 172 bp Operating Profit 25 18 -31% 51 46 -10% Operating Profit Margin 3.53% 2.45% (108) bp 3.58% 3.24% (34) bp 12/3/2004 26
  • 28. Medical-Surgical Solutions Q2 Highlights Continued strong growth from alternate site customers Quarter’s results impacted primarily by increased litigation reserve New 3-year, $150 million agreement with Adventist Health includes Optyx state-of-the-art analytical service 12/3/2004 27
  • 29. McKesson Provider Technologies 12/3/2004 28
  • 30. FY05 Financial Results – Provider Technologies ($ in millions) Q2 Six Months FY04 FY05 FY04 FY05 Revenues Software & software systems $ 67 $ 50 -26% $ 113 $ 101 -11% Services 217 228 421 451 5% 7% Hardware 27 26 -7% 48 52 9% Total Provider Technologies $ 311 $ 304 -2% $ 582 $ 604 4% Gross Profit 152 141 -7% 274 274 -- Gross Profit Margin 48.65% 46.48% (217) bp 47.04% 45.42% (162) bp Operating Profit 37 19 -48% 42 34 -20% Operating Profit Margin 11.95% 6.32% (563) bp 7.20% 5.55% (165) bp 12/3/2004 29
  • 31. Provider Technologies Q2 Highlights Software bookings up strongly Revenues reflect continued strong demand for clinical solutions but complexity of installations Percentage of Completion (POC) is increasing as a percent of revenue Demand for revenue cycle and resource management solutions remains flat Government focus on HIT may drive future growth opportunities 12/3/2004 30
  • 33. What McKesson Represents Core pharmaceutical business positioned for sustained growth with a strategy in place to address industry evolution Additional businesses poised to take advantage of new and expanding opportunities in healthcare Track record of financial performance Consistent annual EPS growth despite challenges Increasing cash flow Strong balance sheet provides financial flexibility Commitment to financial transparency 12/3/2004 32
  • 34. Outlook FY05 expectation: $2.00 to $2.20 per share Pharmaceutical Solutions earnings continue to depend on price increases through fiscal year end Expectation assumes that volume-weighted U.S. pharmaceutical price increases in Q3 and Q4 will be within the historical range, and that the magnitude of price increases will be comparable to the recent past Create Value for Suppliers, Customers and Shareholders 12/3/2004 33
  • 35. 12/3/2004 34