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DNA Profiling to Support Your Health
“Health is not everything, but without health,
 everything is nothing…”
 Schopenhauer
Your Perception of DNA

> Crime shows and catching criminals
> Human genome mapped
> Predicting disease?
DNA Will
  Change
  Medicine and
  Healthcare
> We are on the brink of one of
  the most significant events in
  medicine and healthcare.

> A paradigm shift.
A New Era

> Personalised medicine

> Preventive healthcare

> Integrated healthcare

> Integration of advanced technology into all
  aspects of healthcare
DNA Profiling
> Are more genes better?

> We have approx 25,000 genes and 3 million
  base pair combinations.

> Major challenge is to take all this information and
  make it clinically relevant.
Fitgenes Philosophy

> Not disease predictive.

> Fitgenes focuses on genes that impact on
  function.

> Fitgenes focuses on genes that we can modify.
Gene Expression

Genes that enhance health and function we want
to ‘turn up’.
                        e.g. antioxidant genes that
                        produce our antioxidant
                        enzymes.
Gene Expression
Genes that negatively impact on health and
function we want to ‘turn down’.

                   e.g. inflammatory genes that
                   produce inflammatory
                   cytokines that can cause
                   damage.
Gene Categories


› Inflammation

› Cellular Health and Oxidative Stress

› Cardiovascular Health

› Fat Metabolism and Weight Management

› Vitamin D Receptor Function
Inflammation
Inflammation
Inflammation
Inflammation and Disease Risk
Alzheimer’s              Osteoporosis
Ankylosing Spondylitis   Periodontal disease
Asthma                   Psoriasis
Atherosclerosis          Rheumatoid Arthritis
Autoimmune Disease       Rhinosinusitis
Bronchitis               Schizophrenia
Cancer                   Urinary Tract Issues
Cardiovascular Disease
Depression
Diabetes
IBS
Insulin Resistance
Macular Degeneration
Are You Inflamed?
> Sore / aching muscles and joints

> Delayed onset muscle soreness after exercise

> Prone to injuries when exercising

> Fluid retention / swollen fingers and ankles, especially
  during or after exercise
> Inflamed skin, skin disorders

> Diarrhea

> Current infection, injury, broken bone

> Overweight
Oxidative Stress
Oxidative Stress
Oxidative Stress and Disease Risk
›   Ageing
›   Alzheimer’s
›   Atherosclerosis
›   Cancer
›   Cardiovascular Disease
›   Diabetes
›   Hypertension
›   Insulin Resistance
›   Liver Damage
›   Melanoma
Do you have Oxidative Stress?
>   Insulin Resistant
>   Diabetic
>   Raised liver enzymes
>   Getting older
>   Age spots
>   Had chemotherapy
>   Had radiotherapy
>   Inflamed
>   Overweight
Cardiovascular Health
Cardiovascular Health
Cardiovascular Health
Health and Weight




It is estimated that 75% of health and life expectancy after age 40 is
modifiable.

Losing just 10% of your body weight can add 10 years to your life.
Health and Weight


A Federal Government
Report May 2009 titled
“Weighing it up –
Obesity in Australia”
stated:


› Environmental and Lifestyle Factors contribute
  approximately 30% to weight.

› Genetics contributes the other 70%.

› Other studies show a 50/50 split
  genetics/environment
Weight Management
Factors Influencing Weight Loss

› Diet
› Exercise
› Hormones
   - Glucose, Insulin, Glucagon, Leptin, Adrenaline, Cortisol
› Inflammation
› Liver Function
› Toxicity Levels



Genetics influences all of the above
Your Genes:
What is Your
Genetic Playing
Field?
Benefits of a DNA Profile
> Make the BEST Choices for YOUR Health.

> Learn the best choices you can make, based
  upon your genome, to help you achieve optimal
  health and well being.
> Choose the supplements, foods, exercise and
  lifestyle habits that best support YOUR health.
Preventive Healthcare
> Don’t wait to get sick before you focus on your
  health.

> Genetic knowledge has the potential to shift
  healthcare from a disease focused model to
  prevention based medicine.

> Gain a greater understanding of disease
  processes and your genetic ability to control
  these processes.

> Learn how to obtain good health and maintain
  health.
Positive Health Outcomes

› Healthy weight

› Improved energy

› Improved fitness

› Improved sleep

› Better health
12 week program to
better health and wellbeing
Fast Track to Health Programs
Choice of Genetic Profiles
Genetic Profile:

>General Health
>Advanced
Choice of Pathology

> Basic
> Comprehensive
> Advanced
Women’s Health
                                 Initiative Study
                                 An opportunity to be part
                                 of a new approach to
                                 health care.




> You can be one of the first people in the world to
  undertake a comprehensive DNA based nutrigenomic
  program with advanced pathology screening.
Women’s Health
Initiative
Participant Overview

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12 Ways to Increase Your Influence at Work
 

Fitgenes DNA Profiling to Support Health

  • 1. DNA Profiling to Support Your Health
  • 2. “Health is not everything, but without health, everything is nothing…” Schopenhauer
  • 3. Your Perception of DNA > Crime shows and catching criminals > Human genome mapped > Predicting disease?
  • 4. DNA Will Change Medicine and Healthcare > We are on the brink of one of the most significant events in medicine and healthcare. > A paradigm shift.
  • 5. A New Era > Personalised medicine > Preventive healthcare > Integrated healthcare > Integration of advanced technology into all aspects of healthcare
  • 6. DNA Profiling > Are more genes better? > We have approx 25,000 genes and 3 million base pair combinations. > Major challenge is to take all this information and make it clinically relevant.
  • 7. Fitgenes Philosophy > Not disease predictive. > Fitgenes focuses on genes that impact on function. > Fitgenes focuses on genes that we can modify.
  • 8. Gene Expression Genes that enhance health and function we want to ‘turn up’. e.g. antioxidant genes that produce our antioxidant enzymes.
  • 9. Gene Expression Genes that negatively impact on health and function we want to ‘turn down’. e.g. inflammatory genes that produce inflammatory cytokines that can cause damage.
  • 10. Gene Categories › Inflammation › Cellular Health and Oxidative Stress › Cardiovascular Health › Fat Metabolism and Weight Management › Vitamin D Receptor Function
  • 14. Inflammation and Disease Risk Alzheimer’s Osteoporosis Ankylosing Spondylitis Periodontal disease Asthma Psoriasis Atherosclerosis Rheumatoid Arthritis Autoimmune Disease Rhinosinusitis Bronchitis Schizophrenia Cancer Urinary Tract Issues Cardiovascular Disease Depression Diabetes IBS Insulin Resistance Macular Degeneration
  • 15. Are You Inflamed? > Sore / aching muscles and joints > Delayed onset muscle soreness after exercise > Prone to injuries when exercising > Fluid retention / swollen fingers and ankles, especially during or after exercise > Inflamed skin, skin disorders > Diarrhea > Current infection, injury, broken bone > Overweight
  • 18. Oxidative Stress and Disease Risk › Ageing › Alzheimer’s › Atherosclerosis › Cancer › Cardiovascular Disease › Diabetes › Hypertension › Insulin Resistance › Liver Damage › Melanoma
  • 19. Do you have Oxidative Stress? > Insulin Resistant > Diabetic > Raised liver enzymes > Getting older > Age spots > Had chemotherapy > Had radiotherapy > Inflamed > Overweight
  • 23. Health and Weight It is estimated that 75% of health and life expectancy after age 40 is modifiable. Losing just 10% of your body weight can add 10 years to your life.
  • 24. Health and Weight A Federal Government Report May 2009 titled “Weighing it up – Obesity in Australia” stated: › Environmental and Lifestyle Factors contribute approximately 30% to weight. › Genetics contributes the other 70%. › Other studies show a 50/50 split genetics/environment
  • 26. Factors Influencing Weight Loss › Diet › Exercise › Hormones - Glucose, Insulin, Glucagon, Leptin, Adrenaline, Cortisol › Inflammation › Liver Function › Toxicity Levels Genetics influences all of the above
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  • 29. Your Genes: What is Your Genetic Playing Field?
  • 30. Benefits of a DNA Profile > Make the BEST Choices for YOUR Health. > Learn the best choices you can make, based upon your genome, to help you achieve optimal health and well being. > Choose the supplements, foods, exercise and lifestyle habits that best support YOUR health.
  • 31. Preventive Healthcare > Don’t wait to get sick before you focus on your health. > Genetic knowledge has the potential to shift healthcare from a disease focused model to prevention based medicine. > Gain a greater understanding of disease processes and your genetic ability to control these processes. > Learn how to obtain good health and maintain health.
  • 32. Positive Health Outcomes › Healthy weight › Improved energy › Improved fitness › Improved sleep › Better health
  • 33. 12 week program to better health and wellbeing Fast Track to Health Programs
  • 34. Choice of Genetic Profiles Genetic Profile: >General Health >Advanced
  • 35. Choice of Pathology > Basic > Comprehensive > Advanced
  • 36. Women’s Health Initiative Study An opportunity to be part of a new approach to health care. > You can be one of the first people in the world to undertake a comprehensive DNA based nutrigenomic program with advanced pathology screening.