Geriatric%20 Medicine%20 %20 Dr.%20 Cefalu

Clinical Pharmacological Issues in the Elderly Charles A. Cefalu MD, M Professor and Chief, Section of Geriatric Medicine Department of Fam. Med, LSUHSC, New Orleans, La.

Evaluation for Possible Polypharmacy ,[object Object],[object Object],[object Object]

Increased Medication Use and Perceived Health in the Oldest Old ,[object Object],[object Object],[object Object]

Factors Related to Adverse Drug Drug Reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Factors Related to Increased Number of Adverse Drug Reactions, Cont’d ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Normal Changes of Aging ,[object Object],[object Object],[object Object],[object Object],[object Object]

Normal Physiological Changes of the Organ Systems ,[object Object],[object Object],[object Object],[object Object]

Normal Changes of Aging-Hepatic ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmaceutical Agents That Require Hepatic Metabolism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmaceutical Agents That Require Hepatic Metabolism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

The Cytochrome System ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Particular Agents of Concern in the Elderly-highly bound to protein ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Normal Changes of Aging-Renal ,[object Object],[object Object],[object Object]

Creatinine Clearance Calculation ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmaceutical Agents Primarily Eliminated In the Kidneys Requiring Dosage Adjustment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Inappropriate Prescribing of Renally Excreted Agents in LTC ,[object Object],[object Object],[object Object]

Aminoglycoside Dosing in the Elderly With Impaired Renal Function ,[object Object],[object Object]

“Good Rule of Thumb” ,[object Object]

Physiological changes of the GI Tract ,[object Object],[object Object],[object Object]

CNS Changes with Aging ,[object Object],[object Object],[object Object],[object Object]

Anticholinergic Agents ,[object Object],[object Object],[object Object],[object Object]

Anti-cholinergic Agents-continued ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Common Clinical Conditions Necessitate Adjustment of Dosage in the Elderly: ,[object Object],[object Object],[object Object],[object Object],[object Object]

Anorexia and Aging ,[object Object],[object Object],[object Object]

Anorexia-Drug Induced: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Specific High Risk Drug Categories

Screening for potential toxicity of prescription drugs-H2 Blockers: ,[object Object],[object Object],[object Object],[object Object]

H2 Blockers-continued ,[object Object],[object Object]

High Risk Drugs-Beta Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],.

Beta Blockers-continued ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Antihypertensives that cause Postural Hypotension or Sedation: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Diuretics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Diuretics-continued ,[object Object],[object Object],[object Object],[object Object]

Diuretics-References ,[object Object],[object Object],[object Object],[object Object]

Major and Minor Tranquilizers* and Hypnotics: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Oral Hypoglycemics: ,[object Object],[object Object]

Lanoxin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

NSAIDs*: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

“ Tips” for Safe Traditional NSAID Use ,[object Object],[object Object],[object Object],[object Object],[object Object]

Narcotics: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Theophylline Adverse Reactions: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Oxybutynin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Muscle Relaxers: ,[object Object],[object Object],[object Object],[object Object],[object Object]

Ophthalmologic Preparations ,[object Object],[object Object]

List Of Inappropriate Drugs In Elderly-Journal of American Medical Association-July 27, 1994; Archives of Internal Medicine-July 28, 1997 and 2003

Inappropriate Drugs in Elderly: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Inappropriate Drugs in Elderly-Cont,d ,[object Object],[object Object],[object Object],[object Object]

Inappropriate Drugs in Elderly-Cont,d ,[object Object],[object Object],[object Object],[object Object],[object Object]

Inappropriate Drugs in Elderly-Cont,d ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pain Pill Use by Elders ,[object Object],[object Object]

Inappropriate Drugs in Elderly-Cont,d ,[object Object]

Screening for Toxicity of OTC Drugs ,[object Object],[object Object],[object Object]

Screening for Toxicity-OTC Drugs-Cont. ,[object Object],[object Object],[object Object]

Rules for Prescribing to the Elderly ,[object Object],[object Object],[object Object],[object Object]

Rules, cont’d ,[object Object],[object Object],[object Object],[object Object],[object Object]

Rules, cont’d ,[object Object],[object Object],[object Object],[object Object]

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