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Respiratory failure MBBS.weebly.com
Male, 32 Fever, cough with sputum for 3 days No finding on physical examination Diagnosis : pneumonia  X - ray : shadow in left lower lobe  August 16, 2003 August 20, 2003 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intubation via mouth tracheotomy Monitoring and ventilation
Contents 0f outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction (cont.) ,[object Object],[object Object],[object Object],[object Object]
Definition   ,[object Object],[object Object],[object Object],[object Object]
Classification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Classification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Etiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Respiratory Pump Failure (泵衰竭) ,[object Object],[object Object],[object Object]
Lung Failure (肺衰竭) ,[object Object],[object Object],[object Object],[object Object]
Mechanisms & Pathophysiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mechanisms of hypoxemia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],25  20  15  10  5  肺泡分压 (kPa) 0  2  4  6  8  10 肺泡通气量 (l/min) P A CO2 P A O2 P A C O 2  =0.863*VC O2 /VA
Mechanisms of hypoxemia ––   Diffusion abnormality ( 弥散障碍 ) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],100 80 60 40 动脉氧分压 0.25  0.5  0.75 血液通过肺泡毛细血管时间
Mechanisms of hypoxemia ,[object Object],[object Object],V/Q=0.8 V/Q>0.8 V/Q<0.8 Q > V (A-V shunt) Normal V > Q (dead space effect)
( 二 ) 通气 / 血流比例  V/Q 肺泡死腔通气 V/Q > 0.8 静 - 动脉分流 V/Q < 0.8 正常通气 / 血流 V/Q 0.8 VD  PaCO 2 - PeCO 2 VT  PaCO 2 Qs  CcO 2   - CaO 2 Q T   CcO 2   - CvO 2 V A   4.2L(R2.1, L2.1) Q  5.0L(R2.5, L2.5) 见于肺不张, ARDS 见于 COPD 正常 Mechanisms of hypoxemia
Mechanisms of hypoxemia ,[object Object],[object Object],800 100 20 10 肺泡氧分压 2  4  6  8  10 肺泡通气量 (l/min) 400 动脉氧分压 (kPa)
Mechanisms of hypercapnia ,[object Object],[object Object],[object Object]
Influence of hypoxemia  Central nervous system   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Influence of hypoxemia Cardiovascular system ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Influence of hypoxemia Respiratory system
Influence of hypoxemia haematological system   ,[object Object],[object Object]
Influence of hypoxemia Renal & Digestive system ,[object Object],[object Object]
Influence of hypercapnia  Central nervous system ,[object Object],[object Object],[object Object],[object Object]
Influence of hypercapnia   Cardiovascular system ,[object Object],[object Object],[object Object],[object Object],[object Object]
Influence of hypercapnia   Respiratory system ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
pH  pH     26.6mmHg
Influence of hypercapnia urinary  system ,[object Object],[object Object],[object Object]
Influence of hypoxemia & hypercapnia Acid-base balance and electrolytes ,[object Object],[object Object],[object Object],[object Object],[object Object],pH = HCO 3 - PaCO 2
Clinical manifestation Acute respiratory failure (1) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Clinical manifestation Acute respiratory failure (2)
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Clinical manifestation Acute respiratory failure (3)
Clinical manifestation Chronic respiratory failure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnostic criteria   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnostic criteria   The acute respiratory distress syndrome (ARDS)   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment   (outline of principle) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Etiology Management ,[object Object],[object Object],[object Object]
Causes of Upper Airway Obstruction ,[object Object],[object Object],[object Object],[object Object]
Treatment   Keep airway open  保持气道通畅 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
A: Airway   ( 气道通畅吗? ) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Maneuvers to Open the Airway ,[object Object],[object Object],[object Object]
Treatment   Keep airway open 保持气道通畅 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intubation Procedure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intubation Procedure ,[object Object],[object Object],[object Object],[object Object]
CO 2  Detection  测定证实
B: Breathing  呼吸 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Barrier Breathing Devices 呼吸保护屏障装置
B: Breathing  呼吸 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
B: Breathing  呼吸 Airway Alternatives “ Fast-Trach” LMA (Laryngeal Mask Airway)
C: Circulation  循环 ,[object Object],[object Object],[object Object],[object Object]
D: Diagnosis  诊断 ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Treatment Oxygen therapy ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Oxygen therapy ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Treatment Oxygen therapy
Nasal cannula/prongs 鼻导管吸氧 ,[object Object]
Simple oxygen mask 常规面罩 ,[object Object],[object Object]
Venturi mask  Venturi 面罩 ,[object Object]
Treatment Oxygen therapy ,[object Object],[object Object],[object Object],[object Object]
Treatment Ensure adequate ventilation, correct CO2 retention ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Non-invasive positive pressure ventilation, NIPPV ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Different kind of masks  各款口鼻面罩
Treatment Mechanical ventilation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Management of electrolyte and acid-base disturbance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thank you!

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12.Respiratory Failure

  • 2.
  • 3. Intubation via mouth tracheotomy Monitoring and ventilation
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18. ( 二 ) 通气 / 血流比例 V/Q 肺泡死腔通气 V/Q > 0.8 静 - 动脉分流 V/Q < 0.8 正常通气 / 血流 V/Q 0.8 VD PaCO 2 - PeCO 2 VT PaCO 2 Qs CcO 2 - CaO 2 Q T CcO 2 - CvO 2 V A 4.2L(R2.1, L2.1) Q 5.0L(R2.5, L2.5) 见于肺不张, ARDS 见于 COPD 正常 Mechanisms of hypoxemia
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29. pH  pH  26.6mmHg
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47. CO 2 Detection 测定证实
  • 48.
  • 49. Barrier Breathing Devices 呼吸保护屏障装置
  • 50.
  • 51. B: Breathing 呼吸 Airway Alternatives “ Fast-Trach” LMA (Laryngeal Mask Airway)
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.
  • 61.
  • 62.
  • 63.
  • 64. Different kind of masks 各款口鼻面罩
  • 65.
  • 66.