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Ovarian Tumors: Diagnosis or Prognosis? ,[object Object],[object Object]
Introduction
Prognosis Has a Bleak Picture: ,[object Object],[object Object],[object Object]
To Improve Prognosis: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Early disgnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Who Are at Risk? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Who are at risk? ,[object Object],[object Object],[object Object],[object Object]
Who Are at Risk? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Who Are at Risk? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
To sum up: Who Are at Risk? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Symptomatology. ,[object Object],[object Object],[object Object]
Screening Tests: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Tumor Markers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CA-125 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Imaging ,[object Object],[object Object],[object Object],[object Object]
Let us look in US
US…Screening Score ,[object Object],[object Object],[object Object]
Table (1) Scoring for US appearance of ovaries Appearance Score Atrophic 0 Volume >8cm. 1 Simple anechoic <3cm 1 Simple anechoic <5cm 2 Simple anechoic >5cm 3 Multilocular <5cm 2 Multilocular >5cm 3 Complex, cyst with echoic shadows. 4 Solid cyst (solid areas >50%) 5
Table (2), Score for Women ’s History History Score Family history of ovarian carcinoma 2 Past or family history of genital, breast or colon 1 Negative history of oral contraceptive 1 Nulligravida 1
Table(3), Scoring of women, 1 st  Scan Result TVS finding TVS score Other Ovary Family History Malignant History OCP History Total Score Simple cyst < 3cm (Persistent) 1$ 0 2 0 1 4 Simple cyst < 5cm 1 1 0 1 0 3 Simple cyst =>5cm 1 0 0 0 0 1 Multiloc < 5cm  1 1 0 0 1 3 Multiloc =>5cm 2$ 2 2 0 1 7 Complex 2$ 0 0 1 0 3 Solid 2 0 0 0 0 2
Table (4): Surgical Results of Cases Operated Upon After the First Examination (N=198 ). TVS result No. Result Volume > 8Cm3 1 Not operated Simple cyst < 3cm (persistent) 4 1 Malignant 3 Benign Simple cyst < 5cm 5 2 Malignant  1 inflammatory 2Benign Simple cyst =>5cm 3 3 simple serous Multilocucyst < 5cm 1 Inflammatory  Multilocular cyst =>5cm 2 1 malignant  1 inflammatory Complex cyst 1 Malignant Solid cyst 1 Malignant Total 18
Table (5): cases with proved malignancy.   TVS Surgical stage Path. Grade Pathology Simple cyst < 3cm 1ai I Cystadenocarcinoma Simple <5cm 1ai I Mucinous carcinoma Simple <5cm 1aii I Cystadenocarcinoma Multiloc. >5cm 1bi II Endometroid Complex 1ai I Cystadenocarcinoma Solid cyst 1c I Endometroid
Table (6): Surgical results after one year (N 185) TVS Result  No.  Surgical result Volume >8cm3 1  Not operated Simple Cyst < 3cm (persistent) 2 Simple serous Simple < 5cm 2 Simple serous Simple cyst => 5cm 0 Multilocular cyst <5cm 0  Multilocular cyst =>5cm 0  Complex cyst 0 Solid cyst 0 Total 5
Table(7), Scoring of women after one year, N (185) TVS finding TVS score Other Ovary Family History Malignant History OCP History Total Score Simple cyst < 3cm (Persistent) 1 0 2 0 1 4 Simple cyst < 5cm 2 2 0 0 0 0 0 0 1 1 3
Table (8): Comparison Between Cases With Proved Malignancy and Cases With Benign Lesions (first Scan). Lesion No. Min Score Max score  Mean SD Malignant 6 3 12 6.33 3.1 Benign 15 1 4 2.93 0.88
Mean and SD of total score of Benign and malignant lesions (first scan)
Detection of abnormal, benign and malignant lesion (first Scan) in  1 st  scan
Detection of Abnormal, Benign and malignant lesion in 2 nd  scan.
Cytology ,[object Object],[object Object]
Pelvic Examination. ,[object Object],[object Object]
Prevention; Prophylactic oophorectomy ,[object Object],[object Object],[object Object],[object Object]
Improve Existing Treatment. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Staging: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Staging, (Surgical) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Surg Procedure. ,[object Object],[object Object],[object Object]
Postoperative Treatment. ,[object Object],[object Object],[object Object],[object Object]
Adjuvant Therapy. ,[object Object],[object Object],[object Object],[object Object]
Monitoring ,[object Object],[object Object],[object Object],[object Object]
Monitoring ,[object Object],[object Object],[object Object],[object Object]
Future ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object]
Epilog. ,[object Object],[object Object]
If you think Prognosis ,[object Object]
If you think Survival or Mortality ,[object Object]
Thank you

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Ovarian Tumors, Diagnosis Or Prognosis

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  • 16. Let us look in US
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  • 18. Table (1) Scoring for US appearance of ovaries Appearance Score Atrophic 0 Volume >8cm. 1 Simple anechoic <3cm 1 Simple anechoic <5cm 2 Simple anechoic >5cm 3 Multilocular <5cm 2 Multilocular >5cm 3 Complex, cyst with echoic shadows. 4 Solid cyst (solid areas >50%) 5
  • 19. Table (2), Score for Women ’s History History Score Family history of ovarian carcinoma 2 Past or family history of genital, breast or colon 1 Negative history of oral contraceptive 1 Nulligravida 1
  • 20. Table(3), Scoring of women, 1 st Scan Result TVS finding TVS score Other Ovary Family History Malignant History OCP History Total Score Simple cyst < 3cm (Persistent) 1$ 0 2 0 1 4 Simple cyst < 5cm 1 1 0 1 0 3 Simple cyst =>5cm 1 0 0 0 0 1 Multiloc < 5cm 1 1 0 0 1 3 Multiloc =>5cm 2$ 2 2 0 1 7 Complex 2$ 0 0 1 0 3 Solid 2 0 0 0 0 2
  • 21. Table (4): Surgical Results of Cases Operated Upon After the First Examination (N=198 ). TVS result No. Result Volume > 8Cm3 1 Not operated Simple cyst < 3cm (persistent) 4 1 Malignant 3 Benign Simple cyst < 5cm 5 2 Malignant 1 inflammatory 2Benign Simple cyst =>5cm 3 3 simple serous Multilocucyst < 5cm 1 Inflammatory Multilocular cyst =>5cm 2 1 malignant 1 inflammatory Complex cyst 1 Malignant Solid cyst 1 Malignant Total 18
  • 22. Table (5): cases with proved malignancy. TVS Surgical stage Path. Grade Pathology Simple cyst < 3cm 1ai I Cystadenocarcinoma Simple <5cm 1ai I Mucinous carcinoma Simple <5cm 1aii I Cystadenocarcinoma Multiloc. >5cm 1bi II Endometroid Complex 1ai I Cystadenocarcinoma Solid cyst 1c I Endometroid
  • 23. Table (6): Surgical results after one year (N 185) TVS Result No. Surgical result Volume >8cm3 1 Not operated Simple Cyst < 3cm (persistent) 2 Simple serous Simple < 5cm 2 Simple serous Simple cyst => 5cm 0 Multilocular cyst <5cm 0 Multilocular cyst =>5cm 0 Complex cyst 0 Solid cyst 0 Total 5
  • 24. Table(7), Scoring of women after one year, N (185) TVS finding TVS score Other Ovary Family History Malignant History OCP History Total Score Simple cyst < 3cm (Persistent) 1 0 2 0 1 4 Simple cyst < 5cm 2 2 0 0 0 0 0 0 1 1 3
  • 25. Table (8): Comparison Between Cases With Proved Malignancy and Cases With Benign Lesions (first Scan). Lesion No. Min Score Max score Mean SD Malignant 6 3 12 6.33 3.1 Benign 15 1 4 2.93 0.88
  • 26. Mean and SD of total score of Benign and malignant lesions (first scan)
  • 27. Detection of abnormal, benign and malignant lesion (first Scan) in 1 st scan
  • 28. Detection of Abnormal, Benign and malignant lesion in 2 nd scan.
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