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Chapter 45 Hormones and the Endocrine System
Overview: The Body’s Long-Distance Regulators ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Concept 45.1: Hormones and other signaling molecules bind to target receptors, triggering specific response pathways ,[object Object],[object Object]
Types of Secreted Signaling Molecules ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hormones ,[object Object],[object Object],[object Object],[object Object]
Local Regulators ,[object Object],[object Object],[object Object],[object Object],[object Object]
Neurotransmitters and Neurohormones ,[object Object],[object Object],[object Object]
[object Object]
Pheromones ,[object Object],[object Object]
Chemical Classes of Hormones ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathway for Water-Soluble Hormones ,[object Object],Animation: Water-Soluble Hormone
[object Object],[object Object],[object Object]
Fig. 45-6-2 cAMP Second messenger Adenylyl cyclase G protein-coupled receptor ATP GTP G protein Epinephrine Inhibition of glycogen synthesis Promotion of glycogen breakdown Protein kinase A
Pathway for Lipid-Soluble Hormones ,[object Object],[object Object],[object Object],Animation: Lipid-Soluble Hormone
Fig. 45-7-2 Hormone (estradiol) Hormone-receptor complex Plasma membrane Estradiol (estrogen) receptor DNA Vitellogenin mRNA for vitellogenin
Multiple Effects of Hormones ,[object Object],[object Object],[object Object],[object Object],[object Object]
Fig. 45-8-2 Glycogen deposits   receptor Vessel dilates. Epinephrine (a) Liver cell Epinephrine   receptor Glycogen breaks down and glucose is released. (b) Skeletal muscle blood vessel Same receptors but different intracellular proteins (not shown) Epinephrine   receptor Different receptors Epinephrine   receptor Vessel constricts. (c) Intestinal blood vessel
Concept 45.2: Negative feedback and antagonistic hormone pairs are common features of the endocrine system ,[object Object]
Simple Hormone Pathways ,[object Object]
[object Object],[object Object]
Insulin and Glucagon: Control of Blood Glucose ,[object Object],[object Object]
Fig. 45-12-5 Homeostasis: Blood glucose level (about 90 mg/100 mL) Glucagon STIMULUS: Blood glucose level falls. Alpha cells of pancreas release glucagon. Liver   breaks down   glycogen and   releases glucose. Blood glucose level rises. STIMULUS: Blood glucose level rises. Beta cells of pancreas release insulin into the blood. Liver takes up glucose and stores it as glycogen. Blood glucose level declines. Body cells take up more glucose. Insulin
Target Tissues for Insulin and Glucagon ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Concept 45.3: The endocrine and nervous systems act individually and together in regulating animal physiology ,[object Object]
Coordination of Endocrine and Nervous Systems in Vertebrates ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Posterior Pituitary Hormones ,[object Object],Fig. 45-15 Posterior pituitary Anterior pituitary Neurosecretory cells of the hypothalamus Hypothalamus Axon HORMONE Oxytocin ADH Kidney tubules TARGET Mammary glands, uterine muscles
[object Object],[object Object],[object Object],[object Object]
Anterior Pituitary Hormones ,[object Object],[object Object]
Hormone Cascade Pathways ,[object Object],[object Object],[object Object]
Tropic Hormones ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Growth Hormone ,[object Object],[object Object],[object Object],[object Object]
Adrenal Hormones: Response to Stress ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fig. 45-21 Stress Adrenal gland Nerve cell Nerve signals Releasing hormone Hypothalamus Anterior pituitary Blood vessel ACTH Adrenal cortex Spinal cord Adrenal medulla Kidney (a) Short-term stress response (b) Long-term stress response Effects of epinephrine and norepinephrine: 2. Increased blood pressure 3. Increased breathing rate 4. Increased metabolic rate 1. Glycogen broken down to glucose; increased blood glucose 5. Change in blood flow patterns, leading to increased   alertness and decreased digestive, excretory, and   reproductive system activity Effects of mineralocorticoids: Effects of glucocorticoids: 1. Retention of sodium   ions and water by   kidneys 2. Increased blood   volume and blood   pressure 2. Possible suppression of   immune system 1. Proteins and fats broken down   and converted to glucose, leading   to increased blood glucose
Gonadal Sex Hormones ,[object Object],[object Object]
[object Object],[object Object]
You should now be able to: ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Chapter 46 Animal Reproduction Animal Reproduction Chapter 46
Concept 46.1: Both asexual and sexual reproduction occur in the animal kingdom ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Sexual Reproduction: An Evolutionary Enigma ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Reproductive Cycles and Patterns ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Concept 46.4: The timing and pattern of meiosis in mammals differ for males and females ,[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Fig. 46-12g Primordial germ cell Mitotic divisions Oogonium Mitotic divisions Primary oocyte (present at birth), arrested in prophase of meiosis  I Completion of meiosis  I   and onset of meiosis  II Secondary oocyte, arrested at metaphase of meiosis  II First polar body Ovulation, sperm entry Completion of meiosis  II Second polar body Fertilized egg 2 n 2 n n n n n In embryo
Fig. 46-12c Primordial germ cell in embryo Mitotic divisions Spermatogonial stem cell Mitotic divisions Spermatogonium Mitotic divisions Primary spermatocyte Meiosis  I Secondary spermatocyte Meiosis  II Early spermatid Differentiation (Sertoli cells provide nutrients) Sperm 2 n 2 n 2 n n n n n n n n n n n
Chapter 47  Animal Development
Concept 47.1: After fertilization, embryonic development proceeds through cleavage, gastrulation, and organogenesis ,[object Object],[object Object],[object Object],[object Object]
Fertilization ,[object Object],[object Object]
The Acrosomal Reaction ,[object Object],[object Object]
[object Object]
Activation of the Egg ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Cleavage ,[object Object],[object Object],[object Object]
Fig. 47-6 (a) Fertilized egg (b) Four-cell stage (c) Early blastula (d) Later blastula
[object Object],[object Object],[object Object]
[object Object]
Fig. 47-8-6 Blastula (cross section) Blastocoel Animal pole 4-cell stage forming 2-cell stage forming Zygote 8-cell stage Vegetal pole 0.25 mm 0.25 mm
Gastrulation ,[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Fig. 47-10-4 Future ectoderm Key Future endoderm Future mesoderm SURFACE VIEW Animal pole Vegetal pole Early gastrula Blastopore Blastocoel Dorsal lip of blasto- pore CROSS SECTION Dorsal lip of blastopore Late gastrula Blastocoel shrinking Archenteron Blastocoel remnant Archenteron Blastopore Blastopore Yolk plug Ectoderm Mesoderm Endoderm
Chapter 48 Neurons, Synapses, and Signaling
Overview: Lines of Communication ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Introduction to Information Processing ,[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Neuron Structure and Function ,[object Object],[object Object],[object Object],[object Object]
Fig. 48-4 Dendrites Stimulus Nucleus Cell body Axon hillock Presynaptic cell Axon Synaptic terminals Synapse Postsynaptic cell Neurotransmitter
[object Object],[object Object]
[object Object],[object Object]
Concept 48.2: Ion pumps and ion channels maintain the resting potential of a neuron ,[object Object],[object Object],[object Object]
Formation of the Resting Potential ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Animation: Resting Potential
Production of Action Potentials ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conduction Speed ,[object Object],[object Object],[object Object]
Fig. 48-12 Axon Schwann cell Myelin sheath Nodes of Ranvier Node of Ranvier Schwann cell Nucleus of Schwann cell Layers of myelin Axon 0.1 µm
Fig. 48-12a Axon Myelin sheath Schwann cell Nodes of Ranvier Schwann cell Nucleus of Schwann cell Node of Ranvier Layers of myelin Axon
[object Object],[object Object]
Concept 48.4: Neurons communicate with other cells at synapses ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Animation: Synapse
Fig. 48-15 Voltage-gated Ca 2+  channel Ca 2+ 1 2 3 4 Synaptic cleft Ligand-gated ion channels Postsynaptic membrane Presynaptic membrane Synaptic vesicles containing neurotransmitter 5 6 K + Na +
Generation of Postsynaptic Potentials ,[object Object],[object Object]
Chapter 49 Nervous Systems
Concept 49.1: Nervous systems consist of circuits of neurons and supporting cells ,[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Concept 49.2: The vertebrate brain is regionally specialized ,[object Object],[object Object]
The Brainstem ,[object Object],[object Object]
[object Object],[object Object],[object Object]
Arousal and Sleep ,[object Object],[object Object],[object Object],[object Object]
Chapter 50 Sensory and Motor Mechanisms
Concept 50.1: Sensory receptors transduce stimulus energy and transmit signals to the central nervous system ,[object Object],[object Object],[object Object],[object Object]
Sensory Pathways ,[object Object],[object Object]
Sensory Reception and Transduction ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Transmission ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Perception ,[object Object],[object Object],[object Object]
Amplification and Adaptation ,[object Object],[object Object]
Hearing ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object]
Equilibrium ,[object Object],[object Object],[object Object]
Hearing and Equilibrium in Other Vertebrates ,[object Object],[object Object],[object Object]
Chapter 43 The Immune System
Overview: Reconnaissance, Recognition, and Response ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object]
Concept 43.2: In acquired immunity, lymphocyte receptors provide pathogen-specific recognition ,[object Object],[object Object]
[object Object],[object Object]
Acquired Immunity:  An Overview ,[object Object],[object Object]
Antigen Recognition by Lymphocytes ,[object Object],[object Object]
[object Object],[object Object]
The Antigen Receptors of B Cells and T Cells ,[object Object],[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object],Video: T Cell Receptors
[object Object],[object Object],[object Object]
The Role of the MHC ,[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
Cytotoxic T Cells: A Response to Infected Cells ,[object Object],[object Object],[object Object],[object Object],Animation: Cytotoxic T Cells
B Cells: A Response to Extracellular Pathogens ,[object Object],[object Object],[object Object]
Active and Passive Immunization ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]

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Power Points Sidesfor Test2

  • 1. Chapter 45 Hormones and the Endocrine System
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  • 14. Fig. 45-6-2 cAMP Second messenger Adenylyl cyclase G protein-coupled receptor ATP GTP G protein Epinephrine Inhibition of glycogen synthesis Promotion of glycogen breakdown Protein kinase A
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  • 16. Fig. 45-7-2 Hormone (estradiol) Hormone-receptor complex Plasma membrane Estradiol (estrogen) receptor DNA Vitellogenin mRNA for vitellogenin
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  • 18. Fig. 45-8-2 Glycogen deposits  receptor Vessel dilates. Epinephrine (a) Liver cell Epinephrine  receptor Glycogen breaks down and glucose is released. (b) Skeletal muscle blood vessel Same receptors but different intracellular proteins (not shown) Epinephrine  receptor Different receptors Epinephrine  receptor Vessel constricts. (c) Intestinal blood vessel
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  • 23. Fig. 45-12-5 Homeostasis: Blood glucose level (about 90 mg/100 mL) Glucagon STIMULUS: Blood glucose level falls. Alpha cells of pancreas release glucagon. Liver breaks down glycogen and releases glucose. Blood glucose level rises. STIMULUS: Blood glucose level rises. Beta cells of pancreas release insulin into the blood. Liver takes up glucose and stores it as glycogen. Blood glucose level declines. Body cells take up more glucose. Insulin
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  • 35. Fig. 45-21 Stress Adrenal gland Nerve cell Nerve signals Releasing hormone Hypothalamus Anterior pituitary Blood vessel ACTH Adrenal cortex Spinal cord Adrenal medulla Kidney (a) Short-term stress response (b) Long-term stress response Effects of epinephrine and norepinephrine: 2. Increased blood pressure 3. Increased breathing rate 4. Increased metabolic rate 1. Glycogen broken down to glucose; increased blood glucose 5. Change in blood flow patterns, leading to increased alertness and decreased digestive, excretory, and reproductive system activity Effects of mineralocorticoids: Effects of glucocorticoids: 1. Retention of sodium ions and water by kidneys 2. Increased blood volume and blood pressure 2. Possible suppression of immune system 1. Proteins and fats broken down and converted to glucose, leading to increased blood glucose
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  • 40. Chapter 46 Animal Reproduction Animal Reproduction Chapter 46
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  • 50. Fig. 46-12g Primordial germ cell Mitotic divisions Oogonium Mitotic divisions Primary oocyte (present at birth), arrested in prophase of meiosis I Completion of meiosis I and onset of meiosis II Secondary oocyte, arrested at metaphase of meiosis II First polar body Ovulation, sperm entry Completion of meiosis II Second polar body Fertilized egg 2 n 2 n n n n n In embryo
  • 51. Fig. 46-12c Primordial germ cell in embryo Mitotic divisions Spermatogonial stem cell Mitotic divisions Spermatogonium Mitotic divisions Primary spermatocyte Meiosis I Secondary spermatocyte Meiosis II Early spermatid Differentiation (Sertoli cells provide nutrients) Sperm 2 n 2 n 2 n n n n n n n n n n n
  • 52. Chapter 47 Animal Development
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  • 60. Fig. 47-6 (a) Fertilized egg (b) Four-cell stage (c) Early blastula (d) Later blastula
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  • 63. Fig. 47-8-6 Blastula (cross section) Blastocoel Animal pole 4-cell stage forming 2-cell stage forming Zygote 8-cell stage Vegetal pole 0.25 mm 0.25 mm
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  • 67. Fig. 47-10-4 Future ectoderm Key Future endoderm Future mesoderm SURFACE VIEW Animal pole Vegetal pole Early gastrula Blastopore Blastocoel Dorsal lip of blasto- pore CROSS SECTION Dorsal lip of blastopore Late gastrula Blastocoel shrinking Archenteron Blastocoel remnant Archenteron Blastopore Blastopore Yolk plug Ectoderm Mesoderm Endoderm
  • 68. Chapter 48 Neurons, Synapses, and Signaling
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  • 75. Fig. 48-4 Dendrites Stimulus Nucleus Cell body Axon hillock Presynaptic cell Axon Synaptic terminals Synapse Postsynaptic cell Neurotransmitter
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  • 83. Fig. 48-12 Axon Schwann cell Myelin sheath Nodes of Ranvier Node of Ranvier Schwann cell Nucleus of Schwann cell Layers of myelin Axon 0.1 µm
  • 84. Fig. 48-12a Axon Myelin sheath Schwann cell Nodes of Ranvier Schwann cell Nucleus of Schwann cell Node of Ranvier Layers of myelin Axon
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  • 88. Fig. 48-15 Voltage-gated Ca 2+ channel Ca 2+ 1 2 3 4 Synaptic cleft Ligand-gated ion channels Postsynaptic membrane Presynaptic membrane Synaptic vesicles containing neurotransmitter 5 6 K + Na +
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  • 98. Chapter 50 Sensory and Motor Mechanisms
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  • 112. Chapter 43 The Immune System
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Notes de l'éditeur

  1. Figure 45.6 Cell-surface hormone receptors trigger signal transduction
  2. Figure 45.7 Steroid hormone receptors directly regulate gene expression
  3. Figure 45.8 One hormone, different effects
  4. Figure 45.12 Maintenance of glucose homeostasis by insulin and glucagon
  5. Figure 45.21 Stress and the adrenal gland
  6. Figure 46.12 Human gametogenesis
  7. Figure 46.12 Human gametogenesis
  8. Figure 47.6 Cleavage in an echinoderm embryo
  9. Figure 47.8 Cleavage in a frog embryo
  10. Figure 47.10 Gastrulation in a frog embryo
  11. Figure 48.4 Neuron structure and organization For the Cell Biology Video Dendrites of a Neuron, go to Animation and Video Files.
  12. Figure 48.12 Schwann cells and the myelin sheath
  13. Figure 48.12 Schwann cells and the myelin sheath
  14. Figure 48.15 A chemical synapse