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Paget’s Disease of Bone   (Osteitis Deformans)   Hosain Bouallouch  Shen Zhou University 10 maart 2006
What is Paget’s disease? ,[object Object],[object Object],[object Object],[object Object]
Bone consists of: Osteoblasts: bone forming cells Osteoclasts: Bone breaking cells Osteocytes: present in the matrix Matrix: collagen, calcium, osteocalcin
Bone remodeling
2 forms of Paget’s disease ,[object Object],[object Object]
Bones commonly affected by Paget’s disease
Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Skull of patient with paget’s disease normal skull
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What causes Paget’s disease ,[object Object],[object Object]
How common is Paget’s disease ,[object Object],[object Object],[object Object],[object Object]
Epidemiology ,[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object]
Treatment  ,[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object]
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Paget’S Disease Of Bone