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THYROID OPHTHALMOPATHY
HARSHALI VIJAY MESTRI
2ND YEAR B-OPTOMETRY
ITM-IHS
THYROID EYE DISEASE
Seen in 25-50% of GRAVES DISEASE.
 GRAVES DISEASE also known as BASEDOW’S
DISEASE in an autoimmune disorder that usually
presents in 3rd to 4th decade of life, affect women
more than men .
THYROID EYE DISEASE (TED) may occur in the
absence of clinical and biochemical evidence of
thyroid dysfunction.
The occurrence of signs of graves disease in a
patient who is not clinically hyperthyroid is
referred to as euthyroid or ophthalmic graves
disease.
Eye disease may be the first presenting sign of
graves disease.
1. A patient has a graves disease the measure clinic
risk factor for developing TED is “SMOKING”.
2. Women are five times more likely to be affected
by TED than men.
3. Radioactive iodine used to treat Hyperthyrodism
can worsen TED.
4. Autoimmune disease association MYASTHENIA
GRAVIS , ADDISON DISEASE.
Thyroid ophthalmopathy involves an organ specific auto
immune reaction in which humoral agent IgG produces the
following changes:
INFLAMMATION OF EXTRAOCULAR
MUSCLES
INFLAMMATORY CELLULAR INFILTRATION
FAST/ IRREGULAR PULSE
WARM MOIST SKIN
FINE TREMOR
PALMER ERYTHEMA
HAIR LOSS
ORBITAL CELLULITIS : Onset of
proptosis is earlier & patient has other
evidence of infection. (Fever)
IOIOPATHIS ORBITAL
INFLAMMAATORY DISEASE : More
painful than thyroid eye disease .
NON SPECIFIC
Routine blood picture.
Haemoglobin .
WBC(total & differential count)
Blood sugar.
Cholesterol.
Urine examination.
SPECIFIC
FOR HYPERTHYROIDISM
Serum T3 & T4 level
Serum TSH level.
Thyroid  opthalmopathy
Thyroid  opthalmopathy
Thyroid  opthalmopathy
Thyroid  opthalmopathy

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Thyroid opthalmopathy

  • 1. THYROID OPHTHALMOPATHY HARSHALI VIJAY MESTRI 2ND YEAR B-OPTOMETRY ITM-IHS
  • 2. THYROID EYE DISEASE Seen in 25-50% of GRAVES DISEASE.  GRAVES DISEASE also known as BASEDOW’S DISEASE in an autoimmune disorder that usually presents in 3rd to 4th decade of life, affect women more than men .
  • 3. THYROID EYE DISEASE (TED) may occur in the absence of clinical and biochemical evidence of thyroid dysfunction. The occurrence of signs of graves disease in a patient who is not clinically hyperthyroid is referred to as euthyroid or ophthalmic graves disease. Eye disease may be the first presenting sign of graves disease.
  • 4. 1. A patient has a graves disease the measure clinic risk factor for developing TED is “SMOKING”. 2. Women are five times more likely to be affected by TED than men. 3. Radioactive iodine used to treat Hyperthyrodism can worsen TED. 4. Autoimmune disease association MYASTHENIA GRAVIS , ADDISON DISEASE.
  • 5. Thyroid ophthalmopathy involves an organ specific auto immune reaction in which humoral agent IgG produces the following changes: INFLAMMATION OF EXTRAOCULAR MUSCLES INFLAMMATORY CELLULAR INFILTRATION
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19. FAST/ IRREGULAR PULSE WARM MOIST SKIN FINE TREMOR PALMER ERYTHEMA HAIR LOSS
  • 20.
  • 21. ORBITAL CELLULITIS : Onset of proptosis is earlier & patient has other evidence of infection. (Fever) IOIOPATHIS ORBITAL INFLAMMAATORY DISEASE : More painful than thyroid eye disease .
  • 22. NON SPECIFIC Routine blood picture. Haemoglobin . WBC(total & differential count) Blood sugar. Cholesterol. Urine examination. SPECIFIC FOR HYPERTHYROIDISM Serum T3 & T4 level Serum TSH level.