Ist scientific possibilities_200911_web-2
- 1. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
MediSapiens Oy
Scientific possibilities of IST database
20. September 2011
- 2. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Stratify your patients with
thousands of others
Genomic signature for chromosomal instability
Hundredsofpatients
High
Medium
Low
Data from
your patiens?
Worst prognosis?
Resistant for therapy?
Best prognosis?
- 3. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
New therapy target for Ewing’s sarcoma?
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Novel breast cancer associated gene
Only three publications in PubMed
(none brca associated)
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High ectopic expression
in variety of cancers
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Key EMT regulator and
miRNA target in Brca
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Nearly unknown MMP related gene
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Known cell cycle player – new target
for Burkitt’s lymphoma therapy?
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Significant subsets of patients in multiple cancers
for a known phosphatase downstream of KRAS
- 10. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
We have a patent
pending algorithm*
that enables you to
compare your samples
with over 15 000 fully
annotated cancer
samples.
Here we see three
commonly used
melanoma cell lines,
and how their gene
expression matches
actual in vivo samples,
with regards to
melanoma specific
genes.
* Kilpinen et al. BioData Mining 2011, 4:5 Ojala et. al. Genome Medicine, In Press
Are you sure your model actually
models the cancer you study?
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IST Online
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