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Drug excretion lecture 10
1.
2.
3.
One Nephron of
the Kidney
4.
5.
6.
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8.
9.
10.
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12.
1.0 0.0 1.0
0.0 1.32 24.0 V.Weak 4.0 F 0.83 76.0 10.26 98.0 635.2 99.9 Weak 8.0 E 0.79 99.99 12.6 100.0 794.3 100.0 Strong 12.0 D BASES 1.0 0.3 0.99 0.02 0.99 0.0 V.Weak 10.0 C 1.25 97.0 0.115 66.6 0.04 3.0 Weak 6.0 B 1.26 100.0 0.8 99.99 0.001 99.7 Strong 2.0 A Acids Urine pH Valves 7.5 Cl R Urine pH Valves 7.5 % Ionized Urine pH Valves 6.3 Cl R Urine pH Valves 6.3 % Ionized Urine pH Valves 4.5 Cl R Urine pH Valaes 4.5 % Ionized Nature pK a Drugs
13.
14.
15.
16.
17.
18.
19.
Renal clearance (Cont.)
20.
21.
22.
23.
24.
25.
26.
Enterohepatic Recycling
27.
Cp versus Time
showing a Second Peak
28.
29.
30.
31.
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33.
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