Rapid prototyping is impacting medicine in several ways such as designing and developing medical devices, planning complex surgeries, surgical simulation, diagnosis, and manufacturing implants and tools. This document discusses the history and basic principles of rapid prototyping processes. It explores applications in orthopedics, maxillofacial surgery, and tissue engineering. Recent trends include using rapid prototyping to plan the separation of conjoined twins. The future of rapid prototyping in medicine depends on improvements in speed, cost, accuracy, biomaterials, and collaboration between medical professionals and engineers.