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International Journal of Technical Research and Applications e-ISSN: 2320-8163,
www.ijtra.com Volume 2, Issue 3 (May-June 2014), PP. 72-74 
72 | P a g e
INNOVATIVE TRENDS AND ASPECT OF
GREEN NANO-TECHNOLOGY DEVELOPMENT
CHALLENGES AND OPPORTUNITIES
Sahnoor Mohammad1
, Mahmood Alam2
1
Research Scholar, Department of Mechanical Engineering
2
Assistant Professor, Department of Mechanical Engineering
Integral University Lucknow India
Abstract— This paper represent the innovative trends
and aspect of green nanotechnology development
challenges and opportunities in the field of alternative
technology to assist in future developments in this field.
There are various innovative applications of green Nano-
technology in different- different fields like Energy,
Medicine and Drugs, Nano bio-technology, Nano devices,
Optical Engineering, Defence & Security, Bio
Engineering,Cosmetics,Nano Fabrics etc. Nanotechnology
improves the process of production and also improves the
quality of products. It works at the molecular level and
utilizes the more advanced concept, idea and research for
the development of different fields and production.
Index Terms— Green Nano Science, Carbon Nanotubes
(CNT), Single-walled Carbon Nano Tubes
(SWCNT),Multi-walled Carbon Nano Tubes
(MWCNT),Nano chemistry, Green engineering, Green
technology, TIM (Thermal Interface Materials).
I. INTRODUCTION.
Green engineering is the design, commercialisation
and use of processes and products that are feasible
and economical while:
Reducing the generation of pollution at the source,
minimizing the risk to human health and the
environment [1]. Nanotechnology improves the quality
of process which leads to the development of different
fields. A huge amount of research and development
activity has been devoted to Nano-scale related
technologies in recent years. The National Science
Foundation projects nanotechnology related products
will become a $1 trillion industry by 2015[2.]. The
concept of using Nano-fluids as a means of improving
coolant performance was proposed over a decade ago[3].
Reports of up to 100% increase in liquid thermal
conductivity with the addition of nanometre scale
particles motivated a large amount of scientific/technical
inquiry in the ensuing years
Figure 1.Application of nanotechnology
II. THE ROLE OF MECHANICAL ENGINEERING
IN NANOTECHNOLOGY
There is a very big role of mechanical engineering in
nanotechnology as mechanical have developed so many
useful instruments like Nano indenters and atomic force
microscopes for the mechanical testing, Nano scale
imaging and for precision measurement.
Mixtures of Nano- and micro- scale particles add
another dimension for controlling thermal, rheological
and mechanical properties [5].Of particular interest is the
use of carbon Nano-tubes for TIM (Thermal Interface
Materials) applications. The CNT is essentially a single
atomic layer of graphite (graphene) which is rolled up
onto itself. There are single- and multi-walled versions
of CNT which can exhibit thermal conductivity in excess
of 1000 Watts/meter ° Kelvin (for comparison, Cu =
400W/mK) and high tensile strength along the axis of
the tube. Applications to TIM have involved two basic
approaches:
Simple addition of CNT to the TIM matrix (grease,
gel,etc.)& Growth of vertically aligned CNT ‘carpets’ on
the heat sink or device package.
In the former approach, CNT loading is increased
until percolation of fibres provides a thermal path from
mating surfaces. In the latter growth method, the
individual CNT provide a direct high-conduction path
between surfaces [5,6].
International Journal of Technical Research and Applications e-ISSN: 2320-8163,
www.ijtra.com Volume 2, Issue 3 (May-June 2014), PP. 72-74 
73 | P a g e
Research has shown that optimal particle loading
achieves improved thermal conductivity and low
modulus (to accommodate thermal expansion mis match
of components) with a variety of materials and particles
hopes/sizes [7].
III. FUEL AND NANOTECHNOLOGY
Nanotechnology can address the shortage of fossil
fuels such as diesel and gasoline as it-
Making the production of fuels from low grade raw
materials economical, It increasing the mileage of
engines, and it also make the production of fuels from
normal raw materials more efficient [1].Since
nanotechnology also deals with the fuels and making the
production of fuel economical by utilizing the modern
concept, current works and development of green
nanotechnology.
Figure.2 Green gasoline by catalytic fast pyrolysis
The above figure shows that how low grade material
like woody biomass is being used for making green
gasoline by catalytic fast pyrolysis process which makes
the production of fuel economical.
IV. NANO-TECHNOLOGY APPLIED TO
SOLDERING SYSTEM
The industry has developed new solder alloys to
replace SnPb eutectic alloys, but the required processing
temperature must increase by about 35°C to
accommodate the alloy (tin silver copper family, SAC).
This increase in processing temperatures to about 235°C
to 245°C, results in additional unwanted thermal stress
on the electronic components being assembled as
compared to tin-lead assembly temperatures of about
210°C.Research is being conducted in the realm of
Nano-particle sized solder alloys. Metals undergo a
melting point depression when the particle size is
reduced to Nano-scale. Preliminary work by an iNEMI
Nano Solder Project Team [8] has worked towards
demonstrating that a reduction in melting temperature of
a solder alloy is feasible as a function of particle size.
V. ENVIRONMENTAL HEALTH & SAFETY
A critical feature of nanoparticles is their high
surface-area to-mass ratio. This property provides
additional sites for bonding or reaction with surrounding
material and results in unique characteristics such as
improved strength or heat resistance. Similarly, evidence
suggests that when in haled ,the large surface area of
insoluble nanoparticles creates the potential for greater
biological activity [9,10,11].Although dependent upon
their effective size in the body and other physio-
chemical characteristics, studies have also shown that
when nanoparticles are inhaled they may penetrate cell
swallowing direct access to the bloodstream and possibly
circumventing the blood-brain barrier or depositing in
other organs of the body [12,13].
Several studies have noted an increased risk of
biological responses from exposure to carbon Nano-
tubes [14, 15, 16, 17].
Both single-walled (SWCNT) and multi-walled
(MWCNT) carbon Nano-tubes are non-biodegradable
and resemble needle-like, carcinogenic asbestos fibres in
size, shape and cellular persistence. Until recently
several studies only suggested a potential link between
inhalation exposure to long MWCNTs and cancer, but
had not demonstrated that inhaled MWCNTs could
actually pass from the lung and into the surrounding
tissues [18, 19, 20].
Green Nanotechnology is an interdisciplinary rapidly
developing knowledge base at the interface of
agriculture, chemistry ,physics ,medical sciences
etc.[21].
The National Institute for Occupational Safety and
Health (NIOSH) researchers have reported new data
showing that MWCNTs can indeed migrate intact from
the lungs of mice and into the tissue surrounding the
lungs where asbestos induces a form of cancer known as
mesothelioma [22].Significant absorption of Nano-
material through the skin appears unlikely. Passive
diffusion appears to be the primary mechanism for
transport across the stratum corneum. The composition
of this outer layer of the skin creates an effective barrier
to dermal absorption of both chemicals. Although some
studies have indicated that penetration of particles in low
micron diameter size range is possible, penetration is
likely to be slow and not present an acute hazard [23].
VI. CHALLENGES AND OPPORTUNITY
Nanotechnology, as an emerging technology,
presents an important opportunity scientific and business
community. Nanotech is unlike some other sectors of the
chemical industry, where significant capital is already
invested in the form of large plants and established
supply chains in which production techniques are
technologically and culturally embedded. In fact, the
need to develop both new Nano products and their
equally novel production techniques presents an
important opportunity for innovators. In this case, there
International Journal of Technical Research and Applications e-ISSN: 2320-8163,
www.ijtra.com Volume 2, Issue 3 (May-June 2014), PP. 72-74 
74 | P a g e
is an unusual opportunity to use science, engineering and
policy knowledge to design novel products that are
benign as possible to human and environmental health.
Recognition of this opportunity has led to development
of “Green Nano science” concept [24,25].
VII. CONCLUSIONS
By the development and implementation of
nanotechnology, the automobiles industries growth will
be influenced and will use the innovative application of
the green nanotechnology which is suitable for human
health and environment .Metal nanoparticles are being
considered for potential use in catalytic converters since
the catalytic reactivity is significantly enhanced due to
the increased surface area of the metal. Coolants utilize
nanoparticles and Nano-powders to increase the
efficiency of heat transfer and potentially reduce the size
of the automotive cooling equipment. Some
manufacturers are currently using Nano-magnetic fluids
in shock absorbers to increase vibration control
efficiency. Nanotechnology will influence the auto
industry initially on a very small scale, but will certainly
be developed to deliver features, products and processes
that are almost unimaginable today.will be influenced
and will use the innovative application of the green
nanotechnology which is suitable for human health and
environment .Metal nanoparticles are being considered
for potential use in catalytic converters since the
catalytic reactivity is significantly enhanced due to the
increased surface area of the metal. Coolants utilize
nanoparticles and Nano-powders to increase the
efficiency of heat transfer and potentially reduce the size
of the automotive cooling equipment. Some
manufacturers are currently using Nano-magnetic fluids
in shock absorbers to increase vibration control
efficiency. Nanotechnology will influence the auto
industry initially on a very small scale, but will certainly
be developed to deliver features, products and processes
that are almost unimaginable today.
REFERENCES
[1] Mechanical Seminar Topics byKasarlashanthan/Ramesh
Gavva,December 4, 2011 posted in Mechanical Projects,
[2] http://1000projects.org/green-nanotechnology-in-automobiles-
mechanical-student-project.html
[3] J. of Nanoparticle Research, Kluwer Academic Publ., Vol.3, No.
5-6, pp. 353-360, 2001 (based on the presentation atthe
symposium Global Nanotechnology Networking,International
Union of Materials Meeting, August 28, 2001)
[4] Choi S.U.S., in “Developments and Applications of Non-
Newtonian Flows”, edited by Singer D.A., Wang H.P.,American
Society of Mechanical Engineers, Vol.231/MDVol.66, p.99
(New York, 1995).
[5] Keblinski P., Eastman J.A., Cahill D.G., Materials Today,p.36
(June 2005). [5.] Prasher R., Proceedings of the IEEE Vol.94,
No.8, p..1571(August 2006).
[6] HuX.J., Padilla A.A., Xu J., Fisher T.S., Goodson K.E., J.of
Heat Transfer, Vol.128, p.1109 (November 2006).
[7] Elliot J.A., Kelly A., Windle A.H., J. Mat.Sci.Ltrs. Vol.21,
p.1249 (2002).
[8] iNEMI Nano Solder Project Work, 2008 www.inemi.org
[9] Tran, C. L., et al (2000). Inhalation of poorly solubleparticles. II.
Influence of particle surface area oninflammation and
clearance. Inhal.Toxicol. 12, 1113-1126.
[10] Donaldson, K., and Tran, C. L. (2002). Inflammationcaused by
particles and fibers.Ihal.Toxicol. 14, 5-27.
[11] Duffin, R., et al (2002). The importance of surface areaand
specific reactivity in the acute
[12] Kreuter, J., et al (2002). Apolipoprotein-mediatedtransport of
nanoparticle-bound drugs across the blood-brainbarrier. J. Drug
Target. 10,317-325.
[13] Oberdorster, G., et al (2004). Translocation of inhaledultrafine
particles to the brain.Inhal.Toxicol. 16, 437-445.
[14] Shvedova, A.A., et al (2005). Unusual inflammatory
andfibrogenic pulmonary responses to single walled
carbonnano-tubes in mice. Am. J. Physiol.Lung Cell. Mol.
Physiol.,289 (5), L698
[15] Warheit, D.B., et al (2004). Comparative pulmonarytoxicity
assessment of single-wall carbon nano-tubes in rats.Toxicol.
Sci.77:117.
[16] Muller, J., et al (2005). Respiratory toxicity of multi-wallcarbon
nano-tubes.Toxicol.Appl.Pharmacol.207(3):221.
[17] Lademann, J., et al (2001). Investigation of follicularpenetration
of topically applied substances. Skin PharmacolAppl Skin
Physiol 14:17-22
[18] Poland, C.A., et al. (2008) Carbon nano-tubes introducedinto the
abdominal cavity of mice show asbestos-likepathogenicity in a
pilot study. Nat. Nanotechnol. 3:423-428
[19] Sakamoto, Y., et al. (2009) Induction of mesotheliomaby a
single intrascrotal administration of multi-wall carbonnano-
tubes in intact male Fischer 344 rats, J. Toxicol.Sci.34:65-76
[20] Takagi, A., et al. (2008). Induction of mesothelioma inp53+/-
mouse by intraperitoneal application of multi-wallcarbonnano-
tubes, J. Toxicol. Sci. 33:105-116
[21] Sam Higginbottom Institute of Agriculture, Technology &
Sciences (Formerly Allahabad Agricultural Institute) (Deemed -
to - be - University under Section 3 of UGC Act 1956)
Allahabad - 211 007, U.P., INDIA Date:August 6-7, 2013
Venue:Bogmallo Beach Resort Hotel, Bogmallo, Near Dabolim
Airport, Goa,INDIA Hosted By: In Partnership with University
of Missouri, USA
[22] Hubbs, A., et al. (2009). Persistent PulmonaryInflammation,
Airway Mucous Metaplasia and Migration ofMultiwalled
Carbon Nano-tubes from the Lung afterSubchronic Exposure,
Abstract 2193, The Toxicologist CD -An official Journal of the
Society of Toxicology, Volume108, Number S-1, March 2009
[23] [23.] Lademann, J., et al (2001). Investigation of
follicularpenetration oftopically applied substances. Skin
PharmacolAppl Skin Physiol 14:17-22
[24] [24.] L.C. McKenzie, J.E. Hutchison, Green nanoscience: An
integrated approach to greener products, processes, and
applications, ChimicaOggi• Chemistry Today. (2004) 25.
[25.] J.A. Dahl, B.L.S. Maddux, J.E. Hutchison, Toward greener
nanosynthesis, Chemical Reviews. 107 (2007) 2228-2269.

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INNOVATIVE TRENDS AND ASPECT OF GREEN NANO-TECHNOLOGY DEVELOPMENT CHALLENGES AND OPPORTUNITIES

  • 1. International Journal of Technical Research and Applications e-ISSN: 2320-8163, www.ijtra.com Volume 2, Issue 3 (May-June 2014), PP. 72-74  72 | P a g e INNOVATIVE TRENDS AND ASPECT OF GREEN NANO-TECHNOLOGY DEVELOPMENT CHALLENGES AND OPPORTUNITIES Sahnoor Mohammad1 , Mahmood Alam2 1 Research Scholar, Department of Mechanical Engineering 2 Assistant Professor, Department of Mechanical Engineering Integral University Lucknow India Abstract— This paper represent the innovative trends and aspect of green nanotechnology development challenges and opportunities in the field of alternative technology to assist in future developments in this field. There are various innovative applications of green Nano- technology in different- different fields like Energy, Medicine and Drugs, Nano bio-technology, Nano devices, Optical Engineering, Defence & Security, Bio Engineering,Cosmetics,Nano Fabrics etc. Nanotechnology improves the process of production and also improves the quality of products. It works at the molecular level and utilizes the more advanced concept, idea and research for the development of different fields and production. Index Terms— Green Nano Science, Carbon Nanotubes (CNT), Single-walled Carbon Nano Tubes (SWCNT),Multi-walled Carbon Nano Tubes (MWCNT),Nano chemistry, Green engineering, Green technology, TIM (Thermal Interface Materials). I. INTRODUCTION. Green engineering is the design, commercialisation and use of processes and products that are feasible and economical while: Reducing the generation of pollution at the source, minimizing the risk to human health and the environment [1]. Nanotechnology improves the quality of process which leads to the development of different fields. A huge amount of research and development activity has been devoted to Nano-scale related technologies in recent years. The National Science Foundation projects nanotechnology related products will become a $1 trillion industry by 2015[2.]. The concept of using Nano-fluids as a means of improving coolant performance was proposed over a decade ago[3]. Reports of up to 100% increase in liquid thermal conductivity with the addition of nanometre scale particles motivated a large amount of scientific/technical inquiry in the ensuing years Figure 1.Application of nanotechnology II. THE ROLE OF MECHANICAL ENGINEERING IN NANOTECHNOLOGY There is a very big role of mechanical engineering in nanotechnology as mechanical have developed so many useful instruments like Nano indenters and atomic force microscopes for the mechanical testing, Nano scale imaging and for precision measurement. Mixtures of Nano- and micro- scale particles add another dimension for controlling thermal, rheological and mechanical properties [5].Of particular interest is the use of carbon Nano-tubes for TIM (Thermal Interface Materials) applications. The CNT is essentially a single atomic layer of graphite (graphene) which is rolled up onto itself. There are single- and multi-walled versions of CNT which can exhibit thermal conductivity in excess of 1000 Watts/meter ° Kelvin (for comparison, Cu = 400W/mK) and high tensile strength along the axis of the tube. Applications to TIM have involved two basic approaches: Simple addition of CNT to the TIM matrix (grease, gel,etc.)& Growth of vertically aligned CNT ‘carpets’ on the heat sink or device package. In the former approach, CNT loading is increased until percolation of fibres provides a thermal path from mating surfaces. In the latter growth method, the individual CNT provide a direct high-conduction path between surfaces [5,6].
  • 2. International Journal of Technical Research and Applications e-ISSN: 2320-8163, www.ijtra.com Volume 2, Issue 3 (May-June 2014), PP. 72-74  73 | P a g e Research has shown that optimal particle loading achieves improved thermal conductivity and low modulus (to accommodate thermal expansion mis match of components) with a variety of materials and particles hopes/sizes [7]. III. FUEL AND NANOTECHNOLOGY Nanotechnology can address the shortage of fossil fuels such as diesel and gasoline as it- Making the production of fuels from low grade raw materials economical, It increasing the mileage of engines, and it also make the production of fuels from normal raw materials more efficient [1].Since nanotechnology also deals with the fuels and making the production of fuel economical by utilizing the modern concept, current works and development of green nanotechnology. Figure.2 Green gasoline by catalytic fast pyrolysis The above figure shows that how low grade material like woody biomass is being used for making green gasoline by catalytic fast pyrolysis process which makes the production of fuel economical. IV. NANO-TECHNOLOGY APPLIED TO SOLDERING SYSTEM The industry has developed new solder alloys to replace SnPb eutectic alloys, but the required processing temperature must increase by about 35°C to accommodate the alloy (tin silver copper family, SAC). This increase in processing temperatures to about 235°C to 245°C, results in additional unwanted thermal stress on the electronic components being assembled as compared to tin-lead assembly temperatures of about 210°C.Research is being conducted in the realm of Nano-particle sized solder alloys. Metals undergo a melting point depression when the particle size is reduced to Nano-scale. Preliminary work by an iNEMI Nano Solder Project Team [8] has worked towards demonstrating that a reduction in melting temperature of a solder alloy is feasible as a function of particle size. V. ENVIRONMENTAL HEALTH & SAFETY A critical feature of nanoparticles is their high surface-area to-mass ratio. This property provides additional sites for bonding or reaction with surrounding material and results in unique characteristics such as improved strength or heat resistance. Similarly, evidence suggests that when in haled ,the large surface area of insoluble nanoparticles creates the potential for greater biological activity [9,10,11].Although dependent upon their effective size in the body and other physio- chemical characteristics, studies have also shown that when nanoparticles are inhaled they may penetrate cell swallowing direct access to the bloodstream and possibly circumventing the blood-brain barrier or depositing in other organs of the body [12,13]. Several studies have noted an increased risk of biological responses from exposure to carbon Nano- tubes [14, 15, 16, 17]. Both single-walled (SWCNT) and multi-walled (MWCNT) carbon Nano-tubes are non-biodegradable and resemble needle-like, carcinogenic asbestos fibres in size, shape and cellular persistence. Until recently several studies only suggested a potential link between inhalation exposure to long MWCNTs and cancer, but had not demonstrated that inhaled MWCNTs could actually pass from the lung and into the surrounding tissues [18, 19, 20]. Green Nanotechnology is an interdisciplinary rapidly developing knowledge base at the interface of agriculture, chemistry ,physics ,medical sciences etc.[21]. The National Institute for Occupational Safety and Health (NIOSH) researchers have reported new data showing that MWCNTs can indeed migrate intact from the lungs of mice and into the tissue surrounding the lungs where asbestos induces a form of cancer known as mesothelioma [22].Significant absorption of Nano- material through the skin appears unlikely. Passive diffusion appears to be the primary mechanism for transport across the stratum corneum. The composition of this outer layer of the skin creates an effective barrier to dermal absorption of both chemicals. Although some studies have indicated that penetration of particles in low micron diameter size range is possible, penetration is likely to be slow and not present an acute hazard [23]. VI. CHALLENGES AND OPPORTUNITY Nanotechnology, as an emerging technology, presents an important opportunity scientific and business community. Nanotech is unlike some other sectors of the chemical industry, where significant capital is already invested in the form of large plants and established supply chains in which production techniques are technologically and culturally embedded. In fact, the need to develop both new Nano products and their equally novel production techniques presents an important opportunity for innovators. In this case, there
  • 3. International Journal of Technical Research and Applications e-ISSN: 2320-8163, www.ijtra.com Volume 2, Issue 3 (May-June 2014), PP. 72-74  74 | P a g e is an unusual opportunity to use science, engineering and policy knowledge to design novel products that are benign as possible to human and environmental health. Recognition of this opportunity has led to development of “Green Nano science” concept [24,25]. VII. CONCLUSIONS By the development and implementation of nanotechnology, the automobiles industries growth will be influenced and will use the innovative application of the green nanotechnology which is suitable for human health and environment .Metal nanoparticles are being considered for potential use in catalytic converters since the catalytic reactivity is significantly enhanced due to the increased surface area of the metal. Coolants utilize nanoparticles and Nano-powders to increase the efficiency of heat transfer and potentially reduce the size of the automotive cooling equipment. Some manufacturers are currently using Nano-magnetic fluids in shock absorbers to increase vibration control efficiency. Nanotechnology will influence the auto industry initially on a very small scale, but will certainly be developed to deliver features, products and processes that are almost unimaginable today.will be influenced and will use the innovative application of the green nanotechnology which is suitable for human health and environment .Metal nanoparticles are being considered for potential use in catalytic converters since the catalytic reactivity is significantly enhanced due to the increased surface area of the metal. Coolants utilize nanoparticles and Nano-powders to increase the efficiency of heat transfer and potentially reduce the size of the automotive cooling equipment. Some manufacturers are currently using Nano-magnetic fluids in shock absorbers to increase vibration control efficiency. Nanotechnology will influence the auto industry initially on a very small scale, but will certainly be developed to deliver features, products and processes that are almost unimaginable today. REFERENCES [1] Mechanical Seminar Topics byKasarlashanthan/Ramesh Gavva,December 4, 2011 posted in Mechanical Projects, [2] http://1000projects.org/green-nanotechnology-in-automobiles- mechanical-student-project.html [3] J. of Nanoparticle Research, Kluwer Academic Publ., Vol.3, No. 5-6, pp. 353-360, 2001 (based on the presentation atthe symposium Global Nanotechnology Networking,International Union of Materials Meeting, August 28, 2001) [4] Choi S.U.S., in “Developments and Applications of Non- Newtonian Flows”, edited by Singer D.A., Wang H.P.,American Society of Mechanical Engineers, Vol.231/MDVol.66, p.99 (New York, 1995). [5] Keblinski P., Eastman J.A., Cahill D.G., Materials Today,p.36 (June 2005). [5.] Prasher R., Proceedings of the IEEE Vol.94, No.8, p..1571(August 2006). [6] HuX.J., Padilla A.A., Xu J., Fisher T.S., Goodson K.E., J.of Heat Transfer, Vol.128, p.1109 (November 2006). [7] Elliot J.A., Kelly A., Windle A.H., J. Mat.Sci.Ltrs. Vol.21, p.1249 (2002). [8] iNEMI Nano Solder Project Work, 2008 www.inemi.org [9] Tran, C. L., et al (2000). Inhalation of poorly solubleparticles. II. Influence of particle surface area oninflammation and clearance. Inhal.Toxicol. 12, 1113-1126. [10] Donaldson, K., and Tran, C. L. (2002). Inflammationcaused by particles and fibers.Ihal.Toxicol. 14, 5-27. [11] Duffin, R., et al (2002). The importance of surface areaand specific reactivity in the acute [12] Kreuter, J., et al (2002). Apolipoprotein-mediatedtransport of nanoparticle-bound drugs across the blood-brainbarrier. J. Drug Target. 10,317-325. [13] Oberdorster, G., et al (2004). Translocation of inhaledultrafine particles to the brain.Inhal.Toxicol. 16, 437-445. [14] Shvedova, A.A., et al (2005). Unusual inflammatory andfibrogenic pulmonary responses to single walled carbonnano-tubes in mice. Am. J. Physiol.Lung Cell. Mol. Physiol.,289 (5), L698 [15] Warheit, D.B., et al (2004). Comparative pulmonarytoxicity assessment of single-wall carbon nano-tubes in rats.Toxicol. Sci.77:117. [16] Muller, J., et al (2005). Respiratory toxicity of multi-wallcarbon nano-tubes.Toxicol.Appl.Pharmacol.207(3):221. [17] Lademann, J., et al (2001). Investigation of follicularpenetration of topically applied substances. Skin PharmacolAppl Skin Physiol 14:17-22 [18] Poland, C.A., et al. (2008) Carbon nano-tubes introducedinto the abdominal cavity of mice show asbestos-likepathogenicity in a pilot study. Nat. Nanotechnol. 3:423-428 [19] Sakamoto, Y., et al. (2009) Induction of mesotheliomaby a single intrascrotal administration of multi-wall carbonnano- tubes in intact male Fischer 344 rats, J. Toxicol.Sci.34:65-76 [20] Takagi, A., et al. (2008). Induction of mesothelioma inp53+/- mouse by intraperitoneal application of multi-wallcarbonnano- tubes, J. Toxicol. Sci. 33:105-116 [21] Sam Higginbottom Institute of Agriculture, Technology & Sciences (Formerly Allahabad Agricultural Institute) (Deemed - to - be - University under Section 3 of UGC Act 1956) Allahabad - 211 007, U.P., INDIA Date:August 6-7, 2013 Venue:Bogmallo Beach Resort Hotel, Bogmallo, Near Dabolim Airport, Goa,INDIA Hosted By: In Partnership with University of Missouri, USA [22] Hubbs, A., et al. (2009). Persistent PulmonaryInflammation, Airway Mucous Metaplasia and Migration ofMultiwalled Carbon Nano-tubes from the Lung afterSubchronic Exposure, Abstract 2193, The Toxicologist CD -An official Journal of the Society of Toxicology, Volume108, Number S-1, March 2009 [23] [23.] Lademann, J., et al (2001). Investigation of follicularpenetration oftopically applied substances. Skin PharmacolAppl Skin Physiol 14:17-22 [24] [24.] L.C. McKenzie, J.E. Hutchison, Green nanoscience: An integrated approach to greener products, processes, and applications, ChimicaOggi• Chemistry Today. (2004) 25. [25.] J.A. Dahl, B.L.S. Maddux, J.E. Hutchison, Toward greener nanosynthesis, Chemical Reviews. 107 (2007) 2228-2269.