The document outlines 12 brain rules, including that exercise boosts brain power, the human brain evolved for survival, every brain is wired differently, attention is focused on engaging things, short-term memory requires repetition, long-term memory also benefits from repetition, quality sleep improves thinking, stress hinders learning, stimulating multiple senses enhances learning, vision is the most influential sense, male and female brains are biologically different, and humans have a drive to explore.