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Functional Medicine
THE 21ST CENTURY MEDICINE
Iwan HH - FORTIS GLOBAL PHARMA

1
Conventional Medicine involves a
system of diagnosis followed by an
algorithmic approach to a
treatment
Algorithm : “a finite set of well defined
instructions for accomplishing some
task which, given an initial state, will
result in a corresponding recognizable
end state.”

Iwan HH - FORTIS GLOBAL PHARMA

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Iwan HH - FORTIS GLOBAL PHARMA

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Iwan HH - FORTIS GLOBAL PHARMA

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Iwan HH - FORTIS GLOBAL PHARMA

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… is a science-based, healthcare approach
that assesses and treats underlying causes
of illness through individually tailored
therapies to restore health and improve
function

Iwan HH - FORTIS GLOBAL PHARMA

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… is a science-based system of personalized
medicine that focuses on the root causes of
chronic illness and the correction of these
underlying dysfunctions rather than treating
symptoms

Iwan HH - FORTIS GLOBAL PHARMA

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7 PRINCIPLES OF FUNCTIONAL MEDICINE

Scientific research
Physiology
Mechanisms
Interactions
Case Studies

1. Science based medicine that
connects the emerging research
base to clinical practise

Pharmaceutical
Placebo controlled –
double blind

Iwan HH - FORTIS GLOBAL PHARMA

8
7 PRINCIPLES OF FUNCTIONAL MEDICINE

Genetics
NOT your destiny.
Gene expression is
variable and able to be
manipulated.
Genes determine our
responses to specific
environmental factors

1. Science based medicine that
connects the emerging research
base to clinical practise
2. Biochemical individuality based
on genetic and environmental
uniqueness

Iwan HH - FORTIS GLOBAL PHARMA

9
7 PRINCIPLES OF FUNCTIONAL MEDICINE
Environment
Chemical, spiritual and
structural elements
combine to influence your
genetic expression.
Manipulation of your
environment can change
the expression of your
genes

1. Science based medicine that
connects the emerging research
base to clinical practise
2. Biochemical individuality based
on genetic and environmental
uniqueness

Iwan HH - FORTIS GLOBAL PHARMA

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STRESS

POLLUTION

ENVIRONMENT

EATING HABIT

ALCOHOL - SMOKING

OTHER
LIFESTYLES…

Iwan HH - FORTIS GLOBAL PHARMA

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STRESS

ENVIRONMENT

Environment
“… we have been able to identify modifiable
behavioral factors, including specific aspects
of diet, overweight, inactivity, and smoking
that account for over 70% of Stroke and Colon
Cancer, over 80% of CHD, and over 90% of
Adult-onset Diabetes”
Willet, WC Science, 2002:296. 659-97

Iwan HH - FORTIS GLOBAL PHARMA

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7 PRINCIPLES OF FUNCTIONAL MEDICINE
1. Science based medicine that
connects the emerging research
base to clinical practise
2. Biochemical individuality based
on genetic and environmental
uniqueness
3. Patient centered care rather than
disease focused

Iwan HH - FORTIS GLOBAL PHARMA

13
7 PRINCIPLES OF FUNCTIONAL MEDICINE
1. Science based medicine that
connects the emerging research
base to clinical practise
2. Biochemical individuality based
on genetic and environmental
uniqueness
3. Patient centered care rather than
disease focused
4. Dynamic balance of Internal and
External Factors
5. Weblike interconnetions of
physiological processes
Iwan HH - FORTIS GLOBAL PHARMA

14
Iwan HH - FORTIS GLOBAL PHARMA

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7 PRINCIPLES OF FUNCTIONAL MEDICINE
6. Promotion of organ reserve –
healthspan… not just lifespan

7. Health as a positive vitality – not
merely the absence of disease
Iwan HH - FORTIS GLOBAL PHARMA

16
ICEBERG ANALOGY

LIFESTYLE

GENETICS

ENVIRONMENT

The combinations of genetics, environmental inputs and lifestyle behaviors
are underlying factors that contribute to chronic symptoms and illness
Iwan HH - FORTIS GLOBAL PHARMA

17
ILLNESS

SYMPTOMS

LIFESTYLE

GENETICS

ENVIRONMENT

ICEBERG ANALOGY
The combinations of genetics, environmental inputs and lifestyle behaviors
are underlying factors that CONTRIBUTE TO CHRONIC SYMPTOMS AND ILLNESS
Iwan HH - FORTIS GLOBAL PHARMA

18
Weight Gain/Obesity
Constipation/Diarrhea
Hearburn/Indigestion
Bloating/Nausea/Gas
Memory Loss/Brain Fog
Dpression/Insomnia
Stiffness

High Blood Pressure
Increased Blood Sugar
Headaches/Dizziness
Systemic Inflammation
Fatigue/Weakness/Pain
Confusion/Anxiety
Swelling
SYMPTOMS

LIFESTYLE

GENETICS

ENVIRONMENT

ICEBERG ANALOGY
The combinations of genetics, environmental inputs and lifestyle behaviors
are underlying factors CAN MANIFEST AS VARIOUS SIGNS & SYMPTOMS
Iwan HH - FORTIS GLOBAL PHARMA

19
Autoimmune Diseases
Gastrointestinal Disease
Kidney & Bladder Disease
Musculoskeletal Disease
Mental Illness
Cancers

Heart & Lung Disease
Insulin Resistance & Diabetes
Gallbladder & Liver Disease
Neurological Disease
Thyroid Disease
Stroke

SYMPTOMS

LIFESTYLE

GENETICS

ENVIRONMENT

ICEBERG ANALOGY
The combinations of genetics, environmental inputs and lifestyle behaviors
are underlying factors THAT OVERTIME DEVELOP INTO CHRONIC DISEASE
Iwan HH - FORTIS GLOBAL PHARMA

20
CONVENTIONAL
MEDICINE DOCTORS
treat symptoms with
medications
SYMPTOMS

LIFESTYLE

FUNCTIONAL
MEDICINE DOCTORS
treat the underlying
causes

GENETICS

ENVIRONMENT

CONVENTIONAL MEDICINE DOCTORS typically prescribe mediations for symptoms –
whereas FUNCTIONAL MEDICINE DOCTORS addresses the underlying factors of
dysfunction and disease and then treat the whole Patient

Iwan HH - FORTIS GLOBAL PHARMA

21
o Hormonal and Neurotransmitter Imbalances
o Antioxidant imbalance and Mitochondrial
Function
o Immune and Inflammatory Imbalances
o Digestive, Absorptive, and Microbiological
Imbalances
o Nutritional Deficiencies and Imbalances
o Detoxification, biotransformation, and excretory
Imbalances
o Structural and Functional Imbalances
Iwan HH - FORTIS GLOBAL PHARMA

22
• Medical and Nutritional History
• Physical Examination
• Musculoskeletal and Structural
Assessment
• Body Composition Assessment
• Cardiovascular and Fitness
Assessment
• Diagnostic Lab Tests
• Customized Wellness Programs

Iwan HH - FORTIS GLOBAL PHARMA

Diagnostic Lab Tests
• Urinalysis
• Blood Chemistry
• Micronutrient Testing
(Vitamin Deficiencies)
• Hormone Testing (Saliva,
Blood, or Urine)
• Stool Analysis (Digestion,
Bacteria, Inflammation)
• Toxin and Heavy Metal
Screening
• Allergies and Food
Sensitivities
• Oxidative Stress
• Bone Loss

23
• Medical and Nutritional History
• Physical Examination
• Musculoskeletal and Structural
Assessment
• Body Composition Assessment
• Cardiovascular and Fitness
Assessment
• Diagnostic Lab Tests
• Customized Wellness Programs

Iwan HH - FORTIS GLOBAL PHARMA

Wellness Programs
Based on the Patient’s history,
examination and laboratory
test findings, a customized
wellness program is prescribed
designed to correct the
underlying dysfuctions using
Dietary and Nutraceutical
Protocols
The Wellness Program is the
foundation to which other
treatments can be added as
needed such as detoxification,
physical medicine, chiropractic
care, acupuncture, exercise,
24
stress management and more…
“The doctor of the future will give no medicine,
but will interest his patients in the care of the
human frame, in a proper diet, and in the cause
and prevention of disease.” Thomas Edison

Iwan HH - FORTIS GLOBAL PHARMA

25

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Functional medicine

  • 1. Functional Medicine THE 21ST CENTURY MEDICINE Iwan HH - FORTIS GLOBAL PHARMA 1
  • 2. Conventional Medicine involves a system of diagnosis followed by an algorithmic approach to a treatment Algorithm : “a finite set of well defined instructions for accomplishing some task which, given an initial state, will result in a corresponding recognizable end state.” Iwan HH - FORTIS GLOBAL PHARMA 2
  • 3. Iwan HH - FORTIS GLOBAL PHARMA 3
  • 4. Iwan HH - FORTIS GLOBAL PHARMA 4
  • 5. Iwan HH - FORTIS GLOBAL PHARMA 5
  • 6. … is a science-based, healthcare approach that assesses and treats underlying causes of illness through individually tailored therapies to restore health and improve function Iwan HH - FORTIS GLOBAL PHARMA 6
  • 7. … is a science-based system of personalized medicine that focuses on the root causes of chronic illness and the correction of these underlying dysfunctions rather than treating symptoms Iwan HH - FORTIS GLOBAL PHARMA 7
  • 8. 7 PRINCIPLES OF FUNCTIONAL MEDICINE Scientific research Physiology Mechanisms Interactions Case Studies 1. Science based medicine that connects the emerging research base to clinical practise Pharmaceutical Placebo controlled – double blind Iwan HH - FORTIS GLOBAL PHARMA 8
  • 9. 7 PRINCIPLES OF FUNCTIONAL MEDICINE Genetics NOT your destiny. Gene expression is variable and able to be manipulated. Genes determine our responses to specific environmental factors 1. Science based medicine that connects the emerging research base to clinical practise 2. Biochemical individuality based on genetic and environmental uniqueness Iwan HH - FORTIS GLOBAL PHARMA 9
  • 10. 7 PRINCIPLES OF FUNCTIONAL MEDICINE Environment Chemical, spiritual and structural elements combine to influence your genetic expression. Manipulation of your environment can change the expression of your genes 1. Science based medicine that connects the emerging research base to clinical practise 2. Biochemical individuality based on genetic and environmental uniqueness Iwan HH - FORTIS GLOBAL PHARMA 10
  • 11. STRESS POLLUTION ENVIRONMENT EATING HABIT ALCOHOL - SMOKING OTHER LIFESTYLES… Iwan HH - FORTIS GLOBAL PHARMA 11
  • 12. STRESS ENVIRONMENT Environment “… we have been able to identify modifiable behavioral factors, including specific aspects of diet, overweight, inactivity, and smoking that account for over 70% of Stroke and Colon Cancer, over 80% of CHD, and over 90% of Adult-onset Diabetes” Willet, WC Science, 2002:296. 659-97 Iwan HH - FORTIS GLOBAL PHARMA 12
  • 13. 7 PRINCIPLES OF FUNCTIONAL MEDICINE 1. Science based medicine that connects the emerging research base to clinical practise 2. Biochemical individuality based on genetic and environmental uniqueness 3. Patient centered care rather than disease focused Iwan HH - FORTIS GLOBAL PHARMA 13
  • 14. 7 PRINCIPLES OF FUNCTIONAL MEDICINE 1. Science based medicine that connects the emerging research base to clinical practise 2. Biochemical individuality based on genetic and environmental uniqueness 3. Patient centered care rather than disease focused 4. Dynamic balance of Internal and External Factors 5. Weblike interconnetions of physiological processes Iwan HH - FORTIS GLOBAL PHARMA 14
  • 15. Iwan HH - FORTIS GLOBAL PHARMA 15
  • 16. 7 PRINCIPLES OF FUNCTIONAL MEDICINE 6. Promotion of organ reserve – healthspan… not just lifespan 7. Health as a positive vitality – not merely the absence of disease Iwan HH - FORTIS GLOBAL PHARMA 16
  • 17. ICEBERG ANALOGY LIFESTYLE GENETICS ENVIRONMENT The combinations of genetics, environmental inputs and lifestyle behaviors are underlying factors that contribute to chronic symptoms and illness Iwan HH - FORTIS GLOBAL PHARMA 17
  • 18. ILLNESS SYMPTOMS LIFESTYLE GENETICS ENVIRONMENT ICEBERG ANALOGY The combinations of genetics, environmental inputs and lifestyle behaviors are underlying factors that CONTRIBUTE TO CHRONIC SYMPTOMS AND ILLNESS Iwan HH - FORTIS GLOBAL PHARMA 18
  • 19. Weight Gain/Obesity Constipation/Diarrhea Hearburn/Indigestion Bloating/Nausea/Gas Memory Loss/Brain Fog Dpression/Insomnia Stiffness High Blood Pressure Increased Blood Sugar Headaches/Dizziness Systemic Inflammation Fatigue/Weakness/Pain Confusion/Anxiety Swelling SYMPTOMS LIFESTYLE GENETICS ENVIRONMENT ICEBERG ANALOGY The combinations of genetics, environmental inputs and lifestyle behaviors are underlying factors CAN MANIFEST AS VARIOUS SIGNS & SYMPTOMS Iwan HH - FORTIS GLOBAL PHARMA 19
  • 20. Autoimmune Diseases Gastrointestinal Disease Kidney & Bladder Disease Musculoskeletal Disease Mental Illness Cancers Heart & Lung Disease Insulin Resistance & Diabetes Gallbladder & Liver Disease Neurological Disease Thyroid Disease Stroke SYMPTOMS LIFESTYLE GENETICS ENVIRONMENT ICEBERG ANALOGY The combinations of genetics, environmental inputs and lifestyle behaviors are underlying factors THAT OVERTIME DEVELOP INTO CHRONIC DISEASE Iwan HH - FORTIS GLOBAL PHARMA 20
  • 21. CONVENTIONAL MEDICINE DOCTORS treat symptoms with medications SYMPTOMS LIFESTYLE FUNCTIONAL MEDICINE DOCTORS treat the underlying causes GENETICS ENVIRONMENT CONVENTIONAL MEDICINE DOCTORS typically prescribe mediations for symptoms – whereas FUNCTIONAL MEDICINE DOCTORS addresses the underlying factors of dysfunction and disease and then treat the whole Patient Iwan HH - FORTIS GLOBAL PHARMA 21
  • 22. o Hormonal and Neurotransmitter Imbalances o Antioxidant imbalance and Mitochondrial Function o Immune and Inflammatory Imbalances o Digestive, Absorptive, and Microbiological Imbalances o Nutritional Deficiencies and Imbalances o Detoxification, biotransformation, and excretory Imbalances o Structural and Functional Imbalances Iwan HH - FORTIS GLOBAL PHARMA 22
  • 23. • Medical and Nutritional History • Physical Examination • Musculoskeletal and Structural Assessment • Body Composition Assessment • Cardiovascular and Fitness Assessment • Diagnostic Lab Tests • Customized Wellness Programs Iwan HH - FORTIS GLOBAL PHARMA Diagnostic Lab Tests • Urinalysis • Blood Chemistry • Micronutrient Testing (Vitamin Deficiencies) • Hormone Testing (Saliva, Blood, or Urine) • Stool Analysis (Digestion, Bacteria, Inflammation) • Toxin and Heavy Metal Screening • Allergies and Food Sensitivities • Oxidative Stress • Bone Loss 23
  • 24. • Medical and Nutritional History • Physical Examination • Musculoskeletal and Structural Assessment • Body Composition Assessment • Cardiovascular and Fitness Assessment • Diagnostic Lab Tests • Customized Wellness Programs Iwan HH - FORTIS GLOBAL PHARMA Wellness Programs Based on the Patient’s history, examination and laboratory test findings, a customized wellness program is prescribed designed to correct the underlying dysfuctions using Dietary and Nutraceutical Protocols The Wellness Program is the foundation to which other treatments can be added as needed such as detoxification, physical medicine, chiropractic care, acupuncture, exercise, 24 stress management and more…
  • 25. “The doctor of the future will give no medicine, but will interest his patients in the care of the human frame, in a proper diet, and in the cause and prevention of disease.” Thomas Edison Iwan HH - FORTIS GLOBAL PHARMA 25