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Regional Program of Action and 
Demonstration of Sustainable Alternatives to 
DDT for Malaria Vector Control in Mexico 
and Central America 
Third Biennial International Waters 
Conference 
Salvador, Bahia, Brazil. 
20-25 June 2005
Focal Areas 
This Project conforms with the Contaminant-based 
Operational Program No. 10 and will help 
demonstrate ways of overcoming barriers to the 
adoption of best practices that limit contamination 
of the international waters environment. 
The proposed activities are also consistent with 
several provisions with the adopted Stockholm 
Convention on POPs. DDT is one of the POPs in the 
Stockholm Convention.
M While Maallaarriiaa iiss IInnccrreeaassiinngg iinn TThhee AAmmeerriiccaass 
PP.. VViivvaaxx yy PP.. FFaallcciippaarruumm 
11995599 -- 11999999 
PAHO/WHO 
Year 
Number of cases (thousand)
Financing iinn MMaallaarriiaa CCaammppaaiiggnnss 
iinn TThhee AAmmeerriiccaass iiss DDeeccrreeaassiinngg 
300 
250 
US$ millions Year 
200 
150 
100 
50 
0 
58 60 62 64 66 58 70 72 74 76 78 80 82 84 86 88 90 92 94 96 98 
PAHO/WHO 
11995588 -- 11999999
DDT in the Environment, Including 
International Waters and Human 
Bodies.
Facts on the Course of DDT 
• DDT was Used for Public Health 
Malaria and other Vector Born Disease 
Control. 
• Central America and Mexico Stopped 
DDT Use in the 1990’s and 2000. 
• DDT is Still found in the Environment 
and Human Bodies.
Dispersion of DDT in Mexico 
Levels of DDT found on 
sediments in the Lagoons 
of Zempoala, Morelos 
and its comparison with 
DDT used for malaria 
control in Mexico 
Decades 
DDT applied (t) 
Year 
DDT used in Mexico
Impact in Biota 
Concentration of DDT (ng/g) in species of the food chain in 
“La Cigüeña”, Chiapas (2002) 
Birds = 232.50 
Fish = 24.08 Crabs = 23.84 
Sediment = 138.37
Impact in the Environment 
Total DDT (mg/kg) in superficial soil in malaria communities 
in 2002 
La Ventanilla 
La Cigüeña 
Lacandona 
45,000 
40,000 
35,000 
30,000 
25,000 
20,000 
15,000 
10,000 
5,000 
0 
Total DDT 
Average (μg/kg) 
Total DDT interior 
Total DDT exterior 
Ventanilla Cigüeña Lacandona
Impact in Humans 
DDT blood concentration in children (mg/L) 
80 
70 
60 
50 
40 
30 
20 
10 
0 
DDT in blood in children "La Cigüeña", Chiapas 
2000 2001 2002 2003 2004 
Years 
DDD (μg/L) 
DDE (μg/L) 
DDT (μg/L) 
Mean concentration (mg/L)
Impact in Humans 
DDT, DDE and DDEms levels in breast milk of 30 Mexican 
mothers (ng/g lipid) 
Substance Sweden 
1992 
Mexico 
2004 
DDT 22 366 
DDE 227 1683 
DDEms 0.4 3.4
UNEP/ GEF/ PAHO Project to Demonstrate 
DDT Alternatives for Malaria Control. 
Participating 
countries 
Belize, Costa Rica, El Salvador, Guatemala, 
Honduras, Mexico, Nicaragua, Panama 
Implementing 
agency 
•United Nations Environment Programme 
Executing 
agency 
•Pan American Health Organization (PAHO) 
•National Governments 
Funding 
Partners 
•Global Environment Facility 
•National Governments 
•PAHO 
•CEC 
Total 
7.165 
5.865 
0.654 
0.200 
US$ 13.884 
Duration Three years: August 2003- July 2006
Overall Objective 
• To demonstrate that methods for malaria vector 
control without DDT or other persistent pesticides 
are replicable, cost-effective and sustainable thus 
preventing the reintroduction of DDT in the Region. 
Components 
• Elimination of DDT stockpiles 
• Implementation of demonstration projects on alternatives 
to DDT for Malaria Control and dissemination 
• Strengthening of national institutional capacity to control 
malaria without DDT 
• Coordination and management
Inventory of DDT and Other POPs 
Country DDT 
Other 
POPs 
Belize 13.000 0.008 
Costa Rica 8.621 0.122 
El Salvador 4.672 46.252 
Guatemala 15.058 
Honduras 3.539 12.490 
Mexico 87.000 
Nicaragua 0.003 5.647 
Panama 4.545 
Total 136.438 64.519
Implementation Strategy 
• To integrate epidemiology with socio-economic 
issues, entomology, public health, environment, 
water and provision of health care. 
– Epidemiological stratification with risk approach 
– Elimination of the persistent parasite 
– Ecological larvae control with social participation 
– Control of the adult mosquito with inexpensive 
techniques and low environmental impact 
– Sustained sanitation educational program aimed at the 
community
MMooddeell ffoorr MMaallaarriiaa CCoonnttrrooll 
1. Community participation can provide mosquito 
control management by regulating or modifying the 
breeding sites in water bodies and areas surrounding 
houses. 
2. Hygiene seems to play a great roll in malaria 
transmission. Good sanitation and familiar hygiene 
can reduce mosquito attraction. 
3. If malaria concentrates in only a few households, 
then suitable drug treatment can reduce infection 
sources and the risk for the community.
AAqquuaattiicc HHaabbiittaatt ooff LLaarrvvaall SSttaaggeess 
The breeding sites are influenced by the presence of water in 
streams and rivers. 
The breeding sites are characterized by the presence of low 
flux of streams and green algae.
Technical Manual on 
Demonstration Activities 
Guide for the 
implementation and 
demonstration of 
sustainable alternatives 
for the integrated 
control of malaria in 
Mexico and Central 
America
Collection, Discussion and 
Dissemination of Information 
http://shp.paho.org/sde/ddtgef/default.aspx
Geographic Information System Models used 
in the Project 
Tropical rainforest distribution (red) 
CONABIO map Mex. 1999 and CIESIN 
satellite image, 1995 
Areas below 800 meters above average sea level. 
Digital Elevation Model (DEM), 
USGS, 2001. 
API by first sub-national level in Mesoamerica 
(Central America Basic Indicators 2001) and 
Mexico Rates x 1000 inhabitants by second 
administrative level (SUAVE, Mex, 2001) 
The SIGEpi perspective has the purpose of standardizing, integrating, compiling and facilitate the 
interchange of digital cartographic infrastructure ( data, methods and software) as a foundation for 
analyzing geographically the data about malaria vector control and DDT residuals.
Costa Rica’ s GIS Local Scale 
Observation Level for Malaria 
Control 
Mosquito breeding sites 
and surrounding positive 
houses to malaria 
Progress in the 
GPS dwellings 
survey in localities 
along the border 
corridor between 
Costa Rica and 
Panama 
Paper map 
The same map in vector and raster 
digital format in SIGEpi 
GPS demonstration 
Panama 
Costa Rica
From Sketch to Digital Maps in 
Panama Showing Malaria 
Houses (red houses) 
Calculating the number of 
preventive treatments in 
the 200 meters 
surroundings
Organizational Chart 
Steering Committee 
8 Ministers of Health 
PAHO 
UNEP 
CEC 
CCAD 
Observers: World Bank, UNDP, 
NGOs, other cooperation agencies 
Regional Operational 
Committee 
1 Regional Coordinator 
8 Focal Points (Health) 
8 National Coordinators 
Representatives from NGOs and 
the Civil Society 
National Committee 
National Focal Point (Health) 
National Coordinator 
Environment Representative 
Agriculture Representative 
Customs or Immigration Representative 
9 Working Groups 
Demonstration Projects 
National Coordinator 
Focal Point 
Environment Representative 
Agriculture representative 
UNEP/GEF 
Implementing/Donor Agencies 
PAHO 
Executing Agency 
CEC 
Cooperation Agency 
Advisory Committee 
Universities, Research Institutions 
Civil Society, Organizations and 
NGOs with activities related to the 
project 
Advisory Committee 
One representative from each 
governmental unit 
Representatives from NGOs and the 
Civil Society

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Regional Program of Action and Demonstration of Sustainable Alternatives to DDT for Malaria Vector Control in Mexico and Central America

  • 1. Regional Program of Action and Demonstration of Sustainable Alternatives to DDT for Malaria Vector Control in Mexico and Central America Third Biennial International Waters Conference Salvador, Bahia, Brazil. 20-25 June 2005
  • 2. Focal Areas This Project conforms with the Contaminant-based Operational Program No. 10 and will help demonstrate ways of overcoming barriers to the adoption of best practices that limit contamination of the international waters environment. The proposed activities are also consistent with several provisions with the adopted Stockholm Convention on POPs. DDT is one of the POPs in the Stockholm Convention.
  • 3. M While Maallaarriiaa iiss IInnccrreeaassiinngg iinn TThhee AAmmeerriiccaass PP.. VViivvaaxx yy PP.. FFaallcciippaarruumm 11995599 -- 11999999 PAHO/WHO Year Number of cases (thousand)
  • 4. Financing iinn MMaallaarriiaa CCaammppaaiiggnnss iinn TThhee AAmmeerriiccaass iiss DDeeccrreeaassiinngg 300 250 US$ millions Year 200 150 100 50 0 58 60 62 64 66 58 70 72 74 76 78 80 82 84 86 88 90 92 94 96 98 PAHO/WHO 11995588 -- 11999999
  • 5. DDT in the Environment, Including International Waters and Human Bodies.
  • 6. Facts on the Course of DDT • DDT was Used for Public Health Malaria and other Vector Born Disease Control. • Central America and Mexico Stopped DDT Use in the 1990’s and 2000. • DDT is Still found in the Environment and Human Bodies.
  • 7. Dispersion of DDT in Mexico Levels of DDT found on sediments in the Lagoons of Zempoala, Morelos and its comparison with DDT used for malaria control in Mexico Decades DDT applied (t) Year DDT used in Mexico
  • 8. Impact in Biota Concentration of DDT (ng/g) in species of the food chain in “La Cigüeña”, Chiapas (2002) Birds = 232.50 Fish = 24.08 Crabs = 23.84 Sediment = 138.37
  • 9. Impact in the Environment Total DDT (mg/kg) in superficial soil in malaria communities in 2002 La Ventanilla La Cigüeña Lacandona 45,000 40,000 35,000 30,000 25,000 20,000 15,000 10,000 5,000 0 Total DDT Average (μg/kg) Total DDT interior Total DDT exterior Ventanilla Cigüeña Lacandona
  • 10. Impact in Humans DDT blood concentration in children (mg/L) 80 70 60 50 40 30 20 10 0 DDT in blood in children "La Cigüeña", Chiapas 2000 2001 2002 2003 2004 Years DDD (μg/L) DDE (μg/L) DDT (μg/L) Mean concentration (mg/L)
  • 11. Impact in Humans DDT, DDE and DDEms levels in breast milk of 30 Mexican mothers (ng/g lipid) Substance Sweden 1992 Mexico 2004 DDT 22 366 DDE 227 1683 DDEms 0.4 3.4
  • 12. UNEP/ GEF/ PAHO Project to Demonstrate DDT Alternatives for Malaria Control. Participating countries Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama Implementing agency •United Nations Environment Programme Executing agency •Pan American Health Organization (PAHO) •National Governments Funding Partners •Global Environment Facility •National Governments •PAHO •CEC Total 7.165 5.865 0.654 0.200 US$ 13.884 Duration Three years: August 2003- July 2006
  • 13. Overall Objective • To demonstrate that methods for malaria vector control without DDT or other persistent pesticides are replicable, cost-effective and sustainable thus preventing the reintroduction of DDT in the Region. Components • Elimination of DDT stockpiles • Implementation of demonstration projects on alternatives to DDT for Malaria Control and dissemination • Strengthening of national institutional capacity to control malaria without DDT • Coordination and management
  • 14. Inventory of DDT and Other POPs Country DDT Other POPs Belize 13.000 0.008 Costa Rica 8.621 0.122 El Salvador 4.672 46.252 Guatemala 15.058 Honduras 3.539 12.490 Mexico 87.000 Nicaragua 0.003 5.647 Panama 4.545 Total 136.438 64.519
  • 15. Implementation Strategy • To integrate epidemiology with socio-economic issues, entomology, public health, environment, water and provision of health care. – Epidemiological stratification with risk approach – Elimination of the persistent parasite – Ecological larvae control with social participation – Control of the adult mosquito with inexpensive techniques and low environmental impact – Sustained sanitation educational program aimed at the community
  • 16. MMooddeell ffoorr MMaallaarriiaa CCoonnttrrooll 1. Community participation can provide mosquito control management by regulating or modifying the breeding sites in water bodies and areas surrounding houses. 2. Hygiene seems to play a great roll in malaria transmission. Good sanitation and familiar hygiene can reduce mosquito attraction. 3. If malaria concentrates in only a few households, then suitable drug treatment can reduce infection sources and the risk for the community.
  • 17. AAqquuaattiicc HHaabbiittaatt ooff LLaarrvvaall SSttaaggeess The breeding sites are influenced by the presence of water in streams and rivers. The breeding sites are characterized by the presence of low flux of streams and green algae.
  • 18.
  • 19. Technical Manual on Demonstration Activities Guide for the implementation and demonstration of sustainable alternatives for the integrated control of malaria in Mexico and Central America
  • 20. Collection, Discussion and Dissemination of Information http://shp.paho.org/sde/ddtgef/default.aspx
  • 21. Geographic Information System Models used in the Project Tropical rainforest distribution (red) CONABIO map Mex. 1999 and CIESIN satellite image, 1995 Areas below 800 meters above average sea level. Digital Elevation Model (DEM), USGS, 2001. API by first sub-national level in Mesoamerica (Central America Basic Indicators 2001) and Mexico Rates x 1000 inhabitants by second administrative level (SUAVE, Mex, 2001) The SIGEpi perspective has the purpose of standardizing, integrating, compiling and facilitate the interchange of digital cartographic infrastructure ( data, methods and software) as a foundation for analyzing geographically the data about malaria vector control and DDT residuals.
  • 22. Costa Rica’ s GIS Local Scale Observation Level for Malaria Control Mosquito breeding sites and surrounding positive houses to malaria Progress in the GPS dwellings survey in localities along the border corridor between Costa Rica and Panama Paper map The same map in vector and raster digital format in SIGEpi GPS demonstration Panama Costa Rica
  • 23. From Sketch to Digital Maps in Panama Showing Malaria Houses (red houses) Calculating the number of preventive treatments in the 200 meters surroundings
  • 24. Organizational Chart Steering Committee 8 Ministers of Health PAHO UNEP CEC CCAD Observers: World Bank, UNDP, NGOs, other cooperation agencies Regional Operational Committee 1 Regional Coordinator 8 Focal Points (Health) 8 National Coordinators Representatives from NGOs and the Civil Society National Committee National Focal Point (Health) National Coordinator Environment Representative Agriculture Representative Customs or Immigration Representative 9 Working Groups Demonstration Projects National Coordinator Focal Point Environment Representative Agriculture representative UNEP/GEF Implementing/Donor Agencies PAHO Executing Agency CEC Cooperation Agency Advisory Committee Universities, Research Institutions Civil Society, Organizations and NGOs with activities related to the project Advisory Committee One representative from each governmental unit Representatives from NGOs and the Civil Society

Notes de l'éditeur

  1. Thank you mister chairman. I am Emilio Ramirez Pinto, regional coordinator of the Regional Program of Action and Demonstration of Sustainable Alternatives to DDT for Malaria Vector Control in Mexico and Central America, and on behalf of all the professionals involved in this project I would like to share with you in the following minutes the progresses achieved so far in this project. DDT was used in the region for much of the second half of the twentieth century, raising the concern on the effects to human and environmental exposure in the areas sprayed with DDT. However, 35 percent of the Mexican and Central American population lives in malaria endemic areas or are at risk of developing this disease. But successful experiences developed in Mexico and Central America during the last years has showed that it is possible to control the malaria vector without using DDT. Next slide please.
  2. This concern shared by the governments of Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico Nicaragua and Panama prompted the implementation of this three-year project of regional scope, implemented by the United Nations Environment Programme, executed by the Pan American Health Organization and the national governments and funded by the Global Environment Fund, cash and in kind cooperation from the participating governments, PAHO in kind input and the contribution from the Commission for Environmental Cooperation of North America. Next slide please.
  3. This project seeks to demonstrate that the methods used to control malaria without DDT or other persistent organic pollutants are replicable, effective and sustainable, thus preventing the reintroduction of DDT in the region. There are four different groups of action necessary to address the countries’ needs to lower their vulnerability to using DDT for malaria control. First, the development of nine demonstration projects under specific environmental and socio-economic conditions, with detailed monitoring and evaluation with the participation of environment and health national services and the local communities. Second, to improve the analytical capacity of the national laboratories for the evaluation of exposure to plaguicides; to strengthen the regional and national malaria surveillance systems; to strengthen the institutions providing care for malaria and to implement the geographic information system. Third, update of the national inventories of DDT and other POPs, repackage, shipment and final disposal according to the Stockholm and Basel Conventions and raise political willingness to prevent recurrence of DDT stockpiles. And fourth, Coordination and management. Next slide please.
  4. The standardized form for the inventory of DDT and other POPs was made through and agreement with the Regional Institute of Toxicology in Costa Rica and seven countries have concluded data collection, which include information on location, type of pesticide, storage conditions and others. A total of 136.438 metric tons of DDT were found in the region (data from Mexico is preliminary and its based on the PDF-B assessment). Also 64.519 metric tons of other persisntes pollutants were found in the region. Thank you for your attention.
  5. The strategy for the successful implementation of the project is to integrate epidemiology with social sciences, entomology, public health, environment, health care services and other scientific fields of a model validated by Mexico and enriched by the other countries. The model is based on the epidemiological stratification with a risk approach; the elimination of the persistent parasite; ecological larval control with social participation; control of the adult anopheles with inexpensive techniques and with the lowest impact to the ecosystem; and a sustained program of sanitary education at the community level. Next slide please.
  6. Also it was recently published the Guide for the implementation and demonstration of sustainable alternatives for the integrated control of malaria in Mexico and Central America as a joint effort of the Mexican health authorities, CEC, PAHO, and the representatives from the ministries of health of the participating countries. This manual is a standardized guide for the development of the demonstration projects, yet aware and taking into account the particularities of each country. Next slide please.
  7. In relation to dissemination, the project’s webpage is an important tool of communication among stakeholders and a source of information for visitors. Next slide please.
  8. The highest organ of the project is the Steering Committee, which is composed by representatives of the ministries of health, PAHO, UNEP/GEF, CEC, CCAD and observers such as the World Bank, UNDP, NGOs and other relevant cooperation agencies. Meet once a year to approve the work plans of the countries, the terms of reference of the demonstration projects and provide advisory functions. Then, the Regional Operational Committee responsible for overseeing the implementation of the project and composed by the Regional Coordinator, the 8 Focal Points (from the health sector), the 8 National Coordinators and representatives from NGOs and the Civil Society. The next level of organization is the National Committee, composed by the National Focal Point, the National Coordinator and representatives from the ministries of the Environment and Agriculture, as well as a representative from Customs or Immigration Representative. With an Advisory Committee composed by Universities, Research Institutions, the Civil Society, Organizations and NGOs with activities related to the project. The organization at the local level is the Working Groups for each Demonstration Projects, composed by the National Coordinator, the Focal Point and representatives from the ministries of the Environment and Agriculture. With an Advisory Committee with representatives from the local government, NGOs and the Civil Society. Next slide please.