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Flash Speed. Lowest Dose.
SOMATOM Definition Flash




Answers for life.
SOMATOM Definition Flash
 SOMATOM Definition Flash
Siemens CT Vision
     Siemens CT Vision
           Today’s reality                                        product development, and design, relies
                                                                  upon the advice and recommendations
              The justification for the existence of the          of external medical experts to determine
              entire medical industry is, of course,              our focus – and this focus has been on
              better healthcare for all patients. But the         the needs and demands of our end users.
              realities of clinical practice often make this      Over the years, this focus has been fine-
              simple-to-understand goal quite difficult           tuned in four key areas:
              to realize: stay within budgets, reduce             • to lead technological and medical
              hospital stays, speed up time to diagnosis,           advancement
              and deal with personnel issues, while               • to maximize workflow efficiency
              maintaining high clinical standards and             • to make state-of-the-art CT affordable
              volume/throughput. At the same time,                • to set the standard in customer care.
              patients demand better and faster results.
                                                               Our vision
           Our approach
                                                                  As a partner of our customers, we create
              In order to meet our share of responsibility        CT innovations, that lift clinical practice
              in addressing these challenges, Siemens,            to a next level of excellence and enable
              from the earliest stages of research,               wide access to better patient care. We




4
believe that even the farthest technical      Patient-centric productivity                     Siemens CT Vision                         4
   horizons are temporary and can be
   surpassed with consistent dedication             Now, we are again setting the bar higher      SOMATOM Definition Flash                  8
   to improved healthcare. This visionary           with FAST CARE technologies. Fully
   approach, backed up by the, by far, largest      Assisting Scanner Technologies (FAST)                Split-Second Scanning             10
   R&D budgets in the healthcare industry,          make complex procedures faster, more                 Defining Low Dose CT              22
   has made Siemens the undisputed inno-            intuitive, and more reproducible than ever.          Dual Source DE for all Patients   34
   vation leader in CT over the last 35 years.      For example, preparing an anatomically
   And our ambitious global team continues          correct reconstruction of the whole spine     Customer Care                            46
   to set the trend in an always changing           now takes only 30 seconds, compared to
   environment, providing Answers for Life.         30 minutes when doing it manually. At the     Configuration Overview                   48
                                                    same time, our Combined Applications to
Leading patient care                                Reduce Exposure (CARE) are now stream-
                                                    lined to make dose reduction easier for all
   Today, more than 700 institutions                examinations while providing a transparent
   worldwide have already taken this                dose-saving management. FAST CARE
   opportunity to improve patient healthcare        delivers a new dimension in clinical
   and push their clinical boundaries to a          efficiency and patient care. We call it:
   higher level utilizing Dual Source CT.           patient-centric productivity.




                                                                                                                                                5
6
7
Flash speed.
          Lowest dose.
     SOMATOM Definition Flash
     Flash speed                                     children, patients who cannot hold their       complex CT procedures: the scanning
                                                     breath for long), thus causing no              process becomes more intuitive, more
        The SOMATOM® Definition Flash opens a        time-consuming interruptions in your daily     automated, and results become more
        door to new levels of patient friendliness   practice. And now Siemens is once again        reproducible. Integrating the capabilities
        with the speed to cover the entire thorax    redefining speed: the new SOMATOM              of the recently developed syngo®.via*
        in less than a second – if necessary even    Definition Flash, with the new FAST CARE       image management platform with its
        without a breath hold. A whole-body scan     technology platform, allows you to             many powerful automated preprocessing
        requires only five seconds, while for        maximize clinical outcomes – meaning           steps and intuitive user interface, the
        perfusion or dynamic vascular imaging        you will have the best possible clinical       complete examination – from scan
        long-range scans become routine and          results, but with significantly less           preparation, scanning, reconstruction, and
        pediatric scans become sub-second            resources bound to the CT system. The          data assessment – is streamlined, leading
        procedures. Your patients will be off the    ultimate goal is to provide you with more      to a fast and reliable diagnosis with less
        table faster than ever before – with         time for patients and diagnosis – in effect,   patient burden. Ultimately, the combination
        positive feelings about their scan           patient-centric productivity. Our Fully        of highest image quality and highest
        experience. Flash is also the solution for   Assisting Scanner Technologies (FAST) on       patient-centric productivity is the lever to
        scanning your most difficult patients        the new SOMATOM Definition Flash               maximizing your clinical outcomes.
        (i.e. obese and trauma patients, restless    simplify typically time-consuming and



8
Lowest dose                                      With the new SOMATOM Definition Flash           Add SAFIRE**, the first, raw-data-based
                                                 with FAST CARE, Siemens introduces              iterative reconstruction, and define low
   Maybe even more important – and               several innovative Combined Applications        dose for all body regions to take best care
   impressive – is the incredible reduction in   to Reduce Exposure (CARE). CARE kV, for         of your patients’ well-being.
   dose for all scans, resulting, e.g. in dose   instance, is the industry’s first tool that
   down to sub-mSv for cardiac imaging.          automatically solves the complex equation
   Now in its second generation, Dual Energy     for optimal image quality at lowest
   automatically provides a second contrast      possible dose for each individual CT exam
   for the best possible diagnosis and added     while considering tube voltage, tube
   diagnostic confidence so that each scan       current, and contrast changes at different     *syngo.via can be used as a stand-alone device
   can now become a Dual Energy scan. At         voltages and attenuation. This allows you       or together with a variety of syngo.via-based
   the same time, X-CARE protects individual     to benefit from the industry’s widest tube      software options, which are medical devices in
                                                                                                 their own rights.
   organs and the most radiation-sensitive       voltage range – not only 140 kV for
   body regions – for example, female            bariatric imaging but now, if necessary,
                                                                                               **The information about this product is being
   breasts – by accurately and efficiently       also down to 70 kV for new safety and           provided for planning purposes.
   minimizing exposure while preserving          image quality standards in pediatric            The product is pending 510(k) review, and is
   image quality.                                imaging.                                        not yet commercially available in the U.S.




                                                                                                                                                  9
10 Split-second scanning
Split-Second
Scanning
How often has your daily practice been interrupted or delayed by fragile,
sick, or traumatic patients who either cannot hold their breath or become
impatient during regular scan procedures? Finding a solution to these
hindrances is what has motivated us to design the world’s fastest CT, by
utilizing Dual Source for Flash-like scan speeds of up to 458 mm/s.

With Flash Spiral scanning, holding breath and motion lose their
significance, making the SOMATOM Definition Flash the optimal patient-
friendly CT. We introduce you to the new, cutting-edge of FAST CARE
technology that raises the standard of your patient-centric productivity,
e.g. through FAST Cardio Wizard, that breaks down the restrictions of
previous CT scanning in cardiology. Today, split-second scanning is
proving its value in actual practice. Emergency department trauma scans
of an entire body in less than five seconds with dose usually under 5 mSv
have also been made possible by the Flash’s speed. Now, with the help of
the FAST Spine feature, making the preparation of complex vertebrae
and disc reconstructions a matter of one click and 30 seconds, we take
trauma imaging and neurological CT examinations to the next efficiency
level for earlier and more accurately targeted treatment.




                                                                            11
Introduction
            Split-Second Scanning


                < 1 sec
                                                             Body imaging in adult and                            Definition Flash with FAST CARE now
                                                             pediatric patients                                   offers Siemens’ unique FAST (Fully
                                                                                                                  Assisting Scanner Technologies) platform
                                                                Scanning an entire thorax in only                 to support you in finding and applying the
                                                                0.6 seconds for motion-artifact-free              ideal settings for every individual
                                                                studies that revolutionizes triple-rule-out       examination to get to a safe, sound, and
     Tube 1 Tube 2                                     Vol
                                                                protocols. The scan speed is fast enough          sustainable diagnosis.
   Sub-second thorax scan for triple-rule-out and a dose        to image the thorax without any breath
   below 5 mSv.                                                 hold and also produces crystal clear           Cardiac imaging in a quarter
                                                                imaging of the coronary arteries, thus         of a heartbeat
                < 1 sec                                         routinely enabling sub-second triple-rule-
                                                                out with less than 5 mSv dose.                    The system’s unique split-second scanning
                                                                                                                  capability allows scanning the heart in
                                                                Bringing this scan speed to imaging               only 250 ms, a quarter of a heartbeat.
                                                                children makes sedation a thing of the            Together with its highest temporal
                                                                past. Now Flash Spiral scans are                  resolution of 75 ms, available in all cardiac
                                                                consistently fast enough to produce sharp         scan modes, it freezes any cardiac motion
     Tube 1 Tube 2                                     Vol
                                                                pediatric images without sedation. This           safely, irrespective of the heart rate.
   Sub-second pediatric scan without the need for sedation      shortens prep time, eliminates repeating
   or anesthesia.                                               scans due to motion, and reduces risk as       Fastest scanning preparation
                                                                well as anxiety.
                < 4 sec                                                                                           The challenge for each CT scan is to find
                                                             Fastest emergency CT                                 and apply the ideal settings for every
                                                                                                                  individual patient, but at the same time
                                                                For several years now, CT has been the            achieve a high degree of reproducibility.
                                                                ideal modality for trauma cases. However,         Now, with FAST, scan and recon planning
                                                                in the most severe cases the time required        can become as fast and easy as just
                                                                to produce useful images often placed the         one click.
     Tube 1 Tube 2                                     Vol
                                                                patient at risk. With Flash speed, scan time
   Whole body imaging in less than 4 seconds without            is no longer an issue. The new SOMATOM
   motion artifacts.


12 Split-second scanning
Automated scan and recon                           possible. FAST Cardio Wizard helps you
planning                                           achieve high-quality clinical outcomes in
                                                   every situation.                              Flash Spiral scanning –
   Decisive for the ideal settings for scan,
   reconstruction, and image evaluation are     Ready for review in one click                    no breath hold required
   the organs and body regions. Based on the
   respective organ, the chosen examination        FAST Spine, another prominent feature
                                                                                                 Sharp coronaries at all heart rates
   type, and, at the end, also expected            of the FAST technology, enhances rapid        – even without beta-blockers
   images, in-depth knowledge of the               trauma and neuro imaging, saving up to
   appropriate system settings is normally         30 minutes with a single click compared       Pediatric scans without sedation
   required. Imagine the time the system           to conventional workflows. Again easing,
   can save you by automatically planning          accelerating, and standardizing the           Whole body trauma scan < 4 sec
   the subsequent reconstruction fields in         workflow in CT scanning.
   a whole body trauma. The SOMATOM                                                              Both guided and standardized
   Definition Flash with FAST and syngo.via     syngo.via-based diagnosis                        cardiac workflow
   now automatically assist you in solving
   this challenge, making possible even            Let us look at only one example of more
   shorter time to diagnosis and more              than 17 functions that syngo.via, the
                                                                                                 Accurate spine recons with
   interaction with patients.                      outstanding multimodality imaging             just a single click
                                                   platform, performs: a triple-rule-out
All heart rates, all patients                      assessment in less than four minutes          Immediate, organ-based scan
                                                   and automatically (at no click), coronal
   Not only does the selection of the              and sagittal images for your referring
                                                                                                 planning
   appropriate scan mode for imaging every         physicians located anywhere in your
   cardiac patient demand expertise, but also      clinical network. The reading physician
   the preparation for image evaluation is         can immediately start with the evaluation
   anything but trivial. It is important that      of the case without wasting efforts in case
   you feel safe in having done everything in      preparation.
   order to achieve the best clinical outcome




                                                                                                                                       13
How it works
            Flash Spiral



                   Even the most advanced single-source CTs        The SOMATOM Definition Flash guarantees
                   are limited in their scan speed by the          fast and accurate ED imaging by putting
                   maximum table feed that can be used and         you in the position to achieve earlier and
                   still allow the acquisition of contiguous       more accurately targeted treatment
                   data. The SOMATOM Definition Flash              decisions that positively affect the patients
                   breaks through this barrier primarily by        30-day adverse event rate and reduce
                   simultaneously integrating data from a          repeated visits.(2)
                   second source during the scan. By
                   combining this Dual Source technology        Revolutionizing the
                   with fastest available hardware              triple-rule-out
                   components, including a gantry that
                   rotates at 0.28 seconds, a patient table        In case of acute chest pain, scanning
                   that can handle immense table feeds, and        with the SOMATOM Definition Flash
                   ultra-fast data transmission technology,        significantly saves time because it is now
                   makes possible the fastest scan mode in         possible to assess pulmonary arteries,
                   CT history. The result is an unprecedented      coronary arteries, and the aorta in a single
                   scan speed of up to 458 mm/s, fast              split-second scan. Scientific validation in
                   enough to scan an entire adult patient          large cohorts demonstrate impressive
                   in less than four 4 seconds.                    results. Due to the SOMATOM Definition
                                                                   Flash’s split-second scanning capabilities
             Increased patient friendliness                        physicians obtain “motion-artifact-free
                                                                   and accurate visualization” in these
                   Patients who cannot hold their breath or        challenging examinations “at a very low
                   suffer from shortness of breath, patients       radiation exposure.”(2) Mean scan times are     Single-source CT requires slower table feeds to prevent
                   who are restless or impatient, who are          0.7 seconds while a radiation dose of only      gaps in the acquired volume (bottom).
                   uncooperative, obese patients or young          4.1 mSv or less is applied. Researchers find
                   children, are no longer a problem. Due to       that the Flash Spiral technology “has the
                   its unprecedented scan speed, the Flash         potential to revolutionize triple-rule-out
                                                                                                                   Source
                   Spiral mode even stops motion entirely,         protocols.”(1)                                  1: Barns E. et al, High-pitch DSCT offers speedy images;
                   preventing image artifacts that might                                                              www.AuntMinnie.com, Nov 30, 2009.
                   obscure image quality and affect your                                                           2: Press release, Andrew Stewart, Radiology Manager,
                   sound diagnosis.(1)                                                                                St George’s Hospital, UK, published online, Jan 1, 2010.

14 Split-second scanning
Barrier-free pediatric                                       Avoiding repetition of scans
imaging
                                                                    Another and widely underestimated
   Bringing this scan speed to imaging                              risk factor is eliminated as well by the
   children, the most delicate patient group,                       Flash Spiral technology: the unnecessary
   opens new possibilities by eliminating                           repetition of scans in young children due
   the need for sedation or anesthesia.                             to failed sedation, which unfortunately
   Researchers state that mean examination                          is the case in 29% of conventional
   times of only 0.49 seconds provide                               examinations, shown in a large trial.(2)
   highest image quality making sedation
   or controlled ventilation unnecessary,                           Sub-second scanning of up to 458 mm,
                                                                                                                          Tube 1    Tube 2
   while maintaining low radiation dose                             with a wide 78 cm bore for unrestricted
   values.(1)                                                       access to your most sensitive patients,
                                                                    makes a true difference in your pediatric   Dual Source CT combines the data from two detectors for
   Being independent of this time-consuming                         scanning, from saving prep time and         faster table feeds above a pitch of three for revolutionary
   and potentially dangerous procedure can                          staff, repeating scans due to motion, to    triple-rule-out scanning and barrier-free pediatric imaging
   save you up to 80 minutes of preparation                         reducing risk as well as anxiety. Yet       without sedation.
   time and involves less personnel.                                another proof for the SOMATOM Definition
   A positive economic side effect of the                           Flash being the healthiest CT available.
   SOMATOM Definition Flash for pediatric
   imaging is that you can do without the
   expensive services of the anesthetist.




   Source
   1: Lell MM. et al, Invest Radiol. Sep 17, 2010. [Epub ahead of print].
   2: Malviya S. et al, British Journal of Anesthesia 84 (6): 743–8 (2000).

                                                                                                                                                                              15
How it works
            FAST Cardio Wizard



             All heart rates, all patients                        Guidance for high-quality
                                                                  clinical outcomes in every
                   The SOMATOM Definition Flash is the
                   fastest cardiac scanner in the industry,       situation
                   offering a true single-segment temporal
                   resolution of 75 ms. Its Flash Spiral             But cardiac CT examinations are also
                   acquires the entire heart in around               among the most sophisticated and
                   250 ms – within a single heartbeat.               demanding procedures in CT, requiring
                   It alternatively enables robust diagnostic        careful preparation and a high degree of
                   outcomes, even in the presence of high            expertise. All the more, it is important that
                   heart rates and arrhythmia, and has been          the user feels sure that he has done
                   repeatedly proven by a wide range of              everything correctly in order to achieve
                   clinical studies. This permits imaging the        the best clinical outcome possible and to
                   heart without the clinical, workflow, and         avoid any unnecessary radiation of the
                   financial aspects of utilizing beta-blockers      patient. Additionally, it allows you to
                   when using the Flash cardio sequence.             define your individual institutional guided
                   The realities of healthcare today often do        cardiac workflow for standardization to
                   not permit the interruptions in workflow,         guarantee continuous high-quality clinical      The modifiable text in the guided workflow allows you to
                   longer patient preparation times, and use         outcomes in every situation.                    define your standards and quality goals that users have to
                   of personnel required by the use of beta-                                                         follow in order to always achieve an optimal cardiac scan.
                   blockers. Not to mention the fact that            Therefore, the new SOMATOM Definition
                   some patients should not receive beta-            Flash offers the FAST Cardio Wizard,
                   blockers, such as in certain cases of             explaining to the operator on a step-by-
                   pulmonary disease. All this makes the             step basis what needs to be done to
                   Flash Cardio Sequence the industry’s most         achieve an optimal cardiac scan, either in
                   versatile low dose mode for cardiac               real-time when preparing a scan or for
                   imaging.                                          training purposes.




16 Split-second scanning
How it works
 FAST Planning



 Fastest emergency CT through                     FAST Planning uses defined
 automated planning                               anatomical landmarks to set the
                                                  correct recon ranges within a large
    In time-critical emergency situations,        scan field of view – as in trauma
    long scan ranges involving different body     imaging – for faster results when
    regions and organs are common. The            every second counts.
    planning of the scan and reconstruction
    field of view is prone to error and eat up
    precious time to diagnosis.

    FAST Planning focuses explicitly on this
    critical part of the scan process. Based
    on the topogram, FAST Planning assists
    the scan and reconstruction planning to
    provide an easier, faster, and standardized
    workflow in CT scanning. The selection of
    the anatomical region of interest (ROI)
    from a list automatically defines
    prospectively the scan and reconstruction
    ranges. The scan ROIs are automatically
    detected based on the characteristics of
    the organ that is to be scanned. In
    addition, the corresponding scan ranges
    are proposed in the topogram as well. In
    the case of head scans, the iso-center is
    automatically adapted according to the
    position of the patient’s head to prevent
    cutting off important information during
    the emergency examination.




                                                                                        17
syngo.via Additional Benefits with syngo.via




             Make lifesaving decisions,
             when every second counts …
                   Acute Care imaging often requires
                   multiple clinical disciplines such as
                   radiologists, cardiologists, neurologists,
                   and trauma surgeons to review images
                   to develop a structured and prioritized
                   treatment plan. syngo.via’s unique
                   information sharing makes it easy to
                   involve all required disciplines into the
                   therapeutic decision-making process.

                   The client/server architecture allows you
                   to access the data independently with
                   up to five users for fast parallel reading.
                   It allows clinicians to review the same
                   images on their individual workplaces         For example, it enables you to conduct       Dual-monitor layout for instant emergency reading
                   to discuss decisions remotely.                a thorough analysis of the major blood       process. This is the first view directly after loading
                                                                 vessels of the body with their curved        the patient.
                   The Acute Care Engine helps you in more       multi-planar reformations (MPR) and
                   demanding cases by automatically adding       appropriate display layouts the moment
                   incremental information for your diagnosis    you open the case. Additionally, it
                   and supports you with a powerful set of       automatically provides you with coronal,
                   intelligent tools.                            sagittal reconstructions of the patient’s
                                                                 data that can be displayed in the entire
                                                                 clinical network such as the ICU, the PACS
                                                                 workplace, the OR, or when you discuss
                                                                 the patient’s diagnosis in your office.


18 Split-second scanning
Rule out coronary heart                                           The syngo.CT Cardiac Function – as part of
disease in under a minute                                         the CT Cardio-Vascular Engine – allows
                                                                  you to read and diagnose CT angiography
   The moment you open a cardiac case, the                        images of the left side of the heart for the
   Automated Case Preparation has already                         evaluation of ischemia or cardiomyopathy.
   preprocessed the images and displays
   them in your appropriate layout together                       Additionally, the application can evaluate
   with the adequate evaluation tools. This                       the late or early myocardial enhancement
   means that you can immediately start                           of single energetic CT data which is
   evaluating the coronary vessels, the                           displayed as a color overlay. The Cardio-
   functional parameters, and the prepared                        Vascular Engine’s Pro level provides right
   calcium score.                                                 ventricular volumetric analysis,* which
                                                                  may have prognostic value for congestive
   The comprehensive layout for display of                        heart failure, chronic pulmonary disease,
   multiple CPRs permits the review of the                        and pulmonary emboli.
   coronary tree at the blink of an eye. All
   your findings and key images are collected
   in the Findings Navigator on-the-fly as you                                                                   Single-click stenosis aneurysm measurement.
   read the case. Your result: rule-out and                                                                      Three reference lines are already predefined.
   reporting of coronary artery disease in less
   than a minute.




  *The CT Acute Care Engine is pending 510(k) review and is not yet commercially available in the U.S.


                                                                                                                                                                 19
Split-second scanning
            Clinical Results




                Motion-free emergency room trauma Flash Spiral scans of an entire body in   Split-second scanning of the human heart with Flash
                less than four seconds with dose usually under 5 mSv.                       Spiral in only 250 ms for motion-free and sharp coronary
                                                                                            arteries due to unmatched 75 ms temporal resolution.
20 Split-second scanning
Organ-based setting of scan and recon ranges with FAST Planning for a fast and more       Restless children or patients who cannot hold their breath
standardized workflow at the scanner. FAST Spine allows the preparation of anatomically   no longer cause time-consuming interruptions.
aligned spine recons with just a single click.
                                                                                                                                                       21
22 Defining low dose CT
Defining
 Low Dose CT
 Applying the lowest radiation dose possible is of the utmost importance
 for both you and, of course, your patients. Therefore you always want
 to be assured that you have taken every means available to protect your
 patient from unnecessary radiation. This desire lies at the heart of
 our CARE (Combined Applications to Reduce Exposure) research and
 development philosophy. Consequently, with Siemens’ continuing effort
 to achieve highest dose protection, the new SOMATOM Definition Flash
 now combines all features to reduce radiation as low as possible: next to
 its already outstanding dose protection portfolio from the initial product
 generation, it now adds a wide range of new and improved dose
 reduction features.

 CARE kV, for instance, is the industry’s first tool for automatically solving
 the complex equation for optimal image quality at lowest possible dose
 for each individual CT exam while considering tube voltage, tube current,
 and contrast changes at different voltages and attenuation. This allows
 you to benefit from the industry’s widest tube voltage range – not only
 140 kV for bariatric imaging but now, if necessary, also down to 70 kV
 where the Definition Flash sets new standards in pediatric safety.

 Add the first, raw-data-based iterative reconstruction SAFIRE* and define
 low dose for all body regions to take best care of your patients well-being.


*The information about this product is being provided for planning purposes.
 The product is pending 510(k) review, and is not yet commercially available in the U.S.




                                                                                           23
Introduction
            Defining Low Dose CT



                                                              Sub-mSv heart –                                   CARE kV – solving a complex
                                                              the ultimate CARE feature                         equation
                                                                 Discussions regarding dose in cardiac             But CT scanning is not only about adapting
                                                                 scanning have changed because dose                mAs values: the right kV settings play an
                                                                 values down to under 1 mSv are so                 equal, if not more important, role in
                                                                 frequent that Sub-mSv heart can be                choosing the right parameter to achieve
                                                                 considered routine for Siemens SOMATOM            optimal clinical outcome at lowest
                                                                 Definition Flash owners. Such low routine         possible dose. Siemens’ unique CARE kV
                                                                 values have opened realistic discussions          now addresses this consideration, and
                                                                 about the use of Flash Spiral for early           supports the user in exploiting the
                                                                 detection of coronary artery disease.             remaining dose-saving capabilities in
                                                                                                                   kV adaptation.
                                                              Optimizing tube current
                                                              and voltage
                            < 1 mSv
                                                                 As early as 1994, Siemens introduced the
                                                                 first versions of CARE Dose4D to actively
   Flash Spiral allows for ultra-fast spiral acquisition at      modulate the applied power for scans
   75 ms temporal resolution with scan speed of up to            depending on the patient’s anatomy. With
   458 mm/s for maximum dose efficiency in your daily            FAST CARE the configuration options have
   clinical practice.                                            now been made more flexible and can be
                                                                 perfectly adjusted for every patient so that
                                                                 you can achieve lowest possible dose at
                                                                 optimal image quality in every
                                                                 examination.




24 Defining low dose CT
Taking care of children                              Preventing unnecessary
                                                     radiation
   The Flash Spiral scan has proven to be                                                              Routine Sub-mSv cardiac CT
   a robust method for scanning children and            SOMATOM Definition Flash eliminates
   infants without sedation while providing             unnecessary pre- and post-spiral
                                                                                                       opens the door to early detection
   high image quality at lowest possible                over-radiation with its two Adaptive Dose
   dose.(1)                                             Shields offering dose reductions up to
                                                                                                       Lowest dose in all organs
                                                        25%. It also protects dose-sensitive body
   With CARE Child, offering the 70 kV                  regions, such as the female breast,
                                                                                                       Adaptive Dose Shields eliminate
   STRATON tube redesign together with a set            eyeballs, the thyroid glands, or the           unnecessary dose
   of dedicated pediatric scan protocols, the           gonads, through X-CARE with possible
   new SOMATOM Definition Flash offers a                dose reductions up to 40% while                Protect radiation-sensitive organs
   unique solution to provide even healthier            preserving the image quality.
   scanning for your youngest patients.                                                                Dose reductions in a wide range
   With CARE kV you now benefit from the             Iterative reconstruction                          of protocols with iterative
   industry’s widest tube voltage range –
   down to 70 kV where the new SOMATOM                  Siemens now introduces SAFIRE*, the first      reconstruction
   Definition Flash sets new standards in low           raw-data-based iterative reconstruction,
   dose pediatric imaging.                              that is a unique approach allowing for up
                                                        to 60% additional dose savings.




                                                       *The information about this product is being
   Source                                               provided for planning purposes.
   1: Lell MM. et al, Invest Radiol. Sep 17, 2010.      The product is pending 510(k) review, and is
   [Epub ahead of print].                               not yet commercially available in the U.S.

                                                                                                                                            25
How it works
            Sub-mSv Heart



                                                       20 mSv
                                                                   Dose down to below 1 mSv                            Low dose cardiac for all
                                                                                                                       heart rates
                                       Single source




                                                                      With the SOMATOM Definition Flash,
                                                       15 mSv         discussions regarding high dose versus              When fully flexible X-ray pulsing meets
                                                                      low dose cardiac scanning will change,              75 ms of temporal resolution, the result
                                                       10 mSv         because, even under unfavorable                     is the Flash Cardio Sequence, the most
                                                                      conditions, the patient exposure with the           versatile low dose cardio scan mode on
                                                                      SOMATOM Definition Flash is less than               the market.
                                                       5 mSv          what is required for diagnostic cardiac
                                                                      cath. Many clinical trials demonstrate that         The intelligently triggered sequence shuts
                                                       1 mSv          high dose cardiac CT no longer exists with          off radiation in the systolic phase when
                                                                      Siemens equipment.(1, 2, 3) With Flash Spiral,      not required and dynamically reacts to
   Single-source cardiac spiral scanning requires                     dose values down to under 1 mSv –                   irregularities during the ECG trace. The
   overlapping data acquisition, resulting in relatively high         especially important for the most dose-             real-time ECG monitoring reacts instantly
   patient exposure (top).                                            sensitive patients – are so frequent they           and stops the scan until the heart rate
                                                                      can be considered routine.                          becomes stable again. This arrhythmia
                                                                                                                          compensation method allows for high
                                                       5 mSv
                                                                      Such low values can open realistic                  dose savings and an increased robustness
                                                                      discussions about the use of CTA for early          of the scan.
                                                       4 mSv
                                                                      detection of coronary artery disease,
                                                       3 mSv          taking advantage of its ability to scan the         For the first time, a step-and-shoot mode
                                                                      entire heart in only 250 ms – a quarter             is robust and fast enough to freeze the
                                                       2 mSv          of a heartbeat. And, for less favorable             heart and visualize the coronary arteries
                                                                      conditions, such as high heart rate or              even at high heart rates, thus allowing
                                                       1 mSv          arrhythmia, the Flash Cardio Sequence               even low dose cardiac CT without the
                                       Flash




                                                                      with its automated arrhythmia                       need for beta-blockers.
                                                                      compensation still allows dose below
                                                                      diagnostic cath. Its unique dual pulsing            Source
   Flash Spiral with Dual Source CT allows for ultra-fast spiral      even calculates the heart’s ejection                1: Leschka S. et al, Eur Radiol. 2009 Dec; 19(12): 2896–903.
   acquisition for maximum dose efficiency in your daily              fraction.                                           2: Lell M. et al, Eur Radiol. 2009 Nov; 19(11): 2576–83.
   clinical practice (bottom).                                                                                            3: Achenbach S. et al, Eur Heart J. 2010 Feb; 31(3): 340–6.


26 Defining low dose CT
How it works
 CARE kV and CARE Child



 Real-time dose modulation                          CARE kV, an extension of CARE Dose4D,
                                                    can now automatically suggest kV and
    CARE Dose4D aims to regulate the                effective mAs to optimize the contrast-to-
    mAs so that image quality is uniform            noise-ratio (CNR) of the image while
    across the whole scan range. CARE Dose          limiting the applied dose. The system’s
    Configurator provides the user the ability      proposal is based on the attenuation as
    to select reference curves for each body        measured in the topogram and the user-
    region and for each body habitus                defined acquisition type (non-contrast,
    individually. With the new SOMATOM              bone, soft tissue, vascular). The system
    Definition Flash with FAST CARE the             also identifies bariatric patients and
    configuration options have now been             consequently sets the parameters to make
    made even more flexible for perfect             full use of the system’s reserves. CARE kV                                  70 kV
                                                                                                                                80 kV
    adjustment for every patient.                   is, of course, fully customizable, meaning                                 100 kV
                                                    that the user can choose the degree of                                     120 kV

 Solving a complex equation                         system assistance between none, semi,
                                                                                                                               140 kV

                                                    and full.
    The dose saving and image quality
    potential of the right kV settings play an   Taking care of children
    equal, if not more important, role to
    achieve optimal clinical outcomes. But          With the new improved STRATON tube
    changing kV values always comes along           the voltage range is extended from 80
    with the need to adapt all other values         down to 70 kV where it sets new standards
    according to the respective patient and         in low dose pediatric imaging with CARE
    the proposed examination. Unfortunately,        Child. The new 70 kV scan mode further
    up to now this had to be done manually          reduces the dose to small pediatric or        Example: For a vessel examination of a small
    and required a lot of expertise. These          neonate patients. These dedicated             patient, CARE kV proposes scanning with 70 kV
    dependencies are described in a complex         pediatric scan modes take care of the well-   and sets the other values for optimal image quality
    physical equation, so that often the full       being of our youngest patients. Overall,      at lowest dose accordingly.
    potential for dose reduction remained           with these features, an additional dose
    untapped with 120 kV being used in              reduction of up to 60% is possible and
    almost every adult patient.                     easy to achieve in clinical practice.


                                                                                                                                                        27
How it works
            X-CARE


                                                                                                             X-ray low

             Additional dose reduction
             of up to 40%
                   Siemens has recognized the importance
                   of dose-sensitive scanning, especially for
                   female patients, but also when directly
                   radiating the eye lens or the thyroid gland.
                   A simple but effective approach to lower
                   dose for the most dose-sensitive body
                   regions is partial CT scanning, that has
                   been integrated into dedicated protocols                                                  X-ray on
                   of the SOMATOM Definition Flash.
                   It protects these areas from direct X-ray      Conventional scanning             X-CARE nearly switches the
                   exposure by nearly switching the X-ray         applies radiation permanently     tube current off within a
                   tube off for a certain range of projections,   during the full rotation, thus    certain range of projections,
                   while automatically adjusting tube             resulting in direct exposure of   minimizing direct exposure
                   currents for the remaining projections         radiation-sensitive organs,       for highly dose-sensitive
                   to prevent deteriorating image quality.        for example for the breasts.      body regions.

                   The result with X-CARE is reduced
                   sensitive-area exposure up to 40% without
                   loss of image quality.




28 Defining low dose CT
How it works
 SAFIRE



 Iterative Reconstruction                           with homologous reference data. This         Standard Filtered             SAFIRE*
                                                    procedure can be regarded as validating      Back Projection
    SAFIRE* – Sinogram Affirmed Iterative           (or affirming) the current images.
    Reconstruction – for the first time allows
    to utilize the full dose-saving potential       An updated image is then again recon-
    of the iterative reconstruction in clinical     structed, using the detected deviation
    practice. Now, raw-data information             information. In each iteration a dynamic
    (which is visualized in the so-called           raw-data-based noise model is applied
                                                                                                          Raw data
    sinogram) is actually being utilized in         that allows for reduction of image noise
                                                                                                           recon               Raw data   Image data     Image
    the image improvement process.                  without noticeable loss of sharpness. This                                  recon       recon      correction
                                                    optimization process thus makes even
    After the initial reconstruction using the      better use of the diagnostic information
    weighted filtered back projection (WFBP)        contained in the raw data. Using multiple
    the first iterative reconstruction loop is      iterations, geometrical imperfections of
    performed. The CT images are retrans-           the WFBP are corrected in addition to
    ferred to raw data which models all             incrementally reducing image noise.
    relevant geometrical properties of the CT
    scanner. This step reproduces CT raw data       With this, SAFIRE* allows for a radiation      Ultra-fast reconstruction      More powerful dose
    like a real scanner does. By comparing          dose reduction of up to 60% or improved        without iterations             reduction than image-
    this synthetic raw data with the acquired       image quality in regards to contrast,          Well-established image         based methods
    data, differences are identified. A further     sharpness, and noise.                          impression                     Well-established image
    iteration loop compares the images                                                             Limited dose reduction         impression
                                                                                                                                  Superior image quality
                                                                                                                                  Fast reconstruction in
                                                                                                                                  image and raw-data space
                                                                                                                                  and improved workflow
                                                                                                                                  with variable settings


   *The information about this product is being
    provided for planning purposes.
    The product is pending 510(k) review, and
    is not yet commercially available in the U.S.

                                                                                                                                                                    29
syngo.via Additional benefits with syngo.via




             CT Acute Care Engine                                       disease, aortic dissection, or pulmonary
                                                                        embolism. syngo.CT Coronary Analysis,
                   Make lifesaving decisions, when every                as a part of the CT Acute Care Engine,
                   second counts …                                      evaluates the coronary status and
                                                                        quantifies stenoses in less than one
                   CT is the modality of choice when it                 minute through Single Click Stenosis
                   comes to diagnostic imaging in acute care            measurement. syngo.CT’s Cardiac Function
                   situations, whether it is for a triple-rule-out      is also able to evaluate whether the
                   of acute chest pain, for stroke assessment,          myocardial function has already been
                   polytrauma, or for acute abdominal pain.             affected by an infarction, while syngo.CT
                   The CT Acute Care Engine provides clinical           Vascular Analysis with VesselSURF is the
                   functionality that delivers decisive results         perfect tool to assess the extent of an
                                                                                                                                    Tube 1     Tube 2
                   for all of these challenging indications.            aortic dissection, or to evaluate a
                   syngo.via’s workflow is another remarkable           pulmonary embolism.
                   feature, as the Direct Image Transfer,                                                             Dual Source CT combines the data from two detectors
                   Study Split for parallel assessment with          Flash Spiral scanning of the                     for faster table feeds above a pitch of three.
                   up to five parallel readers, together with        entire thorax below 4 mSv
                   Automated Case Preparation, make the
                   CT Acute Care Engine the zero-delay                  The prospectively triggered Flash Spiral
                   diagnostic tool. Above all, speed and                scan perfectly meets the need for patients
                   dependability add confidence for critical            who present with acute chest pain to
                   decisions made against the clock.                    exclude coronary artery disease,
                                                                        pulmonary embolism, and aortic
                   The CT Acute Care Engine* provides                   dissection. The average dose for this high
                   comprehensive image-processing                       speed examination is 1.6 mSv for patients
                   functionality for triple-rule-out of acute           who can be scanned with 100 kV protocols
                   chest pain caused by coronary heart                  and 3.2 mSv for patients who can be          * The CT Acute Care Engine is pending 510(k) review and is not yet
                                                                        scanned with 120 kV protocols.                 commercially available in the U.S.




30 Defining low dose CT
The prospectively triggered high-pitch
Flash Spiral scan mode for triple-rule-out
allows motion-artifact-free and accurate
visualization of the entire thoracic vessels,
including the aorta, pulmonary, and
coronary arteries at dose levels, before
unseen, of below 4 mSv.

syngo.via automatically displays the
acquired data in the appropriate layout
and has preprocessed it according to the
triple-rule-out specific (disease-oriented)
workflow for a quick rule-out in less than
four minutes.




                                                Triple-rule-out of coronary artery disease, aortic dissection, or pulmonary embolism in less than four minutes.




                                                                                                                                                                  31
Defining low dose CT
            Clinical Results




                CARE Child, with the 70 kV STRATON tube, defines new low dose   Sub-mSv heart, the ultimate CARE feature. Dose values down to under
                safety and image quality standards in pediatric imaging.        1 mSv are so frequent that Sub-mSv heart can be considered routine for
                                                                                SOMATOM Definition Flash users.
32 Defining low dose CT
Thoracoabdominal aorta examination, including the coronary arteries, with   1.9 mSv low dose Flash Spiral scan together with iterative reconstruction of
dose below 5 mSv, automatically preprocessed in syngo.via, showing aortic   a newborn after perinatal complications.
insufficiency.
                                                                                                                                                           33
34 Dual Source DE for all patients
Dual Source DE
for all Patients
It has always been a CT goal to collect as much information as possible in
order to differentiate tissues. With Dual Energy scanning, the SOMATOM
Definition and SOMATOM Definition Flash open the door to a new world
of characterization, visualizing the chemical composition of material. The
idea of Dual Energy is not new to the CT community. Earlier approaches,
including two subsequent scans at different tube voltages or two
subsequent scans at the same position, failed to seamlessly align the
imaged anatomy and to capture the same phase of contrast
enhancement.

Dual Energy was first successfully introduced into clinical practice with
Dual Source CT, i.e. two X-ray tubes and two UFC (Ultra-Fast Ceramic)
detectors mounted at 90 degrees from each other and perfectly
synchronized during scans. And, to date, Dual Source remains the only
modality that enables the usage of Dual Energy in daily practice at a dose
comparable to a conventional 120 kV scan and with optimum spectra
separation for highest value DE information.

With 12 FDA-cleared applications and more than 700 Dual Source CTs
installed, the number of Dual Energy scans has skyrocketed worldwide
and is expected to continue increasing at an even higher rate. Dual
Energy with Dual Source CT adds the decisive diagnostic confidence for
sustainable and sound treatment decisions – it is the advantage that
proves itself over and over in daily practice.




                                                                             35
Introduction
             Dual Source DE for all Patients



     Selective                                               Dual Source Dual Energy                         Dose-neutral every day
 Photon Shield                                               setting the standards                           Dual Energy imaging
                                                               Dual Source Dual Energy (DE) CT                  An additional benefit is the fact that all
                                                               acquisition provides an expanded set of          renowned dose-saving techniques, such
                                                               diagnostic capabilities and alters CT            as CARE Dose4D, Adaptive Dose Shield,
                                                               imaging in significant ways. Clinicians in       and X-CARE, can be applied to effectively
                                                               700 international institutions, working          achieve dose-neutral Dual Energy imaging
                                                               with SOMATOM Definition and Definition           for everyday usage without a dose
                                                               Flash, are setting the technological and         penalty compared to a conventional 120 kV
                                                               clinical benchmark in Dual Energy                scan.(1, 2, 3) Moreover, with Dual Source
                                                               imaging.                                         Dual Energy you can now get motion-free
         80 kV                               140 kV                                                             diagnostic images with a temporal
 Attenuation B                               Attenuation A     Most important and most obvious with the         resolution of down to 75 ms in Cardiac
                                                               Dual Source approach: detector units can         Dual Energy imaging.
                     Always a dose-neutral
                                                               operate at different tube potentials during
                     second contrast.
                                                               the synchronous CT acquisition. This avoids
                                                               spectral contamination or waste of applied
                                                               dose occurring during kV-switching time
                                                               intervals. Furthermore, the Dual Source
                                                               approach allows the introduction of X-ray
                                                               filters such as the Selective Photon Shield
                                                               for even further spectral separation.




                                                                                                                Source
                                                                                                                1: Schenzle JC. et al, Radiol. 2010 Jun; 45(6): 347–53.
                                                                                                                2: Graser A. et al, Invest Radiol. 2010 Jul; 45(7): 399–405.
                                                                                                                3: Thomas C. et al, Invest Radiol. 2010 Jul; 45(7): 393–8.

36 Dual Source DE for all patients
Dual Energy for all patients                    Already clinical routine
   Dual Source DE brings new levels of             More than 130 peer-reviewed publications    Always second contrast at no dose
   contrast, for instance with Optimum             for our 12 FDA-approved DE applications
   Contrast, to all images over a broad range      provide evidence and identify the
                                                                                               penalty
   of routine examinations. It offers              improvements in clinical outcome as a
   significant patient benefit improving           result of their implementation. 800,000
                                                                                               Wide range of 12 FDA-cleared
   diagnostic outcomes through improved            successful DE examinations have already     applications
   lesion detection, removal of bone and           helped to detect pulmonary embolisms in
   plaque, improved visualization of metal         lung vessels, to directly remove bone and   Optimum Contrast in every image
   prostheses, chemical analysis of normal         plaque in angiographies, to characterize
   and pathologic tissue, and iodine mapping.      renal calculi, or to allow for enhanced     Improved visualization of metal
   It may grant the decisive diagnostic            lesion conspicuity through Optimum
   information for a safe, sound, and              Contrast, or simply to speed up workflow
                                                                                               prostheses
   sustainable diagnosis and treatment             through Virtual Non-Contrast Imaging.
   planning in any of the patients entrusted
                                                                                               75 ms high temporal resolution DE
   to you.                                                                                     freezing any cardiac motion
                                                                                               syngo.via automatic virtual non-
                                                                                               contrast bone and hard plaque
                                                                                               removal
                                                                                               syngo.via auto-preprocessing for
                                                                                               immediate sagittal/coronal display




                                                                                                                                    37
How it works
                                                                                                                     Single-Source CT



             Dual Source Dual Energy (DE)



                     The X-ray tube’s kilo voltage (kV)             Benefits of
                     determines the average energy level of         Dual Source scanning
                     the X-ray beam. Changing the kV setting
                                                                                                                          120 kV
                     results in an alteration of photon energy         Using the two Z-Sharp STRATON tubes,
                     and a changed attenuation of the                  Dual Source data acquisition allows for
                     materials scanned. For instance, scanning         at least 1,152 projections per rotation       Single-source CT only provides one energy level for
                     an object with 80 kV results in a different       and spectrum. This provides homogeneous       morphology imaging.
                     attenuation than with 140 kV. In addition,        image quality over the entire FOV.
                     this attenuation depends also on the type         In spiral mode the same slice is acquired
                     of tissue scanned. While the CT value for         within the same time interval for both
                     iodine is highest at the low-energy scans,        spectra, so the reconstructed images show
                     it can be less than half in the high-energy       no time offset. The fast gantry rotation of   Dual Source CT
                     scans. The attenuation of bones, on the           0.28 seconds, with only 0.24 ms sampling
                     other hand, changes much less when                time, minimizes motion artifacts, while all
                     exposed to low-energy scans compared              renown dose-saving techniques can be
                     to high-energy voltage examinations.              applied, such as CARE Dose4D, Adaptive
                                                                       Dose Shield, and X-CARE. In addition,
                     The material-specific difference in               IRIS and SAFIRE* iterative reconstruction
                     attenuation enables an easy classification        techniques can be applied.
                     of the elementary chemical composition
                     of the scanned tissue. In addition, a fused    Monoenergetic imaging
                     image is provided for initial diagnosis.
                                                                       Using the SOMATOM Definition Flash
                                                                       also allows obtaining monoenergetic CT
                                                                       images. These are similar to images
                                                                       acquired with a synchrotron X-ray beam
                                                                                                                            80 kV                               140 kV
                                                                                                                     Attenuation B                              Attenuation A
                                                                       of single photon energy. The equivalent
                   *The information about this product is being
                                                                       photon energy between 40 keV and
                    provided for planning purposes.                    190 keV (151 steps) can be optimized          Two X-ray sources set to different kV levels simultaneously
                    The product is pending 510(k) review, and          interactively to provide best contrast for    acquire two data sets at different attenuation levels.
                    is not yet commercially available in the U.S.      the lesion of interest.


38 Dual Source DE for all patients
How it works
 Selective Photon Shield
                                                                                                  Without Selective Photon Shield
                                                                                                  number of quanta
                                                                                                                                       80 kV
                                                                                                                                      140 kV
                                                                                                                                      overlap
 Eliminating unnecessary                         Better dose efficiency
 radiation
                                                    While Dual Source technology has already
    An important factor in making dose              overcome this limitation, the Selective
    neutrality viable is the development of         Photon Shield further increases dose
    the Selective Photon Shield that blocks         efficiency by filtering out unnecessary
    unnecessary photons of the X-ray energy         photons of the high-energy X-ray tube.
    spectrum. The result is a much better           The remaining photon spectrum is                          photon energy
    separation of the 80 kV and 140 kV              therefore better focused and more clearly
    images, as the second detector is 25%           separated from the photons emitted by         With Selective Photon Shield
    larger than previously.                         the low-energy tube. The result is a much     number of quanta
                                                    better separation of the 80/140 kV images,
                                                                                                                                       80 kV
    In effect, the Selective Photon Shield          increasing bone-iodine differentiation
                                                                                                                                      140 kV
    assures dose neutrality for single-dose         by up to 80% while reducing overall dose.
                                                                                                                                      overlap
    Dual Energy by avoiding unnecessary             Therefore, the high-quality 80/140 kV
    exposure. Thus it makes Dual Energy as          mode is ideal for the head and extremities,
    dose-efficient as conventional 120 kV           especially CT angiographies.
    scans. So all the diagnostic advantages of
    Dual Energy imaging are now available           The spectral separation through the
    with the same dose as a single energy           Selective Photon Shield on the other hand,
    scan.                                           opens the possibility to use 100/140 kV
                                                    imaging with still 30% better bone-iodine
                                                    contrast and more power reserves for                      photon energy
                                                    cardio, abdomen, pelvis, and larger
                                                    patients in general, making Dual Energy a     The Selective Photon Shield increases energy
                                                    clinical application for all your patients.   separation and reduces unnecessary dose
                                                                                                  by blocking low-energy photons out of the
                                                                                                  high-energy X-ray tube’s spectrum. This
                                                                                                  results in optimal information quality and
                                                                                                  dose neutrality compared to a conventional
                                                                                                  120 kV scan.


                                                                                                                                                 39
How it works
             Optimum Contrast



                                                               Maximizing anatomic                                   the detail from the 140 kV images in non-
                                                               information                                           enhanced areas, an optimized image can
                                                                                                                     be automatically calculated. It is especially
                                                                  Dual Energy can be used to enhance the             helpful in enhancing conspicuity of lesions
                                                                  iodine signal. It is well-known that the           for a safe, sound, and sustainable therapy
                                                                  iodine signal is potentiated at low tube           planning that may improve outcome, cost
                                                                  energies (80 and 100 kV), yet lower tube           effectiveness, and patient comfort.
                                                                  energies are not employed in general CT
                                                                  scanning because of increased noise.            syngo.via enhanced
                                                                  This is what builds the foundation of Dual      DE imaging
                                                                  Energy Optimum Contrast.
   80 kV scan                            140 kV scan                                                                 syngo.via dose not only provides you
   Focus: iodine, high                   Focus: soft tissue    Optimum Contrast                                      with the result images, for instance of
   contrast                              and low image noise                                                         Optimum Contrast, in all standard views
                                                                  The images obtained at 80 and 140 kV               such as coronal, sagittal, and axial. It also
                                                                  automatically exploit the spectral behavior        automatically removes bone and hard
                                                                  of certain materials or tissues in syngo.via.      plaque in the major vessels for a easier
                                                                  Additionally, average images can be                assessment of the true lumen.
                                                                  calculated to provide a ”normal” CT image,
                                                                  because the 140 kV images lack contrast,           With syngo.via clients, your results, such
                                                                  while the 80 kV images are naturally more          as Dual Energy Brain Hemorrhage images,
                                                                  noisy.                                             can be instantaneously displayed in the
                                                                                                                     OR* or the angio suite.
                                                                  By adding more of the contrast
                                                                  information from the 80 kV images in
                 Best of both worlds to maximize                  areas of iodine enhancement, and more of
                 anatomic information: less noise
                 and more contrast than standard                                                                    *Usage of syngo.via for an emergency case
                 CT images.                                                                                          requires customer to provide respective
                                                                                                                     emergency measures in case of non-availability
                                                                                                                     of system or network.


40 Dual Source DE for all patients
How it works
 High Temporal Resolution DE



 Dual Energy Flash Cardio                         Dual Energy Heart Perfused
                                                  Blood Volume
    Another CT first: the SOMATOM Definition
    Flash allows scanning the entire heart,          With its high temporal resolution, Dual
    and then evaluating the coronaries with a        Source CT has greatly improved coronary
    full temporal resolution of 75 ms as well        CT angiography, because it is less sensitive
    as, in a second reconstruction, visualizing      to high heart rates or arrhythmia than
    perfusion defects in the myocardium,             other types of scanners. With Dual
    thus combining the maximum speed of              Energy CT, it is now possible to highlight           80 kV                               140 kV
    Dual Source CT with Dual Energy imaging          iodine content to visualize organ              Attenuation B                             Attenuation A
    in a single scan. This has been made             perfusion. Prospectively triggered
    possible with our latest reconstruction          sequence or retrospectively gated spiral
    technology, that allows achieving Dual           acquisition modes are available for first
    Source temporal resolution from image            pass or late enhancement Dual Energy
    components acquired at different energy          myocardial perfusion studies. The
    levels. The result is the ability to obtain      corresponding syngo Dual Energy Heart
    diagnostic Dual Energy CT images without         PBV software color-codes myocardial
    the use of beta-blockers.                        perfusion, so that both coronary artery        140 ms reconstruction              75 ms high temporal
                                                     morphology and myocardial perfusion            (low spatial frequencies)          resolution reconstruction
                                                     can be assessed in a single CT scan.                                              (high spatial frequencies)



                                                                                                                                       Result: high temporal
                                                                                                                                       resolution DE



                                                                                                         High 75 ms temporal resolution Dual Energy freezes
                                                                                                         even cardiac motion and allows color-coded perfused
                                                                                                         myocardial blood pool evaluation, for example for
                                                                                                         patients suspected of having an acute myocardial
                                                                                                         infarction.
                                                                                                                                                                    41
syngo.via  Additional Benefits with syngo.via




              Speed in routine – power
              in challenging cases
                     The new CT Cardio-Vascular Engine offers
                     excellent functionality for the automatic
                     anatomical evaluation, quantification, and
                     functional assessment of CT angiography
                     images of the heart or the peripheral
                     vessels, while allowing manual interaction
                     for challenging cases at any time.

                     Before you open a case, the Automated
                     Case Preparation has already pre-
                     processed the images, including the Dual
                     Energy direct bone and hard plaque
                     removal and displays them in your
                     appropriate layout together with the
                     adequate evaluation tools.

                     You can immediately start evaluating           syngo.via showing a severely calcified
                     the major blood vessels of the body with       thoracic aorta in which Dual Energy
                     their curved multi-planar reformations         direct bone and hard plaque removal was
                     (MPR) and appropriate display layouts.         automatically applied in the background –
                     Additionally, it automatically provides you    before you opened the case. A single
                     with coronal, sagittal reconstructions of      click on your patient in your private
                     the patient’s data that can be displayed in    Worklist opens the case the way it is
                     the entire clinical network such as the ICU,   displayed here.
                     the PACS workplace, or when you discuss
                     the patient’s diagnosis in your office.                                                    *Not commercially available in the US.


42 Dual Source DE for all patients
From scan to diagnosis                         status of the vascular structures and
in under ten minutes                           the brain tissue for these patients –
                                               from scanning to diagnosis in less than
   CT Neuro imaging is very often a matter     ten minutes including Dual Energy data
   of life-and-death therapeutic decision-     into the disease-oriented workflow for
   making. From infarctions caused by stroke   seamless integration into your clinical
   and extensive bleeding, to subarachnoid     practice. Using data delivered by the
   hemorrhage and a ruptured aneurysm –        Adaptive 4D Spiral, perfusion assessment
   seeing them clearly is essential because    of the brain can easily be integrated in the
   of the huge difference it makes in          assessment. The CT Neuro Engine also
   determining treatment. The new CT Neuro     helps identify fractures after an accident
   Engine provides tools and workflows that    and, for instance, uncovers the potential
   help deliver a complete and accurate        stenosis when looking at the vascularity
                                               of the neck.

                                               If a Dual Energy examination, such as a
                                               Dual Energy Brain Hemorrhage calculation
                                               was made, the data is automatically
                                               displayed together with all your other pre-
                                               processed data. So Dual Energy data,
                                               seamlessly integrated in syngo.via, may
                                               give you the decisive diagnostic
                                               information for taking sound, safe, and
                                               sustainable treatment decisions in any
                                               patient.




                                                                                              43
Dual Source DE for all patie
             Clinical Results




             Single dose Dual Energy shows a lung perfusion defect in the right   Dual Energy direct hard plaque and bone removal for immediate true lumen
             lower segment – unveiling the effect of pulmonary emboli.            assessment. Automatically preprocessed in syngo.via with coronal, sagittal,
                                                                                  and axial reformats for sound treatment decisions.
44 Dual Source DE for all patients
nts




 Monoenergetic imaging, on the right, provides improved visualization of the   Dual Energy Optimum Contrast (right) combines the advantages of low and high kV
 metal screws relative to the surrounding bone tissue.                         CT scans for enhanced lesion conspicuity in iodine-enhanced CT images.


                                                                                                                                                                 45
Customer Care
           Dedicated to Your Success




                   Remain one step ahead and tap the           Upgrades and migration:                          Services and support
                   full potential of your Siemens CT system    Evolve, Expand, Elevate
                   with our customer care program, Life.                                                           Feel confident with our proactive
                   As a worldwide innovation leader in            Stay competitive with up-to-date systems         service solutions
                   medical imaging, Siemens has gained
                   unmatched knowledge in Computed                Due to increasing healthcare demands you         High system availability, diagnostic
                   Tomography. You can profit from excellent      have to stay on the cutting edge to be           confidence, and optimized workflow
                   CT systems and innovative, flexible, and       competitive. We will help you to keep your       are crucial for the success of your
                   comprehensive service solutions that           solutions up-to-date and to keep pace with       CT service. To meet your performance
                   enable you to concentrate on what is           the latest technological advancements            expectations, we systematically focus
                   most important for you: patient care.          through the syngo Evolve program. syngo          on being proactive. Based on real-time
                   The customer care program, Life, is            Evolve offers certainty in budget planning,      system monitoring we detect system
                   the unique solution from Siemens that          feature enhancements for your CT, access         errors and alert you before problems
                   helps you to maximize the return on            to new applications, and lower cost              occur. The Siemens Guardian Program™
                   investment throughout the entire life          upgrades for your CT system.                     helps to make unplanned downtime a
                   cycle of your system.                                                                           thing of the past.




46 Customer Care
Education and training                          Information
                                                and communication
   Broaden your knowledge and expertise
                                                   Be informed – get connected
   Know-how is the key to success. With
   our extensive portfolio of education and        To ensure you are always up-to-date
   training programs you can deepen your           on what is happening in the CT world,
   knowledge and clinical expertise. We            we offer you a variety of information
   show you how to maximize the benefits           services including easily accessible
   that can be achieved with our advanced          information portals, monthly newsletters,
   technology. This will help you to optimize      our customer magazine SOMATOM
   your workflows so you can offer an even         Sessions, and the SOMATOM World
   higher quality of care for your patients.       Summit, our scientific user conference.




                                                                                               47
SOMATOM Definition Flash
            Configuration Overview



             SOMATOM Definition Flash
             with FAST CARE
                   • All routine and advanced                                    • High-speed whole-body coverage at            Access to:
                     applications for clinical practice                            highest spatial resolution
                                                                                                                                • SAFIRE* – the first raw-data-based
                   • Industry’s fastest Flash Spiral                             • Pediatric and bariatric CT imaging with        iterative reconstruction
                     scanning                                                      no patient exclusion
                                                                                                                                • Full FAST functionality like FAST Planning
                   • Full CARE functionality like CARE                           • Two Adaptive Dose Shields blocking             and FAST Spine to raise patient-centric
                     kV and CARE Child, including the                              clinically irrelevant dose in spiral scans     productivity
                     redesigned 70 kV STRATON tube
                                                                                                                                • 3D-guided interventional CT
                   • High-performance image
                                                                                                                                • Ultra-long-range dynamic
                     reconstruction system with
                                                                                                                                  imaging (up to 48 cm) for
                     WorkStream 4D
                                                                                                                                  whole organ coverage
                   • Industry’s highest – heart rate
                                                                                                                                • Scanner-injector coupling including
                     independent – temporal
                                                                                                                                  injector protocol management
                     resolution of 75 ms for all heart
                     rates in cardiovascular imaging                                                                            • Latest syngo.via Engines with automated
                                                                                                                                  preprocessing tools for rapid, sound and
                   • State-of-the-art cardiovascular
                                                                                                                                  sustainable diagnosis
                     imaging
                                                                                                                                • Dose-neutral Dual Energy imaging at
                   • Industry’s widest range of kV
                                                                                                                                  high temporal resolution with 12 FDA-
                     steps and strongest generator
                                                                                                                                  cleared applications
                     power
                                                                                                                                • Dynamic myocardial stress perfusion
                                                                                                                                  imaging

                                                                                                                                *The information about this product is being
                                                                                                                                 provided for planning purposes.
                                                                                                                                 The product is pending 510(k) review, and
                   For more details on FAST CARE benefits for your patients, please visit www.siemens.com/fastcare               is not yet commercially available in the U.S.

48 Configuration overview
Rotation time          0.28 s*
Number of slices       2 x 128
Generator              200 kW (2 x 100 kW)
kV steps               70, 80, 100, 120, 140 kV
Isotropic resolution   0.33 mm
Temporal resolution    75 ms*, heart-rate independent
Max. scan speed        458 mm/s* with Flash Spiral
Table load             up to 300 kg/660 lbs*
Gantry opening         78 cm




*optional




                                                        49
SOMATOM Definition Flash
 SOMATOM Definition Flash
CT definition flash - SIEMENS
CT definition flash - SIEMENS

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CT definition flash - SIEMENS

  • 1. Boosted by syngo.via Flash Speed. Lowest Dose. SOMATOM Definition Flash Answers for life.
  • 2.
  • 3. SOMATOM Definition Flash SOMATOM Definition Flash
  • 4. Siemens CT Vision Siemens CT Vision Today’s reality product development, and design, relies upon the advice and recommendations The justification for the existence of the of external medical experts to determine entire medical industry is, of course, our focus – and this focus has been on better healthcare for all patients. But the the needs and demands of our end users. realities of clinical practice often make this Over the years, this focus has been fine- simple-to-understand goal quite difficult tuned in four key areas: to realize: stay within budgets, reduce • to lead technological and medical hospital stays, speed up time to diagnosis, advancement and deal with personnel issues, while • to maximize workflow efficiency maintaining high clinical standards and • to make state-of-the-art CT affordable volume/throughput. At the same time, • to set the standard in customer care. patients demand better and faster results. Our vision Our approach As a partner of our customers, we create In order to meet our share of responsibility CT innovations, that lift clinical practice in addressing these challenges, Siemens, to a next level of excellence and enable from the earliest stages of research, wide access to better patient care. We 4
  • 5. believe that even the farthest technical Patient-centric productivity Siemens CT Vision 4 horizons are temporary and can be surpassed with consistent dedication Now, we are again setting the bar higher SOMATOM Definition Flash 8 to improved healthcare. This visionary with FAST CARE technologies. Fully approach, backed up by the, by far, largest Assisting Scanner Technologies (FAST) Split-Second Scanning 10 R&D budgets in the healthcare industry, make complex procedures faster, more Defining Low Dose CT 22 has made Siemens the undisputed inno- intuitive, and more reproducible than ever. Dual Source DE for all Patients 34 vation leader in CT over the last 35 years. For example, preparing an anatomically And our ambitious global team continues correct reconstruction of the whole spine Customer Care 46 to set the trend in an always changing now takes only 30 seconds, compared to environment, providing Answers for Life. 30 minutes when doing it manually. At the Configuration Overview 48 same time, our Combined Applications to Leading patient care Reduce Exposure (CARE) are now stream- lined to make dose reduction easier for all Today, more than 700 institutions examinations while providing a transparent worldwide have already taken this dose-saving management. FAST CARE opportunity to improve patient healthcare delivers a new dimension in clinical and push their clinical boundaries to a efficiency and patient care. We call it: higher level utilizing Dual Source CT. patient-centric productivity. 5
  • 6. 6
  • 7. 7
  • 8. Flash speed. Lowest dose. SOMATOM Definition Flash Flash speed children, patients who cannot hold their complex CT procedures: the scanning breath for long), thus causing no process becomes more intuitive, more The SOMATOM® Definition Flash opens a time-consuming interruptions in your daily automated, and results become more door to new levels of patient friendliness practice. And now Siemens is once again reproducible. Integrating the capabilities with the speed to cover the entire thorax redefining speed: the new SOMATOM of the recently developed syngo®.via* in less than a second – if necessary even Definition Flash, with the new FAST CARE image management platform with its without a breath hold. A whole-body scan technology platform, allows you to many powerful automated preprocessing requires only five seconds, while for maximize clinical outcomes – meaning steps and intuitive user interface, the perfusion or dynamic vascular imaging you will have the best possible clinical complete examination – from scan long-range scans become routine and results, but with significantly less preparation, scanning, reconstruction, and pediatric scans become sub-second resources bound to the CT system. The data assessment – is streamlined, leading procedures. Your patients will be off the ultimate goal is to provide you with more to a fast and reliable diagnosis with less table faster than ever before – with time for patients and diagnosis – in effect, patient burden. Ultimately, the combination positive feelings about their scan patient-centric productivity. Our Fully of highest image quality and highest experience. Flash is also the solution for Assisting Scanner Technologies (FAST) on patient-centric productivity is the lever to scanning your most difficult patients the new SOMATOM Definition Flash maximizing your clinical outcomes. (i.e. obese and trauma patients, restless simplify typically time-consuming and 8
  • 9. Lowest dose With the new SOMATOM Definition Flash Add SAFIRE**, the first, raw-data-based with FAST CARE, Siemens introduces iterative reconstruction, and define low Maybe even more important – and several innovative Combined Applications dose for all body regions to take best care impressive – is the incredible reduction in to Reduce Exposure (CARE). CARE kV, for of your patients’ well-being. dose for all scans, resulting, e.g. in dose instance, is the industry’s first tool that down to sub-mSv for cardiac imaging. automatically solves the complex equation Now in its second generation, Dual Energy for optimal image quality at lowest automatically provides a second contrast possible dose for each individual CT exam for the best possible diagnosis and added while considering tube voltage, tube diagnostic confidence so that each scan current, and contrast changes at different *syngo.via can be used as a stand-alone device can now become a Dual Energy scan. At voltages and attenuation. This allows you or together with a variety of syngo.via-based the same time, X-CARE protects individual to benefit from the industry’s widest tube software options, which are medical devices in their own rights. organs and the most radiation-sensitive voltage range – not only 140 kV for body regions – for example, female bariatric imaging but now, if necessary, **The information about this product is being breasts – by accurately and efficiently also down to 70 kV for new safety and provided for planning purposes. minimizing exposure while preserving image quality standards in pediatric The product is pending 510(k) review, and is image quality. imaging. not yet commercially available in the U.S. 9
  • 11. Split-Second Scanning How often has your daily practice been interrupted or delayed by fragile, sick, or traumatic patients who either cannot hold their breath or become impatient during regular scan procedures? Finding a solution to these hindrances is what has motivated us to design the world’s fastest CT, by utilizing Dual Source for Flash-like scan speeds of up to 458 mm/s. With Flash Spiral scanning, holding breath and motion lose their significance, making the SOMATOM Definition Flash the optimal patient- friendly CT. We introduce you to the new, cutting-edge of FAST CARE technology that raises the standard of your patient-centric productivity, e.g. through FAST Cardio Wizard, that breaks down the restrictions of previous CT scanning in cardiology. Today, split-second scanning is proving its value in actual practice. Emergency department trauma scans of an entire body in less than five seconds with dose usually under 5 mSv have also been made possible by the Flash’s speed. Now, with the help of the FAST Spine feature, making the preparation of complex vertebrae and disc reconstructions a matter of one click and 30 seconds, we take trauma imaging and neurological CT examinations to the next efficiency level for earlier and more accurately targeted treatment. 11
  • 12. Introduction Split-Second Scanning < 1 sec Body imaging in adult and Definition Flash with FAST CARE now pediatric patients offers Siemens’ unique FAST (Fully Assisting Scanner Technologies) platform Scanning an entire thorax in only to support you in finding and applying the 0.6 seconds for motion-artifact-free ideal settings for every individual studies that revolutionizes triple-rule-out examination to get to a safe, sound, and Tube 1 Tube 2 Vol protocols. The scan speed is fast enough sustainable diagnosis. Sub-second thorax scan for triple-rule-out and a dose to image the thorax without any breath below 5 mSv. hold and also produces crystal clear Cardiac imaging in a quarter imaging of the coronary arteries, thus of a heartbeat < 1 sec routinely enabling sub-second triple-rule- out with less than 5 mSv dose. The system’s unique split-second scanning capability allows scanning the heart in Bringing this scan speed to imaging only 250 ms, a quarter of a heartbeat. children makes sedation a thing of the Together with its highest temporal past. Now Flash Spiral scans are resolution of 75 ms, available in all cardiac consistently fast enough to produce sharp scan modes, it freezes any cardiac motion Tube 1 Tube 2 Vol pediatric images without sedation. This safely, irrespective of the heart rate. Sub-second pediatric scan without the need for sedation shortens prep time, eliminates repeating or anesthesia. scans due to motion, and reduces risk as Fastest scanning preparation well as anxiety. < 4 sec The challenge for each CT scan is to find Fastest emergency CT and apply the ideal settings for every individual patient, but at the same time For several years now, CT has been the achieve a high degree of reproducibility. ideal modality for trauma cases. However, Now, with FAST, scan and recon planning in the most severe cases the time required can become as fast and easy as just to produce useful images often placed the one click. Tube 1 Tube 2 Vol patient at risk. With Flash speed, scan time Whole body imaging in less than 4 seconds without is no longer an issue. The new SOMATOM motion artifacts. 12 Split-second scanning
  • 13. Automated scan and recon possible. FAST Cardio Wizard helps you planning achieve high-quality clinical outcomes in every situation. Flash Spiral scanning – Decisive for the ideal settings for scan, reconstruction, and image evaluation are Ready for review in one click no breath hold required the organs and body regions. Based on the respective organ, the chosen examination FAST Spine, another prominent feature Sharp coronaries at all heart rates type, and, at the end, also expected of the FAST technology, enhances rapid – even without beta-blockers images, in-depth knowledge of the trauma and neuro imaging, saving up to appropriate system settings is normally 30 minutes with a single click compared Pediatric scans without sedation required. Imagine the time the system to conventional workflows. Again easing, can save you by automatically planning accelerating, and standardizing the Whole body trauma scan < 4 sec the subsequent reconstruction fields in workflow in CT scanning. a whole body trauma. The SOMATOM Both guided and standardized Definition Flash with FAST and syngo.via syngo.via-based diagnosis cardiac workflow now automatically assist you in solving this challenge, making possible even Let us look at only one example of more shorter time to diagnosis and more than 17 functions that syngo.via, the Accurate spine recons with interaction with patients. outstanding multimodality imaging just a single click platform, performs: a triple-rule-out All heart rates, all patients assessment in less than four minutes Immediate, organ-based scan and automatically (at no click), coronal Not only does the selection of the and sagittal images for your referring planning appropriate scan mode for imaging every physicians located anywhere in your cardiac patient demand expertise, but also clinical network. The reading physician the preparation for image evaluation is can immediately start with the evaluation anything but trivial. It is important that of the case without wasting efforts in case you feel safe in having done everything in preparation. order to achieve the best clinical outcome 13
  • 14. How it works Flash Spiral Even the most advanced single-source CTs The SOMATOM Definition Flash guarantees are limited in their scan speed by the fast and accurate ED imaging by putting maximum table feed that can be used and you in the position to achieve earlier and still allow the acquisition of contiguous more accurately targeted treatment data. The SOMATOM Definition Flash decisions that positively affect the patients breaks through this barrier primarily by 30-day adverse event rate and reduce simultaneously integrating data from a repeated visits.(2) second source during the scan. By combining this Dual Source technology Revolutionizing the with fastest available hardware triple-rule-out components, including a gantry that rotates at 0.28 seconds, a patient table In case of acute chest pain, scanning that can handle immense table feeds, and with the SOMATOM Definition Flash ultra-fast data transmission technology, significantly saves time because it is now makes possible the fastest scan mode in possible to assess pulmonary arteries, CT history. The result is an unprecedented coronary arteries, and the aorta in a single scan speed of up to 458 mm/s, fast split-second scan. Scientific validation in enough to scan an entire adult patient large cohorts demonstrate impressive in less than four 4 seconds. results. Due to the SOMATOM Definition Flash’s split-second scanning capabilities Increased patient friendliness physicians obtain “motion-artifact-free and accurate visualization” in these Patients who cannot hold their breath or challenging examinations “at a very low suffer from shortness of breath, patients radiation exposure.”(2) Mean scan times are Single-source CT requires slower table feeds to prevent who are restless or impatient, who are 0.7 seconds while a radiation dose of only gaps in the acquired volume (bottom). uncooperative, obese patients or young 4.1 mSv or less is applied. Researchers find children, are no longer a problem. Due to that the Flash Spiral technology “has the its unprecedented scan speed, the Flash potential to revolutionize triple-rule-out Source Spiral mode even stops motion entirely, protocols.”(1) 1: Barns E. et al, High-pitch DSCT offers speedy images; preventing image artifacts that might www.AuntMinnie.com, Nov 30, 2009. obscure image quality and affect your 2: Press release, Andrew Stewart, Radiology Manager, sound diagnosis.(1) St George’s Hospital, UK, published online, Jan 1, 2010. 14 Split-second scanning
  • 15. Barrier-free pediatric Avoiding repetition of scans imaging Another and widely underestimated Bringing this scan speed to imaging risk factor is eliminated as well by the children, the most delicate patient group, Flash Spiral technology: the unnecessary opens new possibilities by eliminating repetition of scans in young children due the need for sedation or anesthesia. to failed sedation, which unfortunately Researchers state that mean examination is the case in 29% of conventional times of only 0.49 seconds provide examinations, shown in a large trial.(2) highest image quality making sedation or controlled ventilation unnecessary, Sub-second scanning of up to 458 mm, Tube 1 Tube 2 while maintaining low radiation dose with a wide 78 cm bore for unrestricted values.(1) access to your most sensitive patients, makes a true difference in your pediatric Dual Source CT combines the data from two detectors for Being independent of this time-consuming scanning, from saving prep time and faster table feeds above a pitch of three for revolutionary and potentially dangerous procedure can staff, repeating scans due to motion, to triple-rule-out scanning and barrier-free pediatric imaging save you up to 80 minutes of preparation reducing risk as well as anxiety. Yet without sedation. time and involves less personnel. another proof for the SOMATOM Definition A positive economic side effect of the Flash being the healthiest CT available. SOMATOM Definition Flash for pediatric imaging is that you can do without the expensive services of the anesthetist. Source 1: Lell MM. et al, Invest Radiol. Sep 17, 2010. [Epub ahead of print]. 2: Malviya S. et al, British Journal of Anesthesia 84 (6): 743–8 (2000). 15
  • 16. How it works FAST Cardio Wizard All heart rates, all patients Guidance for high-quality clinical outcomes in every The SOMATOM Definition Flash is the fastest cardiac scanner in the industry, situation offering a true single-segment temporal resolution of 75 ms. Its Flash Spiral But cardiac CT examinations are also acquires the entire heart in around among the most sophisticated and 250 ms – within a single heartbeat. demanding procedures in CT, requiring It alternatively enables robust diagnostic careful preparation and a high degree of outcomes, even in the presence of high expertise. All the more, it is important that heart rates and arrhythmia, and has been the user feels sure that he has done repeatedly proven by a wide range of everything correctly in order to achieve clinical studies. This permits imaging the the best clinical outcome possible and to heart without the clinical, workflow, and avoid any unnecessary radiation of the financial aspects of utilizing beta-blockers patient. Additionally, it allows you to when using the Flash cardio sequence. define your individual institutional guided The realities of healthcare today often do cardiac workflow for standardization to not permit the interruptions in workflow, guarantee continuous high-quality clinical The modifiable text in the guided workflow allows you to longer patient preparation times, and use outcomes in every situation. define your standards and quality goals that users have to of personnel required by the use of beta- follow in order to always achieve an optimal cardiac scan. blockers. Not to mention the fact that Therefore, the new SOMATOM Definition some patients should not receive beta- Flash offers the FAST Cardio Wizard, blockers, such as in certain cases of explaining to the operator on a step-by- pulmonary disease. All this makes the step basis what needs to be done to Flash Cardio Sequence the industry’s most achieve an optimal cardiac scan, either in versatile low dose mode for cardiac real-time when preparing a scan or for imaging. training purposes. 16 Split-second scanning
  • 17. How it works FAST Planning Fastest emergency CT through FAST Planning uses defined automated planning anatomical landmarks to set the correct recon ranges within a large In time-critical emergency situations, scan field of view – as in trauma long scan ranges involving different body imaging – for faster results when regions and organs are common. The every second counts. planning of the scan and reconstruction field of view is prone to error and eat up precious time to diagnosis. FAST Planning focuses explicitly on this critical part of the scan process. Based on the topogram, FAST Planning assists the scan and reconstruction planning to provide an easier, faster, and standardized workflow in CT scanning. The selection of the anatomical region of interest (ROI) from a list automatically defines prospectively the scan and reconstruction ranges. The scan ROIs are automatically detected based on the characteristics of the organ that is to be scanned. In addition, the corresponding scan ranges are proposed in the topogram as well. In the case of head scans, the iso-center is automatically adapted according to the position of the patient’s head to prevent cutting off important information during the emergency examination. 17
  • 18. syngo.via Additional Benefits with syngo.via Make lifesaving decisions, when every second counts … Acute Care imaging often requires multiple clinical disciplines such as radiologists, cardiologists, neurologists, and trauma surgeons to review images to develop a structured and prioritized treatment plan. syngo.via’s unique information sharing makes it easy to involve all required disciplines into the therapeutic decision-making process. The client/server architecture allows you to access the data independently with up to five users for fast parallel reading. It allows clinicians to review the same images on their individual workplaces For example, it enables you to conduct Dual-monitor layout for instant emergency reading to discuss decisions remotely. a thorough analysis of the major blood process. This is the first view directly after loading vessels of the body with their curved the patient. The Acute Care Engine helps you in more multi-planar reformations (MPR) and demanding cases by automatically adding appropriate display layouts the moment incremental information for your diagnosis you open the case. Additionally, it and supports you with a powerful set of automatically provides you with coronal, intelligent tools. sagittal reconstructions of the patient’s data that can be displayed in the entire clinical network such as the ICU, the PACS workplace, the OR, or when you discuss the patient’s diagnosis in your office. 18 Split-second scanning
  • 19. Rule out coronary heart The syngo.CT Cardiac Function – as part of disease in under a minute the CT Cardio-Vascular Engine – allows you to read and diagnose CT angiography The moment you open a cardiac case, the images of the left side of the heart for the Automated Case Preparation has already evaluation of ischemia or cardiomyopathy. preprocessed the images and displays them in your appropriate layout together Additionally, the application can evaluate with the adequate evaluation tools. This the late or early myocardial enhancement means that you can immediately start of single energetic CT data which is evaluating the coronary vessels, the displayed as a color overlay. The Cardio- functional parameters, and the prepared Vascular Engine’s Pro level provides right calcium score. ventricular volumetric analysis,* which may have prognostic value for congestive The comprehensive layout for display of heart failure, chronic pulmonary disease, multiple CPRs permits the review of the and pulmonary emboli. coronary tree at the blink of an eye. All your findings and key images are collected in the Findings Navigator on-the-fly as you Single-click stenosis aneurysm measurement. read the case. Your result: rule-out and Three reference lines are already predefined. reporting of coronary artery disease in less than a minute. *The CT Acute Care Engine is pending 510(k) review and is not yet commercially available in the U.S. 19
  • 20. Split-second scanning Clinical Results Motion-free emergency room trauma Flash Spiral scans of an entire body in Split-second scanning of the human heart with Flash less than four seconds with dose usually under 5 mSv. Spiral in only 250 ms for motion-free and sharp coronary arteries due to unmatched 75 ms temporal resolution. 20 Split-second scanning
  • 21. Organ-based setting of scan and recon ranges with FAST Planning for a fast and more Restless children or patients who cannot hold their breath standardized workflow at the scanner. FAST Spine allows the preparation of anatomically no longer cause time-consuming interruptions. aligned spine recons with just a single click. 21
  • 22. 22 Defining low dose CT
  • 23. Defining Low Dose CT Applying the lowest radiation dose possible is of the utmost importance for both you and, of course, your patients. Therefore you always want to be assured that you have taken every means available to protect your patient from unnecessary radiation. This desire lies at the heart of our CARE (Combined Applications to Reduce Exposure) research and development philosophy. Consequently, with Siemens’ continuing effort to achieve highest dose protection, the new SOMATOM Definition Flash now combines all features to reduce radiation as low as possible: next to its already outstanding dose protection portfolio from the initial product generation, it now adds a wide range of new and improved dose reduction features. CARE kV, for instance, is the industry’s first tool for automatically solving the complex equation for optimal image quality at lowest possible dose for each individual CT exam while considering tube voltage, tube current, and contrast changes at different voltages and attenuation. This allows you to benefit from the industry’s widest tube voltage range – not only 140 kV for bariatric imaging but now, if necessary, also down to 70 kV where the Definition Flash sets new standards in pediatric safety. Add the first, raw-data-based iterative reconstruction SAFIRE* and define low dose for all body regions to take best care of your patients well-being. *The information about this product is being provided for planning purposes. The product is pending 510(k) review, and is not yet commercially available in the U.S. 23
  • 24. Introduction Defining Low Dose CT Sub-mSv heart – CARE kV – solving a complex the ultimate CARE feature equation Discussions regarding dose in cardiac But CT scanning is not only about adapting scanning have changed because dose mAs values: the right kV settings play an values down to under 1 mSv are so equal, if not more important, role in frequent that Sub-mSv heart can be choosing the right parameter to achieve considered routine for Siemens SOMATOM optimal clinical outcome at lowest Definition Flash owners. Such low routine possible dose. Siemens’ unique CARE kV values have opened realistic discussions now addresses this consideration, and about the use of Flash Spiral for early supports the user in exploiting the detection of coronary artery disease. remaining dose-saving capabilities in kV adaptation. Optimizing tube current and voltage < 1 mSv As early as 1994, Siemens introduced the first versions of CARE Dose4D to actively Flash Spiral allows for ultra-fast spiral acquisition at modulate the applied power for scans 75 ms temporal resolution with scan speed of up to depending on the patient’s anatomy. With 458 mm/s for maximum dose efficiency in your daily FAST CARE the configuration options have clinical practice. now been made more flexible and can be perfectly adjusted for every patient so that you can achieve lowest possible dose at optimal image quality in every examination. 24 Defining low dose CT
  • 25. Taking care of children Preventing unnecessary radiation The Flash Spiral scan has proven to be Routine Sub-mSv cardiac CT a robust method for scanning children and SOMATOM Definition Flash eliminates infants without sedation while providing unnecessary pre- and post-spiral opens the door to early detection high image quality at lowest possible over-radiation with its two Adaptive Dose dose.(1) Shields offering dose reductions up to Lowest dose in all organs 25%. It also protects dose-sensitive body With CARE Child, offering the 70 kV regions, such as the female breast, Adaptive Dose Shields eliminate STRATON tube redesign together with a set eyeballs, the thyroid glands, or the unnecessary dose of dedicated pediatric scan protocols, the gonads, through X-CARE with possible new SOMATOM Definition Flash offers a dose reductions up to 40% while Protect radiation-sensitive organs unique solution to provide even healthier preserving the image quality. scanning for your youngest patients. Dose reductions in a wide range With CARE kV you now benefit from the Iterative reconstruction of protocols with iterative industry’s widest tube voltage range – down to 70 kV where the new SOMATOM Siemens now introduces SAFIRE*, the first reconstruction Definition Flash sets new standards in low raw-data-based iterative reconstruction, dose pediatric imaging. that is a unique approach allowing for up to 60% additional dose savings. *The information about this product is being Source provided for planning purposes. 1: Lell MM. et al, Invest Radiol. Sep 17, 2010. The product is pending 510(k) review, and is [Epub ahead of print]. not yet commercially available in the U.S. 25
  • 26. How it works Sub-mSv Heart 20 mSv Dose down to below 1 mSv Low dose cardiac for all heart rates Single source With the SOMATOM Definition Flash, 15 mSv discussions regarding high dose versus When fully flexible X-ray pulsing meets low dose cardiac scanning will change, 75 ms of temporal resolution, the result 10 mSv because, even under unfavorable is the Flash Cardio Sequence, the most conditions, the patient exposure with the versatile low dose cardio scan mode on SOMATOM Definition Flash is less than the market. 5 mSv what is required for diagnostic cardiac cath. Many clinical trials demonstrate that The intelligently triggered sequence shuts 1 mSv high dose cardiac CT no longer exists with off radiation in the systolic phase when Siemens equipment.(1, 2, 3) With Flash Spiral, not required and dynamically reacts to Single-source cardiac spiral scanning requires dose values down to under 1 mSv – irregularities during the ECG trace. The overlapping data acquisition, resulting in relatively high especially important for the most dose- real-time ECG monitoring reacts instantly patient exposure (top). sensitive patients – are so frequent they and stops the scan until the heart rate can be considered routine. becomes stable again. This arrhythmia compensation method allows for high 5 mSv Such low values can open realistic dose savings and an increased robustness discussions about the use of CTA for early of the scan. 4 mSv detection of coronary artery disease, 3 mSv taking advantage of its ability to scan the For the first time, a step-and-shoot mode entire heart in only 250 ms – a quarter is robust and fast enough to freeze the 2 mSv of a heartbeat. And, for less favorable heart and visualize the coronary arteries conditions, such as high heart rate or even at high heart rates, thus allowing 1 mSv arrhythmia, the Flash Cardio Sequence even low dose cardiac CT without the Flash with its automated arrhythmia need for beta-blockers. compensation still allows dose below diagnostic cath. Its unique dual pulsing Source Flash Spiral with Dual Source CT allows for ultra-fast spiral even calculates the heart’s ejection 1: Leschka S. et al, Eur Radiol. 2009 Dec; 19(12): 2896–903. acquisition for maximum dose efficiency in your daily fraction. 2: Lell M. et al, Eur Radiol. 2009 Nov; 19(11): 2576–83. clinical practice (bottom). 3: Achenbach S. et al, Eur Heart J. 2010 Feb; 31(3): 340–6. 26 Defining low dose CT
  • 27. How it works CARE kV and CARE Child Real-time dose modulation CARE kV, an extension of CARE Dose4D, can now automatically suggest kV and CARE Dose4D aims to regulate the effective mAs to optimize the contrast-to- mAs so that image quality is uniform noise-ratio (CNR) of the image while across the whole scan range. CARE Dose limiting the applied dose. The system’s Configurator provides the user the ability proposal is based on the attenuation as to select reference curves for each body measured in the topogram and the user- region and for each body habitus defined acquisition type (non-contrast, individually. With the new SOMATOM bone, soft tissue, vascular). The system Definition Flash with FAST CARE the also identifies bariatric patients and configuration options have now been consequently sets the parameters to make made even more flexible for perfect full use of the system’s reserves. CARE kV 70 kV 80 kV adjustment for every patient. is, of course, fully customizable, meaning 100 kV that the user can choose the degree of 120 kV Solving a complex equation system assistance between none, semi, 140 kV and full. The dose saving and image quality potential of the right kV settings play an Taking care of children equal, if not more important, role to achieve optimal clinical outcomes. But With the new improved STRATON tube changing kV values always comes along the voltage range is extended from 80 with the need to adapt all other values down to 70 kV where it sets new standards according to the respective patient and in low dose pediatric imaging with CARE the proposed examination. Unfortunately, Child. The new 70 kV scan mode further up to now this had to be done manually reduces the dose to small pediatric or Example: For a vessel examination of a small and required a lot of expertise. These neonate patients. These dedicated patient, CARE kV proposes scanning with 70 kV dependencies are described in a complex pediatric scan modes take care of the well- and sets the other values for optimal image quality physical equation, so that often the full being of our youngest patients. Overall, at lowest dose accordingly. potential for dose reduction remained with these features, an additional dose untapped with 120 kV being used in reduction of up to 60% is possible and almost every adult patient. easy to achieve in clinical practice. 27
  • 28. How it works X-CARE X-ray low Additional dose reduction of up to 40% Siemens has recognized the importance of dose-sensitive scanning, especially for female patients, but also when directly radiating the eye lens or the thyroid gland. A simple but effective approach to lower dose for the most dose-sensitive body regions is partial CT scanning, that has been integrated into dedicated protocols X-ray on of the SOMATOM Definition Flash. It protects these areas from direct X-ray Conventional scanning X-CARE nearly switches the exposure by nearly switching the X-ray applies radiation permanently tube current off within a tube off for a certain range of projections, during the full rotation, thus certain range of projections, while automatically adjusting tube resulting in direct exposure of minimizing direct exposure currents for the remaining projections radiation-sensitive organs, for highly dose-sensitive to prevent deteriorating image quality. for example for the breasts. body regions. The result with X-CARE is reduced sensitive-area exposure up to 40% without loss of image quality. 28 Defining low dose CT
  • 29. How it works SAFIRE Iterative Reconstruction with homologous reference data. This Standard Filtered SAFIRE* procedure can be regarded as validating Back Projection SAFIRE* – Sinogram Affirmed Iterative (or affirming) the current images. Reconstruction – for the first time allows to utilize the full dose-saving potential An updated image is then again recon- of the iterative reconstruction in clinical structed, using the detected deviation practice. Now, raw-data information information. In each iteration a dynamic (which is visualized in the so-called raw-data-based noise model is applied Raw data sinogram) is actually being utilized in that allows for reduction of image noise recon Raw data Image data Image the image improvement process. without noticeable loss of sharpness. This recon recon correction optimization process thus makes even After the initial reconstruction using the better use of the diagnostic information weighted filtered back projection (WFBP) contained in the raw data. Using multiple the first iterative reconstruction loop is iterations, geometrical imperfections of performed. The CT images are retrans- the WFBP are corrected in addition to ferred to raw data which models all incrementally reducing image noise. relevant geometrical properties of the CT scanner. This step reproduces CT raw data With this, SAFIRE* allows for a radiation Ultra-fast reconstruction More powerful dose like a real scanner does. By comparing dose reduction of up to 60% or improved without iterations reduction than image- this synthetic raw data with the acquired image quality in regards to contrast, Well-established image based methods data, differences are identified. A further sharpness, and noise. impression Well-established image iteration loop compares the images Limited dose reduction impression Superior image quality Fast reconstruction in image and raw-data space and improved workflow with variable settings *The information about this product is being provided for planning purposes. The product is pending 510(k) review, and is not yet commercially available in the U.S. 29
  • 30. syngo.via Additional benefits with syngo.via CT Acute Care Engine disease, aortic dissection, or pulmonary embolism. syngo.CT Coronary Analysis, Make lifesaving decisions, when every as a part of the CT Acute Care Engine, second counts … evaluates the coronary status and quantifies stenoses in less than one CT is the modality of choice when it minute through Single Click Stenosis comes to diagnostic imaging in acute care measurement. syngo.CT’s Cardiac Function situations, whether it is for a triple-rule-out is also able to evaluate whether the of acute chest pain, for stroke assessment, myocardial function has already been polytrauma, or for acute abdominal pain. affected by an infarction, while syngo.CT The CT Acute Care Engine provides clinical Vascular Analysis with VesselSURF is the functionality that delivers decisive results perfect tool to assess the extent of an Tube 1 Tube 2 for all of these challenging indications. aortic dissection, or to evaluate a syngo.via’s workflow is another remarkable pulmonary embolism. feature, as the Direct Image Transfer, Dual Source CT combines the data from two detectors Study Split for parallel assessment with Flash Spiral scanning of the for faster table feeds above a pitch of three. up to five parallel readers, together with entire thorax below 4 mSv Automated Case Preparation, make the CT Acute Care Engine the zero-delay The prospectively triggered Flash Spiral diagnostic tool. Above all, speed and scan perfectly meets the need for patients dependability add confidence for critical who present with acute chest pain to decisions made against the clock. exclude coronary artery disease, pulmonary embolism, and aortic The CT Acute Care Engine* provides dissection. The average dose for this high comprehensive image-processing speed examination is 1.6 mSv for patients functionality for triple-rule-out of acute who can be scanned with 100 kV protocols chest pain caused by coronary heart and 3.2 mSv for patients who can be * The CT Acute Care Engine is pending 510(k) review and is not yet scanned with 120 kV protocols. commercially available in the U.S. 30 Defining low dose CT
  • 31. The prospectively triggered high-pitch Flash Spiral scan mode for triple-rule-out allows motion-artifact-free and accurate visualization of the entire thoracic vessels, including the aorta, pulmonary, and coronary arteries at dose levels, before unseen, of below 4 mSv. syngo.via automatically displays the acquired data in the appropriate layout and has preprocessed it according to the triple-rule-out specific (disease-oriented) workflow for a quick rule-out in less than four minutes. Triple-rule-out of coronary artery disease, aortic dissection, or pulmonary embolism in less than four minutes. 31
  • 32. Defining low dose CT Clinical Results CARE Child, with the 70 kV STRATON tube, defines new low dose Sub-mSv heart, the ultimate CARE feature. Dose values down to under safety and image quality standards in pediatric imaging. 1 mSv are so frequent that Sub-mSv heart can be considered routine for SOMATOM Definition Flash users. 32 Defining low dose CT
  • 33. Thoracoabdominal aorta examination, including the coronary arteries, with 1.9 mSv low dose Flash Spiral scan together with iterative reconstruction of dose below 5 mSv, automatically preprocessed in syngo.via, showing aortic a newborn after perinatal complications. insufficiency. 33
  • 34. 34 Dual Source DE for all patients
  • 35. Dual Source DE for all Patients It has always been a CT goal to collect as much information as possible in order to differentiate tissues. With Dual Energy scanning, the SOMATOM Definition and SOMATOM Definition Flash open the door to a new world of characterization, visualizing the chemical composition of material. The idea of Dual Energy is not new to the CT community. Earlier approaches, including two subsequent scans at different tube voltages or two subsequent scans at the same position, failed to seamlessly align the imaged anatomy and to capture the same phase of contrast enhancement. Dual Energy was first successfully introduced into clinical practice with Dual Source CT, i.e. two X-ray tubes and two UFC (Ultra-Fast Ceramic) detectors mounted at 90 degrees from each other and perfectly synchronized during scans. And, to date, Dual Source remains the only modality that enables the usage of Dual Energy in daily practice at a dose comparable to a conventional 120 kV scan and with optimum spectra separation for highest value DE information. With 12 FDA-cleared applications and more than 700 Dual Source CTs installed, the number of Dual Energy scans has skyrocketed worldwide and is expected to continue increasing at an even higher rate. Dual Energy with Dual Source CT adds the decisive diagnostic confidence for sustainable and sound treatment decisions – it is the advantage that proves itself over and over in daily practice. 35
  • 36. Introduction Dual Source DE for all Patients Selective Dual Source Dual Energy Dose-neutral every day Photon Shield setting the standards Dual Energy imaging Dual Source Dual Energy (DE) CT An additional benefit is the fact that all acquisition provides an expanded set of renowned dose-saving techniques, such diagnostic capabilities and alters CT as CARE Dose4D, Adaptive Dose Shield, imaging in significant ways. Clinicians in and X-CARE, can be applied to effectively 700 international institutions, working achieve dose-neutral Dual Energy imaging with SOMATOM Definition and Definition for everyday usage without a dose Flash, are setting the technological and penalty compared to a conventional 120 kV clinical benchmark in Dual Energy scan.(1, 2, 3) Moreover, with Dual Source imaging. Dual Energy you can now get motion-free 80 kV 140 kV diagnostic images with a temporal Attenuation B Attenuation A Most important and most obvious with the resolution of down to 75 ms in Cardiac Dual Source approach: detector units can Dual Energy imaging. Always a dose-neutral operate at different tube potentials during second contrast. the synchronous CT acquisition. This avoids spectral contamination or waste of applied dose occurring during kV-switching time intervals. Furthermore, the Dual Source approach allows the introduction of X-ray filters such as the Selective Photon Shield for even further spectral separation. Source 1: Schenzle JC. et al, Radiol. 2010 Jun; 45(6): 347–53. 2: Graser A. et al, Invest Radiol. 2010 Jul; 45(7): 399–405. 3: Thomas C. et al, Invest Radiol. 2010 Jul; 45(7): 393–8. 36 Dual Source DE for all patients
  • 37. Dual Energy for all patients Already clinical routine Dual Source DE brings new levels of More than 130 peer-reviewed publications Always second contrast at no dose contrast, for instance with Optimum for our 12 FDA-approved DE applications Contrast, to all images over a broad range provide evidence and identify the penalty of routine examinations. It offers improvements in clinical outcome as a significant patient benefit improving result of their implementation. 800,000 Wide range of 12 FDA-cleared diagnostic outcomes through improved successful DE examinations have already applications lesion detection, removal of bone and helped to detect pulmonary embolisms in plaque, improved visualization of metal lung vessels, to directly remove bone and Optimum Contrast in every image prostheses, chemical analysis of normal plaque in angiographies, to characterize and pathologic tissue, and iodine mapping. renal calculi, or to allow for enhanced Improved visualization of metal It may grant the decisive diagnostic lesion conspicuity through Optimum information for a safe, sound, and Contrast, or simply to speed up workflow prostheses sustainable diagnosis and treatment through Virtual Non-Contrast Imaging. planning in any of the patients entrusted 75 ms high temporal resolution DE to you. freezing any cardiac motion syngo.via automatic virtual non- contrast bone and hard plaque removal syngo.via auto-preprocessing for immediate sagittal/coronal display 37
  • 38. How it works Single-Source CT Dual Source Dual Energy (DE) The X-ray tube’s kilo voltage (kV) Benefits of determines the average energy level of Dual Source scanning the X-ray beam. Changing the kV setting 120 kV results in an alteration of photon energy Using the two Z-Sharp STRATON tubes, and a changed attenuation of the Dual Source data acquisition allows for materials scanned. For instance, scanning at least 1,152 projections per rotation Single-source CT only provides one energy level for an object with 80 kV results in a different and spectrum. This provides homogeneous morphology imaging. attenuation than with 140 kV. In addition, image quality over the entire FOV. this attenuation depends also on the type In spiral mode the same slice is acquired of tissue scanned. While the CT value for within the same time interval for both iodine is highest at the low-energy scans, spectra, so the reconstructed images show it can be less than half in the high-energy no time offset. The fast gantry rotation of Dual Source CT scans. The attenuation of bones, on the 0.28 seconds, with only 0.24 ms sampling other hand, changes much less when time, minimizes motion artifacts, while all exposed to low-energy scans compared renown dose-saving techniques can be to high-energy voltage examinations. applied, such as CARE Dose4D, Adaptive Dose Shield, and X-CARE. In addition, The material-specific difference in IRIS and SAFIRE* iterative reconstruction attenuation enables an easy classification techniques can be applied. of the elementary chemical composition of the scanned tissue. In addition, a fused Monoenergetic imaging image is provided for initial diagnosis. Using the SOMATOM Definition Flash also allows obtaining monoenergetic CT images. These are similar to images acquired with a synchrotron X-ray beam 80 kV 140 kV Attenuation B Attenuation A of single photon energy. The equivalent *The information about this product is being photon energy between 40 keV and provided for planning purposes. 190 keV (151 steps) can be optimized Two X-ray sources set to different kV levels simultaneously The product is pending 510(k) review, and interactively to provide best contrast for acquire two data sets at different attenuation levels. is not yet commercially available in the U.S. the lesion of interest. 38 Dual Source DE for all patients
  • 39. How it works Selective Photon Shield Without Selective Photon Shield number of quanta 80 kV 140 kV overlap Eliminating unnecessary Better dose efficiency radiation While Dual Source technology has already An important factor in making dose overcome this limitation, the Selective neutrality viable is the development of Photon Shield further increases dose the Selective Photon Shield that blocks efficiency by filtering out unnecessary unnecessary photons of the X-ray energy photons of the high-energy X-ray tube. spectrum. The result is a much better The remaining photon spectrum is photon energy separation of the 80 kV and 140 kV therefore better focused and more clearly images, as the second detector is 25% separated from the photons emitted by With Selective Photon Shield larger than previously. the low-energy tube. The result is a much number of quanta better separation of the 80/140 kV images, 80 kV In effect, the Selective Photon Shield increasing bone-iodine differentiation 140 kV assures dose neutrality for single-dose by up to 80% while reducing overall dose. overlap Dual Energy by avoiding unnecessary Therefore, the high-quality 80/140 kV exposure. Thus it makes Dual Energy as mode is ideal for the head and extremities, dose-efficient as conventional 120 kV especially CT angiographies. scans. So all the diagnostic advantages of Dual Energy imaging are now available The spectral separation through the with the same dose as a single energy Selective Photon Shield on the other hand, scan. opens the possibility to use 100/140 kV imaging with still 30% better bone-iodine contrast and more power reserves for photon energy cardio, abdomen, pelvis, and larger patients in general, making Dual Energy a The Selective Photon Shield increases energy clinical application for all your patients. separation and reduces unnecessary dose by blocking low-energy photons out of the high-energy X-ray tube’s spectrum. This results in optimal information quality and dose neutrality compared to a conventional 120 kV scan. 39
  • 40. How it works Optimum Contrast Maximizing anatomic the detail from the 140 kV images in non- information enhanced areas, an optimized image can be automatically calculated. It is especially Dual Energy can be used to enhance the helpful in enhancing conspicuity of lesions iodine signal. It is well-known that the for a safe, sound, and sustainable therapy iodine signal is potentiated at low tube planning that may improve outcome, cost energies (80 and 100 kV), yet lower tube effectiveness, and patient comfort. energies are not employed in general CT scanning because of increased noise. syngo.via enhanced This is what builds the foundation of Dual DE imaging Energy Optimum Contrast. 80 kV scan 140 kV scan syngo.via dose not only provides you Focus: iodine, high Focus: soft tissue Optimum Contrast with the result images, for instance of contrast and low image noise Optimum Contrast, in all standard views The images obtained at 80 and 140 kV such as coronal, sagittal, and axial. It also automatically exploit the spectral behavior automatically removes bone and hard of certain materials or tissues in syngo.via. plaque in the major vessels for a easier Additionally, average images can be assessment of the true lumen. calculated to provide a ”normal” CT image, because the 140 kV images lack contrast, With syngo.via clients, your results, such while the 80 kV images are naturally more as Dual Energy Brain Hemorrhage images, noisy. can be instantaneously displayed in the OR* or the angio suite. By adding more of the contrast information from the 80 kV images in Best of both worlds to maximize areas of iodine enhancement, and more of anatomic information: less noise and more contrast than standard *Usage of syngo.via for an emergency case CT images. requires customer to provide respective emergency measures in case of non-availability of system or network. 40 Dual Source DE for all patients
  • 41. How it works High Temporal Resolution DE Dual Energy Flash Cardio Dual Energy Heart Perfused Blood Volume Another CT first: the SOMATOM Definition Flash allows scanning the entire heart, With its high temporal resolution, Dual and then evaluating the coronaries with a Source CT has greatly improved coronary full temporal resolution of 75 ms as well CT angiography, because it is less sensitive as, in a second reconstruction, visualizing to high heart rates or arrhythmia than perfusion defects in the myocardium, other types of scanners. With Dual thus combining the maximum speed of Energy CT, it is now possible to highlight 80 kV 140 kV Dual Source CT with Dual Energy imaging iodine content to visualize organ Attenuation B Attenuation A in a single scan. This has been made perfusion. Prospectively triggered possible with our latest reconstruction sequence or retrospectively gated spiral technology, that allows achieving Dual acquisition modes are available for first Source temporal resolution from image pass or late enhancement Dual Energy components acquired at different energy myocardial perfusion studies. The levels. The result is the ability to obtain corresponding syngo Dual Energy Heart diagnostic Dual Energy CT images without PBV software color-codes myocardial the use of beta-blockers. perfusion, so that both coronary artery 140 ms reconstruction 75 ms high temporal morphology and myocardial perfusion (low spatial frequencies) resolution reconstruction can be assessed in a single CT scan. (high spatial frequencies) Result: high temporal resolution DE High 75 ms temporal resolution Dual Energy freezes even cardiac motion and allows color-coded perfused myocardial blood pool evaluation, for example for patients suspected of having an acute myocardial infarction. 41
  • 42. syngo.via Additional Benefits with syngo.via Speed in routine – power in challenging cases The new CT Cardio-Vascular Engine offers excellent functionality for the automatic anatomical evaluation, quantification, and functional assessment of CT angiography images of the heart or the peripheral vessels, while allowing manual interaction for challenging cases at any time. Before you open a case, the Automated Case Preparation has already pre- processed the images, including the Dual Energy direct bone and hard plaque removal and displays them in your appropriate layout together with the adequate evaluation tools. You can immediately start evaluating syngo.via showing a severely calcified the major blood vessels of the body with thoracic aorta in which Dual Energy their curved multi-planar reformations direct bone and hard plaque removal was (MPR) and appropriate display layouts. automatically applied in the background – Additionally, it automatically provides you before you opened the case. A single with coronal, sagittal reconstructions of click on your patient in your private the patient’s data that can be displayed in Worklist opens the case the way it is the entire clinical network such as the ICU, displayed here. the PACS workplace, or when you discuss the patient’s diagnosis in your office. *Not commercially available in the US. 42 Dual Source DE for all patients
  • 43. From scan to diagnosis status of the vascular structures and in under ten minutes the brain tissue for these patients – from scanning to diagnosis in less than CT Neuro imaging is very often a matter ten minutes including Dual Energy data of life-and-death therapeutic decision- into the disease-oriented workflow for making. From infarctions caused by stroke seamless integration into your clinical and extensive bleeding, to subarachnoid practice. Using data delivered by the hemorrhage and a ruptured aneurysm – Adaptive 4D Spiral, perfusion assessment seeing them clearly is essential because of the brain can easily be integrated in the of the huge difference it makes in assessment. The CT Neuro Engine also determining treatment. The new CT Neuro helps identify fractures after an accident Engine provides tools and workflows that and, for instance, uncovers the potential help deliver a complete and accurate stenosis when looking at the vascularity of the neck. If a Dual Energy examination, such as a Dual Energy Brain Hemorrhage calculation was made, the data is automatically displayed together with all your other pre- processed data. So Dual Energy data, seamlessly integrated in syngo.via, may give you the decisive diagnostic information for taking sound, safe, and sustainable treatment decisions in any patient. 43
  • 44. Dual Source DE for all patie Clinical Results Single dose Dual Energy shows a lung perfusion defect in the right Dual Energy direct hard plaque and bone removal for immediate true lumen lower segment – unveiling the effect of pulmonary emboli. assessment. Automatically preprocessed in syngo.via with coronal, sagittal, and axial reformats for sound treatment decisions. 44 Dual Source DE for all patients
  • 45. nts Monoenergetic imaging, on the right, provides improved visualization of the Dual Energy Optimum Contrast (right) combines the advantages of low and high kV metal screws relative to the surrounding bone tissue. CT scans for enhanced lesion conspicuity in iodine-enhanced CT images. 45
  • 46. Customer Care Dedicated to Your Success Remain one step ahead and tap the Upgrades and migration: Services and support full potential of your Siemens CT system Evolve, Expand, Elevate with our customer care program, Life. Feel confident with our proactive As a worldwide innovation leader in Stay competitive with up-to-date systems service solutions medical imaging, Siemens has gained unmatched knowledge in Computed Due to increasing healthcare demands you High system availability, diagnostic Tomography. You can profit from excellent have to stay on the cutting edge to be confidence, and optimized workflow CT systems and innovative, flexible, and competitive. We will help you to keep your are crucial for the success of your comprehensive service solutions that solutions up-to-date and to keep pace with CT service. To meet your performance enable you to concentrate on what is the latest technological advancements expectations, we systematically focus most important for you: patient care. through the syngo Evolve program. syngo on being proactive. Based on real-time The customer care program, Life, is Evolve offers certainty in budget planning, system monitoring we detect system the unique solution from Siemens that feature enhancements for your CT, access errors and alert you before problems helps you to maximize the return on to new applications, and lower cost occur. The Siemens Guardian Program™ investment throughout the entire life upgrades for your CT system. helps to make unplanned downtime a cycle of your system. thing of the past. 46 Customer Care
  • 47. Education and training Information and communication Broaden your knowledge and expertise Be informed – get connected Know-how is the key to success. With our extensive portfolio of education and To ensure you are always up-to-date training programs you can deepen your on what is happening in the CT world, knowledge and clinical expertise. We we offer you a variety of information show you how to maximize the benefits services including easily accessible that can be achieved with our advanced information portals, monthly newsletters, technology. This will help you to optimize our customer magazine SOMATOM your workflows so you can offer an even Sessions, and the SOMATOM World higher quality of care for your patients. Summit, our scientific user conference. 47
  • 48. SOMATOM Definition Flash Configuration Overview SOMATOM Definition Flash with FAST CARE • All routine and advanced • High-speed whole-body coverage at Access to: applications for clinical practice highest spatial resolution • SAFIRE* – the first raw-data-based • Industry’s fastest Flash Spiral • Pediatric and bariatric CT imaging with iterative reconstruction scanning no patient exclusion • Full FAST functionality like FAST Planning • Full CARE functionality like CARE • Two Adaptive Dose Shields blocking and FAST Spine to raise patient-centric kV and CARE Child, including the clinically irrelevant dose in spiral scans productivity redesigned 70 kV STRATON tube • 3D-guided interventional CT • High-performance image • Ultra-long-range dynamic reconstruction system with imaging (up to 48 cm) for WorkStream 4D whole organ coverage • Industry’s highest – heart rate • Scanner-injector coupling including independent – temporal injector protocol management resolution of 75 ms for all heart rates in cardiovascular imaging • Latest syngo.via Engines with automated preprocessing tools for rapid, sound and • State-of-the-art cardiovascular sustainable diagnosis imaging • Dose-neutral Dual Energy imaging at • Industry’s widest range of kV high temporal resolution with 12 FDA- steps and strongest generator cleared applications power • Dynamic myocardial stress perfusion imaging *The information about this product is being provided for planning purposes. The product is pending 510(k) review, and For more details on FAST CARE benefits for your patients, please visit www.siemens.com/fastcare is not yet commercially available in the U.S. 48 Configuration overview
  • 49. Rotation time 0.28 s* Number of slices 2 x 128 Generator 200 kW (2 x 100 kW) kV steps 70, 80, 100, 120, 140 kV Isotropic resolution 0.33 mm Temporal resolution 75 ms*, heart-rate independent Max. scan speed 458 mm/s* with Flash Spiral Table load up to 300 kg/660 lbs* Gantry opening 78 cm *optional 49
  • 50. SOMATOM Definition Flash SOMATOM Definition Flash