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SUBSTANCE USE 
DISORDERS 
Jacqueline Corcoran, Ph.D. 
Virginia Commonwealth University 
School of Social Work
DSM 5 change 
Abuse and dependence subsumed into 
use disorder 
Severity: mild, medium, and severe
10 classes 
 alcohol 
 Amphetamines 
 cannabis 
 cocaine 
 hallucinogens 
 inhalants 
 nicotine 
 opiods 
 PCP 
 sedatives/hypnotics/anxiolytics
Prevalence (lifetime, DSM-IV) 
17.8% alcohol abuse and a 
12.5% alcohol dependence 
12-1.4% drug abuse 
.6% drug dependence
Other rates 
 Alcohol highest for American Indians, then bi-racial 
persons 
 Lowest for Asian (enzyme breaks down alcohol) 
 Males to females 5:1 for alcohol 
 Men higher than women except for prescription drug 
abuse of sedatives, hypnotics, or anti-anxiety drugs.
Co-morbidity 
 Adolescents – 60% 
 Most commonly disruptive disorder, then depression 
 Adults -lifetime prevalence of 70% for at least 1 
mental/emotional disorder 
 Mood disorder 
 anxiety 
 personality disorders 
 Implication – when being seen for other disorders, inquire 
about substance use patterns
Assessment 
Onset, progression, patterns, context, and frequency of use of all 
substances 
Tolerance or withdrawal symptoms 
Major life events 
Other disorders, including the relationship between the onset and 
progression of the symptoms and substance use 
“Triggers” and context of use 
Perceived advantages and disadvantages of use 
Motivations and goals for treatment 
Number of times the individual has quit and the strategies that were used 
Impact of use disorders: 
Financial and legal status 
Education and employment status 
Condition of health (a physical examination may be warranted)
Biological 
 genetic predisposition for alcohol problems 
 neurochemical irregularities implicated with substance 
problems also same with mood, anxiety, impulsive, 
compulsive, personality disorders 
 dopamine - activiating pleasure centers of limbic 
portion of brain (alcohol, cocaine, hallucinogens) 
 norephinephrine-panic response(increased heart rate, 
respiration, and sweating) produced by cocaine and 
amphetamines 
 low levels of serontonin (satisfaction, contentment and 
well-being)
Psychological 
 self-medication 
 cognitive distortions around substance-taking and 
rationalization
Social 
 low socioeconomic status 
 but substance use also has consequences on 
economics 
 peer involvement 
 Women 
 Gay and lesbian
Possible Goals 
reducing or eliminating the substance use 
Controlled drinking controversial 
reducing the physical harm associated with such use 
harm reduction - working with clients to reduce the harmful consequences 
of the behavior, such as reducing the use of substances and encouraging 
the use of condoms and clean needles 
improving psychological and social functioning (mending 
disrupted relationships, reducing impulsivity, building social 
and vocational skills, and maintaining employment) 
relapse prevention 
For adolescents, family focus
Alcoholics Anonymous 
Advantages 
Most common treatment approach 
Little research on AA self-help groups
CBT 
Triggers and avoiding or coping with 
Cognitive distortions around justifying use 
Alternate reinforcers
Motivational Interviewing 
“a client-centered, directive method for enhancing intrinsic 
motivation to change by exploring and resolving 
ambivalence” 
Guiding principles: 
 Listening and expressing empathy 
 Developing discrepancies between problem behavior and 
the client’s goals and values 
 “Rolling” with resistance, which means avoiding power 
struggles and instead making statements that help 
clients argue for change 
 Supporting self-efficacy, or the client’s sense of 
confidence that he or she can change 
 Developing a change plan
Family Involvement 
burden is imposed on families 
when a member has a substance 
use disorder. 
Families can affect the abuser’s 
motivation and ability to comply 
with intervention
Types of family intervention 
 Al-Anon 
 Johnson Institute 
 30% go through with it 
 CRAFT (community reinforcement as a family training 
approach ) 
 Behavioral in nature: family member removes 
drinking conditions, reinforces appropriate behavior, 
gives feedback of inappropriate behavior, and 
provides consequences if behavior exceeds agreed-upon 
limits
Family Intervention, cont. 
 Behavioral couples therapy 
 main objective - to alter interactional patterns maintaining 
chemical abuse and to build a relationship that more effectively 
supports sobriety 
 communication skill-building, planning family activities, 
initiating caring behaviors, and expressing feelings
Family Intervention Adolescents 
 brief strategic family therapy 
Functional family therapy 
multidimensional family therapy 
multisystemic therapy
Pharmacological 
Interventions 
 aversive medications, designed to deter client 
drinking 
 anticraving medications, which purport to reduce 
one’s desire to use substances
Aversive 
 disulfiram (Antabuse) 
 Physicians reluctant to prescribe
Anticraving 
 Naltrexone 
 an opioid receptor antagonist, a substance that blocks opioid receptors in 
the brain, so that the individual fails to experience positive effects from 
opiate (and alcohol use) 
 Acamprosate 
 has been more recently approved by the FDA 
 stabilize a chemical balance in the brain that is otherwise disrupted by 
alcohol abuse, possibly by blocking glutamine receptors while activating 
gamma-aminobutyric acid. 
 for alcohol dependence, acamprosate was better at preventing a relapse, 
and naltrexone was better at preventing a “lapse” from becoming a 
relapse (that is, it prevented heavy drinking)
For heroin, substitution 
therapy 
 methadone and buprenorphine (the latter can be 
prescribed on an outpatient basis) 
 goals being the prevention of withdrawal, the 
elimination of cravings, and the blockage of euphoric 
effects obtained by illegal opiate use
Critique 
 Applicability of criteria for adolescents and elders 
 Part of conduct disorder for adolescents

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Sud 2014

  • 1. SUBSTANCE USE DISORDERS Jacqueline Corcoran, Ph.D. Virginia Commonwealth University School of Social Work
  • 2. DSM 5 change Abuse and dependence subsumed into use disorder Severity: mild, medium, and severe
  • 3. 10 classes  alcohol  Amphetamines  cannabis  cocaine  hallucinogens  inhalants  nicotine  opiods  PCP  sedatives/hypnotics/anxiolytics
  • 4. Prevalence (lifetime, DSM-IV) 17.8% alcohol abuse and a 12.5% alcohol dependence 12-1.4% drug abuse .6% drug dependence
  • 5. Other rates  Alcohol highest for American Indians, then bi-racial persons  Lowest for Asian (enzyme breaks down alcohol)  Males to females 5:1 for alcohol  Men higher than women except for prescription drug abuse of sedatives, hypnotics, or anti-anxiety drugs.
  • 6. Co-morbidity  Adolescents – 60%  Most commonly disruptive disorder, then depression  Adults -lifetime prevalence of 70% for at least 1 mental/emotional disorder  Mood disorder  anxiety  personality disorders  Implication – when being seen for other disorders, inquire about substance use patterns
  • 7. Assessment Onset, progression, patterns, context, and frequency of use of all substances Tolerance or withdrawal symptoms Major life events Other disorders, including the relationship between the onset and progression of the symptoms and substance use “Triggers” and context of use Perceived advantages and disadvantages of use Motivations and goals for treatment Number of times the individual has quit and the strategies that were used Impact of use disorders: Financial and legal status Education and employment status Condition of health (a physical examination may be warranted)
  • 8. Biological  genetic predisposition for alcohol problems  neurochemical irregularities implicated with substance problems also same with mood, anxiety, impulsive, compulsive, personality disorders  dopamine - activiating pleasure centers of limbic portion of brain (alcohol, cocaine, hallucinogens)  norephinephrine-panic response(increased heart rate, respiration, and sweating) produced by cocaine and amphetamines  low levels of serontonin (satisfaction, contentment and well-being)
  • 9. Psychological  self-medication  cognitive distortions around substance-taking and rationalization
  • 10. Social  low socioeconomic status  but substance use also has consequences on economics  peer involvement  Women  Gay and lesbian
  • 11. Possible Goals reducing or eliminating the substance use Controlled drinking controversial reducing the physical harm associated with such use harm reduction - working with clients to reduce the harmful consequences of the behavior, such as reducing the use of substances and encouraging the use of condoms and clean needles improving psychological and social functioning (mending disrupted relationships, reducing impulsivity, building social and vocational skills, and maintaining employment) relapse prevention For adolescents, family focus
  • 12. Alcoholics Anonymous Advantages Most common treatment approach Little research on AA self-help groups
  • 13. CBT Triggers and avoiding or coping with Cognitive distortions around justifying use Alternate reinforcers
  • 14. Motivational Interviewing “a client-centered, directive method for enhancing intrinsic motivation to change by exploring and resolving ambivalence” Guiding principles:  Listening and expressing empathy  Developing discrepancies between problem behavior and the client’s goals and values  “Rolling” with resistance, which means avoiding power struggles and instead making statements that help clients argue for change  Supporting self-efficacy, or the client’s sense of confidence that he or she can change  Developing a change plan
  • 15. Family Involvement burden is imposed on families when a member has a substance use disorder. Families can affect the abuser’s motivation and ability to comply with intervention
  • 16. Types of family intervention  Al-Anon  Johnson Institute  30% go through with it  CRAFT (community reinforcement as a family training approach )  Behavioral in nature: family member removes drinking conditions, reinforces appropriate behavior, gives feedback of inappropriate behavior, and provides consequences if behavior exceeds agreed-upon limits
  • 17. Family Intervention, cont.  Behavioral couples therapy  main objective - to alter interactional patterns maintaining chemical abuse and to build a relationship that more effectively supports sobriety  communication skill-building, planning family activities, initiating caring behaviors, and expressing feelings
  • 18. Family Intervention Adolescents  brief strategic family therapy Functional family therapy multidimensional family therapy multisystemic therapy
  • 19. Pharmacological Interventions  aversive medications, designed to deter client drinking  anticraving medications, which purport to reduce one’s desire to use substances
  • 20. Aversive  disulfiram (Antabuse)  Physicians reluctant to prescribe
  • 21. Anticraving  Naltrexone  an opioid receptor antagonist, a substance that blocks opioid receptors in the brain, so that the individual fails to experience positive effects from opiate (and alcohol use)  Acamprosate  has been more recently approved by the FDA  stabilize a chemical balance in the brain that is otherwise disrupted by alcohol abuse, possibly by blocking glutamine receptors while activating gamma-aminobutyric acid.  for alcohol dependence, acamprosate was better at preventing a relapse, and naltrexone was better at preventing a “lapse” from becoming a relapse (that is, it prevented heavy drinking)
  • 22. For heroin, substitution therapy  methadone and buprenorphine (the latter can be prescribed on an outpatient basis)  goals being the prevention of withdrawal, the elimination of cravings, and the blockage of euphoric effects obtained by illegal opiate use
  • 23. Critique  Applicability of criteria for adolescents and elders  Part of conduct disorder for adolescents