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Virta is the first treatment proven to
reverse type 2 diabetes without
surgery
60% of patients enrolled at one year
achieve normal HbA1c while
eliminating all diabetes-specific
medications
100% of our fees are at risk
$404B
Total Economic Cost
of T2D in US
30M
Number of people
with T2D in US
Source: http://care.diabetesjournals.org/content/early/2019/04/01/dc18-1226
3
1 Hallberg SJ et al. Diabetes Therapy. 2018;9(2):583-612. For patients completing 1 year of treatment.
Virta has delivered
diabetes reversal at scale
$4,800
Total annual estimated cost
savings, per patient per year
Medical Spend
94%
Patients eliminating/
reducing insulin
Insulin Reduction1
60%
Patients that achieve sub-diabetic A1c
without diabetes-specific medications
Diabetes Reversal1
Diabetes Reversal: Achieving blood sugar control while reducing medications
Hallberg SJ et al. Diabetes Therapy. 2018;9(2):583-612.
Blood Sugar Changes Over Time
Average HbA1C for patients enrolled one year
60%
Reversal
At 12 months into
Virta treatment
Additional Health Improvements: Significant weight loss
Weight Loss Over Time
Average weight change as a percentage of starting weight
86%
of patients lost > 5%
61%
of patients lost > 10%
At 12 months into
Virta treatment
Hallberg SJ et al. Subanalysis of one year completers. Diabetes Therapy. 2018;9(2):583-612.
Threshold for clinical significance
The need for diabetes-specific medications continues to
drop, even at 2 years
The largest and longest clinical trial ever published on diabetes reversal
“Low carbohydrate eating plans may
result in improved glycemia... and the
potential to reduce antihyperglycemic
medications.”
Major Publications Citations in ADA Evidence-Based
Standards of Care
“Carbohydrate-restricted
eating pattern...does not appear to
increase overall cardiovascular risk.”
Sustainability of
Improved
Health Outcomes
(T2D Reversal)
1 year outcomes
Rapid Impact on
Type 2 Diabetes
10 week outcomes
Significant Improvement
on Cardiovascular Risk
Factors
1 year outcomes
NAFLD
Improvement / Reversal
1 year outcomes
Sleep Quality
1 year outcomes
Dr. Amy McKenzie (PhD, Virta): National Lipid Association Young Investigator of the year award (2018)
Dr. Amy McKenzie (PhD, Virta): American Diabetes Association Young investigator of the year award (2018)
Long term Effects
(T2D Reversal)
2 year outcomes
Licensed Virta physicians and health
coaches providing real-time,
individualized care at scale
Virta Continuous
Remote Care™
Clinically-proven medical
nutrition therapy based
on years of research
Virta
Reverse™
Virta has created a new diabetes care category...
Prevention via Weight Loss Management Using Drugs Diabetes Reversal
“Two years ago my A1C was
10.2 and my doctor told me
I had a 40% chance of having
a stroke or heart attack—
I was only 40 years old.
Virta literally saved my life!"
...and is a different kind
of health care company
The partnership with Virta would add to the
current type 2 diabetes care offered by VA.
Veterans would receive continuous telehealth
support from Virta’s care team, comprised of
medical providers and health coaches, and
close guidance in following an individualized
nutrition plan based on carbohydrate
restriction.”
US Department of Veterans
Affairs is taking notice
“
I didn’t know my
diabetes could be
reversed…
I thought it was
a life sentence.”
Lori R.
Virta Patient
“
Robert E. Ratner, MD
Former Chief Scientific & Medical Officer,
American Diabetes Association
“If we can get this treatment to more and more
Americans, we can have a huge impact on their
lives and reduce one of the most significant
drivers of healthcare cost growth.”
Evidence for a new category of diabetes care reversal

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Evidence for a new category of diabetes care reversal

  • 1. Virta is the first treatment proven to reverse type 2 diabetes without surgery 60% of patients enrolled at one year achieve normal HbA1c while eliminating all diabetes-specific medications 100% of our fees are at risk
  • 2. $404B Total Economic Cost of T2D in US 30M Number of people with T2D in US Source: http://care.diabetesjournals.org/content/early/2019/04/01/dc18-1226
  • 3. 3
  • 4. 1 Hallberg SJ et al. Diabetes Therapy. 2018;9(2):583-612. For patients completing 1 year of treatment. Virta has delivered diabetes reversal at scale $4,800 Total annual estimated cost savings, per patient per year Medical Spend 94% Patients eliminating/ reducing insulin Insulin Reduction1 60% Patients that achieve sub-diabetic A1c without diabetes-specific medications Diabetes Reversal1
  • 5. Diabetes Reversal: Achieving blood sugar control while reducing medications Hallberg SJ et al. Diabetes Therapy. 2018;9(2):583-612. Blood Sugar Changes Over Time Average HbA1C for patients enrolled one year 60% Reversal At 12 months into Virta treatment
  • 6. Additional Health Improvements: Significant weight loss Weight Loss Over Time Average weight change as a percentage of starting weight 86% of patients lost > 5% 61% of patients lost > 10% At 12 months into Virta treatment Hallberg SJ et al. Subanalysis of one year completers. Diabetes Therapy. 2018;9(2):583-612. Threshold for clinical significance
  • 7. The need for diabetes-specific medications continues to drop, even at 2 years
  • 8. The largest and longest clinical trial ever published on diabetes reversal “Low carbohydrate eating plans may result in improved glycemia... and the potential to reduce antihyperglycemic medications.” Major Publications Citations in ADA Evidence-Based Standards of Care “Carbohydrate-restricted eating pattern...does not appear to increase overall cardiovascular risk.” Sustainability of Improved Health Outcomes (T2D Reversal) 1 year outcomes Rapid Impact on Type 2 Diabetes 10 week outcomes Significant Improvement on Cardiovascular Risk Factors 1 year outcomes NAFLD Improvement / Reversal 1 year outcomes Sleep Quality 1 year outcomes Dr. Amy McKenzie (PhD, Virta): National Lipid Association Young Investigator of the year award (2018) Dr. Amy McKenzie (PhD, Virta): American Diabetes Association Young investigator of the year award (2018) Long term Effects (T2D Reversal) 2 year outcomes
  • 9. Licensed Virta physicians and health coaches providing real-time, individualized care at scale Virta Continuous Remote Care™ Clinically-proven medical nutrition therapy based on years of research Virta Reverse™
  • 10.
  • 11. Virta has created a new diabetes care category... Prevention via Weight Loss Management Using Drugs Diabetes Reversal
  • 12. “Two years ago my A1C was 10.2 and my doctor told me I had a 40% chance of having a stroke or heart attack— I was only 40 years old. Virta literally saved my life!" ...and is a different kind of health care company
  • 13. The partnership with Virta would add to the current type 2 diabetes care offered by VA. Veterans would receive continuous telehealth support from Virta’s care team, comprised of medical providers and health coaches, and close guidance in following an individualized nutrition plan based on carbohydrate restriction.” US Department of Veterans Affairs is taking notice “
  • 14. I didn’t know my diabetes could be reversed… I thought it was a life sentence.” Lori R. Virta Patient “
  • 15. Robert E. Ratner, MD Former Chief Scientific & Medical Officer, American Diabetes Association “If we can get this treatment to more and more Americans, we can have a huge impact on their lives and reduce one of the most significant drivers of healthcare cost growth.”