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The Innovative Medicines Initiative:
  Promoting patient involvement
      in drug development

            Michel Goldman, MD, PhD
               Executive Director



       EUPATI Launch, Copenhagen, 27 March 2012
Innovative Medicines Initiative:
Joining public and private forces




                    2 Billion Euro
                   1 Billion €    1 Billion €



                  Public                 Private
                           Partnership
Core objectives

 • To overcome research bottlenecks in drug
   development through collaborative approaches

 • To increase investments in the biopharmaceutical
   sector and provide socio-economic benefits across
   Europe

 • To contribute to the health of European citizens
Key concepts


• Non-competitive research for EFPIA companies



• Competitive calls for IMI beneficiaries


• Open collaboration in public-private consortia
Major project deliverables


   • Patient-reported outcomes

   • Predicting biomarkers

   • Novel approaches to drug safety

   • Innovative tools for translational research
PRO-ACTIVE
Patient reported outcomes in chronic
obstructive pulmonary disease

              Activity Monitoring

              PDA for PROs

                                    Physical activity




                                    Symptoms reported


                      Time (days)
U-BIOPRED
 Towards a new taxonomy of asthma
Paves the way towards tailored treatments for
asthmatic patients

38 Partners
     - 9 EFPIA companies
     - 23 Academic institutions
     - 3 Patients’ organizations
     - 3 SMEs


First achievements
    A new stepwise algorithm for the stratification
     of patients with severe asthma



                                                       Thorax, 66: 910-7 (2011)
Clinical Pharmacology & Therapeutics March 2012,
http://www.nature.com/doifinder/10.1038/clpt.2011.321
Nature Medicine 18:341,
2012
www.imi.europa.eu

   THANK YOU !

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EUPATI launch meeting - Michel Goldman IMI

  • 1. The Innovative Medicines Initiative: Promoting patient involvement in drug development Michel Goldman, MD, PhD Executive Director EUPATI Launch, Copenhagen, 27 March 2012
  • 2. Innovative Medicines Initiative: Joining public and private forces 2 Billion Euro 1 Billion € 1 Billion € Public Private Partnership
  • 3. Core objectives • To overcome research bottlenecks in drug development through collaborative approaches • To increase investments in the biopharmaceutical sector and provide socio-economic benefits across Europe • To contribute to the health of European citizens
  • 4. Key concepts • Non-competitive research for EFPIA companies • Competitive calls for IMI beneficiaries • Open collaboration in public-private consortia
  • 5. Major project deliverables • Patient-reported outcomes • Predicting biomarkers • Novel approaches to drug safety • Innovative tools for translational research
  • 6. PRO-ACTIVE Patient reported outcomes in chronic obstructive pulmonary disease Activity Monitoring PDA for PROs Physical activity Symptoms reported Time (days)
  • 7. U-BIOPRED Towards a new taxonomy of asthma Paves the way towards tailored treatments for asthmatic patients 38 Partners - 9 EFPIA companies - 23 Academic institutions - 3 Patients’ organizations - 3 SMEs First achievements  A new stepwise algorithm for the stratification of patients with severe asthma Thorax, 66: 910-7 (2011)
  • 8. Clinical Pharmacology & Therapeutics March 2012, http://www.nature.com/doifinder/10.1038/clpt.2011.321
  • 10. www.imi.europa.eu THANK YOU !