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A Biomedical Big Data Analytics Leader
®
© 2016 Quertle, LLC
Quertle is driving the transformation from
ordinary search discovery and analytics
© 2016 Quertle, LLC
Current approaches are broken: Too much data, too much noise,
and getting worse with >2M new documents each year.
We have the solution.
The Problem: Biomedical Literature Tsunami
> 20 million
professionals
> 200,000
searches this minute
95%
miss critical information
$80B
wasted every year
Untold
lives lost
Impact
Sources: WHO, Bureau of Labor Statistics, National Library of Medicine, European Patent Office, & more
© 2016 Quertle, LLC
Quertle Biomedical Big Data Platform
• More comprehensive,
more precise results
• Automatic concept discovery
provides intuitive exploration
• Relationship discovery
CONCEPT-ORIENTED DATABASE
40M documents
>10M full-text
MULTI-COMPONENT ENGINE
Artificial Intelligence
Advanced Linguistics
Computational Statistics
Pattern Matching
Quantum Logic
PREDICTIVE VISUAL ANALYTICS
Concept Interactions
Concept Strength
Trends
• Critical content
– Journal articles, Patents, NIH
Grants, Protocols, etc.
– Client’s in-house content
• High-performance searching
in <0.3 sec
• Connections that cannot be
discovered anywhere else
• Actionable knowledge
• Highly relevant results, essential
for valid analytics
© 2016 Quertle, LLC
• TP53 is a medically important gene involved in >50% of cancers
• Searching for any of its names should find ALL of the relevant documents
The typical searcher does not even realize what they are missing with other “solutions”!!
Case Study: Quertle Outperforms
Method TP53 p53 TRP53 BCC7
AI + more >99% >99% >99% >99%
Keyword 9% 60% 23% 0%
Semantics 9% 60% 23% 0%
Semantics 54% 71% 54% 0%
All searches done on the same content on 20 June 2016. Logos and names are trademarks of their respective owners.
© 2016 Quertle, LLC
Query: NO $Diseases
Key Points:
• Quertle “knows” that NO means “nitric oxide”
– Searching for “nitric oxide” on PubMed misses the 20% of the literature that ONLY uses “NO”
• The Power Term™ $Diseases means search for all diseases (e.g., diabetes, hypertension) and do not clutter the
results with hits that only have generic terms such as “disease” or “malady”)
– The Power Term in this query answers the question “What diseases are associated with NO?”
• Automatic discovery of Key Concepts (related to your query) provides a global view of the content and an
intuitive means for exploration
Live Demonstration
© 2016 Quertle, LLC
Case Study
Question: What genes might work together to contribute to
melanoma?
Query: $Genes melanoma
Predictive Visual Analysis: Adjacent genes with similar
colors in the matrix may contribute to melanoma in
concert
Example Conclusion: The interaction of SOX9 and
CEACAM1 in melanoma warrants further research
Quertle Big Data Platform: Visual Analytics
Quertle discovers connections that cannot be found
with any competing tool
© 2016 Quertle, LLC
Quertle Big Data Platform: Visual Analytics
Case Study
Question: What cardiovascular diseases will have the
greatest economic impact?
Query: cardiovascular disease $Cost
Predictive Visual Analysis: The size of the blue (disease)
bubbles is impact of that disease to the economy. Blue
border indicates decreasing trend, red increasing.
Example Conclusion: The cost of stroke and hypertension
are of great concern now, but hypertension maybe less
impactful in time.
Hypertension Stroke
Quertle uncovers trends that are not discernable
with any competing tool
© 2016 Quertle, LLC
Testimonials
Quertle’s discovery system is ahead of its time. Join the evolution! - Oliver Renn, Head of the Chemistry & Biology Information Center, ETH Zürich
Quetzal is a very unique literature study tool, and it is truly peerless in the field. - Yibu Chen, Bioinformaticist, USC
Quertle is not your average search engine; it is a powerhouse. – Antonio DeRosa, Memorial Sloan Kettering Cancer Center
[The] preferred way of searching. - Bonnie Swogger, Science and Technology Librarian, SUNY Geneseo
Students love Quertle’s search engine and, when surveyed, highly preferred it to PubMed. - Robin Cresiski, Provost, Nevada State College
Quertle offers a uniquely effective way to execute a combined search of the biomedical literature - Texas Medical Center Library
Quertle gives you exactly what you are asking for. - Ansuman Chattopadhyay and Carrie Iwema, University of Pittsburgh
QUERTLE是第三代语义元搜索引擎 - Gongqing Xia and Lei Runling, Xi'an Jiaotong University
Nobody else organizes, searches, and analyzes biomedical scholarly
information the way Quertle does!
© 2016 Quertle, LLC
Our Customers are World-wide
© 2016 Quertle, LLC
Awards, Press, and Accolades
The US National Library of Medicine, the world’s
largest biomedical library and center for information
advancement, honored Quertle for its innovation in
searching and investigating the biomedical literature.
© 2016 Quertle, LLC
• Quertle has already solved critical issues in AI-based and full-text searching
• Quertle is experienced working with partners to custom-build solutions
• Quertle can provide immediate implementation of the Discovery and Analytics Platform (inc. visualizations)
• Subsequent implementation of a white-labeled version including
– Integration of additional public and/or private content
– Custom-built search and analytic functions
– Tailored ontologies and Power Terms
– Full API for integrating search capabilities
Why Work with Quertle
Quertle can implement solutions today that will take others years
© 2016 Quertle, LLC
Quertle Technologies
Quantum
Logic
Computational
Statistics
Big Data
Computational
Linguistics
Pattern
Matching
Artificial
Intelligence
Biostatistics
Predictive
Analytics
Text Analytics
Information
Visualization
Ontology
Development
Text Mining
© 2016 Quertle, LLC
• IP-based recognition for easy access to your full-text documents
• Automatic alerts
• Full-encryption of communications and all information saved on the server
• Save and annotate specific results
• Private Journal Clubs
• Export results
Other Capabilities
© 2016 Quertle, LLC
Jeffrey Saffer, Ph.D. – President and CEO
Founder of OmniViz (a data visualization and
Head, Molecular Biosciences Department at the
National Laboratory
Ph.D. from Yale University (Molecular Biophysics
 Strong executive management skills
10 patents granted, 1 application pending, 50
chapters
R&D 100, NLM Innovation Challenge winner,
The Experienced Leadership
Vicki Burnett, Ph.D. – Executive VP & COO
Executive VP, OmniViz, Head of Health
Intelligence; major contributor to successful exit
Associate Professor at University of Arizona
Health Sciences Center
Ph.D. from University of North Carolina, Duke,
North Carolina State Integrated Toxicology
Program (Molecular Toxicology)
 Strong operations management skills
1 patent application pending, 24 journal
articles/book chapters
NLM Innovation Challenge winner
© 2016 Quertle, LLC
• James Canton, Institute for Global Futures – World-renowned
global futurist, visionary business advisor
• Peter van der Spek, Ph.D., Erasmus Medical Center – One of the
world’s leading bioinformaticists
• Tamjidul Hoque, University of New Orleans – AI and machine
learning expert
• Tony Trippe, PatInformatics LLC – One of the top 300 IP
Strategists in the world
• Julie Glanville, York Health Economics Consortium – Leading
medical literature search and analysis expert
Advisory Board
© 2016 Quertle, LLC
For more detailed information about Quertle, contact:
Janet Delicata
(586) 649-3800
delicata@Quertle.com
#JanetatQuertle
www.Quertle.com
www.Quetzal-Search.info
Path Forward
Let us become part of your team!

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Working with Quertle

  • 1. A Biomedical Big Data Analytics Leader ® © 2016 Quertle, LLC
  • 2. Quertle is driving the transformation from ordinary search discovery and analytics
  • 3. © 2016 Quertle, LLC Current approaches are broken: Too much data, too much noise, and getting worse with >2M new documents each year. We have the solution. The Problem: Biomedical Literature Tsunami > 20 million professionals > 200,000 searches this minute 95% miss critical information $80B wasted every year Untold lives lost Impact Sources: WHO, Bureau of Labor Statistics, National Library of Medicine, European Patent Office, & more
  • 4. © 2016 Quertle, LLC Quertle Biomedical Big Data Platform • More comprehensive, more precise results • Automatic concept discovery provides intuitive exploration • Relationship discovery CONCEPT-ORIENTED DATABASE 40M documents >10M full-text MULTI-COMPONENT ENGINE Artificial Intelligence Advanced Linguistics Computational Statistics Pattern Matching Quantum Logic PREDICTIVE VISUAL ANALYTICS Concept Interactions Concept Strength Trends • Critical content – Journal articles, Patents, NIH Grants, Protocols, etc. – Client’s in-house content • High-performance searching in <0.3 sec • Connections that cannot be discovered anywhere else • Actionable knowledge • Highly relevant results, essential for valid analytics
  • 5. © 2016 Quertle, LLC • TP53 is a medically important gene involved in >50% of cancers • Searching for any of its names should find ALL of the relevant documents The typical searcher does not even realize what they are missing with other “solutions”!! Case Study: Quertle Outperforms Method TP53 p53 TRP53 BCC7 AI + more >99% >99% >99% >99% Keyword 9% 60% 23% 0% Semantics 9% 60% 23% 0% Semantics 54% 71% 54% 0% All searches done on the same content on 20 June 2016. Logos and names are trademarks of their respective owners.
  • 6. © 2016 Quertle, LLC Query: NO $Diseases Key Points: • Quertle “knows” that NO means “nitric oxide” – Searching for “nitric oxide” on PubMed misses the 20% of the literature that ONLY uses “NO” • The Power Term™ $Diseases means search for all diseases (e.g., diabetes, hypertension) and do not clutter the results with hits that only have generic terms such as “disease” or “malady”) – The Power Term in this query answers the question “What diseases are associated with NO?” • Automatic discovery of Key Concepts (related to your query) provides a global view of the content and an intuitive means for exploration Live Demonstration
  • 7. © 2016 Quertle, LLC Case Study Question: What genes might work together to contribute to melanoma? Query: $Genes melanoma Predictive Visual Analysis: Adjacent genes with similar colors in the matrix may contribute to melanoma in concert Example Conclusion: The interaction of SOX9 and CEACAM1 in melanoma warrants further research Quertle Big Data Platform: Visual Analytics Quertle discovers connections that cannot be found with any competing tool
  • 8. © 2016 Quertle, LLC Quertle Big Data Platform: Visual Analytics Case Study Question: What cardiovascular diseases will have the greatest economic impact? Query: cardiovascular disease $Cost Predictive Visual Analysis: The size of the blue (disease) bubbles is impact of that disease to the economy. Blue border indicates decreasing trend, red increasing. Example Conclusion: The cost of stroke and hypertension are of great concern now, but hypertension maybe less impactful in time. Hypertension Stroke Quertle uncovers trends that are not discernable with any competing tool
  • 9. © 2016 Quertle, LLC Testimonials Quertle’s discovery system is ahead of its time. Join the evolution! - Oliver Renn, Head of the Chemistry & Biology Information Center, ETH Zürich Quetzal is a very unique literature study tool, and it is truly peerless in the field. - Yibu Chen, Bioinformaticist, USC Quertle is not your average search engine; it is a powerhouse. – Antonio DeRosa, Memorial Sloan Kettering Cancer Center [The] preferred way of searching. - Bonnie Swogger, Science and Technology Librarian, SUNY Geneseo Students love Quertle’s search engine and, when surveyed, highly preferred it to PubMed. - Robin Cresiski, Provost, Nevada State College Quertle offers a uniquely effective way to execute a combined search of the biomedical literature - Texas Medical Center Library Quertle gives you exactly what you are asking for. - Ansuman Chattopadhyay and Carrie Iwema, University of Pittsburgh QUERTLE是第三代语义元搜索引擎 - Gongqing Xia and Lei Runling, Xi'an Jiaotong University Nobody else organizes, searches, and analyzes biomedical scholarly information the way Quertle does!
  • 10. © 2016 Quertle, LLC Our Customers are World-wide
  • 11. © 2016 Quertle, LLC Awards, Press, and Accolades The US National Library of Medicine, the world’s largest biomedical library and center for information advancement, honored Quertle for its innovation in searching and investigating the biomedical literature.
  • 12. © 2016 Quertle, LLC • Quertle has already solved critical issues in AI-based and full-text searching • Quertle is experienced working with partners to custom-build solutions • Quertle can provide immediate implementation of the Discovery and Analytics Platform (inc. visualizations) • Subsequent implementation of a white-labeled version including – Integration of additional public and/or private content – Custom-built search and analytic functions – Tailored ontologies and Power Terms – Full API for integrating search capabilities Why Work with Quertle Quertle can implement solutions today that will take others years
  • 13. © 2016 Quertle, LLC Quertle Technologies Quantum Logic Computational Statistics Big Data Computational Linguistics Pattern Matching Artificial Intelligence Biostatistics Predictive Analytics Text Analytics Information Visualization Ontology Development Text Mining
  • 14. © 2016 Quertle, LLC • IP-based recognition for easy access to your full-text documents • Automatic alerts • Full-encryption of communications and all information saved on the server • Save and annotate specific results • Private Journal Clubs • Export results Other Capabilities
  • 15. © 2016 Quertle, LLC Jeffrey Saffer, Ph.D. – President and CEO Founder of OmniViz (a data visualization and Head, Molecular Biosciences Department at the National Laboratory Ph.D. from Yale University (Molecular Biophysics  Strong executive management skills 10 patents granted, 1 application pending, 50 chapters R&D 100, NLM Innovation Challenge winner, The Experienced Leadership Vicki Burnett, Ph.D. – Executive VP & COO Executive VP, OmniViz, Head of Health Intelligence; major contributor to successful exit Associate Professor at University of Arizona Health Sciences Center Ph.D. from University of North Carolina, Duke, North Carolina State Integrated Toxicology Program (Molecular Toxicology)  Strong operations management skills 1 patent application pending, 24 journal articles/book chapters NLM Innovation Challenge winner
  • 16. © 2016 Quertle, LLC • James Canton, Institute for Global Futures – World-renowned global futurist, visionary business advisor • Peter van der Spek, Ph.D., Erasmus Medical Center – One of the world’s leading bioinformaticists • Tamjidul Hoque, University of New Orleans – AI and machine learning expert • Tony Trippe, PatInformatics LLC – One of the top 300 IP Strategists in the world • Julie Glanville, York Health Economics Consortium – Leading medical literature search and analysis expert Advisory Board
  • 17. © 2016 Quertle, LLC For more detailed information about Quertle, contact: Janet Delicata (586) 649-3800 delicata@Quertle.com #JanetatQuertle www.Quertle.com www.Quetzal-Search.info Path Forward Let us become part of your team!

Notes de l'éditeur

  1. Semantics and NLP have not lived up to expectations
  2. Most a trade secret One patent pending
  3. [QUERTLE semantic metadata is the third generation of search engines]