SlideShare une entreprise Scribd logo
1  sur  28
Optomechanical measurement and FE modeling
of tympanic membrane mechanics
Jef Aernouts
Laboratory of Biomedical Physics (BIMEF)
University of Antwerp

Presentation at Philips Group Innovation
October 5, 2012
Optomechanical measurement and FE modeling
of tympanic membrane mechanics




                                             1
The human ear




       tympanic
       membrane



                  2
Function of the ear

Convert sound (20-20000 Hz) > nerve activity in our brain




             What is role middle ear?
                                                            3
Why study TM mechanics?

• Middle ear finite element modeling

                                                   tympanic membrane!




          normal
(Aerts J, Aernouts J. 2012)                            reconstructed
                                diseased               (Kelly et al., 2003)
                              (Gan et al., 2009)
                                                                              4
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  5
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  6
Human tympanic membrane

- Base diameter: 9 mm
- Apex height: 1.7 mm




                            7
Needle indentation

• Approach
  - Apply indentations
  - Measure forces




                         (1) TM, (2): force transducer,
                         (3): piston, (4): LVDT , (5): signal
                         generator, (6): feedback control unit


                                                                 8
Needle indentation

• Approach
  - Apply indentations
  - Measure forces


• Sample preparation




                                  9
Needle indentation

• Approach
  - Apply indentations
  - Measure forces


• Sample preparation

• Shape measurement




                                  10
Needle indentation
                             In rest
• Approach
  - Apply indentations
  - Measure forces


• Sample preparation

                             Indented
• Shape measurement

• Finite element model



                                        11
Needle indentation

• Approach
  - Apply indentations
  - Measure forces


• Sample preparation

• Shape measurement

• Finite element model
  - Fit experiments



                                  12
13
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  14
TM vibrations

• Sample




                           15
TM vibrations

• Sample

• Stroboscopic holography
  - Sounds: 0.5 kHz –
    19 kHz, 80-120 dB
  - Full-field displacement




                                 16
Holography

• Principle




                           CCD




                             17
Holography

• Principle

• Stroboscopic holography




                             18
probe microphone



                  speaker

                                     holography setup




sample




         camera
FE model

• Geometry (from micro-CT)
• Boundary conditions & Loadings




                     sound wave
                                   20
TM full-field displacement


- Measured with stroboscopic holography:




                                           21
TM full-field displacement


- Measured with stroboscopic holography:
- Finite element outcome




                                           22
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  23
Middle ear FE model results




1000 Hz     7000 Hz      16000 Hz
 (x8e3)      (x3e4)       (x2e5)



                                    24
Thanks for your attention!

• Questions? I’m all ears…




                                   25
TM curvature

• Cochlear load at umbo (tip malleus)
• Natural curved versus artificially flat




                                            26
TM curvature
                           800 Hz – 4 kHz:
• Umbo velocity response   17.5 dB difference




                                                27

Contenu connexe

Tendances

Image quality, digital technology and radiation protection
Image quality, digital technology and radiation protectionImage quality, digital technology and radiation protection
Image quality, digital technology and radiation protection
Rad Tech
 
Guillet mottin 2005 spie_ 5964
Guillet mottin 2005 spie_ 5964Guillet mottin 2005 spie_ 5964
Guillet mottin 2005 spie_ 5964
Stéphane MOTTIN
 
Fluoroscopy systems
Fluoroscopy systemsFluoroscopy systems
Fluoroscopy systems
Rad Tech
 
radiology-image-characteristics
 radiology-image-characteristics radiology-image-characteristics
radiology-image-characteristics
Parth Thakkar
 
ETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdfETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdf
mashiur
 

Tendances (17)

PRINCIPLES OF SHADOW CASTING
PRINCIPLES OF SHADOW CASTINGPRINCIPLES OF SHADOW CASTING
PRINCIPLES OF SHADOW CASTING
 
Study of middle ear mechanics at the Lab of Biomedical Physics: an overview
Study of middle ear mechanics at the Lab of Biomedical Physics: an overviewStudy of middle ear mechanics at the Lab of Biomedical Physics: an overview
Study of middle ear mechanics at the Lab of Biomedical Physics: an overview
 
projection geometry
projection geometryprojection geometry
projection geometry
 
Intro to US_Hitachi and Dr Peter
Intro to US_Hitachi and Dr PeterIntro to US_Hitachi and Dr Peter
Intro to US_Hitachi and Dr Peter
 
Image quality, digital technology and radiation protection
Image quality, digital technology and radiation protectionImage quality, digital technology and radiation protection
Image quality, digital technology and radiation protection
 
SPECT
SPECTSPECT
SPECT
 
Radiology in orthodontics dr.kavitha /certified fixed orthodontic courses by ...
Radiology in orthodontics dr.kavitha /certified fixed orthodontic courses by ...Radiology in orthodontics dr.kavitha /certified fixed orthodontic courses by ...
Radiology in orthodontics dr.kavitha /certified fixed orthodontic courses by ...
 
Evaluation of rock properties and rock structures in the μ-range with sub-μ X...
Evaluation of rock properties and rock structures in the μ-range with sub-μ X...Evaluation of rock properties and rock structures in the μ-range with sub-μ X...
Evaluation of rock properties and rock structures in the μ-range with sub-μ X...
 
Ideal radiograph
Ideal radiographIdeal radiograph
Ideal radiograph
 
Fluoroscopy for Residents in Radiology
Fluoroscopy for Residents in RadiologyFluoroscopy for Residents in Radiology
Fluoroscopy for Residents in Radiology
 
Guillet mottin 2005 spie_ 5964
Guillet mottin 2005 spie_ 5964Guillet mottin 2005 spie_ 5964
Guillet mottin 2005 spie_ 5964
 
Viewing and recording the fluoroscopic image
Viewing and recording the fluoroscopic imageViewing and recording the fluoroscopic image
Viewing and recording the fluoroscopic image
 
Diffractive Optics Manufacturing
Diffractive Optics ManufacturingDiffractive Optics Manufacturing
Diffractive Optics Manufacturing
 
Fluoroscopy systems
Fluoroscopy systemsFluoroscopy systems
Fluoroscopy systems
 
radiology-image-characteristics
 radiology-image-characteristics radiology-image-characteristics
radiology-image-characteristics
 
Medical Equipment lec 7 Radiography detectors
Medical Equipment lec 7 Radiography detectorsMedical Equipment lec 7 Radiography detectors
Medical Equipment lec 7 Radiography detectors
 
ETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdfETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdf
 

En vedette (9)

The ear
The earThe ear
The ear
 
Metabolic Disorders
Metabolic DisordersMetabolic Disorders
Metabolic Disorders
 
Presentation1.pptx, ct high resolution anatomy of the petrous bone.
Presentation1.pptx, ct high resolution anatomy of the petrous bone.Presentation1.pptx, ct high resolution anatomy of the petrous bone.
Presentation1.pptx, ct high resolution anatomy of the petrous bone.
 
The ear. auditory pathway and olfactory pathway
The ear. auditory pathway and olfactory pathwayThe ear. auditory pathway and olfactory pathway
The ear. auditory pathway and olfactory pathway
 
Auditory pathways of the brain
Auditory pathways of the brainAuditory pathways of the brain
Auditory pathways of the brain
 
Tympanic membrane perforation
Tympanic membrane perforationTympanic membrane perforation
Tympanic membrane perforation
 
Anatomy of ear
Anatomy of earAnatomy of ear
Anatomy of ear
 
External ear,tympanic membrane and auditory tube Dr.N.Mugunthan.M.S.,
External ear,tympanic membrane and auditory tube  Dr.N.Mugunthan.M.S.,External ear,tympanic membrane and auditory tube  Dr.N.Mugunthan.M.S.,
External ear,tympanic membrane and auditory tube Dr.N.Mugunthan.M.S.,
 
Tympanic membrane
Tympanic membraneTympanic membrane
Tympanic membrane
 

Similaire à Optomechanical measurement and FE modeling of tympanic membrane mechanics

ETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdfETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdf
mashiur
 
pachymetry confocal microscopy cornea ophthalmology diagnostics
pachymetry confocal microscopy cornea ophthalmology diagnosticspachymetry confocal microscopy cornea ophthalmology diagnostics
pachymetry confocal microscopy cornea ophthalmology diagnostics
Paavan Kalra
 
iMinds The Conference: Wim van Aarle
iMinds The Conference: Wim van AarleiMinds The Conference: Wim van Aarle
iMinds The Conference: Wim van Aarle
imec
 
ResearchLabPresentation
ResearchLabPresentationResearchLabPresentation
ResearchLabPresentation
Brianna Weibye
 
Monte Carlo comparison study of the radiation absorption of scintillators for...
Monte Carlo comparison study of the radiation absorption of scintillators for...Monte Carlo comparison study of the radiation absorption of scintillators for...
Monte Carlo comparison study of the radiation absorption of scintillators for...
Anax Fotopoulos
 
DNA translocation through a nanopore
DNA translocation through a nanoporeDNA translocation through a nanopore
DNA translocation through a nanopore
kunyan
 

Similaire à Optomechanical measurement and FE modeling of tympanic membrane mechanics (20)

UCSF Hyperpolarized MR #4: Acquisition and RF Coils (2019)
UCSF Hyperpolarized MR #4: Acquisition and RF Coils (2019)UCSF Hyperpolarized MR #4: Acquisition and RF Coils (2019)
UCSF Hyperpolarized MR #4: Acquisition and RF Coils (2019)
 
ETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdfETE444-lec2-atomic_scale_characterization_techniques.pdf
ETE444-lec2-atomic_scale_characterization_techniques.pdf
 
pachymetry confocal microscopy cornea ophthalmology diagnostics
pachymetry confocal microscopy cornea ophthalmology diagnosticspachymetry confocal microscopy cornea ophthalmology diagnostics
pachymetry confocal microscopy cornea ophthalmology diagnostics
 
Microscopy
MicroscopyMicroscopy
Microscopy
 
iMinds The Conference: Wim van Aarle
iMinds The Conference: Wim van AarleiMinds The Conference: Wim van Aarle
iMinds The Conference: Wim van Aarle
 
Magnetic resonance imaging
Magnetic resonance imagingMagnetic resonance imaging
Magnetic resonance imaging
 
Rotary ii
Rotary iiRotary ii
Rotary ii
 
AFM and STM (Scanning probe microscopy)
AFM and STM (Scanning probe microscopy)AFM and STM (Scanning probe microscopy)
AFM and STM (Scanning probe microscopy)
 
OCT
OCTOCT
OCT
 
Otoacoustic Emissions : A comparison between simulation and lab measures.
Otoacoustic Emissions : A comparison between simulation and lab measures.Otoacoustic Emissions : A comparison between simulation and lab measures.
Otoacoustic Emissions : A comparison between simulation and lab measures.
 
ResearchLabPresentation
ResearchLabPresentationResearchLabPresentation
ResearchLabPresentation
 
fields.ppt
fields.pptfields.ppt
fields.ppt
 
Imaging in orthopaedics
Imaging in orthopaedicsImaging in orthopaedics
Imaging in orthopaedics
 
Microscopic examination using Atomic force microscopy and Confocal scanning ...
Microscopic examination using  Atomic force microscopy and Confocal scanning ...Microscopic examination using  Atomic force microscopy and Confocal scanning ...
Microscopic examination using Atomic force microscopy and Confocal scanning ...
 
Monte Carlo comparison study of the radiation absorption of scintillators for...
Monte Carlo comparison study of the radiation absorption of scintillators for...Monte Carlo comparison study of the radiation absorption of scintillators for...
Monte Carlo comparison study of the radiation absorption of scintillators for...
 
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3TSubmillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
 
Cbct
CbctCbct
Cbct
 
DNA translocation through a nanopore
DNA translocation through a nanoporeDNA translocation through a nanopore
DNA translocation through a nanopore
 
Raman and Coherent anti-Stokes Raman Scattering (CARS) Spectroscopy and Imaging
Raman and Coherent anti-Stokes Raman Scattering (CARS) Spectroscopy and Imaging Raman and Coherent anti-Stokes Raman Scattering (CARS) Spectroscopy and Imaging
Raman and Coherent anti-Stokes Raman Scattering (CARS) Spectroscopy and Imaging
 
Nanonics - Raman MultiProbe
Nanonics - Raman MultiProbeNanonics - Raman MultiProbe
Nanonics - Raman MultiProbe
 

Dernier

Architecting Cloud Native Applications
Architecting Cloud Native ApplicationsArchitecting Cloud Native Applications
Architecting Cloud Native Applications
WSO2
 
Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024
Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024
Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024
Victor Rentea
 
Finding Java's Hidden Performance Traps @ DevoxxUK 2024
Finding Java's Hidden Performance Traps @ DevoxxUK 2024Finding Java's Hidden Performance Traps @ DevoxxUK 2024
Finding Java's Hidden Performance Traps @ DevoxxUK 2024
Victor Rentea
 
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Safe Software
 

Dernier (20)

Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
 
Corporate and higher education May webinar.pptx
Corporate and higher education May webinar.pptxCorporate and higher education May webinar.pptx
Corporate and higher education May webinar.pptx
 
Apidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, Adobe
Apidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, AdobeApidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, Adobe
Apidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, Adobe
 
Introduction to use of FHIR Documents in ABDM
Introduction to use of FHIR Documents in ABDMIntroduction to use of FHIR Documents in ABDM
Introduction to use of FHIR Documents in ABDM
 
Architecting Cloud Native Applications
Architecting Cloud Native ApplicationsArchitecting Cloud Native Applications
Architecting Cloud Native Applications
 
Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...
Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...
Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...
 
FWD Group - Insurer Innovation Award 2024
FWD Group - Insurer Innovation Award 2024FWD Group - Insurer Innovation Award 2024
FWD Group - Insurer Innovation Award 2024
 
Exploring Multimodal Embeddings with Milvus
Exploring Multimodal Embeddings with MilvusExploring Multimodal Embeddings with Milvus
Exploring Multimodal Embeddings with Milvus
 
Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024
Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024
Modular Monolith - a Practical Alternative to Microservices @ Devoxx UK 2024
 
Finding Java's Hidden Performance Traps @ DevoxxUK 2024
Finding Java's Hidden Performance Traps @ DevoxxUK 2024Finding Java's Hidden Performance Traps @ DevoxxUK 2024
Finding Java's Hidden Performance Traps @ DevoxxUK 2024
 
Mcleodganj Call Girls 🥰 8617370543 Service Offer VIP Hot Model
Mcleodganj Call Girls 🥰 8617370543 Service Offer VIP Hot ModelMcleodganj Call Girls 🥰 8617370543 Service Offer VIP Hot Model
Mcleodganj Call Girls 🥰 8617370543 Service Offer VIP Hot Model
 
Introduction to Multilingual Retrieval Augmented Generation (RAG)
Introduction to Multilingual Retrieval Augmented Generation (RAG)Introduction to Multilingual Retrieval Augmented Generation (RAG)
Introduction to Multilingual Retrieval Augmented Generation (RAG)
 
TrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
TrustArc Webinar - Unlock the Power of AI-Driven Data DiscoveryTrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
TrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
 
Six Myths about Ontologies: The Basics of Formal Ontology
Six Myths about Ontologies: The Basics of Formal OntologySix Myths about Ontologies: The Basics of Formal Ontology
Six Myths about Ontologies: The Basics of Formal Ontology
 
Understanding the FAA Part 107 License ..
Understanding the FAA Part 107 License ..Understanding the FAA Part 107 License ..
Understanding the FAA Part 107 License ..
 
Web Form Automation for Bonterra Impact Management (fka Social Solutions Apri...
Web Form Automation for Bonterra Impact Management (fka Social Solutions Apri...Web Form Automation for Bonterra Impact Management (fka Social Solutions Apri...
Web Form Automation for Bonterra Impact Management (fka Social Solutions Apri...
 
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
 
ICT role in 21st century education and its challenges
ICT role in 21st century education and its challengesICT role in 21st century education and its challenges
ICT role in 21st century education and its challenges
 
Repurposing LNG terminals for Hydrogen Ammonia: Feasibility and Cost Saving
Repurposing LNG terminals for Hydrogen Ammonia: Feasibility and Cost SavingRepurposing LNG terminals for Hydrogen Ammonia: Feasibility and Cost Saving
Repurposing LNG terminals for Hydrogen Ammonia: Feasibility and Cost Saving
 
MINDCTI Revenue Release Quarter One 2024
MINDCTI Revenue Release Quarter One 2024MINDCTI Revenue Release Quarter One 2024
MINDCTI Revenue Release Quarter One 2024
 

Optomechanical measurement and FE modeling of tympanic membrane mechanics