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MATERNAL DEATH
REVIEW
Evelina Rosario – Castro, MD, FPOGS,
FPSUOG, FPCS

24 October 2013
How to tell if it is
true contractions…
TRUE LABOR

FALSE LABOR or
BRAXTON HICKS
CONTRACTIONS

O Come every few minutes

O Come every few

and get more frequent
over time.
O Don’t go away, even
when you rest.
O Get stronger and more
painful over time.

minutes, but they don’t
get more frequent over
time.
O Usually go away when
you rest.
O Usually don’t get
stronger or more painful
over time
Determination of AOG and EDC
1.

2.

If discrepancy of
sonar aging and
menstrual date is
7 days or less
If discrepancy is
more than 7 days

1.

Follow menstrual
age all throughout
pregnancy.

2.

USE sonar age all
throughout
pregnancy.*

* EDC that has been set early on should not be changed
based on subsequent scans done in the 2nd and 3rd trimester.
Acceptable Error of Aging
O 12 – 20 weeks:

+/- 7

days
O 24 – 28 weeks :

+/- 14

days
O > 29 weeks:

+/- 21 days
What happens during the
first prenatal visit?
O Ask about:
O health and medical history
O figure out EDC

O Do a complete physical examination
O Include: speculum and internal examination
What happens during the
first prenatal visit?
O History
O Personal and demographic information
O Past obstetrical history
O Personal and family medical history
O Past surgical history
O Genetic history
O Menstrual and gynecological history
O Current pregnancy history
O Psychosocial information
What happens during the
first prenatal visit?
O Estimated date of delivery
O A tentative estimated date of delivery (EDD) can be calculated
from the menstrual history in women with 28-day cycles by:
ONAEGELE’S RULE:

ADD 7 days to the first day of the last menstrual period (LMP) and
then SUBTRACTING 3 months
Example:
1)
2)

LMP: February 20th
EDD: November 27th
LMP: May 28th
EDD: March 4th
What happens during the
first prenatal visit?
O Physical examination
O blood pressure
O Weight and height
O Calculating body mass index (BMI) helps to identify at

risk populations and enables counseling of the amount
of appropriate weight gain in pregnancy.
O Assess uterine size and shape and evaluation of the
adnexa
O uterine fibroids, uterine malposition (eg, retroverted uterus),

multiple gestation, and incorrect date of LMP
What happens during the
first prenatal visit?
O LABORATORY TESTS
O Routine
O Rhesus type and antibody screen — This test will
detect antibodies potentially causing hemolytic disease of the
newborn.
O Hematocrit or hemoglobin and mean corpuscular

volume — detect anemia and provide screening for
thalassemia
- An MCV <80 femtoliters (fL) in the absence of iron
deficiency suggests thalassemia; further testing with
hemoglobin electrophoresis is indicated
What happens during the
first prenatal visit?
O Cervical cytology cancer screening
O 21 years or older who are due for screening according

to standard guidelines
O Pregnancy is not an indication for a change in the
frequency of cervical cancer screening, but
management of an abnormal test is different for
pregnant women
O Rubella immunity
O If nonimmune, the patient should be counseled to

avoid exposure to individuals with rubella and receive
postpartum immunization.
What happens during the
first prenatal visit?
O Varicella immunity
O Women who do not have evidence of immunity to

varicella should be counseled to avoid exposure to
individuals with varicella, may be candidates for
passive immunization during pregnancy if exposed to
varicella, and are candidates for varicella vaccine
postpartum
O Urine protein
O useful as a baseline for comparison if assessment of

renal function is performed later in pregnancy.
What happens during the
first prenatal visit?
O Urine culture
O Routine urine culture is recommended because

pregnant women with untreated asymptomatic
bacteriuria (ASB) are at high risk of developing
pyelonephritis and rapid tests for bacteriuria do not
have adequate sensitivity and specificity
O For women with ASB:
O retesting monthly until delivery, or
O giving suppressive therapy for the remainder of

pregnancy if they have recurrent or persistent bacteriuria.
What happens during the
first prenatal visit?
O Syphilis testing
O Hepatitis B antigen testing
O Chlamydia testing
O Human immunodeficiency virus
What will happen at each
prenatal visit?
O Ask symptoms and answer any questions

of patient
O Ask about fetal movement
O Check :
O BP

O Weight
O Fundic height
O FHT (heard at about 12 weeks of pregnancy)
O Fetal position (Leopold’s Maneuver)
O Test your urine to check for sugar or protein
Schedule of Visits
O Every 4 weeks until about 28 weeks AOG
O Every 2 to 3 weeks until 36 weeks AOG
O Every week until delivery
FOLLOW-UP VISITS
O

Routine assessments at each prenatal visit typically
consist of:
O Measurement of maternal blood pressure and weight
O Urine dipstick for protein (although the value of this test is
O
O
O
O

questionable in women with normal blood pressure)
Measurement of the uterine size or fundal height to
assess fetal growth
Documentation of fetal cardiac activity
Assessment of maternal perception of fetal activity (in the
second and third trimesters)
Assessment of fetal presentation (in the third trimester)
First Trimester
O First trimester screening and diagnostic

testing may include tests for:
O Red cell antibodies
O Current or past infection (eg, sexually transmitted
O
O
O
O

diseases, bacteriuria, rubella immunity)
Inherited disorders (eg, cystic fibrosis, fragile X, spinal
muscular atrophy, hemoglobinopathy)
Fetal aneuploidy (eg, trisomy 21)
Thyroid disease
Lead
15 - 22 weeks AOG
O Neural tube defects
O maternal serum alpha-fetoprotein
O Ultrasound

O Trisomy 21
O 2nd trimester: quadruple test ( ie, level of alpha-

fetoprotein (AFP), unconjugated estriol (uE3), hCG,
and inhibin A in maternal serum)
15 - 22 weeks AOG
O Fetal anomalies
O between 18 and 22 weeks of gestation
O additional testing may be needed to confirm the

suspected diagnosis
O Cervical length
O TVUS measurement of short cervical length between

16 to 28 weeks of gestation is associated with an
increased risk of spontaneous preterm birth <35
weeks.
24 - 28 weeks AOG
O Gestational diabetes
O universal screening for gestational diabetes is recommended

at 24 to 28 weeks of gestation (in the US)
O Screening considered in the first trimester in women with
significant risk factors (eg, body mass index
>30 kg/m2, gestational diabetes or baby >4500 g in a
prior pregnancy, family history of diabetes in a first degree
relative)

O RBC antibodies —
O In Rh(D)-negative women, red cell (RBC) antibody screening

is repeated at 28 weeks of gestation and anti-D immune
globulin is administered.
24 - 28 weeks AOG
O Hemoglobin or hematocrit
O To assess for anemia

The Centers for Disease
Control and Prevention (CDC)

The World Health Organization
(WHO)

1 ST
TRIMESTER

Hgb: < 11 g/dL
Hct: < 33%

Anemia

Hgb: < 11 g/dL
Hct: < 33%

2 ND
TRIMESTER

Hgb: < 10.5 g/dL
Hct: < 32%

Severe
Anemia

Hgb: < 7 g/dL
Hct: < 33%

requires medical
treatment

3 RD
TRIMESTER

Hgb: < 11 g /dL
Hct: < 33%

Very
Severe
Anemia

Hgb: < 4 g/dL
Hct: < 33%

medical
emergency due
to the risk of
congestive heart
failure
28 - 36 weeks AOG
O Sexually transmitted disease (STD)
O The CDC recommends testing for STD (eg, HIV, syphilis,
hepatitis B surface antigen, chlamydia, gonorrhea) in women
O Were diagnosed with a STD earlier in pregnancy

who:

O Continue to have risk factors for acquiring a STD
O Acquired a new risk factor during pregnancy (eg, a new or

more than one sex partner, evaluation or treatment for a
STD, injection of nonprescription drugs)
O All women ≤25 years of age be retested for Chlamydia
trachomatis late in pregnancy
28 - 36 weeks AOG
O Group B beta-hemolytic

streptococcus testing
O 35 to 37 weeks of gestation
O colonization with swabs of both the lower

vagina and rectum
O Excluded from screening:
O (+) GBS bacteriuria earlier in the current

pregnancy
O those who gave birth to a previous infant with
invasive GBS disease.
28 - 36 weeks AOG
O Group B beta-hemolytic

streptococcus testing
O Those excluded from screening should receive

intrapartum antibiotic prophylaxis regardless of
the colonization status.
O Intrapartum chemoprophylaxis of colonized
women has been proven to reduce the incidence
of early-onset neonatal GBS.
28 - 36 weeks AOG
O Estimated fetal weight
O Fetal assessment
O High risk of fetal hypoxemia/acidosis.
O ≥28 weeks of gestation, but may be initiated earlier if

the fetus is believed to be at increased risk of death
and delivery or another intervention is an option.

O External cephalic version
O 36 weeks of gestation or earlier (34 to 35 weeks) to
improve the success rate
37 - 41 weeks AOG
O Patient education in preparation for

labor and delivery
O Management of and support during labor
O Route of delivery
O Induction of labor
O Postterm pregnancy
O For women ≥41 weeks of gestation, we suggest induction

rather than expectant management
How to compute for Ocytocin drip
OStep 1:

Determine the concentration of
oxytocin/mL:
1 unit = 1,000 miliunits (mU)
10 units = 10,000 miliunits (mU)

10,000 mU = 10 mU (10 mU/1 mL)
1,000 mL
1mL
OR
= 1mU / 0.1 mL

OStep 2:

Calculate (at this
concentration) how many mL/hour will
be given:
1 mU/minute = 60 mU/hour
(1 mU X
60mins/hour)

OStep 3: Using ratio & proportion to

calculate mL/hour:
10 mU:1 mL = 60 mU: X mL
10X = 60
X = 6 mL/hour
Friedman’s Curve
1

2

L.T.

No
(intact)

7:56pm

4:35 pm

4:35 pm

WHO Partograph
Precipitate Labor and Delivery
O refers to a rapid labor and delivery of the

fetus
O defined as expulsion of the fetus within 2 –
3 hours of commencement of contractions
Maternal Death Review
Maternal Death Review
Maternal Death Review
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Maternal Death Review

  • 1. MATERNAL DEATH REVIEW Evelina Rosario – Castro, MD, FPOGS, FPSUOG, FPCS 24 October 2013
  • 2. How to tell if it is true contractions… TRUE LABOR FALSE LABOR or BRAXTON HICKS CONTRACTIONS O Come every few minutes O Come every few and get more frequent over time. O Don’t go away, even when you rest. O Get stronger and more painful over time. minutes, but they don’t get more frequent over time. O Usually go away when you rest. O Usually don’t get stronger or more painful over time
  • 3. Determination of AOG and EDC 1. 2. If discrepancy of sonar aging and menstrual date is 7 days or less If discrepancy is more than 7 days 1. Follow menstrual age all throughout pregnancy. 2. USE sonar age all throughout pregnancy.* * EDC that has been set early on should not be changed based on subsequent scans done in the 2nd and 3rd trimester.
  • 4. Acceptable Error of Aging O 12 – 20 weeks: +/- 7 days O 24 – 28 weeks : +/- 14 days O > 29 weeks: +/- 21 days
  • 5. What happens during the first prenatal visit? O Ask about: O health and medical history O figure out EDC O Do a complete physical examination O Include: speculum and internal examination
  • 6. What happens during the first prenatal visit? O History O Personal and demographic information O Past obstetrical history O Personal and family medical history O Past surgical history O Genetic history O Menstrual and gynecological history O Current pregnancy history O Psychosocial information
  • 7. What happens during the first prenatal visit? O Estimated date of delivery O A tentative estimated date of delivery (EDD) can be calculated from the menstrual history in women with 28-day cycles by: ONAEGELE’S RULE: ADD 7 days to the first day of the last menstrual period (LMP) and then SUBTRACTING 3 months Example: 1) 2) LMP: February 20th EDD: November 27th LMP: May 28th EDD: March 4th
  • 8. What happens during the first prenatal visit? O Physical examination O blood pressure O Weight and height O Calculating body mass index (BMI) helps to identify at risk populations and enables counseling of the amount of appropriate weight gain in pregnancy. O Assess uterine size and shape and evaluation of the adnexa O uterine fibroids, uterine malposition (eg, retroverted uterus), multiple gestation, and incorrect date of LMP
  • 9. What happens during the first prenatal visit? O LABORATORY TESTS O Routine O Rhesus type and antibody screen — This test will detect antibodies potentially causing hemolytic disease of the newborn. O Hematocrit or hemoglobin and mean corpuscular volume — detect anemia and provide screening for thalassemia - An MCV <80 femtoliters (fL) in the absence of iron deficiency suggests thalassemia; further testing with hemoglobin electrophoresis is indicated
  • 10. What happens during the first prenatal visit? O Cervical cytology cancer screening O 21 years or older who are due for screening according to standard guidelines O Pregnancy is not an indication for a change in the frequency of cervical cancer screening, but management of an abnormal test is different for pregnant women O Rubella immunity O If nonimmune, the patient should be counseled to avoid exposure to individuals with rubella and receive postpartum immunization.
  • 11. What happens during the first prenatal visit? O Varicella immunity O Women who do not have evidence of immunity to varicella should be counseled to avoid exposure to individuals with varicella, may be candidates for passive immunization during pregnancy if exposed to varicella, and are candidates for varicella vaccine postpartum O Urine protein O useful as a baseline for comparison if assessment of renal function is performed later in pregnancy.
  • 12. What happens during the first prenatal visit? O Urine culture O Routine urine culture is recommended because pregnant women with untreated asymptomatic bacteriuria (ASB) are at high risk of developing pyelonephritis and rapid tests for bacteriuria do not have adequate sensitivity and specificity O For women with ASB: O retesting monthly until delivery, or O giving suppressive therapy for the remainder of pregnancy if they have recurrent or persistent bacteriuria.
  • 13. What happens during the first prenatal visit? O Syphilis testing O Hepatitis B antigen testing O Chlamydia testing O Human immunodeficiency virus
  • 14. What will happen at each prenatal visit? O Ask symptoms and answer any questions of patient O Ask about fetal movement O Check : O BP O Weight O Fundic height O FHT (heard at about 12 weeks of pregnancy) O Fetal position (Leopold’s Maneuver) O Test your urine to check for sugar or protein
  • 15. Schedule of Visits O Every 4 weeks until about 28 weeks AOG O Every 2 to 3 weeks until 36 weeks AOG O Every week until delivery
  • 16. FOLLOW-UP VISITS O Routine assessments at each prenatal visit typically consist of: O Measurement of maternal blood pressure and weight O Urine dipstick for protein (although the value of this test is O O O O questionable in women with normal blood pressure) Measurement of the uterine size or fundal height to assess fetal growth Documentation of fetal cardiac activity Assessment of maternal perception of fetal activity (in the second and third trimesters) Assessment of fetal presentation (in the third trimester)
  • 17. First Trimester O First trimester screening and diagnostic testing may include tests for: O Red cell antibodies O Current or past infection (eg, sexually transmitted O O O O diseases, bacteriuria, rubella immunity) Inherited disorders (eg, cystic fibrosis, fragile X, spinal muscular atrophy, hemoglobinopathy) Fetal aneuploidy (eg, trisomy 21) Thyroid disease Lead
  • 18. 15 - 22 weeks AOG O Neural tube defects O maternal serum alpha-fetoprotein O Ultrasound O Trisomy 21 O 2nd trimester: quadruple test ( ie, level of alpha- fetoprotein (AFP), unconjugated estriol (uE3), hCG, and inhibin A in maternal serum)
  • 19. 15 - 22 weeks AOG O Fetal anomalies O between 18 and 22 weeks of gestation O additional testing may be needed to confirm the suspected diagnosis O Cervical length O TVUS measurement of short cervical length between 16 to 28 weeks of gestation is associated with an increased risk of spontaneous preterm birth <35 weeks.
  • 20. 24 - 28 weeks AOG O Gestational diabetes O universal screening for gestational diabetes is recommended at 24 to 28 weeks of gestation (in the US) O Screening considered in the first trimester in women with significant risk factors (eg, body mass index >30 kg/m2, gestational diabetes or baby >4500 g in a prior pregnancy, family history of diabetes in a first degree relative) O RBC antibodies — O In Rh(D)-negative women, red cell (RBC) antibody screening is repeated at 28 weeks of gestation and anti-D immune globulin is administered.
  • 21. 24 - 28 weeks AOG O Hemoglobin or hematocrit O To assess for anemia The Centers for Disease Control and Prevention (CDC) The World Health Organization (WHO) 1 ST TRIMESTER Hgb: < 11 g/dL Hct: < 33% Anemia Hgb: < 11 g/dL Hct: < 33% 2 ND TRIMESTER Hgb: < 10.5 g/dL Hct: < 32% Severe Anemia Hgb: < 7 g/dL Hct: < 33% requires medical treatment 3 RD TRIMESTER Hgb: < 11 g /dL Hct: < 33% Very Severe Anemia Hgb: < 4 g/dL Hct: < 33% medical emergency due to the risk of congestive heart failure
  • 22. 28 - 36 weeks AOG O Sexually transmitted disease (STD) O The CDC recommends testing for STD (eg, HIV, syphilis, hepatitis B surface antigen, chlamydia, gonorrhea) in women O Were diagnosed with a STD earlier in pregnancy who: O Continue to have risk factors for acquiring a STD O Acquired a new risk factor during pregnancy (eg, a new or more than one sex partner, evaluation or treatment for a STD, injection of nonprescription drugs) O All women ≤25 years of age be retested for Chlamydia trachomatis late in pregnancy
  • 23. 28 - 36 weeks AOG O Group B beta-hemolytic streptococcus testing O 35 to 37 weeks of gestation O colonization with swabs of both the lower vagina and rectum O Excluded from screening: O (+) GBS bacteriuria earlier in the current pregnancy O those who gave birth to a previous infant with invasive GBS disease.
  • 24. 28 - 36 weeks AOG O Group B beta-hemolytic streptococcus testing O Those excluded from screening should receive intrapartum antibiotic prophylaxis regardless of the colonization status. O Intrapartum chemoprophylaxis of colonized women has been proven to reduce the incidence of early-onset neonatal GBS.
  • 25. 28 - 36 weeks AOG O Estimated fetal weight O Fetal assessment O High risk of fetal hypoxemia/acidosis. O ≥28 weeks of gestation, but may be initiated earlier if the fetus is believed to be at increased risk of death and delivery or another intervention is an option. O External cephalic version O 36 weeks of gestation or earlier (34 to 35 weeks) to improve the success rate
  • 26. 37 - 41 weeks AOG O Patient education in preparation for labor and delivery O Management of and support during labor O Route of delivery O Induction of labor O Postterm pregnancy O For women ≥41 weeks of gestation, we suggest induction rather than expectant management
  • 27.
  • 28. How to compute for Ocytocin drip OStep 1: Determine the concentration of oxytocin/mL: 1 unit = 1,000 miliunits (mU) 10 units = 10,000 miliunits (mU) 10,000 mU = 10 mU (10 mU/1 mL) 1,000 mL 1mL OR = 1mU / 0.1 mL OStep 2: Calculate (at this concentration) how many mL/hour will be given: 1 mU/minute = 60 mU/hour (1 mU X 60mins/hour) OStep 3: Using ratio & proportion to calculate mL/hour: 10 mU:1 mL = 60 mU: X mL 10X = 60 X = 6 mL/hour
  • 29.
  • 32. Precipitate Labor and Delivery O refers to a rapid labor and delivery of the fetus O defined as expulsion of the fetus within 2 – 3 hours of commencement of contractions

Notes de l'éditeur

  1. Rh(D)-negative women without alloantibodies should receive anti(D)-immune globulin, as indicated.
  2. Rh(D)-negative women without alloantibodies should receive anti(D)-immune globulin, as indicated.
  3. Rh(D)-negative women without alloantibodies should receive anti(D)-immune globulin, as indicated.
  4. Rh(D)-negative women without alloantibodies should receive anti(D)-immune globulin, as indicated.
  5. Rh(D)-negative women without alloantibodies should receive anti(D)-immune globulin, as indicated.
  6. Leda explains it well. Use that to explain to new nurses what the concentration is. If you have 10,000mU in 1000ml, you have 10mU in 1ml or 1mU in 0.1ml. If you have 20,000mU in 1000ml, you have 20mU in 1ml or 2mU in 0.1ml or 1mU in 0.05ml.I got all this, but it took me forever to figure out where the 6 came in. It come in because there are 60 min in an hour and you program the pump in ml/hr even though the dose is given in mU/min. If you want 1mU/min, you want 60mU/hr. Sixty mU is contained in 6ml of 10U/1000ml solution or 3ml of the 20U/1000ml solution. The difficulty of figuring this out at 3am, or even remembering the 6X table at that hour of the morning is why it is recommended by various authors to use a 30U/500ml concentration. Work it out and you&apos;ll see why it&apos;s a much safer concentration to use.