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KWASHIORKOR Presenters: Kasturi Mahalinggam ( 060100293)Siti Raihana (060100246)Supervisor: dr. Oke Rina Ramayani Sp.A
Definition of Kwashiorkor "Kwashiorkor" is the name given to the protein-calorie malnutrition. It is a Ga word which describes the malnourished child, the result of the ill-health which develops when an infant is weaned from breast-feeding (which may be at about 2 years of age).  When a sibling is born and monopolizes breast feeding, the "weaning" or deposed child may develop kwashiorkor, an all-embracing word for the clinical syndrome of malnourishment in which reddening of the child's hair is but a part.
EPIDEMIOLOGY… ,[object Object]
 Approximately 80%of these malnourished children live in Asia,   15% in Africa, and 5% in Latin America.   MORTALITY/MORBIDITY… ,[object Object],  of malnutrition.  ,[object Object],  with some stunting
Causes Social and Economic Poverty Ignorance Inadequate weaning practices Child abuse Cultural and social practices Vegan Low fat diets
Sign & Symptom
Pathophysiology Peripheral oedema ,[object Object],[object Object]
therefore unused lipids which would normally participate inlipoproteinsynthesis begin to accumulate. ,[object Object]
When the liver cells are damaged, the immune system of the body respond to this damage and causes inflammation inside the liver which will cause the liver to enlarge in size. This is then known as Steatohepatitis.
 Damage to the liver cells or the liver cells dying off can decrease the functions the liver is able to do to keep the body well. One of these functions is to produce proteins. Therefore, it also leads to a decrease in albumin levels, which leads to this build up of abdominal fluid.,[object Object]
TREATMENT… 10 steps for routine management of children with malnutrition Prevent and treat the following: Hypoglycemia Hypothermia Dehydration Electrolyte imbalance Infection Micronutrient deficiencies Provide special feeds for the following: Initial stabilization  Catch-up growth  Provide loving care and stimulation Prepare for follow-up after discharge
Case Report MF, was admitted to RSUP HAM on April 13th 2010 at 1500. 1 year old BW : 9.8 kg height  : 70 cm Complaint : Oedemat the body with dermatosis mostly at lower extremities and some part of his body experience for the last 2 weeks.  At first, oedem start at his face genital all of his body.  Fever  in last 2 days. Cough (-), flu (-). History of oedem (-) Defecation and urination : Normal. History of delivery ; spontaneous, aided by midwife, BW : 2800 gram, BL : unknown, crying, cyanosis (-).  History of immunization : complete, BCG scar (+).  History of feeding ;  	0- week 1 		: breast milk, 	week 1 – 2 month 	: SGM 30 cc, 6-7 times/day. 	2 month-7 month	: SGM + Promina.  	7 month- 13 month 	: porridge 3 times/day volume half bowl.  	13 month till now 	: rice.  History of disease : (-) 
Physical Examination :
Treatment Diet F75 125 cc/3 hours/oral. Zinc 1x20mg. Folic acid 1x1 mg Multivitamin without Ferum 1x1 Vitamin A 200000 IU
Follow : April 14-18th 2010
Laboratory Result : (April 15th 2010) Liver: Total Bilirubin	: 0.41 mg/dL 	(<1) Direct Bilirubin	:  1.32 mg/dL 	(0-0.2)   	   	Alkaline Phosphatase: 133 U/L 	(<449) SGOT/AST	: 68 U/L 	(<38)   	   	SGPT/ALT	:34 U/L 		(<41) Albumin	: 1.4 g/dl 			(3.8-5.4)   Kidney	: Ureum		: 12 mg/dL (<50) Creatine	: 0.24 mg/dL (0.17-0.42) 		  Uric acid	: 1.4 mg/dL (<7.0)  
Hematology Hemoglobin	: 9.36 g% 			(10.7-17.1) Erythrocyte	: 3.55 106/mm3 			(3.75-4.95) Leukocyte	: 26.80 103/mm3 			(6.0-17.5) Hematocryte	: 28.40 % 			(38-52) Thrombocyte	: 129 103/mm3 			(217-497) Neutrophil	: 28.50 % 				(37-80) Lymphocyte	: 63.50 %			(20-40) Monocyte	: 6.41 % 				(2-8) Eosinophil	: 0.19 					(1-6) Basophil	: 1.41 % 				(0-1) Neutrophil Absolute	: 7.36 103/µL 		(1.9-5.4) Lymphocyte Absolute	: 17 103/µL 		(3.7-10.7) Monocyte Absolute	: 1.72 103/µL 		(0.3-0.8) Eosinophil Absolute	: 0.050 103/µL 		(0.2-0.5)  Basophil Absolute	: 0.377 103/µL 			(0-0.1)
Follow : April 19 & 21-23th 2010
Follow : April 20th 2010
Follow : April 24th - Mei 2nd 2010
Follow : Mei 3 – 5th  2010
DISCUSSION
SUMMARY It has been reported that an 1 year old baby boy with his chief complaint of oedem all over his body. He has been diagnosed with severe malnutrition kwashiorkor type based on the history taking, physical examinations and laboratory results.

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Kwashiorkor

  • 1. KWASHIORKOR Presenters: Kasturi Mahalinggam ( 060100293)Siti Raihana (060100246)Supervisor: dr. Oke Rina Ramayani Sp.A
  • 2.
  • 3.
  • 4. Definition of Kwashiorkor "Kwashiorkor" is the name given to the protein-calorie malnutrition. It is a Ga word which describes the malnourished child, the result of the ill-health which develops when an infant is weaned from breast-feeding (which may be at about 2 years of age). When a sibling is born and monopolizes breast feeding, the "weaning" or deposed child may develop kwashiorkor, an all-embracing word for the clinical syndrome of malnourishment in which reddening of the child's hair is but a part.
  • 5.
  • 6.
  • 7. Causes Social and Economic Poverty Ignorance Inadequate weaning practices Child abuse Cultural and social practices Vegan Low fat diets
  • 8.
  • 10.
  • 11.
  • 12. When the liver cells are damaged, the immune system of the body respond to this damage and causes inflammation inside the liver which will cause the liver to enlarge in size. This is then known as Steatohepatitis.
  • 13.
  • 14. TREATMENT… 10 steps for routine management of children with malnutrition Prevent and treat the following: Hypoglycemia Hypothermia Dehydration Electrolyte imbalance Infection Micronutrient deficiencies Provide special feeds for the following: Initial stabilization Catch-up growth Provide loving care and stimulation Prepare for follow-up after discharge
  • 15.
  • 16. Case Report MF, was admitted to RSUP HAM on April 13th 2010 at 1500. 1 year old BW : 9.8 kg height : 70 cm Complaint : Oedemat the body with dermatosis mostly at lower extremities and some part of his body experience for the last 2 weeks. At first, oedem start at his face genital all of his body. Fever in last 2 days. Cough (-), flu (-). History of oedem (-) Defecation and urination : Normal. History of delivery ; spontaneous, aided by midwife, BW : 2800 gram, BL : unknown, crying, cyanosis (-). History of immunization : complete, BCG scar (+). History of feeding ; 0- week 1 : breast milk, week 1 – 2 month : SGM 30 cc, 6-7 times/day. 2 month-7 month : SGM + Promina. 7 month- 13 month : porridge 3 times/day volume half bowl. 13 month till now : rice. History of disease : (-) 
  • 18. Treatment Diet F75 125 cc/3 hours/oral. Zinc 1x20mg. Folic acid 1x1 mg Multivitamin without Ferum 1x1 Vitamin A 200000 IU
  • 19. Follow : April 14-18th 2010
  • 20. Laboratory Result : (April 15th 2010) Liver: Total Bilirubin : 0.41 mg/dL (<1) Direct Bilirubin : 1.32 mg/dL (0-0.2) Alkaline Phosphatase: 133 U/L (<449) SGOT/AST : 68 U/L (<38) SGPT/ALT :34 U/L (<41) Albumin : 1.4 g/dl (3.8-5.4)   Kidney : Ureum : 12 mg/dL (<50) Creatine : 0.24 mg/dL (0.17-0.42) Uric acid : 1.4 mg/dL (<7.0)  
  • 21. Hematology Hemoglobin : 9.36 g% (10.7-17.1) Erythrocyte : 3.55 106/mm3 (3.75-4.95) Leukocyte : 26.80 103/mm3 (6.0-17.5) Hematocryte : 28.40 % (38-52) Thrombocyte : 129 103/mm3 (217-497) Neutrophil : 28.50 % (37-80) Lymphocyte : 63.50 % (20-40) Monocyte : 6.41 % (2-8) Eosinophil : 0.19 (1-6) Basophil : 1.41 % (0-1) Neutrophil Absolute : 7.36 103/µL (1.9-5.4) Lymphocyte Absolute : 17 103/µL (3.7-10.7) Monocyte Absolute : 1.72 103/µL (0.3-0.8) Eosinophil Absolute : 0.050 103/µL (0.2-0.5) Basophil Absolute : 0.377 103/µL (0-0.1)
  • 22. Follow : April 19 & 21-23th 2010
  • 23.
  • 24. Follow : April 20th 2010
  • 25.
  • 26. Follow : April 24th - Mei 2nd 2010
  • 27. Follow : Mei 3 – 5th 2010
  • 29.
  • 30. SUMMARY It has been reported that an 1 year old baby boy with his chief complaint of oedem all over his body. He has been diagnosed with severe malnutrition kwashiorkor type based on the history taking, physical examinations and laboratory results.
  • 31. Thank You