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Ishita Moghe and Kim Solez, MD
Technology & Future of Medicine LABMP
590 Course at Univ. Alberta Since 2011
Banff Transplant Path. Classification
and Consensus Meetings Since 1991
Banff Foundation Since 2013
Banff Classification of Kidney Transplant Pathology
Histologic criteria for the diagnosis of rejection and
other conditions in the transplanted kidney, began
1991, updated and expanded every two years in
consensus meeting.
New Banff Classification of Tissue
Engineering Pathology: Am. Journal of
Transplantation February 2018
Tissue Engineering Pathology: Getting
the Right Cells in the Right Places in
Bioengineered Organs
Tissue Engineering Pathology: Getting
the Right Cells in the Right Places in
Bioengineered Organs
Something Missing In the Concept of
Tissue Engineering Pathology: The
Numbers – How Many Cells Types?
Human Cell Atlas Begins to Answer
This: Was thought there were 300+
Main Cell Types in Human Body – 26
in Kidney (Al-Awqati and Oliver,2002)
Human Cell Atlas Begins to Answer
This: Studies in dendritic cells
suggest number of cell types will at
least double through HCAP analysis,
kidney cell types will go from 26-52.
So the Hitchhikers Guide to the
Galaxy is Off by Ten, the Meaning of
Life, the Universe, and Everything is
52 not 42
Human Cell Atlas: 300+ Main Cell
Types in Human Body – 1000s of
subtypes
Human Cell Atlas Begins to Answer
This Numbers Question: Analysis is
Inexpensive and Fast
Human Cell Atlas Begins to Answer
This Numbers Question: Analysis is
Inexpensive and Fast
Human Cell Atlas Already Leading to
Disease Insights Variants, Acting on
Them = Pathology
Human Cell Atlas Already Leading to
Disease Insights Variants, Acting on
Them = Pathology
Human Cell Atlas Will Revolutionize
Urinalysis and Renal Biopsy
Interpretation. In Urinalysis the First
Major Advance in 6000 years!
Human Cell Atlas Pace of Change
Considerably Exceeds Moore’s Law
Human Cell Atlas Pace of Change
Considerably Exceeds Moore’s Law
Human Cell Atlas Pace of Change
Considerably Exceeds Moore’s Law
Human Cell Atlas Pace of Change
Considerably Exceeds Moore’s Law
What You Can Do to Promote and
Strengthen the Human Cell Atlas
Project and Regenerative Medicine
 Insist on inclusion of Human Cell Atlas and
Regenerative Medicine in Global Summit
papers and position papers.
 Insist on inclusion of Human Cell Atlas and
Regenerative Medicine presentations in major
meetings currently silent on these issues.
 Stay for all of Human Cell Atlas & Regenerative
Medicine meetings. No more parachuting in.
Make these important meetings mainstream!
What You Can Do to Promote and
Strengthen the Human Cell Atlas
Project and Regenerative Medicine
 Insist on inclusion of Human Cell Atlas and
Regenerative Medicine in Global Summit
papers and position papers. The recent global
kidney health summit articles from Oct. 2017
in Lancet and KI are completely silent on
human cell atlas, regenerative medicine, tissue
engineering, ex vivo perfusion, artificial
intelligence, artificial
organs, and
xenotransplantation!
What You Can Do to Promote and
Strengthen the Human Cell Atlas
Project and Regenerative Medicine
 Insist on inclusion of Human Cell Atlas and
presentations in major meetings currently
silent on this issue. Last year the USCAP and
American Transplant Congress had nothing
about the Human Cell Atlas Project on the
program. If this continues the whole
community will be blindsided!
What You Can Do to Promote and
Strengthen the Human Cell Atlas
Project and Regenerative Medicine
 Stay for all of Human Cell Atlas & Regenerative
Medicine meetings. No more parachuting in.
Make these important meetings mainstream!
Human Cell Atlas and Human
Centered Design
Human Cell Atlas and Human
Centered Computing
Human Cell Atlas & Human Centered
Computing – Expandable Nature of
Time – Kim Solez/Elon Musk
Human Cell Atlas and Human
Centered Computing – Multitasking
Human Cell Atlas and World Future
2018: Human Purpose (Chicago
August 16-17, 2018)
Kim Solez Ishita Moghe Human cell atlas what you can do to promote it in context of word future 2018 human purpose 2

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Kim Solez Ishita Moghe Human cell atlas what you can do to promote it in context of word future 2018 human purpose 2

  • 1. Ishita Moghe and Kim Solez, MD
  • 2. Technology & Future of Medicine LABMP 590 Course at Univ. Alberta Since 2011
  • 3. Banff Transplant Path. Classification and Consensus Meetings Since 1991 Banff Foundation Since 2013
  • 4. Banff Classification of Kidney Transplant Pathology Histologic criteria for the diagnosis of rejection and other conditions in the transplanted kidney, began 1991, updated and expanded every two years in consensus meeting.
  • 5. New Banff Classification of Tissue Engineering Pathology: Am. Journal of Transplantation February 2018
  • 6. Tissue Engineering Pathology: Getting the Right Cells in the Right Places in Bioengineered Organs
  • 7. Tissue Engineering Pathology: Getting the Right Cells in the Right Places in Bioengineered Organs
  • 8. Something Missing In the Concept of Tissue Engineering Pathology: The Numbers – How Many Cells Types?
  • 9. Human Cell Atlas Begins to Answer This: Was thought there were 300+ Main Cell Types in Human Body – 26 in Kidney (Al-Awqati and Oliver,2002)
  • 10. Human Cell Atlas Begins to Answer This: Studies in dendritic cells suggest number of cell types will at least double through HCAP analysis, kidney cell types will go from 26-52.
  • 11. So the Hitchhikers Guide to the Galaxy is Off by Ten, the Meaning of Life, the Universe, and Everything is 52 not 42
  • 12. Human Cell Atlas: 300+ Main Cell Types in Human Body – 1000s of subtypes
  • 13. Human Cell Atlas Begins to Answer This Numbers Question: Analysis is Inexpensive and Fast
  • 14. Human Cell Atlas Begins to Answer This Numbers Question: Analysis is Inexpensive and Fast
  • 15. Human Cell Atlas Already Leading to Disease Insights Variants, Acting on Them = Pathology
  • 16. Human Cell Atlas Already Leading to Disease Insights Variants, Acting on Them = Pathology
  • 17. Human Cell Atlas Will Revolutionize Urinalysis and Renal Biopsy Interpretation. In Urinalysis the First Major Advance in 6000 years!
  • 18. Human Cell Atlas Pace of Change Considerably Exceeds Moore’s Law
  • 19. Human Cell Atlas Pace of Change Considerably Exceeds Moore’s Law
  • 20. Human Cell Atlas Pace of Change Considerably Exceeds Moore’s Law
  • 21. Human Cell Atlas Pace of Change Considerably Exceeds Moore’s Law
  • 22. What You Can Do to Promote and Strengthen the Human Cell Atlas Project and Regenerative Medicine  Insist on inclusion of Human Cell Atlas and Regenerative Medicine in Global Summit papers and position papers.  Insist on inclusion of Human Cell Atlas and Regenerative Medicine presentations in major meetings currently silent on these issues.  Stay for all of Human Cell Atlas & Regenerative Medicine meetings. No more parachuting in. Make these important meetings mainstream!
  • 23. What You Can Do to Promote and Strengthen the Human Cell Atlas Project and Regenerative Medicine  Insist on inclusion of Human Cell Atlas and Regenerative Medicine in Global Summit papers and position papers. The recent global kidney health summit articles from Oct. 2017 in Lancet and KI are completely silent on human cell atlas, regenerative medicine, tissue engineering, ex vivo perfusion, artificial intelligence, artificial organs, and xenotransplantation!
  • 24. What You Can Do to Promote and Strengthen the Human Cell Atlas Project and Regenerative Medicine  Insist on inclusion of Human Cell Atlas and presentations in major meetings currently silent on this issue. Last year the USCAP and American Transplant Congress had nothing about the Human Cell Atlas Project on the program. If this continues the whole community will be blindsided!
  • 25. What You Can Do to Promote and Strengthen the Human Cell Atlas Project and Regenerative Medicine  Stay for all of Human Cell Atlas & Regenerative Medicine meetings. No more parachuting in. Make these important meetings mainstream!
  • 26. Human Cell Atlas and Human Centered Design
  • 27. Human Cell Atlas and Human Centered Computing
  • 28. Human Cell Atlas & Human Centered Computing – Expandable Nature of Time – Kim Solez/Elon Musk
  • 29. Human Cell Atlas and Human Centered Computing – Multitasking
  • 30. Human Cell Atlas and World Future 2018: Human Purpose (Chicago August 16-17, 2018)