Fabrice Leclerc

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I developp and apply computational and modeling approaches to understand the structure/function relationships of RNAs at different levels of complexity and representations (sequence, 2D and 3D structure). My research interests include: RNomics (identification and characterization of non-coding RNA genes), computational enzymology (elucidate the catalysis by self-cleaving ribozymes), docking (model and predict RNA/protein interactions). Specialties: RNA, molecular modeling, bioinformatics, theoretical and computational (bio)chemistry, computational biology and RNomics

rna ribozyme catalysis molecular dynamics neutron sans self-assembly viroid origin of life enzymology hammerhead viroids structure/function rna 2d bioinformatics h/aca srna visualization pseudouridylation rnomics trna rrna guide archaea life rna world enzyme

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Fabrice Leclerc

Présentations

Computational Enzymology of Ribozymes (from metal-ion to nucleobase catalysis and back ?)

H/ACA(like) sRNA in Archaea

Visualization of RNA 2D Structures - Structure/function relationships of H/ACA motifs: Analysis & Prediction

Viroids and the RNA World

Self-Assembly & Catalysis by HHR from ASBVd(-)

J’aime

Aptamers based drug delivery

Biochemistry 304 2014 student edition enzymes and enzyme kinetics

Towards a Platform for Global Health

NMR in fragment based drug discovery

Nicole Nogoy at the Auckland BMC RoadShow

2014 CrossRef Annual Meeting Peer Review Panel: bioRxiv: the preprint server for biology

2014 bosc-keynote

StratusLab: A IaaS Cloud Distribution Focusing on Simplicity

The structure of Linux - Introduction to Linux for bioinformatics

Introduction to Linux for bioinformatics

Text mining on the command line - Introduction to linux for bioinformatics

Electronic Lab Notebooks

IDB-Cloud Providing Bioinformatics Services on Cloud

Making the Web work for science - SciTechLA

The Origin Of Life Dual Origin Hypothesis

BFR_Quelques pistes pour remplacer Google Reader

IB Biology Option D.1: Origin of life

Datavisualisation et médiation scientifique

Creating visualizations using Linked Data

What Teachers Think About Web 2.0 Technologies in Education?

Tin-Lap Lee: GDSAP- A Galaxy-based platform for large-scale genomics analysis

If we build it will they come? BOSC2012 Keynote Goble

ISMB2012: The Gene Wiki: Crowdsourcing human gene annotation

ISA Commons / BioSharing - Susanna-Assunta Sansone - ISMB 2012

I want to publish more and read less

Best Practices for Twitter for Healthcare and Pharma Professionals

How and why I use blogging

BITs: Genome browsers and interpretation of gene lists.

Bits protein structure

BITS training - UCSC Genome Browser - Part 2