2. Risk Factors for Adverse Drug Reactions in
the Elderly
Older females are more at risk for adverse drug reactions than males and the
younger population
Drug reactions increase proportionally to the number of drugs taken, older adults
are usually on a lot of prescription drugs which put them at a higher risk.
Hepatic and/or renal insufficiency put the individual at a higher risk for adverse
drug reactions
3. Problematic Drugs for the Older Adult
Problematic Drug Classifications that are most often prescribed the older adult
include:
1. long- acting benzodiazepines
2. Dipyridamole (Persantine)
3. Propozyphene (Darvon)
4. Amitriptyline (Elavil)
4. Polypharmacy
Polypharmacy-
The use of multiple medications at the same time. Prescribing more medication
than what it clinically necessary
5. Characteristics of Older Adults with
Medication Related Problems:
85 years and older
More than 6 active medical diagnoses
Low body weight or decreased body mass index
Impaired kidney function
Taking more than 5 different medications
6. Medication Regimen
You should know:
The route of your medication (Oral, inhaler, Injection)
Appropriate time to take your medication
The dosage of your medication
Any side effects of your medications and when to consult medical attention
Why are you taking this medication?
7. Interactions
Does your medication interact with..
Other medications?
Certain types of foods?
Over the counter medications?
Herbal remedies?
Alcohol?
8. How to keep track of your medications
Pill organizer
Color coding
Lists
Memory devices
Keep an up to date list of all medications you are currently taking.
Always have on hang to show physician
12. Consequences of Inappropriate Drug
Management
FALLS
One-third of older adults fall each year. Falls can lead to substantial consequences
which can most of the time be prevented
Psychotropic drugs and narcotic analgesics are associated with falls because of
their sedating nature and impact on the CNS.
Cardiovascular drugs, especially blood pressure medications, also put a person at
a high risk for falls because of their orthostatic blood pressure changes.
13.
14. Death
Adverse drug reactions may be between the fourth and sixth leading cause of
death in the United States.
15. References
Images received from www.google.com/images
Ainslie, N. (2004) Learning Module Hospice: Polypharmacy Drug Use. Retrieved
from: http://classes.kumc/som/amed900/polypharmcay/polypharmacy-Know.htm
Aparasum, R. & Mort, J.R. (2000). Inappropriate prescribing for the elderly. Annals
of Pharmacotherapeutics, 34, 338-346.
Barat, I. Andreason, F., & Damsgaard, E. (2001). Drug therapy in the elderly. What
doctors believe and patients actually do. British Journal of Clinical Pharmacology,
51, 615-622.