1. NSG 2500: Pharmacology Summer 2011

2. Syllabus

3. Class Resources-Blackboard

4. Class Resources-The Point

5. Class Resources-EDGT

6. What is a Drug?

7. Drug Names Trade Name Generic name Chemical name: methyl 7-((1R,2R)-3-hydroxy-2-((S,E)-4-hydroxy-4-methyloct-1-enyl)-5-oxocyclopentyl)heptanoate

8. Dosage Forms-Oral Tablets Capsules Pills Suspensions Liquids

9. Dosage Forms-IM/SC

10. Dosage Forms-IV (parenteral)

11. Dosage Forms-Sublingual

12. Dosage Forms-Inhalation

13. Dosage Form-Transdermal

14. Dosage Form-Topical

15. Clinical Trials

16. Pregnancy Categories A B C D X The BEST (but there are not many!)

17. Controlled Substances

18. Controlled Substances Narcotics, Amphetamines, Barbiturates, Many drugs used to treat ADD/ADHD

19. Controlled Substances

20. Controlled Substances

21. Controlled Substances

22. Generic Drugs

23. Over the Counter Drugs

24. Over the Counter Drugs

25. Over the Counter Drugs

26. Over the Counter Drugs

27. Over the Counter Drugs

28. Over the Counter Drugs

29. Over the Counter Drugs

30. Sources of Drug Information Drug Facts and Comparisons

31. Sources of Drug Information PDR

32. Sources of Drug Information United States Pharmacopeia, National Formulary

33. Sources of Drug Information Nursing Drug Reference

34. Sources of Drug Information Nursing Journals

35. Sources of Drug Information Reliable Internet Sources

36. Sources of Drug Information Reliable Internet Sources Lexi-Comp through Levin Library or free for a month trial

37. Pharmacology Concepts Pharmacology Drug therapy Pharmacodynamics Drug to Body Pharmacokinetics Absorption First Pass DISTRIBUTION

38. Question: What is an action of a drug? A. To increase enzymatic reactions in the body B. To alter a missing chemical C. To depress or slow cellular activities D. To increase the effect of foreign substances

39. Pharmacology concepts Absorption Distribution Drug Binding Metabolism Excretion

40. Protein Binding

41. Pharmacokinetics Onset ½ life Peak Duration

42. Monitoring Drug Effects Onset, Peak, Duration

43. Factors Influencing Drug Effects:Weight

44. Factors Influencing Drug Effects:Age

45. Factors Influencing Drug Effects: Physiology/Pathophysiology

46. Factors Influencing Drug Effects: Genetics

47. Factors Influencing Drug Effects Immunological Psychologica Environmental Tolerance Cumulative

48. Drug Effects Therapeutic Index

49. Drug Interactions Drug-Drug

50. Drug Interactions Drug-Food

51. Drug Interactions Drug-Herbal

52. Drug Interactions Drug-Lab

53. Adverse Drug Reactions Primary Secondary Hypersensitivity

54. Allergic Reactions Anaphylactic

55. Allergic Reactions Cytotoxic Serum Sickness Delayed Allergic

56. Drug Reactions HIVES-URTICARIA

57. Drug Reactions STOMATITIS

58. Drug Reactions Superinfection (ex: Thrush)

59. Drug Reactions Bone Marrow Suppression

60. Drug Toxicity Kidney Liver

61. Adverse Effects Altered glucose metabolism

62. Adverse Effects Electrolyte imbalance

63. Adverse Effects Sensory effects

64. Adverse Effects Neurological effects

65. Adverse Effects Teratogenicity

66. Nursing Process & Patient Safety

67. Nursing Process

68. Rights of Drug Administration Storage Preparation Recording

69. Promoting Drug Therapy

70. Preventing Medication Errors

71. Preventing Medication Errors

72. Drug information and the public

73. Federal Guidelines:Drug Advertising MUST INCLUDE: Indication—Contraindications--Adverse effects--Precautions

74. Internet sources of drug information Reliable or not????

75. Problems with OTC medications

76. Alternative Therapies

77. Off-label use of medications