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Dr. S. Krishnan 
Associate Professor of Psychiatry 
Government Medical College 
Thiruvananthapuram
Is not multiple personality disorder 
A complex disorder which occurs in a person with unique 
individual, familial and social psychological profile 
Unknown, probably specific, environmental and 
psychological factors might contribute to the development 
of the disorder 
No one therapeutic approach is adequate to deal with this 
multifaceted disorder
How the patient has 
been affected? 
How the patient can be 
helped by the treatment?
Pharmacological 
Psychological 
Social strategies
Diagnosis 
Stabilization of medications 
Patient’s safety – suicidal or homicidal ideation 
Grossly disorganized or inappropriate behavior – 
inability to take care of food, clothing and shelter
Reduces patient’s stress 
Helps the patient to structure the daily activities 
Short stays of 4-6 weeks is as effective as long term 
hospitalization 
Hospital settings with active behavioral approaches 
produce better results than do custodial institutions
Mainstay of treatment 
Treat the symptoms 
Not cure 
About 2-4 times as many patients relapse when treated with 
a placebo as do those treated with antipsychotic drugs
Typical 
antipsychotic 
drugs 
Atypical 
antipsychotic 
drugs
What are the major distressing symptoms? 
Has the patient ever responded any 
particular medicine in the past? 
Has the patient taken treatment with drugs 
for adequate period of time (4-6 weeks)
Poor response to two different drugs when given in 
adequate dose for adequate period of time? 
Unpleasant reaction to first dose or unpleasant 
reaction during the initial week – subjective negative 
feeling, over-sedation, any severe side effects? 
Severe depression or irritability or excitement?
 Helps to increase 
 Social abilities 
 Self sufficiency 
 Practical skills 
 Interpersonal 
communication 
Social skills Training 
Family Therapy 
Group Therapy 
Cognitive Behavior therapy 
Individual Psychotherapy 
Vocational Therapy
 Has shown to reduce relapse rates as measured 
by need for hospitalization 
 Relationship problems 
 Poor eye contact 
 Unusual delays in response 
 Odd facial expressions 
 Lack of spontaneity in social situations 
 Inaccurate perceptions 
 Lack of perceptions of emotions in other individuals
 When family plays a role in precipitation of 
symptoms, perpetuation of symptoms or 
maintenance of symptoms
Focus is on: 
Effective in reducing 
social isolation, increasing 
sense of cohesiveness and 
improving reality testing 
Real life plans Real life problems Relationships
Helps to 
reduce: 
Cognitive 
distortions 
Reduces 
distractibility 
Correct errors 
of judgment 
Ameliorates 
delusions and 
hallucinations
Effect additive to 
pharmacotherapy 
Helps develop good personal 
relationship with therapist – a 
predictor of outcome.
Sheltered workshops 
Job clubs 
Part time employment 
Transitional employment programs
Visit an individual with Schizophrenia whom you 
know 
Spend some time with him/her 
If you don’t know anybody, take a decision that you 
will care for any individual with schizophrenia, if 
ever you come across
Medicine is not the treatment of choice for 
schizophrenia 
Ask your doctor for what 
nonpharmacological methods are good 
and effective for your relative with 
schizophrenia.
Treating Schizophrenia With Pharmacological and Non-Pharmacological Approaches

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Treating Schizophrenia With Pharmacological and Non-Pharmacological Approaches

  • 1. Dr. S. Krishnan Associate Professor of Psychiatry Government Medical College Thiruvananthapuram
  • 2.
  • 3. Is not multiple personality disorder A complex disorder which occurs in a person with unique individual, familial and social psychological profile Unknown, probably specific, environmental and psychological factors might contribute to the development of the disorder No one therapeutic approach is adequate to deal with this multifaceted disorder
  • 4. How the patient has been affected? How the patient can be helped by the treatment?
  • 6. Diagnosis Stabilization of medications Patient’s safety – suicidal or homicidal ideation Grossly disorganized or inappropriate behavior – inability to take care of food, clothing and shelter
  • 7. Reduces patient’s stress Helps the patient to structure the daily activities Short stays of 4-6 weeks is as effective as long term hospitalization Hospital settings with active behavioral approaches produce better results than do custodial institutions
  • 8. Mainstay of treatment Treat the symptoms Not cure About 2-4 times as many patients relapse when treated with a placebo as do those treated with antipsychotic drugs
  • 9. Typical antipsychotic drugs Atypical antipsychotic drugs
  • 10. What are the major distressing symptoms? Has the patient ever responded any particular medicine in the past? Has the patient taken treatment with drugs for adequate period of time (4-6 weeks)
  • 11. Poor response to two different drugs when given in adequate dose for adequate period of time? Unpleasant reaction to first dose or unpleasant reaction during the initial week – subjective negative feeling, over-sedation, any severe side effects? Severe depression or irritability or excitement?
  • 12.  Helps to increase  Social abilities  Self sufficiency  Practical skills  Interpersonal communication Social skills Training Family Therapy Group Therapy Cognitive Behavior therapy Individual Psychotherapy Vocational Therapy
  • 13.  Has shown to reduce relapse rates as measured by need for hospitalization  Relationship problems  Poor eye contact  Unusual delays in response  Odd facial expressions  Lack of spontaneity in social situations  Inaccurate perceptions  Lack of perceptions of emotions in other individuals
  • 14.  When family plays a role in precipitation of symptoms, perpetuation of symptoms or maintenance of symptoms
  • 15. Focus is on: Effective in reducing social isolation, increasing sense of cohesiveness and improving reality testing Real life plans Real life problems Relationships
  • 16. Helps to reduce: Cognitive distortions Reduces distractibility Correct errors of judgment Ameliorates delusions and hallucinations
  • 17. Effect additive to pharmacotherapy Helps develop good personal relationship with therapist – a predictor of outcome.
  • 18. Sheltered workshops Job clubs Part time employment Transitional employment programs
  • 19. Visit an individual with Schizophrenia whom you know Spend some time with him/her If you don’t know anybody, take a decision that you will care for any individual with schizophrenia, if ever you come across
  • 20. Medicine is not the treatment of choice for schizophrenia Ask your doctor for what nonpharmacological methods are good and effective for your relative with schizophrenia.