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Enteral and
Parenteral
Nutrition Support
Dr Ashish Tripathi
Gen Surgery PGT,
RTIICS, Kolkata.
Enteral Nutrition Definition
Nutritional support via placement through
the nose, esophagus, stomach, or intestines
(duodenum or jejunum)
—Tube feedings
—Must have functioning GI tract
—IF THE GUT WORKS, USE IT!
—Exhaust all oral diet methods first.
Conditions That Require Other
Nutrition Support
Enteral
—Impaired ingestion
—Inability to consume adequate nutrition
orally
—Impaired digestion, absorption, metabolism
—Severe wasting or depressed growth
Parenteral
—Gastrointestinal incompetency
—Hypermetabolic state with poor enteral
tolerance or accessibility
Considerations in Enteral Nutrition
1. Applicable
2. Site placement
3. Formula selection
4. Nutritional/medical requirements
5. Rate and method of delivery
6. Tolerance
Formula Selection
The suitability of a feeding formula should be
evaluated based on
Functional status of GI tract
Physical characteristics of formula (osmolality,
fiber content, caloric density, viscosity)
Macronutrient ratios
Digestion and absorption capability of patient
Specific metabolic needs
Contribution of the feeding to fluid and electrolyte
needs or restriction
Cost effectiveness
Enteral Access: Clinical Considerations
Duration of tube feeding
—Nasogastric or nasoenteric tube for short term
—Gastrostomy and jejunostomy tubes for
long term
Placement of tube
—Gastric
—Small bowel
Placement Site
Access (medical status)
Location (radiographic confirmation)
Duration
Tube measurements and durability
Adequacy of GI functioning
Enteral Tube Placement
Advantages—Enteral Nutrition
Intake easily/accurately monitored
Provides nutrition when oral is not
possible or adequate
Costs less than parenteral nutrition
Supplies readily available
Reduces risks associated with
disease state
More Advantages—
Enteral Nutrition
Preserves gut integrity
Decreases likelihood of bacterial
translocation
Preserves immunologic function of gut
Increased compliance with intake
Disadvantages—Enteral Nutrition
GI, metabolic, and mechanical complications
—tube migration; increased risk of bacterial
contamination; tube obstruction;
pneumothorax
Costs more than oral diets
Less “palatable/normal”
Labor-intensive assessment, administration,
tube patency and site care, monitoring
Complications of Enteral Feeding
Access problems (tube obstruction)
Administration problems (aspiration)
Gastrointestinal complications (diarrhea)
Metabolic complications (overhydration)
Aspiration Pneumonia
Can result from enteral feeds
High-risk patients
—Poor gag reflex
—Depressed mental status
Reducing Risk of Aspiration
Check gastric residuals if receiving gastric
feeds
Elevate head of the bed >30 degrees during
feedings
Postpyloric feeding
—Nasoenteric tube placement may require
fluoroscopic visualization or endoscopic
guidance
—Transgastric jejunostomy tube
Rate and Method of Delivery*
Bolus—300 to 400 ml rapid delivery via
syringe several times daily
Intermittent─300 to 400 ml, 20 to 30 minutes,
several times/day via gravity drip or syringe
Cyclic—via pump usually at night
Continuous—via gravity drip or infusion pump
*Determined by medical status, feeding route and
volume, and nutritional goals
Lower Osmolality
Large (intact) proteins
Large starch molecules
Higher Osmolality
Hydrolyzed protein or amino acids
Disaccharides
Tolerance
Signs and symptoms:
—Consciousness
—Respiratory distress
—Nausea, vomiting, diarrhea
—Constipation, cramps
—Aspiration
—Abdominal distention
Tolerance—cont’d
Other signs and symptoms
—Hydration
—Labs
—Weight change
—Esophageal reflux
—Lactose/gluten intolerances
—Glucose fluctuations
How to Determine Energy and
Protein
kcal/ml x ml given = kcal
% protein x kcal = kcal as protein
kcal as protein x 1 g/4 kcal = g protein
Example: Patient drinks 200 cc of a 15.3%
protein product that has 1 kcal/ml
1 kcal/ml x 200 ml = 200 kcal
0.153 % protein x 200 kcal = 30.6 kcal
30.6 kcal x 1g protein/4 kcal= 7.65 g protein
Energy in Formulas
1 to 1.2 kcal/ml = usual concentration
2 kcal/ml = highest concentration
Protein
From 4% to 26% of kcal is possible
14% to 16% of kcal is usual
18% to 26% of kcal—considered to be
high-protein solution
Recommended Water
Healthy adult: 1 ml/kcal or 35 ml/kg
Healthy infant: 1.5 ml/kcal or 150 ml/kg
Normal tube feeding: 1 kcal/ml; 80% to
85% water
Elderly: consider 25 ml/kg with renal, liver,
or cardiac failure; or consider 35 ml/kg if
history of dehydration
Sources of Fluid (“Free Water”)
Liquids
Water in food
Water from metabolism
With tube feeding, nurse will flush tube with
water about 3 times daily—include this
amount in estimated needs
—Example: “flush with 200 cc tid”
Administration: Feeding Rate
Continuous method = slow rate of 50 to 150
ml/hr for 12 to 24 hours
Intermittent method = 250 to 400 ml of
feeding given in 5 to 8 feedings per 24 hours
Bolus method = may give 300 to 400 ml
several time a day (“push” is not desired)
French Units—Tube Size
Diameter of feeding tube is measured in
French units
1F = 33 mm diameter
Feeding tube sizes differ for formula types
and administration techniques.
Enteral Nutrition Monitoring
Routes of Parenteral Nutrition
Central access
—TPN both long- and short-term placement
Peripheral or PPN
—New catheters allow longer support via
this method limited to 800 to 900 mOsm/kg
due to thrombophlebitis
<2000 kcal required or <10 days
PPN vs. TPN
Kcal required
(10% dextrose max. PPN conc.)
Fluid tolerance
Osmolarity
Duration
Central line contraindicated
Venous Sites from Which the Superior Vena Cava
May Be Accessed
Advantages—Parenteral Nutrition
Provides nutrients when less than
2 to 3 feet of small intestine remains
Allows nutrition support when GI
intolerance prevents oral or enteral
support
Indications for Total
Parenteral Nutrition
GI non functioning
NPO >5 days
GI fistula
Acute pancreatitis
Short bowel syndrome
Malnutrition with >10% to 15 % weight loss
Nutritional needs not met; patient refuses food
Contraindications
GI tract works
Terminally ill
Only needed briefly (<14 days)
Calculating Nutrient Needs
Avoid excess kcal (> 40 kcal/kg)
Adults
kcal/kg BW
Obese—use desired BMI range or an
adjusted factor
Adjusted Body Weight
Adjusted IBW for obesity
Female:
([actual weight – IBW] x 0.32) + IBW
Male:
([actual weight – IBW] x 0.38) + IBW
Parenteral Components
Carbohydrate
glucose or dextrose monohydrate
3.4 kcal/g
Amino acids
3, 3.5, 5, 7, 8.5, 10% solutions
Fat
10% emulsions = 1.1 kcal/ml
20% emulsions = 2 kcal/ml
Protein Requirements
1.2 to 1.5 g protein/kg IBW
mild or moderate stress
2.5 g protein/kg IBW
burns or severe trauma
Carbohydrate Requirements
Max. 0.36 g/kg BW/hr
Excess glucose causes:
Increased minute ventilation
Increased CO2 production
Increased RQ
Increased O2 consumption
Lipogenesis and liver problems
Lipid Requirements
4% to 10% kcals given as lipid meets
EFA requirements; or 2% to 4% kcals
given as lineoleic acid
Usual range 25% to 35% max. 60% of
kcal or 2.5 g fat/kg
Other Requirements
Fluid—30 to 50 ml/kg
Electrolytes
Use acetate or chloride forms
to manage acidosis or alkalosis
Vitamins
Trace elements
Calculating the Osmolarity of a
Parenteral Nutrition Solution
1. Multiply the grams of dextrose per liter by 5.
Example: 50 g of dextrose x 5 = 250 mOsm/L
2. Multiply the grams of protein per liter by 10.
Example: 30 g of protein x 10 = 300 mOsm/L
3. Fat is isotonic and does not contribute to
osmolarity.
4. Electrolytes further add to osmolarity.
Total osmolarity = 250 + 300 = 500 mOsm/L
Compounding Methods
Total nutrient admixture of amino acids,
glucose, additives
3-in-1 solution of lipid, amino acids,
glucose, additives
Administration
Start slowly
(1 L 1st day; 2 L 2nd day)
Stop slowly
(reduce rate by half every 1 to 2 hrs
or switch to dextrose IV)
Cyclic give 12 to 18 hours per day
Monitoring and Complications
Infection
Hemodynamic stability
Catheter care
Refeeding syndrome
Refeeding Syndrome
Hypophosphatemia
Hyperglycemia
Fluid retention
Cardiac arrest
Monitor
Weight
(daily)
Blood
Daily
Electrolytes (Na+
, K+
, Cl-
)
Glucose
Acid-base status
3 times/week
BUN
Ca+,
P
Plasma transaminases
Monitor—cont’d
Blood
Twice/week
Ammonia
Mg
Plasma transaminases
Weekly
Hgb
Prothrombin time
Zn
Cu
Triglycerides
Monitor—cont’d
Urine:
Glucose and ketones (4-6/day)
Specific gravity or osmolarity (2-4/day)
Urinary urea nitrogen (weekly)
Other:
Volume infusate (daily)
Oral intake (daily) if applicable
Urinary output (daily)
Activity, temperature, respiration (daily)
WBC and differential (as needed)
Cultures (as needed)
Problems
PPN
Site irritation
TPN
1. Catheter sepsis
2. Placement problems
3. Metabolic
Document in Chart
Type of feeding formula and tube
Method (bolus, drip, pump)
Rate and water flush
Intake energy and protein
Tolerance, complications, and
corrective actions
Patient education
Now the onus is on you.

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Nutrition in surgical patients

  • 1. Enteral and Parenteral Nutrition Support Dr Ashish Tripathi Gen Surgery PGT, RTIICS, Kolkata.
  • 2.
  • 3. Enteral Nutrition Definition Nutritional support via placement through the nose, esophagus, stomach, or intestines (duodenum or jejunum) —Tube feedings —Must have functioning GI tract —IF THE GUT WORKS, USE IT! —Exhaust all oral diet methods first.
  • 4. Conditions That Require Other Nutrition Support Enteral —Impaired ingestion —Inability to consume adequate nutrition orally —Impaired digestion, absorption, metabolism —Severe wasting or depressed growth Parenteral —Gastrointestinal incompetency —Hypermetabolic state with poor enteral tolerance or accessibility
  • 5. Considerations in Enteral Nutrition 1. Applicable 2. Site placement 3. Formula selection 4. Nutritional/medical requirements 5. Rate and method of delivery 6. Tolerance
  • 6. Formula Selection The suitability of a feeding formula should be evaluated based on Functional status of GI tract Physical characteristics of formula (osmolality, fiber content, caloric density, viscosity) Macronutrient ratios Digestion and absorption capability of patient Specific metabolic needs Contribution of the feeding to fluid and electrolyte needs or restriction Cost effectiveness
  • 7. Enteral Access: Clinical Considerations Duration of tube feeding —Nasogastric or nasoenteric tube for short term —Gastrostomy and jejunostomy tubes for long term Placement of tube —Gastric —Small bowel
  • 8. Placement Site Access (medical status) Location (radiographic confirmation) Duration Tube measurements and durability Adequacy of GI functioning
  • 9.
  • 11.
  • 12. Advantages—Enteral Nutrition Intake easily/accurately monitored Provides nutrition when oral is not possible or adequate Costs less than parenteral nutrition Supplies readily available Reduces risks associated with disease state
  • 13. More Advantages— Enteral Nutrition Preserves gut integrity Decreases likelihood of bacterial translocation Preserves immunologic function of gut Increased compliance with intake
  • 14. Disadvantages—Enteral Nutrition GI, metabolic, and mechanical complications —tube migration; increased risk of bacterial contamination; tube obstruction; pneumothorax Costs more than oral diets Less “palatable/normal” Labor-intensive assessment, administration, tube patency and site care, monitoring
  • 15. Complications of Enteral Feeding Access problems (tube obstruction) Administration problems (aspiration) Gastrointestinal complications (diarrhea) Metabolic complications (overhydration)
  • 16.
  • 17. Aspiration Pneumonia Can result from enteral feeds High-risk patients —Poor gag reflex —Depressed mental status
  • 18. Reducing Risk of Aspiration Check gastric residuals if receiving gastric feeds Elevate head of the bed >30 degrees during feedings Postpyloric feeding —Nasoenteric tube placement may require fluoroscopic visualization or endoscopic guidance —Transgastric jejunostomy tube
  • 19. Rate and Method of Delivery* Bolus—300 to 400 ml rapid delivery via syringe several times daily Intermittent─300 to 400 ml, 20 to 30 minutes, several times/day via gravity drip or syringe Cyclic—via pump usually at night Continuous—via gravity drip or infusion pump *Determined by medical status, feeding route and volume, and nutritional goals
  • 20. Lower Osmolality Large (intact) proteins Large starch molecules
  • 21. Higher Osmolality Hydrolyzed protein or amino acids Disaccharides
  • 22. Tolerance Signs and symptoms: —Consciousness —Respiratory distress —Nausea, vomiting, diarrhea —Constipation, cramps —Aspiration —Abdominal distention
  • 23. Tolerance—cont’d Other signs and symptoms —Hydration —Labs —Weight change —Esophageal reflux —Lactose/gluten intolerances —Glucose fluctuations
  • 24. How to Determine Energy and Protein kcal/ml x ml given = kcal % protein x kcal = kcal as protein kcal as protein x 1 g/4 kcal = g protein Example: Patient drinks 200 cc of a 15.3% protein product that has 1 kcal/ml 1 kcal/ml x 200 ml = 200 kcal 0.153 % protein x 200 kcal = 30.6 kcal 30.6 kcal x 1g protein/4 kcal= 7.65 g protein
  • 25. Energy in Formulas 1 to 1.2 kcal/ml = usual concentration 2 kcal/ml = highest concentration
  • 26. Protein From 4% to 26% of kcal is possible 14% to 16% of kcal is usual 18% to 26% of kcal—considered to be high-protein solution
  • 27. Recommended Water Healthy adult: 1 ml/kcal or 35 ml/kg Healthy infant: 1.5 ml/kcal or 150 ml/kg Normal tube feeding: 1 kcal/ml; 80% to 85% water Elderly: consider 25 ml/kg with renal, liver, or cardiac failure; or consider 35 ml/kg if history of dehydration
  • 28. Sources of Fluid (“Free Water”) Liquids Water in food Water from metabolism With tube feeding, nurse will flush tube with water about 3 times daily—include this amount in estimated needs —Example: “flush with 200 cc tid”
  • 29. Administration: Feeding Rate Continuous method = slow rate of 50 to 150 ml/hr for 12 to 24 hours Intermittent method = 250 to 400 ml of feeding given in 5 to 8 feedings per 24 hours Bolus method = may give 300 to 400 ml several time a day (“push” is not desired)
  • 30. French Units—Tube Size Diameter of feeding tube is measured in French units 1F = 33 mm diameter Feeding tube sizes differ for formula types and administration techniques.
  • 32. Routes of Parenteral Nutrition Central access —TPN both long- and short-term placement Peripheral or PPN —New catheters allow longer support via this method limited to 800 to 900 mOsm/kg due to thrombophlebitis <2000 kcal required or <10 days
  • 33. PPN vs. TPN Kcal required (10% dextrose max. PPN conc.) Fluid tolerance Osmolarity Duration Central line contraindicated
  • 34. Venous Sites from Which the Superior Vena Cava May Be Accessed
  • 35. Advantages—Parenteral Nutrition Provides nutrients when less than 2 to 3 feet of small intestine remains Allows nutrition support when GI intolerance prevents oral or enteral support
  • 36. Indications for Total Parenteral Nutrition GI non functioning NPO >5 days GI fistula Acute pancreatitis Short bowel syndrome Malnutrition with >10% to 15 % weight loss Nutritional needs not met; patient refuses food
  • 37. Contraindications GI tract works Terminally ill Only needed briefly (<14 days)
  • 38. Calculating Nutrient Needs Avoid excess kcal (> 40 kcal/kg) Adults kcal/kg BW Obese—use desired BMI range or an adjusted factor
  • 39. Adjusted Body Weight Adjusted IBW for obesity Female: ([actual weight – IBW] x 0.32) + IBW Male: ([actual weight – IBW] x 0.38) + IBW
  • 40. Parenteral Components Carbohydrate glucose or dextrose monohydrate 3.4 kcal/g Amino acids 3, 3.5, 5, 7, 8.5, 10% solutions Fat 10% emulsions = 1.1 kcal/ml 20% emulsions = 2 kcal/ml
  • 41. Protein Requirements 1.2 to 1.5 g protein/kg IBW mild or moderate stress 2.5 g protein/kg IBW burns or severe trauma
  • 42. Carbohydrate Requirements Max. 0.36 g/kg BW/hr Excess glucose causes: Increased minute ventilation Increased CO2 production Increased RQ Increased O2 consumption Lipogenesis and liver problems
  • 43. Lipid Requirements 4% to 10% kcals given as lipid meets EFA requirements; or 2% to 4% kcals given as lineoleic acid Usual range 25% to 35% max. 60% of kcal or 2.5 g fat/kg
  • 44.
  • 45. Other Requirements Fluid—30 to 50 ml/kg Electrolytes Use acetate or chloride forms to manage acidosis or alkalosis Vitamins Trace elements
  • 46. Calculating the Osmolarity of a Parenteral Nutrition Solution 1. Multiply the grams of dextrose per liter by 5. Example: 50 g of dextrose x 5 = 250 mOsm/L 2. Multiply the grams of protein per liter by 10. Example: 30 g of protein x 10 = 300 mOsm/L 3. Fat is isotonic and does not contribute to osmolarity. 4. Electrolytes further add to osmolarity. Total osmolarity = 250 + 300 = 500 mOsm/L
  • 47. Compounding Methods Total nutrient admixture of amino acids, glucose, additives 3-in-1 solution of lipid, amino acids, glucose, additives
  • 48. Administration Start slowly (1 L 1st day; 2 L 2nd day) Stop slowly (reduce rate by half every 1 to 2 hrs or switch to dextrose IV) Cyclic give 12 to 18 hours per day
  • 49. Monitoring and Complications Infection Hemodynamic stability Catheter care Refeeding syndrome
  • 50.
  • 51.
  • 53. Monitor Weight (daily) Blood Daily Electrolytes (Na+ , K+ , Cl- ) Glucose Acid-base status 3 times/week BUN Ca+, P Plasma transaminases
  • 55. Monitor—cont’d Urine: Glucose and ketones (4-6/day) Specific gravity or osmolarity (2-4/day) Urinary urea nitrogen (weekly) Other: Volume infusate (daily) Oral intake (daily) if applicable Urinary output (daily) Activity, temperature, respiration (daily) WBC and differential (as needed) Cultures (as needed)
  • 56. Problems PPN Site irritation TPN 1. Catheter sepsis 2. Placement problems 3. Metabolic
  • 57. Document in Chart Type of feeding formula and tube Method (bolus, drip, pump) Rate and water flush Intake energy and protein Tolerance, complications, and corrective actions Patient education
  • 58.
  • 59.
  • 60. Now the onus is on you.