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KELOID DISEASE
(Case Presentation)
PRESENTED BY
Antony Mamati.
We see what we want?
Common things are usually very rare to spot.
History
 A 23 year old female was referred by
plastic surgeons for radiotherapy to the
posterior ear lobe, following the
development of a Keloid Scar, three
years after an ear piercing
 No family history of keloids
Pathology
 Keloid is a unique human dermal
fibroproliferative disorder that occurs after injury,
inflammation, surgery,and burn.
 Commonly causes of keloids include acne,
folliculitis, chicken pox, vaccinations and trauma
(such as, earlobe piercing, lacerations, or surgical
wounds).
 It is a benign growth, well-demarcated area of
fibrous tissue overgrowth that extends beyond the
original defect
Baron Jean-Louis Alibert
(1768-1837)
Described appearance “Chele” (crab-claw)
 (also means: to grab as in “chelation”)
Crab-claw-like  Cheloid  Keloid
Effects of keloids
Compromise aesthetic Impairment of function
 Itchy
 Pain
 Prurutic
How best can they be treated?
Treatment Options
 Surgery
 Intralesional Steroids
 Radiation
 Laser
 Cryotherapy
 Pressure
 Multimodality Therapy
Still Trying
Surgery Drawbacks
 Painful
 Difficult reconstruction with large keloids
 Utilizes normal surrounding tissue – limiting later
reconstructive options
 Low long term success as monotherapy
Steroids
 Triamcinolone
 Hydrocortisone
 Dexamethasone
 Methylprednisone
Laser
 1980s in vogue
 Proposed Mechanism
No knife  Less tissue trauma
Cryotherapy- cold treatment
 Diminishes size and induration (HTS >Keloid) when
used as monotherapy
 <10% Recurrence when combined with surgery
Photos Courtesy of Dr. Redett
Pressure Therapy
Radiation
Multimodullar
In this case…
 Plastic surgery was carried out to remove the Keloid
Scar. The patient attended the following day for a
single dose of radiotherapy to the scar, plus a small
margin of 5mm. The pinna was taped forward to
expose the effected posterior section of the lobe.
Radiotherapy prescription
12Gy in single fraction.
 HVL 0.2mm Cu
 Energy used was:- 100kv.
 Actual Field size:- 3.5 x 1.5 cm –margins of
2mm
 Cone size used:- 4 X 6cm
 Shielding :-A lead cut out was used to
define the field size and protect the
surrounding
 tissue.
Conclusion
A case to think
 A 32 year old
female
 Para 1+0
 No family history
of keloid
 Developed keloid
after c-section
 Had steroidal
injection 4
courses.
Thank You

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Keloids main

  • 2. We see what we want? Common things are usually very rare to spot.
  • 3. History  A 23 year old female was referred by plastic surgeons for radiotherapy to the posterior ear lobe, following the development of a Keloid Scar, three years after an ear piercing  No family history of keloids
  • 4. Pathology  Keloid is a unique human dermal fibroproliferative disorder that occurs after injury, inflammation, surgery,and burn.  Commonly causes of keloids include acne, folliculitis, chicken pox, vaccinations and trauma (such as, earlobe piercing, lacerations, or surgical wounds).  It is a benign growth, well-demarcated area of fibrous tissue overgrowth that extends beyond the original defect
  • 5. Baron Jean-Louis Alibert (1768-1837) Described appearance “Chele” (crab-claw)  (also means: to grab as in “chelation”) Crab-claw-like  Cheloid  Keloid
  • 6. Effects of keloids Compromise aesthetic Impairment of function
  • 8. How best can they be treated?
  • 9. Treatment Options  Surgery  Intralesional Steroids  Radiation  Laser  Cryotherapy  Pressure  Multimodality Therapy
  • 11. Surgery Drawbacks  Painful  Difficult reconstruction with large keloids  Utilizes normal surrounding tissue – limiting later reconstructive options  Low long term success as monotherapy
  • 12. Steroids  Triamcinolone  Hydrocortisone  Dexamethasone  Methylprednisone
  • 13.
  • 14. Laser  1980s in vogue  Proposed Mechanism No knife  Less tissue trauma
  • 16.  Diminishes size and induration (HTS >Keloid) when used as monotherapy  <10% Recurrence when combined with surgery Photos Courtesy of Dr. Redett Pressure Therapy
  • 19. In this case…  Plastic surgery was carried out to remove the Keloid Scar. The patient attended the following day for a single dose of radiotherapy to the scar, plus a small margin of 5mm. The pinna was taped forward to expose the effected posterior section of the lobe.
  • 20. Radiotherapy prescription 12Gy in single fraction.  HVL 0.2mm Cu  Energy used was:- 100kv.  Actual Field size:- 3.5 x 1.5 cm –margins of 2mm  Cone size used:- 4 X 6cm  Shielding :-A lead cut out was used to define the field size and protect the surrounding  tissue.
  • 22. A case to think  A 32 year old female  Para 1+0  No family history of keloid  Developed keloid after c-section  Had steroidal injection 4 courses.