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Susanna-Assunta Sansone, PhD Team Leader,  University of Oxford, UK Biocuration, 11 th -14 th  October 2010, Tokyo, Japan Omics Data Sharing BioSharing:  on Data Policies’s Plans  and Reporting Standards   Innovative technology accelerating research
Information intensive research investigations The International Conference on Systems Biology (ICSB) , 22-28 August, 2008  Susanna-Assunta Sansone  www.ebi.ac.uk/net-project ,[object Object],[object Object]
Comprehensible, reusable, reproducible research  The International Conference on Systems Biology (ICSB) , 22-28 August, 2008  Susanna-Assunta Sansone  www.ebi.ac.uk/net-project ,[object Object]
The International Conference on Systems Biology (ICSB) , 22-28 August, 2008  Susanna-Assunta Sansone  www.ebi.ac.uk/net-project ,[object Object],[object Object],[object Object],[object Object],Reporting standards as enablers
Strong advocators The International Conference on Systems Biology (ICSB) , 22-28 August, 2008  Susanna-Assunta Sansone  www.ebi.ac.uk/net-project ,[object Object],[object Object],[object Object]
...funders are developing data policies... ,[object Object]
....similar trend in the regulatory arena ,[object Object]
....and commercial sector ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Reporting standards as a means to an end
Escalating number of efforts (omics domain),  e.g.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Heterogeneity of the efforts
Navigating a sea of ‘standards’
I work on plants, are these just for biomedical applications?  Which one are mature enough for me to use or recommend?  How can I get involved to propose extensions or modifications? Which tools and databases  implement  which one? Which one are widely accepted and recognized? What are the criteria to evaluate status and value? ...?....  ...?....  ....?...  ...?....  ....?...  ...?....  I use HT sequencing technologies, which one are applicable to me? Navigating a sea of ‘standards’ Which tools and databases  implement  which one? I use HT sequencing technologies, which one are applicable to me?
HT sequencing: public databases and ‘standards’ EBI NCBI ENA SRA
HT sequencing: public databases and ‘standards’ EBI NCBI ENA SRA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],INSDC  feature table
(2008) Vol 26 No 8 http://mibbi.org
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Linking checklists to terminologies http://www.ebi.ac.uk/ontology-lookup/ http://bioportal.bioontology.org/ http://www.obofoundry.org/
Science (2009), Vol 326, 234-236 http://biosharing.org
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
‘ Social engineering’ http://biosharing.org
[object Object],[object Object],[object Object],[object Object],[object Object],http://biosharing.org
 
 
 
[object Object],[object Object],[object Object],[object Object],http://biosharing.org
Part of our software development activities Rocca-Serra  et al , Bioinformatics , 2010 ISA software suite open source: www.isa-tools.org
Science , 2009 Bioinformatics , 2010 Nature Biotech , (invited)

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Sansone mibbi-intro

  • 1. Susanna-Assunta Sansone, PhD Team Leader, University of Oxford, UK Biocuration, 11 th -14 th October 2010, Tokyo, Japan Omics Data Sharing BioSharing: on Data Policies’s Plans and Reporting Standards   Innovative technology accelerating research
  • 2.
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  • 10. Escalating number of efforts (omics domain), e.g.
  • 11.
  • 12. Navigating a sea of ‘standards’
  • 13. I work on plants, are these just for biomedical applications? Which one are mature enough for me to use or recommend? How can I get involved to propose extensions or modifications? Which tools and databases implement which one? Which one are widely accepted and recognized? What are the criteria to evaluate status and value? ...?.... ...?.... ....?... ...?.... ....?... ...?.... I use HT sequencing technologies, which one are applicable to me? Navigating a sea of ‘standards’ Which tools and databases implement which one? I use HT sequencing technologies, which one are applicable to me?
  • 14. HT sequencing: public databases and ‘standards’ EBI NCBI ENA SRA
  • 15.
  • 16. (2008) Vol 26 No 8 http://mibbi.org
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  • 18. Linking checklists to terminologies http://www.ebi.ac.uk/ontology-lookup/ http://bioportal.bioontology.org/ http://www.obofoundry.org/
  • 19. Science (2009), Vol 326, 234-236 http://biosharing.org
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  • 23. ‘ Social engineering’ http://biosharing.org
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  • 29. Part of our software development activities Rocca-Serra et al , Bioinformatics , 2010 ISA software suite open source: www.isa-tools.org
  • 30. Science , 2009 Bioinformatics , 2010 Nature Biotech , (invited)