1. ACKNOWLEDGEMENT
First of all, I am deeply grateful to Allah. Coming from the intense
gratification of my supervisors whom their contribution has raised the quality
of this thesis. They have always supported me and have given me enthusiasm
for science. They have patiently guided me. I am very grateful to their
supervision and I owe them the greatest degree of appreciation.
I am deeply grateful and I wish to express my deepest gratitude to
Prof. Dr. Eatimad Ahmed Shoreibah
Professor of Oral Medicine, Periodontology, Oral Diagnosis and
Radiology, and prior Dean of Faculty of Dental Medicine( Girls` Branch)
AL-Azhar University for suggesting the point of the thesis, supervision of the
work and for the invaluable guidance, the longtime and tremendous effort to
offer every possible help to finish this thesis. It was a great honor to finish
this work under her supervision.
I am genuinely appreciative of Dr. Magda Ahmed
El Malt Lecture of Pediatric Dentistry Pedodontics Department, Faculty
of Dental Medicine (Girls` Branch) AL-Azhar University, for her valuable
scientific assistance and undoubted effort she had exerted during her
supervision of this work.
My thankfulness is also to the staff of the Department of Pediatric
Dentistry Pedodontics, Faculty of Dental Medicine (Girls` Branch)
AL-Azhar University especially Dr. Mohamed Hassan Mostafa
for their great support and their kind care.
My appreciation is also to the staff of the Department of Microbiology,
Faculty of Medicine, AL Azhar University, especially
Prof. Dr. Mahmoud Abd EL Hady and Dr.Ibrahim AL Husseiny
for their great effort.
My thankfulness is also to the staff of the Department of Nephrology,
Faculty of Medicine, AL Azhar University, ALmattaria hospital and Nasser

2. Institute for their great support, and thanks for all chikdren and their parents
who shared in this thesis.
Dedication
To my parents .
The reason of what I become today.
Thanks for your great support and
continous care.
To my sisters .
I am really grateful to both of your.
Yoy have been my imspiration, and my
soul mates

3. Dedication
Dedication

4. Dedi
cation
Dedication
Dedication