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Cell Growth and Division
Cell Division is the Cell’s way of Reproducing itself Reproduction is a Life Process     more of the same unit is formed    not essential for survival    is a need to perpetuate species
Chapter Objectives At the end of lecture discussion, the learners are expected to: Explain Cell Reproduction at the molecular level, with emphasis of the role of DNA and Chromosomes
Describe the limits to cell growth. Identify the types of cells in the body of an organism. Name and describe the sequence of stages in Mitosis and Meiosis.
 Describe the chromosamal changes in Mitosis and Meiosis.  Give the significance of cell division. Trace the formation of sperm and egg cells through the process of spermatogenesis and oogenesis.
Cell Growth & Reproduction
Review of Terms DNA Chromatids Histones Helix Chromosome Chromatin Nucleosomes
DNA Replication DNA possesses a remarkable ability to create copies of its own structure
DNA Replication cont’ REPLICATION Occurs as the double strand of DNA unzips at certain points (synthesis stage)
Limits of Cell Growth Cells of human adult are no larger than human babies. Cells eat and defecate Cells know to adapt Cells growth and division rate vary. Sometimes cell growth and division become uncontrollable (cancer cells)
Cells of the Human Body Somatic Cells Diploid number (2N) or complete set of (46) Chromosomes Ex. 		Skin Cells 		Lung Cells 		etc. Reproductive Cells Haploid number (N) or half (23) number of chromosomes. Ex. 		Sperm Cell 		Egg Cell
Assessment Break Explain the limits of Cell Growth. Why do cells divide? Distinguish between Somatic and Germ Cells Haploid and Diploid
MITOSIS During Mitosis Chromosomes duplicate and daughter cells receives the same amount of chromosomal material as the parent cell. Mitosis is the first step in growth and differentiation of somatic cells.
MITOSIS cont’ Interphase G1 ~ Presynthetic 	S ~ Synthetic 			Phase 	G2 ~ Postsynthetic 		stage
Interphase ( not a phase of Mitosis) Growth occurs as organelles double (G1) Chromosomes (DNA) duplicates (S) Growth occurs as cell prepares to divide (G2)
The Major Events of Cell Division Karyokinesis Splitting of the nucleus Inside nuclear events of the cell Cytokinesis Cytoplasmic Division Outside nuclear events of the cell
Mitosis
Phases of Mitosis Mitosis begins after Interphase Stages/Phases 		Prophase 		Metaphase 		Anaphase Telophase
Prophase Early Prophase Centrioles move to the poles of the cell Chromosomes appear as long, this threads Nucleus becomes less distinct Nuclear membrane is still visible Asters are formed
Prophase Middle Prophase Centrioles begin to organize spindle fibers Sister chromatids are formed with the centromere as point of attachment
Late Prophase ,[object Object]
Nuclear membrane slowly desintegrates
Nucleulus is no longer visible
Chromosome move toward the equatorProphase ,[object Object],[object Object]
Anaphase ,[object Object],Early Anaphase ,[object Object],[object Object]
Cytokinesis begins,[object Object]
2ndInterphase: 2 cell stage ,[object Object]
Chromosomes are no longer visible
Cytokinesis is complete
Two new daughter cells are formed, each with a complete set of materials as the parent cell,[object Object]
Brain cells do not dived when mature
Most frequent/fast in human embryo formation,[object Object]
Meiosis A cell division forming reproductive cells Oogenesis Spermatogenesis Occurs in two cycles of division
Meiosis Dissected: Stages Meiosis involves two consecutive divisions It involves “Crossing Over” or the exchange of DNA traits
1st  & 2nd Meiotic Division Parent  Sex Cells Chromosomes duplicate Crossing over 1st Cell division (2 daughter cells) 2 daughter cells Chromosomes pair up Chromosomes separate 2nd Cell Division) Cell divides into 4 sex cells with haploid chromosomes
Mitosis VS Meiosis
Gametogenesis ,[object Object],Spermatgenesis ~ formation of sperm cells Oogenesis ~ formation of egg cells

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Cell growth and division pp presention

  • 1. Cell Growth and Division
  • 2. Cell Division is the Cell’s way of Reproducing itself Reproduction is a Life Process more of the same unit is formed not essential for survival is a need to perpetuate species
  • 3. Chapter Objectives At the end of lecture discussion, the learners are expected to: Explain Cell Reproduction at the molecular level, with emphasis of the role of DNA and Chromosomes
  • 4. Describe the limits to cell growth. Identify the types of cells in the body of an organism. Name and describe the sequence of stages in Mitosis and Meiosis.
  • 5. Describe the chromosamal changes in Mitosis and Meiosis. Give the significance of cell division. Trace the formation of sperm and egg cells through the process of spermatogenesis and oogenesis.
  • 6. Cell Growth & Reproduction
  • 7. Review of Terms DNA Chromatids Histones Helix Chromosome Chromatin Nucleosomes
  • 8. DNA Replication DNA possesses a remarkable ability to create copies of its own structure
  • 9. DNA Replication cont’ REPLICATION Occurs as the double strand of DNA unzips at certain points (synthesis stage)
  • 10. Limits of Cell Growth Cells of human adult are no larger than human babies. Cells eat and defecate Cells know to adapt Cells growth and division rate vary. Sometimes cell growth and division become uncontrollable (cancer cells)
  • 11. Cells of the Human Body Somatic Cells Diploid number (2N) or complete set of (46) Chromosomes Ex. Skin Cells Lung Cells etc. Reproductive Cells Haploid number (N) or half (23) number of chromosomes. Ex. Sperm Cell Egg Cell
  • 12. Assessment Break Explain the limits of Cell Growth. Why do cells divide? Distinguish between Somatic and Germ Cells Haploid and Diploid
  • 13. MITOSIS During Mitosis Chromosomes duplicate and daughter cells receives the same amount of chromosomal material as the parent cell. Mitosis is the first step in growth and differentiation of somatic cells.
  • 14. MITOSIS cont’ Interphase G1 ~ Presynthetic S ~ Synthetic Phase G2 ~ Postsynthetic stage
  • 15. Interphase ( not a phase of Mitosis) Growth occurs as organelles double (G1) Chromosomes (DNA) duplicates (S) Growth occurs as cell prepares to divide (G2)
  • 16. The Major Events of Cell Division Karyokinesis Splitting of the nucleus Inside nuclear events of the cell Cytokinesis Cytoplasmic Division Outside nuclear events of the cell
  • 18. Phases of Mitosis Mitosis begins after Interphase Stages/Phases Prophase Metaphase Anaphase Telophase
  • 19. Prophase Early Prophase Centrioles move to the poles of the cell Chromosomes appear as long, this threads Nucleus becomes less distinct Nuclear membrane is still visible Asters are formed
  • 20. Prophase Middle Prophase Centrioles begin to organize spindle fibers Sister chromatids are formed with the centromere as point of attachment
  • 21.
  • 22. Nuclear membrane slowly desintegrates
  • 23. Nucleulus is no longer visible
  • 24.
  • 25.
  • 26.
  • 27.
  • 28. Chromosomes are no longer visible
  • 30.
  • 31. Brain cells do not dived when mature
  • 32.
  • 33. Meiosis A cell division forming reproductive cells Oogenesis Spermatogenesis Occurs in two cycles of division
  • 34. Meiosis Dissected: Stages Meiosis involves two consecutive divisions It involves “Crossing Over” or the exchange of DNA traits
  • 35. 1st & 2nd Meiotic Division Parent Sex Cells Chromosomes duplicate Crossing over 1st Cell division (2 daughter cells) 2 daughter cells Chromosomes pair up Chromosomes separate 2nd Cell Division) Cell divides into 4 sex cells with haploid chromosomes
  • 37.
  • 38. Spermatogenesis The formation of male gametes An example of Meiosis
  • 39. Oogenesis Formation of Female Gamete An example of Meiosis
  • 41. Assessment Break Define meiosis. How is it different from mitosis? How many cells are formed after the first cell division in meiosis? After the second division? What is gametogenesis? Compare and contrast spermatogenesis and oogenesis.