Natal van Riel

systems biology systems medicine uncertainty analysis parameter estimation metabolism metabolic syndrome estimating models of dynamic systems adapt hepatic steatosis hdl computational modeling metabolic network modelling identifiability data integration m-health diabetes eindhoven verification validation uncertainty quantification regularization quantitative systems pharmacology lipoprotein distribution profiling lipoprotein metabolism mouse models aging lxr fluxomics lipid metabolism differential equation models human metabolism metabolomics metabolic network physiology-based model human glucoregulatory system diabetes self-management education (dsme) glucose games for health systems physiology education biomedical engineering genome-scale metabolic models