121130 NECFW Sound Bite
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These are the slides from my sound bite at the 53rd New England Complex Fluids Workgroup at Harvard University.
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121130 NECFW Sound Bite
- 1. Mapping Physiological Heterogeneities in Biofilms Naveen Sinha J Wilking, A Seminara, D Weitz, and M Brenner Harvard School of Engineering and Applied Sciences
- 3. Despite being genetically identical, cells differentiate into different types. Lopez 2010
- 4. We can use fluorescent reporters to visually identify different cell types. Lopez 2010
- 5. Can we quantitatively describe when and where cell types become active? 8 hours 16 hours 24 hours 32 hours
- 6. Can the locations and timing of cell types be explained by only nutrients? Lopez 2010
- 7. …or are chemical signals also needed to explain the patterns that form? Lopez 2010
- 8. We can azimuthally average the intensity to simplify to one dimension. Intensity Radial distance
- 9. Each image is transformed into a two dimensional plot… 8 hours 16 hours 24 hours 32 hours CFP (matrix) R R R R
- 10. Each image is transformed into a two dimensional plot… Matrix production Spore production radius ( m) radius ( m)
- 11. Are the peaks in gene expression levels correlated with the nutrient concentrations? CFP (matrix) R R R R 8 hours 16 hours 24 hours 32 hours Agnese Seminara